Articles tagged with Psychiatric Disorders
A Virginia Tech study found that female brains use a molecular process not seen in male brains to form fear memories. The researchers suggest that treatments for PTSD may need to be tailored differently for men and women. The discovery could lead to better understanding of PTSD and more effective treatments.
A nationwide analysis of Japanese citizens found that SGM individuals experience greater mental health distress, with no improvement seen from living in municipalities with partnership certification systems. Surprisingly, suicidal ideation was reported more frequently among those with such systems.
The FUTURE-D project combines data science with clinical expertise to identify warning signs of depression earlier, enabling more targeted interventions. Researchers will integrate longitudinal cohort data from the MACS and NESDA studies to better understand depressive disorders.
The project aims to expand University Hospitals' collaborative care model from 26 practices to all 88 practices within the UH Primary Care Institute. It will also broaden services to include screening and treatment for conditions such as bipolar disorder and post-traumatic stress disorder (PTSD).
Researchers developed a new reference model for the human brain using diffusion MRI scans from over 54,000 people. The model provides growth charts for white matter neural pathways, helping identify subtle changes linked to aging, Alzheimer's, schizophrenia risk and other neurological conditions.
Researchers at UCLA Health have identified a brain region called the ventromedial prefrontal cortex (vmPFC) that regulates memory integration. The vmPFC acts as a quality control checkpoint, preventing memories from getting mixed up when they are significantly different or far apart in time.
A new study by the Child Mind Institute found that more than one in four youth with mental health and neurodevelopmental concerns experienced negative online experiences, including cyberbullying and harassment. Despite this, only 20% of these incidents were reported through platform tools.
Patients who received five minutes of in-person prayer experienced greater relief from both pain and anxiety compared to those who listened to music. The study found significant improvements in pain reduction at two weeks, with black participants showing larger improvements.
The study found that mental disorders disproportionately affect young people aged 15-19 and women, with anxiety and depression ranking among the top causes of disability globally. Mental disorders now account for 171 million DALYs, placing them as the fifth-leading cause of total disease burden worldwide.
Researchers have identified blood-based proteomic biomarkers that may help predict the development of psychosis in at-risk Asian youths. The study, which used data from the Longitudinal Youth at Risk Study (LYRIKS), found that models developed using the LYRIKS dataset performed better than those based on Caucasian protein patterns.
New research finds that low-dose buprenorphine given after a single ketamine infusion can sustain reductions in suicidal ideation in adults with major depressive disorder. The study showed a 76% reduction in suicidal ideation at week four, compared to a 43% reduction in the placebo group.
A new study led by Murdoch University found that children of parents with severe mental illness are more likely to experience cognitive difficulties. The study analysed data from over 1.5 million people and found that offspring tended to perform lower across several cognitive domains, particularly where a parent had schizophrenia or bi...
A major new study has found that severe asthma patients are often battling other health conditions, with nearly all suffering from at least one major issue. The study identified three distinct profiles linked to how well asthma is controlled and the treatments needed, offering potential breakthroughs for improving care.
A new study by the University of East Anglia reveals that refugees who entered the UK as unaccompanied minors experience relentless cycles of intrusive memories, loneliness, and physical pain. Social connection emerges as a powerful buffer against distress, with many participants finding comfort in activities like cricket or prayer.
A new study finds that individuals with higher resilience tend to place greater weight on positive aspects in cost-benefit decisions, a process mediated by brain activity. This regulated handling of negative information is linked to increased acceptance and improved psychological resilience.
A new study has mapped the histamine system in the brain, revealing its role in regulating emotions, stress, and decision-making. The findings provide a framework for understanding how histamine contributes to brain function and could point towards new treatment strategies for histamine-related conditions.
A study published in Cell Reports Medicine reveals that traumatic experiences during critical periods of life, particularly childhood to early adulthood, have lasting impacts on brain development and behavior. The research found that the timing of trauma, not its type, plays a key role in determining distinct behavioral outcomes.
Researchers found that individuals with stronger brain responses to negative information were more resilient in their thoughts and feelings. They accepted more offers with mixed consequences, indicating a lower value on negative outcomes. This study suggests that controlling negative thoughts may enable people to build mental resilience.
Two studies by Rutgers University professor Colleen Berryessa explore how expressions of remorse are interpreted in the legal system, finding that it can lead to serious inequities in legal outcomes. The research highlights the need for greater awareness and education within the legal system to better understand how remorse is assessed.
A nationwide cohort study found a bidirectional association between premenstrual disorders and psychiatric disorders, highlighting the need for sex- and menstrual cycle–informed care in psychiatry. The study's findings emphasize the importance of considering menstrual cycles when diagnosing and treating psychiatric conditions.
