A meta-analysis published in The Lancet Oncology reveals that men with intermediate- and high-risk prostate cancer experience improved overall survival with the addition of hormone therapy to radiotherapy. The study found prolonged adjuvant hormone therapy benefits men, while neoadjuvant hormone therapy did not.
SourceUniversity Hospitals Cleveland Medical Center·JournalThe Lancet Oncology·TypeMeta-analysis·DateJan 18, 2022
A newly identified molecular signal can spot aggressive tumor cells in early prostate cancers, allowing for targeted treatment. Researchers at Duke University Medical Center have developed a test to guide treatment based on this genomic signature.
SourceDuke University Medical Center·JournalEuropean Urology·DateJan 18, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A recent analysis of 7.8 million VA patients found significant disparities in localized and metastatic prostate cancer incidence between African Americans and whites. The study highlights the need for targeted interventions to address racial gaps in prostate cancer care.
SourceJAMA Network·JournalJAMA Network Open·DateJan 18, 2022
A large international evaluation shows AI systems can identify and grade prostate cancer in tissue samples from different countries equally well as human pathologists. The results suggest AI can be a complementary tool in prostate cancer care, improving diagnostic quality and consistency.
SourceKarolinska Institutet·JournalNature Medicine·DateJan 13, 2022
Researchers aimed to tackle racial disparities in prostate cancer by targeting educational interventions to populations at highest risk. A study in Philadelphia neighborhoods found that prostate-specific education improved knowledge and intention to screen, with similar effects on control groups.
SourceThomas Jefferson University·JournalJournal of Racial and Ethnic Health Disparities·TypeSurvey·DateJan 13, 2022
A UCI-led team identified a molecular feature in prostate cancer associated with ancestry, which may help predict patient risk and tailor treatment. ERV expression signatures also showed promise for identifying patients at greatest risk of progression across different ancestries.
SourceUniversity of California - Irvine·JournalCancers·DateJan 11, 2022
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
The Society of Nuclear Medicine and Molecular Imaging has published appropriate use criteria (AUC) for prostate-specific membrane antigen (PSMA) PET imaging. The guidelines provide a framework for healthcare providers to determine the most effective use of PSMA PET scans in patients with suspected or known prostate cancer.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJan 7, 2022
A portable prostate cancer screening kit could provide early warning to populations with higher incidence of prostate cancer, particularly African American men. The test uses a test strip and reader to quantify PSA from a drop of blood in minutes, delivering results in 10-15 minutes.
SourceCornell University·JournalCurrent Research in Biotechnology·DateJan 4, 2022
The study combined seven randomized clinical trials with 8,000 patients to compare overall and treatment-specific outcomes of Black and white men with localized prostate cancer who received radiation therapy. The results showed that there were significant racial disparities in response to radiation therapy for prostate cancer.
SourceJAMA Network·JournalJAMA Network Open·DateDec 29, 2021
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A meta-analysis of seven randomized trials found that Black men with localized prostate cancer had lower recurrence, metastasis, and mortality rates compared to white men. The study challenges the common belief that Black men with prostate cancer have a worse prognosis.
SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Network Open·TypeMeta-analysis·DateDec 29, 2021
Researchers discover a chromatin degrader that blocks cancer-causing genes, offering potential treatment for over 90% of prostate cancers. The study found that blocking the SWI/SNF complex slowed cancer cell growth and induced cell death, especially in tumors driven by FOXA1 or androgen receptor.
SourceMichigan Medicine - University of Michigan·JournalNature·TypeExperimental study·DateDec 27, 2021
Researchers have identified NDUFS1 and ATP5O as novel markers of aggressive prostate cancer, associated with poorer survival rates. The study's findings provide new insights into the disease's molecular mechanisms and potential targets for therapy.
SourceMedical University of Vienna·JournalCancers·DateDec 22, 2021
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A clinical study and register studies have failed to confirm previous findings that a medicine blocking testosterone could help against COVID-19. The researchers found no discernible signs of the drug having any beneficial effect on participants' health status.
