Articles tagged with Psychiatric Disorders
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Researchers at the University of Rochester have developed a new mouse model that mimics symptoms of myotonic dystrophy, allowing for potential treatments to be tested. The mice provide insight into the disease-causing role of mRNA and its impact on muscle fibers.
A team of researchers has discovered the gene responsible for Mucolipidosis IV, a rare genetic disorder affecting Ashkenazi Jews. The newly identified gene is linked to impaired fat breakdown, leading to accumulation of fats and sugars in lysosomes.
Researchers found that 19 out of 47 people with mild cognitive impairment who had difficulty identifying smells went on to develop Alzheimer's disease. The study suggests that the inability to recognize smells, combined with a lack of awareness about impaired olfactory senses, may be used as a predictor of impending Alzheimer's disease.
New research found that demographic characteristics associated with improved mental health in cardiac disease patients are not good for their physical recovery. However, being female and having less social support were linked to better physical component scores.
Researchers at Jefferson Medical College successfully introduced a therapeutic gene into the brain of two children with Canavan disease, showing decreased NAA concentration and increased myelin. The gene transfer demonstrated positive neurological improvements in the patients, offering hope for future use of gene therapy for brain dise...
A study by Case Western Reserve University found that people with higher levels of non-occupational activities were less likely to develop Alzheimer's disease later in life. Intellectual and physical activities, such as playing musical instruments or exercising, may help ward off the disease.
Experts examine parasitic and infectious diseases that can be spread by animals to people, highlighting the importance of integrated perspectives on human-animal interaction. The symposium aims to create a forum for discussing public health and food safety issues related to animal-human relationships.
Researchers use MRI and magnetic resonance spectroscopy to detect Alzheimer's disease by measuring chemical markers in the brain. The study found that this technique can distinguish patients with Alzheimer's from those without the disease and identify patterns of damage consistent with the disease.
A national study found that women aged 40+ are less active due to lack of social support, caregiving duties, and inconvenient environments. The majority prefer exercising alone with instruction over group sessions.
Researchers at UT Southwestern Medical Center have developed an easy and inexpensive index to measure the severity of Alzheimer's disease. The index correlates a simple lab test determining platelet Alzheimer's plaque protein (APP) in blood with cognitive decline, as measured by the Mini-Mental State Exam.
A door-to-door campaign in Auckland, New Zealand raised awareness of meningococcal disease among at-risk populations. The campaign, initiated in 1998, used lay educators to visit over 11,000 homes and deliver key messages about the disease.
Research found that psychologically abused women experienced higher rates of disability, chronic pain, and other physical health issues compared to non-abused women. The study also highlighted the need for effective clinical- and community-based interventions to address intimate partner violence in women's lives.
A study by the American Academy of Neurology found that people with higher levels of non-occupational activities, such as playing a musical instrument or gardening, were less likely to develop Alzheimer's disease later in life. Researchers also discovered that it is never too late to get started with intellectual activities.
Two studies found that large managed behavioral health organizations deny fewer treatment services than previously thought, while also reducing costs. The private sector outperformed VA hospitals on most quality measures, but the VA treats a more troubled population and has improved over time.
A new study suggests Reminyl, a treatment for Alzheimer's disease, provides significant cognitive and functional improvements in patients. The medication has been shown to delay the emergence of behavioral symptoms and maintain daily functioning for up to a year.
The TMJ Association has launched a national awareness campaign to raise awareness about jaw joint diseases, which affect over 10 million Americans, mostly women. The campaign aims to promote quality research and improved treatments for the condition, which causes debilitating pain and dysfunction.
Hopkins researchers identified a dysfunction in HD that affects brain movement correction, leading to jerky movements. The study suggests that subtle jerkiness may appear before clinical symptoms, potentially providing an early diagnostic tool.
A study by Michigan State University found that one-quarter of respondents were unsure if their health plan included mental health services, while 43% equated mental health benefits to general medical services. The authors recommend increasing attention to mental health issues in primary care education.
A Yale study found that patients with mental illnesses are significantly less likely to undergo cardiovascular procedures, including angioplasty and coronary bypass surgery, compared to those without mental disorders. This disparity was not explained by the severity of cardiac illness or regional differences.
A new study of 663 children with elevated cholesterol levels found no adverse psychological effects after three years on a cholesterol-lowering diet. The Dietary Intervention Study in Children (DISC) looked at the effect and safety of a low-fat diet, and showed that it is safe for children with high blood cholesterol.