A Charité study analyzed therapist experiences worldwide to create a profile for successful psychedelic-assisted therapy. Key characteristics include stable environment, support from loved ones, and specific personality traits that contribute to treatment success.
A new study with over 3,700 UK participants found that better cognitive functioning may be associated with a higher risk of future depressive episodes in those with a history of depression. In contrast, worse cognitive performance was linked to a lower risk of relapse in both individuals with previous depression and control participants.
A randomized clinical trial found that genotype-guided prescribing of SSRIs did not improve depression symptoms at 3 months but showed higher remission rates at 6 months. Future studies should focus on the long-term impact of this approach.
A study finds microplastics in the human brain associated with increased risk of stroke and dementia. Apheresis, a medical treatment, is proposed as a potential removal method for microplastics from the body.
Gonçalo Cotovio uses lesion network mapping to identify the circuits responsible for psychiatric symptoms, aiming to develop personalized brain stimulation treatments. His work has produced striking findings in mania and obsessive-compulsive disorder, with ambitions to extend to disordered feeding behavior.
Dr. Dilek Colak's journey began with a childhood observation of a boy with mental illness, which inspired her to pursue a career in neuroscience. Her current work focuses on understanding autism and schizophrenia through the study of human brain organoids.
A study by Kelsie Forbush and colleagues used Hierarchical Taxonomy of Psychopathology to better understand how psychological conditions like depression, anxiety, and post-traumatic stress disorder are connected. The findings suggest that HiTOP's symptom dimensions may support more precise, personalized mental health care.
Researchers found that accelerated biological aging of a type of white blood cell called monocytes is linked to cognitive and mood-related symptoms of depression. This discovery could lead to earlier diagnosis and personalized treatment for depression, particularly in high-risk populations such as women with HIV.
A 20-year follow-up study by the University of Copenhagen reveals that nearly all patients who initially admitted to hospital psychiatry returned, with significant consequences on their education, family life, and health. The researchers emphasize the importance of early and comprehensive assessments to provide better support and preve...
The American Medical Association (AMA) has developed guidelines for treating anxiety disorders in adults in primary care settings. Behavioral therapy, including cognitive-behavioral therapy (CBT), and medication, such as selective serotonin reuptake inhibitors (SSRIs), are recommended treatments.
The latest issues of APA journals feature new research on PTSD and substance use disorders. The American Journal of Psychiatry explores the understanding of these conditions, while Psychiatric Services discusses the future of the DSM. Focus journal delves into psychopharmacologic treatments with expert perspectives.
A study by SWPS University found that people with depressive symptoms use less active language, such as 'I am incapable' instead of 'I achieve goals'. This analysis of social media posts shows promise for early detection and prevention of depression.
A large South Korean study found no increased risk of psychiatric or neurodevelopmental disorders in children whose mothers used sedative drugs during pregnancy. The study, published by the BMJ Group, tracked nearly 3.8 million children and analyzed data from the National Health Information Database.
A scalable digital mental health care model and anti-stigma campaigns reduced depression, self-harm, and suicide risks among Indian adolescents. The ARTEMIS project reached over 70,000 adolescents and showed significant improvements in knowledge, attitude, and behavior toward mental health.
A nationwide ecological study found a statistical correlation between fewer psychiatric beds and higher suicide rates in Sweden. The study suggests that investing in outpatient care may not be enough to prevent suicides, highlighting the need for further research into healthcare resource allocation.
Researchers analyze brain imaging data, microbiome profiles, and clinical assessments to identify biomarkers for precision mental healthcare. Early findings suggest certain electroencephalography features serve as non-invasive biomarkers indicating disease severity and treatment response.
Researchers developed an AI tool that analyzes routine electronic health records to predict ADHD risk in children years before a typical diagnosis. The model accurately identified risk in children age 5 and older, with consistent performance across patient characteristics.
tACS modulates brain oscillations, induces synaptic plasticity, and regulates neurotransmitter release to alleviate symptoms of various neuropsychiatric conditions. Personalized approaches are essential for treatment efficacy.
A Swedish study of siblings found that adopted children who grew up in more favourable family environments had lower risks of mental health issues, criminality, and social problems. These benefits extended to the next generation, with adopted children's offspring displaying higher functioning and lower risks.
A retrospective cross-sectional study found significant associations between unsecured firearm storage and heightened suicide risk in US Army service members. Carrying a weapon other than a firearm also linked to elevated suicide risk, suggesting that any type of weapon carrying behavior may indicate increased vulnerability.
