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Fit for life: childhood fitness linked to lower risk of adult depression

A new study published in the Journal of Affective Disorders found that children and teenagers with better cardiorespiratory fitness had a lower risk of developing depression as adults. The research, which spanned over 30 years, examined the fitness of Australian children aged 7-15 and found that cardiorespiratory fitness was the strong...

SourceAdelaide University·JournalJournal of Affective Disorders·TypeCase study·DateSep 30, 2026

Prenatal exposure to depression linked to neurodevelopmental disorders

A new study found that children of mothers with depression have a higher risk of neurodevelopmental disorders, regardless of antidepressant exposure. The study followed over 167,000 children and found a significant association between maternal depression and special educational needs in children.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateSep 29, 2026

Fighting depression with humour. SWPS University study: Laughter can bring relief, but not any moment is right

A SWPS University study investigated the potential of using humour to treat depressive states, finding humour can improve mood and boost resilience, but not during acute phase, when it can worsen mood. The study highlights the importance of tailored humour interventions and caution when using humour with individuals with depression.

SourceSWPS University·JournalClinical Psychology Review·TypeSystematic review·DateSep 24, 2026

Nine studies led by Mount Sinai investigators featured in coordinated collection of papers that map the molecular and cellular architecture of brain disorders

Researchers identified shared and disease-specific molecular changes in human brain tissue, contributing to neurodegeneration, psychiatric illness, and cognitive decline. The collection establishes a foundational resource for understanding brain disorders, accelerating discovery and therapy development.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature·TypeObservational study·DateSep 23, 2026

Before psychosis strikes

Researchers at UCI are developing a countywide system of care to identify youth at risk of psychosis and connect them with support, with the goal of preventing first episodes. The four-year initiative aims to provide treatment and coordinated care to over 150 young people, with outreach to families, schools, and community organizations.

Researchers discover rare cortical neurons that can help put the brain to sleep

Researchers have discovered a rare population of neurons in the cortex that can synchronize activity across large areas of the brain and promote sleep. These Sst-Chodl neurons were found to be active during the transition to sleep and could even help drive the process, suggesting that the cortex is not simply passive during sleep.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature·TypeExperimental study·DateSep 11, 2026

New video game could help reveal how people with autism perceive the world

A new video game, Geode, measures how people with autism understand and interpret information, providing fresh insights into the autistic brain and refining therapy development. The game, which can be played by people across the autism spectrum, includes nonverbal players and was successful in collecting detailed data on sensory input ...

SourceBoston University·JournalScience Advances·TypeComputational simulation/modeling·DateSep 11, 2026

Mental health conditions after trauma linked to higher cardiovascular risk

Research suggests that mental health conditions, including PTSD, substance abuse, and depression, can increase the risk of future cardiovascular risks such as heart attacks, strokes, and cardiovascular death. Alcohol abuse was found to be the top psychiatric predictor of serious heart and brain conditions for both men and women.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateSep 2, 2026

Scientists uncover shared biology behind profound fatigue in five major illnesses

A new study reveals striking biological similarities between five major illnesses, including long Covid and PTSD, suggesting common underlying mechanisms. Chronic fatigue syndrome, rheumatoid arthritis, and multiple sclerosis may be driven by shared regulatory networks in immune and metabolic systems.

SourceUniversity of East Anglia·JournalJournal of Translational Medicine·TypeComputational simulation/modeling·DateSep 2, 2026

September 2026 issues of APA journals feature new research on treating substance use disorders, mood disorders, pediatric anxiety disorders, and more

The September 2026 issues of APA journals feature new research on treating substance use disorders, mood disorders, and pediatric anxiety disorders. Journal highlights include studies on the effects of parental social media use and the implementation of measurement-based care in mental health services.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateSep 1, 2026

Immune system and mental health

Researchers analyzed studies of schizophrenia spectrum disorders and mood disorders, finding distinct patterns of innate immune activity. TLR4, TLR8, and TLR10 were increased in schizophrenia, while TLR2, TLR5, and TLR6 were increased in mood disorders, indicating partially distinct mechanisms of innate immune activation.

SourceWroclaw Medical University·JournalBrain Behavior and Immunity·TypeSystematic review·DateAug 25, 2026

Severe mental illness linked to higher dementia risk even at young age, and greater stroke risk earlier in life

A large study found a significant association between severe mental illness and dementia at every age, with adults aged 30-39 showing a 20-fold increased risk of dementia. The study also found a higher risk of stroke in early and middle adulthood, particularly in those with severe mental illness.