SourceUniversity of Gothenburg·JournalEuropean Urology·TypeRandomized controlled/clinical trial·DateDec 16, 2021
Surgeons at Henry Ford Health performed the world's first precision prostatectomy through the bladder using a single port robotic surgical system. The procedure preserves a portion of the prostate capsule, improving functional outcomes such as erectile function and urinary control.
SourceHenry Ford Health·JournalEuropean Urology·DateDec 13, 2021
A study found that men with Li-Fraumeni syndrome have a 25-fold increased risk of developing aggressive prostate cancer, and those with inherited TP53 variants are diagnosed at a young age. Routine screening for prostate cancer is recommended for these individuals.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalEuropean Urology·TypeData/statistical analysis·DateDec 10, 2021
A team from the University of Washington has developed a non-destructive 3D imaging method that can help doctors more accurately diagnose borderline cases of prostate cancer. The new approach uses 3D images to identify complex features in tissue samples, which can increase the likelihood of correctly predicting a cancer's aggressiveness.
SourceUniversity of Washington·JournalCancer Research·DateDec 9, 2021
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
After the 2012 US Preventive Services Task Force (USPSTF) statement discouraging routine prostate-specific antigen (PSA) testing, rates of prostate cancer screening and biopsy decreased across racial groups. However, Black men had higher rates of local and metastatic prostate cancer despite similar screening rates.
SourceWolters Kluwer Health·JournalUrology Practice·DateDec 2, 2021
A study at Tampere University in Finland found that statin users had lower rates of low-risk prostate cancers detected through screening, but no difference in high-risk cancer detection. Statin use also reduced prostate cancer mortality in screened men compared to unscreened men.
SourceTampere University·JournalJAMA Oncology·DateNov 29, 2021
Researchers at Princeton University have discovered a new compound that can disable the MTDH gene, which is essential for cancer progression and metastasis. The compound shows promise in treating major human cancers, including breast, prostate, lung, and colon cancers.
SourcePrinceton University·JournalNature Cancer·TypeExperimental study·DateNov 29, 2021
Researchers found that dysregulation of enzymes in the glucuronidation pathway is associated with castration-resistant prostate cancer. The study suggests that reducing UGDH expression and/or activity can reverse castration resistance, potentially preventing or delaying therapeutic resistance.
SourceImpact Journals LLC·JournalOncotarget·DateNov 16, 2021
Researchers have developed a new approach to studying prostate cancer, allowing them to track the behavior of individual cancer cells from birth to organ spread. The technique uses whole-organ imaging and artificial intelligence to create a 3D reconstruction of the organ at single-cell resolution.
SourceCold Spring Harbor Laboratory·JournalCell Reports·DateNov 16, 2021
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers produce large quantities of powerful cancer-fighting iNKT cells using stem cell engineering and organoid technology, offering a potential solution for mass-producing an off-the-shelf immune cell therapy. The therapy, which uses hematopoietic stem cell-engineered iNKT cells, has been shown to be effective in killing multiple...
SourceUniversity of California - Los Angeles Health Sciences·JournalCell Reports Medicine·TypeExperimental study·DateNov 16, 2021
A study of over 1,100 prostate cancer patients found that androgen deprivation therapy did not increase the risk of death within 30 days after a COVID-19 infection. Researchers concluded that men receiving androgen deprivation therapy had similar mortality rates as those who did not receive this treatment.
SourceJAMA Network·JournalJAMA Network Open·DateNov 12, 2021
A new study in mice found that PFAS exposure reprograms the metabolism of benign and malignant human prostate cells to a more energy efficient state. Consuming a high-fat diet significantly accelerated development of tumors in PFAS-exposed mice, suggesting a synergistic interaction between the two.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalNutrients·TypeExperimental study·DateNov 11, 2021
Researchers developed a blood test that can detect prostate cancer patients who are resistant to chemotherapy drug docetaxel, enabling early detection and personalized treatment. The test analyzes circulating tumor cells in the bloodstream, revealing patterns that predict disease progression and survival.