A longitudinal study of 156 Ukrainian amputees found that most experience steady improvements in pain, anxiety, and depression over time. The study revealed distinct patterns of post-amputation pain, with phantom limb pain linked to psychological distress and residual limb pain linked to depression.
Research found that gender-diverse teens reported higher rates of psychological stress and psychotic-like experiences, which can lead to depression, anxiety, and other serious mental health disorders. Bullying and unsupportive legislation drove these findings.
A new study found that brain activity and emotional reactivity may predict risk of readmission for patients with major depressive disorder or bipolar disorder. Participants who reacted strongly to negative emotions were at higher risk of hospitalization, suggesting a potential biomarker for identifying vulnerable individuals.
A large clinical trial found that magnetic seizure therapy is as effective as electroconvulsive therapy in improving depressive symptoms, with fewer cognitive side effects. The therapy could become a new standard option for people with severe depression.
Researchers develop molecular tool called SynTrogo, which enables selective dismantling of synaptic connections in brain circuits. By harnessing astrocytes, the system reduces synapse number while strengthening remaining connections, leading to enhanced long-term potentiation and improved memory.
A study of 1,001 people in England found that calorie labels on restaurant menus can be helpful for those with binge eating disorders, particularly those who feel a sense of control over their eating. In contrast, individuals with restrictive eating disorders viewed them negatively.
Researchers from UMBC discover that inputs from the dorsal and ventral hippocampus interact closely on the same neurons in the nucleus accumbens, integrating memories of places and contexts with drive to pursue rewards. This convergence may help animals form associations between rewarding outcomes and environments, essential for survival.
A recent genetic study analyzing DNA from 2 million people found that similar chunks of DNA are associated with both psychiatric disorders like depression and PTSD, as well as various physical ailments. This discovery could lead to more effective treatments that address both mental and physical health.
A new study from the University of Southern Denmark finds that people with depression experience significant income loss, with losses averaging 17% lower than those without depression. Income loss persists and grows over time, even after diagnosis.
The University of Houston is strengthening its behavioral health programs with a $1.6 million gift from IntraCare North Hospital, supporting social work and nursing scholarships. This investment addresses Texas' critical shortage of mental health professionals, enabling the next generation of experts to serve communities in need.
The latest issues of APA journals publish new research on cannabis use disorder, stigma reduction interventions, and co-occurring psychiatric and substance use disorders. Highlights include studies on depression-related stigma among Black and Latinx youths and the impact of text engagement in a brief technology-enhanced intervention.
Researchers have demonstrated that noninvasive brain stimulation can alter the activity of the hippocampus, a critical deep brain region involved in emotion and memory. Personalizing the stimulation site using a patient's unique brain connectivity pathway increases the neuromodulation effect.
A study on mice suggests that adolescence stress causes permanent changes in the prefrontal cortex, increasing vulnerability to schizophrenia and depression. The researchers found that traumatic experiences during this stage of life disrupts communication between brain cells, compromising neural control.
A study published in Brain Medicine suggests autonomic dysfunction, particularly parasympathetic and sympathetic imbalances, contributes to depressive symptoms in patients unresponsive to conventional antidepressants. Low-dose medications targeting these imbalances may offer a new approach to treatment.
A binational study found most psychotherapists lack adequate knowledge and confidence treating eating disorders and muscle dysmorphia in boys and men. Clinicians identified a need for specialized training on assessing unique risk factors, tailoring treatment to male-specific experiences, and addressing stigma.
Researchers found a direct line of communication between the brain's stress centers and decision-making regions, which is disrupted by alcohol. This disruption can lead to unhealthy habits and relapse during recovery from alcohol use disorder.
Researchers identified NOX-1 as a key molecular target to prolong ketamine's therapeutic benefits. Combining ketamine with NOX-1 inhibitors significantly extended its antidepressant-like effects. K-4, a novel AMPAR modulator, also showed rapid antidepressant effects that persisted for at least 2 weeks.
A study estimated income losses from individual perspectives in Denmark from 2000 to 2023 after hospital diagnoses of depression, alcohol use disorder, stroke, and breast cancer. The researchers found that income losses were largest for mental disorders, with average losses growing over time, particularly among younger individuals.
A Finnish registry study found that severe infections, such as cystitis and bacterial disease, are associated with an increased risk of dementia. The study examined nationwide health registry data and identified 29 diseases linked to dementia risk, including mental disorders, Parkinson's disease, and alcohol-related mental disorders.
A new study reveals US and UK volunteer fighters in Ukraine experience high levels of mental and physical health difficulties, including PTSD, moral injury, and poor quality of life. Many struggle to access healthcare after deployment, instead relying on fellow volunteers for support.