SourceEuropean College of Neuropsychopharmacology·JournalEuropean Neuropsychopharmacology·TypeObservational study·DateAug 17, 2026

Patients with IBD face elevated risk of psychiatric disorders

Researchers found that patients with inflammatory bowel disease (IBD) are at a significantly higher risk of developing psychiatric disorders, particularly depression and anxiety. The study highlights the importance of early screening and integration of psychological care into routine IBD management to improve quality of life.

SourceAmerican Gastroenterological Association·JournalClinical Gastroenterology and Hepatology·DateAug 5, 2026

Two ways to read a genome: Scientists reveal the first body-wide, single-cell atlas that maps DNA folding and epigenetics together

Researchers at Salk Institute create a body-wide single-cell atlas of two major epigenetic systems, revealing that cell-type-specific epigenetic features can affect disease risk. The study identifies over 1.36 million differentially methylated regions and 283,606 differential chromatin loops across the human body's cell types.

SourceSalk Institute·JournalScience·DateJul 23, 2026

Imaging shows increased brain aging across different brain disorders

A study published in PLOS Medicine found that people with dementia, mild cognitive impairment, alcohol addiction, or psychiatric disorders like schizophrenia show increased brain aging patterns. The researchers analyzed MRI data from over 45,900 controls and compared them to 2,698 patients with different brain conditions.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 21, 2026

Weight loss drugs could help with binge eating disorder

A systematic review and meta-analysis found that weight loss drugs can reduce key symptoms of binge eating disorder, including binge eating episodes, loss-of-control eating, and emotional eating. The study suggests that these medications could be an important part of treatment plans for people with binge eating disorder.

SourceUniversity College London·JournalEClinicalMedicine·TypeMeta-analysis·DateJul 15, 2026

People with disabilities are diagnosed with alcohol use disorder at much higher rates than non-disabled people

A new study found that adults with disabilities have more than three times the rate of alcohol use disorder diagnoses compared to adults without disabilities in the US. Adults with serious mental illness and acquired brain injuries had the highest rates of AUD, with men with disabilities having the highest rates.

SourceBoston University School of Public Health·JournalDrug and Alcohol Dependence Reports·TypeObservational study·DateJul 14, 2026

Untangling the risk factors for developing multiple chronic conditions among UK South Asian populations

A study published in PLOS Medicine found that British Bangladeshi and British Pakistani individuals are more likely to develop multimorbidity, a condition where people experience multiple chronic illnesses simultaneously. The research identified sociodemographic and genetic factors that increase the risk of developing these conditions,...

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 9, 2026

ADHD and autism diagnoses have increased. New study points to broader diagnoses as an explanation

A new study from the University of Copenhagen found that people diagnosed with ADHD or autism in recent years have a lower genetic predisposition than those diagnosed earlier. The study suggests that today's diagnoses encompass a broader group of individuals and milder symptom profiles. This shift is attributed to changes in diagnostic...

SourceUniversity of Copenhagen·JournalJAMA Psychiatry·DateJul 1, 2026

Mapping the risk factors for mother-infant bonding disorder

Researchers at University of Toyama found three risk factors for mother-infant bonding disorders: difficulty holding a fussy baby, low happiness about pregnancy, and lack of social support. These factors predict increased risks of developmental delays and child abuse.

SourceToyama Regional Center for the Japan Environment and Children's Study, University of Toyama·JournalArchives of Women s Mental Health·TypeObservational study·DateJun 30, 2026

Vibrating pill could help predict relapse risk for anorexia nervosa patients

A new study found that individuals with anorexia nervosa may struggle to detect subtle stomach sensations and update their expectations when signals are present, which can lead to higher relapse risk. The vibrating pill could help doctors identify patients at higher risk of relapse and track treatment effectiveness.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Psychiatry·TypeRandomized controlled/clinical trial·DateJun 17, 2026

Can memory be predicted with a saliva test?

A study led by Raül Andero at the Universitat Autònoma de Barcelona found that the ratio of progesterone to estradiol hormones in saliva can predict memory performance, including fear extinction in both mice and humans. This hormonal balance may help identify optimal times for learning and memory tasks.

SourceUniversitat Autonoma de Barcelona·JournalNeurobiology of Stress·TypeExperimental study·DateJun 8, 2026