SourceNational Cancer Research Institute·TypeObservational study·DateNov 9, 2021
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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A study analyzing 93 precision oncology studies revealed significant underrepresentation of racial and ethnic minority populations in cancer research. These disparities affect the representation of diverse patient groups in clinical trials, which can impact treatment efficacy and outcomes.
SourceJAMA Network·JournalJAMA Network Open·DateNov 8, 2021
A recent study found that Black, Hispanic, and Asian men are less likely to receive an MRI exam after a prostate-specific antigen (PSA) blood test. The study suggests racial and ethnic disparities in the use of prostate MRIs following elevated PSA results.
SourceGeorgia Institute of Technology·JournalJAMA Network Open·TypeObservational study·DateNov 8, 2021
Researchers found that restoring NXTAR expression can suppress prostate tumor growth, suggesting a new approach to treating hormone-resistant prostate cancer. The study identified an RNA molecule called NXTAR that plays a key role in regulating the androgen receptor, a protein driving prostate tumor growth.
SourceWashU Medicine·JournalCancer Research·DateNov 5, 2021
A phase III clinical trial found that a trio of drugs, apalutamide, abiraterone, and prednisone, slowed the progression of metastatic castration-resistant prostate cancer by 24 months compared to 16.6 months with abiraterone and prednisone alone.
SourceUniversity of Montreal Hospital Research Centre (CRCHUM)·JournalThe Lancet Oncology·TypeRandomized controlled/clinical trial·DateNov 3, 2021
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A new pilot study reveals a prostate cancer urine test can identify men with intermediate-risk disease, allowing them to opt for active surveillance instead of immediate treatment. The test assesses the amount of aggressive cancer in the prostate without needing a biopsy.
SourceUniversity of East Anglia·JournalLife·TypeExperimental study·DateNov 2, 2021
Researchers found diet-associated molecules in the gut are associated with aggressive prostate cancer, linking them to higher levels of metabolites like phenylacetylglutamine and nutrients choline and betaine. The study's findings may have clinical implications for diagnosing and preventing lethal prostate cancer.
SourceCleveland Clinic·JournalCancer Epidemiology Biomarkers & Prevention·DateOct 28, 2021
A new international meta-analysis of randomized clinical trials found that adding androgen deprivation therapy (ADT) to definitive radiotherapy improves metastasis-free survival by 8% and overall survival by 7%. Prolonging adjuvant ADT for 18-36 months also shows similar benefits.
SourceUniversity of California - Los Angeles Health Sciences·TypeData/statistical analysis·DateOct 27, 2021
The NRG-RTOG 0815 trial found that adding androgen suppression to dose-escalated radiotherapy did not improve overall survival, but reduced rates of biochemical failure and distant metastases. Future studies are needed to identify subsets of patients who may benefit from this intervention.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A recent clinical trial found that a shortened course of radiation therapy after prostate removal surgery does not increase long-term side effects or lower quality of life compared to conventional treatment. Patients who underwent hypofractionated, post-operative radiation therapy experienced comparable genitourinary and gastrointestin...
SourceAmerican Society for Radiation Oncology·DateOct 25, 2021
A Phase III clinical trial found no significant increase in genitourinary or gastrointestinal toxicity with hypofractionated post-operative prostate bed radiotherapy compared to conventional radiotherapy. However, dose-escalated radiation therapy was not shown to be superior to conventional RT.
Scientists at Osaka University developed a novel system for targeted cancer radiation therapy using gold nanoparticles labeled with astatine-211. The nanoparticles are highly toxic to cancer cells while remaining localized, minimizing damage to healthy tissues.
SourceOsaka University·JournalJournal of Nanobiotechnology·TypeExperimental study·DateOct 19, 2021
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Research suggests that regular PSA testing from age 40 could detect life-threatening prostate cancer in men with genetic hallmarks of Lynch syndrome, increasing the chances of earlier diagnosis and treatment. Men with MSH2 gene faults were eight times more likely to be diagnosed with prostate cancer at a younger age.
SourceInstitute of Cancer Research·JournalThe Lancet Oncology·TypeExperimental study·DateOct 19, 2021
A new study found that common gut bacteria can drive prostate cancer growth and treatment resistance by providing an alternative source of growth-promoting androgens. Researchers identified specific bacterial 'fingerprints' linked to prostate cancer outcome, which could help identify men who could benefit from strategies to manipulate ...
SourceInstitute of Cancer Research·JournalScience·TypeExperimental study·DateOct 7, 2021
The ARAMIS phase III clinical trial found that darolutamide improved metastasis-free survival and overall survival in Black/African American patients. Darolutamide-treated patients had a higher three-year overall survival rate and longer time to disease progression compared to placebo-treated patients.
SourceAmerican Association for Cancer Research·DateOct 6, 2021
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A clinical trial found that obese prostate cancer patients who underwent regular exercise training for 12 weeks had increased levels of anti-cancer myokines, which suppressed tumour growth and helped fight cancerous cells. The study suggests exercise may be a key weapon in cancer patients' battle against the disease.
SourceEdith Cowan University·JournalMedicine & Science in Sports & Exercise·TypeRandomized controlled/clinical trial·DateOct 4, 2021
Researchers mapped cancer through protein interactions, revealing biomarkers and potential new treatments for breast and head and neck cancers. The study provides a new definition of biomarkers based on large, multi-protein complexes, offering a more precise way to explain mutation effects.
SourceUniversity of California - San Francisco·JournalScience·DateSep 30, 2021
Researchers identified two subtypes of metastatic prostate cancer that respond differently to hormone treatment. Luminal tumors responded better to testosterone-blocking treatments, while basal tumors did not benefit as much from this hormone treatment.
SourceUniversity of Wisconsin-Madison·JournalJAMA Oncology·TypeData/statistical analysis·DateSep 23, 2021
Novartis presents Phase III MONALEESA-2 study results demonstrating improved overall survival with Kisqali (ribociclib) in combination with letrozole. The analysis shows a statistically significant and clinically meaningful improvement in survival, with median OS of 63.9 months.
A novel combination of abiraterone acetate and prednisolone has been shown to prolong survival in patients with hormone/castration-sensitive prostate cancer. Studies PEACE-1 and STAMPEDE found that the addition of these drugs to standard therapy lengthened survival compared to standard therapy alone.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateSep 19, 2021
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A new study found that genome-wide association studies (GWAS) results from people with European ancestry can still be applied to predict breast and prostate cancer risk in diverse groups. However, the findings emphasize the need for more diverse participants in GWAS analyses to realize the full potential of polygenic risk scores.
SourcePLOS·JournalPLOS Genetics·TypeExperimental study·DateSep 16, 2021
Research finds prostate cancer risk among 9/11 responders is 24% higher, with highest risk among earliest responders. The study also reveals a shorter latency period from exposure to disease development compared to other studies.
SourceBMJ Group·JournalOccupational and Environmental Medicine·TypeObservational study·DateSep 10, 2021
A study analyzing 6,775 patients with low-risk prostate cancer found that cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment. The study also found that higher Gleason grade, PSA level, tumor stage, and number of positive biopsy cores are related to shorter conversion times.
SourceWolters Kluwer Health·JournalThe Journal of Urology·DateSep 10, 2021
Firefighters who worked at the World Trade Center site after 9/11 are 13% more likely to develop cancer, particularly prostate and thyroid cancer. They were also diagnosed at a younger age, on average, with early-stage disease. The exact cause of this increased risk is unclear.
SourceBMJ Group·JournalOccupational and Environmental Medicine·TypeObservational study·DateSep 10, 2021
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers identify molecular targets for improved prostate cancer therapy by comparing genomic changes in cancer cells eradicated and resistant to treatment. The study also finds L1 retrotransposition as a dynamic source of cancer heterogeneity.
SourceTampere University·JournalCancer Research·DateSep 10, 2021
Researchers at Tampere University identified a specific population of treatment-resistant cells that persists in prostate cancer tissue. This finding suggests that the presence of these cells can predict patient responses to treatment and may help tailor treatment for different subgroups of patients.
SourceTampere University·JournalNature Communications·DateSep 8, 2021
Researchers at Flinders University have identified a protein called 6PGD that supports the survival of prostate cancer cells when challenged with hormonal therapy. The study found that 6PGD inhibitors can kill cancer cells in lab dishes and real tumours, offering new hope for targeted therapies
SourceFlinders University·TypeObservational study·DateAug 26, 2021
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A population-based study found that nearly half of men with low-risk prostate cancer transitioned from active surveillance to definitive treatment within five years after diagnosis. The study, published in The Journal of Urology, analyzed data from 8,541 men and identified factors associated with the likelihood of transition, including...
SourceWolters Kluwer Health·JournalThe Journal of Urology·DateAug 20, 2021
Monash University researchers have established a vast collection of living prostate cancer tumors from patients, enabling the testing of new treatments and advancing patient care. The PDX collection comprises 59 tumors collected from 30 patients between 2012-2020, providing a unique resource for scientists and pharmaceutical companies.
SourceMonash University·JournalNature Communications·TypeExperimental study·DateAug 19, 2021
A recent study reveals that some prostate cancer survivors experience a persistent fear of cancer recurrence (FCR) even many years after diagnosis and treatment. The study identified patient and clinical risk factors linked with FCR, highlighting the need for ongoing monitoring and psychosocial care.
A recent study published in European Journal of Epidemiology reveals that widowers are at a higher risk of being diagnosed with advanced prostate cancer. The research highlights the importance of social environment and lifestyle factors in the development of the disease.
SourceInstitut national de la recherche scientifique - INRS·JournalEuropean Journal of Epidemiology·TypeMeta-analysis·DateAug 12, 2021
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A novel blood test, Stockholm3, can reduce the number of MRIs performed by a third while preventing the detection of minor, low-risk tumours. The addition of this test to MRI reduces overdiagnosis by as much as 69% and halves the number of biopsies.
SourceKarolinska Institutet·JournalThe Lancet Oncology·TypeRandomized controlled/clinical trial·DateAug 12, 2021
Researchers have found a way to harness the power of immunotherapy for advanced prostate cancer by targeting a protein called PIKfyve. Blocking PIKfyve with the inhibitor ESK981 has been shown to increase tumor death and recruit immune T cells, offering new hope for patients with this challenging form of cancer.
SourceMichigan Medicine - University of Michigan·JournalNature Cancer·TypeExperimental study·DateAug 2, 2021
The American Academy of Family Physicians is investigating an 'educational' session promoting dairy products linked to increased risk of prostate cancer and other diseases disproportionately affecting African Americans. The Physicians Committee for Responsible Medicine filed a complaint, citing standards set by the Accreditation Counci...
SourcePhysicians Committee for Responsible Medicine·DateJul 29, 2021
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A new genomic test may help identify patients at high risk of prostate cancer progression. The Decipher Biopsy test showed that men with high scores needed active treatment sooner, and those who underwent surgery had shorter time until PSA levels increased or they were put on anti-androgen therapy.
SourceMichigan Medicine - University of Michigan·JournalProstate Cancer and Prostatic Diseases·DateJul 27, 2021
A study of 647 patients with untreated nonmetastatic prostate cancer found that Black men underwent significantly fewer prostatectomies during the pandemic compared to white patients. Prior to the pandemic, there was no difference in treatment rates between the two groups.