A new study by Canadian scientists found that highly stressed patients with ischemic heart disease do not respond as well to medications for their condition. Higher levels of stress resulted in lower effectiveness of treatment, with more highly stressed patients experiencing a greater reduction in episodes of angina.
A recent study found that leisure physical activity buffers the effects of minor stress, but aerobic fitness does not. This suggests that exercise may help minimize stress-related symptoms by distracting from stressors or instilling a sense of accomplishment.
The American Psychiatric Association's 1999 Fall Components Meeting tackled significant psychiatric topics such as Psychiatric Aspects on Violence, Psychiatric Dimensions of Disasters, and Addiction Psychiatry. The meeting brought together over 1,000 leading psychiatric experts to discuss these critical issues.
A recent study by Carnegie Mellon University researchers found that patients with a positive outlook and strong sense of control over their lives are less likely to experience a second coronary event. Those with low self-esteem, optimism, and feelings of control were two and a half times more likely to suffer from restenosis.
Research finds that revival in AIDS patients brings new uncertainties, affecting feelings of hope and future orientation, social roles and identities, interpersonal relationships, and changes in quality of life.
A new study found that women at high risk for breast cancer who are also anxious and lack self-control are less likely to get a mammogram. Researchers suggest problem-solving training may help address this issue among the most distressed women.
A new study suggests that hope plays a vital role in maintaining the health of HIV-positive men who have lost a loved one to AIDS. The researchers found that optimistic expectations and feelings of control over the disease are associated with a slower rate of progression of HIV-related illness.
A team of scientists has found a critical interaction between two brain proteins that could help explain the death of nerve cells in Alzheimer's disease. The discovery reveals that normal APP provides a protective function against cell death, while mutant forms do not.
Researchers found elevated TGase activity in postmortem brain tissue of HD patients, linking it to htt aggregation and nuclear inclusion formation. This novel finding appears to counter previous findings on amyloid protein deposits and the 'protein zipper' hypothesis.
Researchers describe the first case of sporadic fatal insomnia (SFI), a neurologic disorder matching Shakespeare's witches' curse, caused by protein misfolding rather than a mutant gene. The condition's symptoms and neuropathology are identical to those of fatal familial insomnia.
Researchers have discovered naturally occurring enzymes that can detoxify porphyrins, building blocks of haemoglobin, in a potential breakthrough for treating variegate porphyria. This rare disorder was passed down through the royal family, including Queen Elizabeth II's first cousin Prince William of Gloucester.
A UCSF study reports that melanoma patients with cancer spread to their sentinel lymph nodes have a greater chance of experiencing disease recurrence and mortality. The study found that patients with negative SLN biopsies had lower rates of disease recurrence and mortality.
A recent clinical trial found that fetal dopamine cell implants improved movement control in younger Parkinson's patients, but had no significant impact on older patients or daily activities. PET brain scans revealed increased dopamine activity in those who received the implants, but also showed more severe adverse experiences.
The new book Psychiatry and the Cinema explores how movie portrayals of psychiatrists have shaped public perceptions of mental health. By analyzing film representations of psychiatric treatment, the authors shed light on the intersection of entertainment and medicine.
Researchers found that changes in the brain characteristic of Alzheimer's disease begin years before clinical symptoms like memory loss. The study used brain tissue from over 60 subjects, including healthy individuals and those with dementia, to identify amyloid plaques and neurofibrillary tangles.
A German study suggests that people complaining of health problems related to dental amalgam fillings may be using it as a scapegoat for underlying psychological issues. The researchers found low levels of mercury in the saliva, blood, and urine of participants, contradicting concerns about the alloy's safety.
Research shows that caregivers with Alzheimer's disease are more likely to develop a high metabolic syndrome level, which increases the risk of heart attack and other health complications. Interventions such as exercise, psychological uplifts, and improved diet may help reduce stress and mitigate this risk.
A study of 206 patients with Alzheimer's disease found that those with the lowest genetic risk had fathers who were significantly older at birth. This suggests a possible link between paternal age and increased susceptibility to the disease, which could be influenced by environmental factors affecting the father's DNA.
A study by Johns Hopkins School of Public Health found that one APOE variant can predict the age of onset for Alzheimer's disease in those predisposed. The research suggests that lifestyle choices may be protective against the disease.
Researchers have discovered a new gene mutation associated with late-onset Alzheimer's disease, which interacts with other Alzheimer's genes and proteins. The A2M protein plays a crucial role in breaking down toxic amyloid plaques, suggesting a potential target for drug development to prevent or treat the disease.
Researchers found that identical twins are twice as likely to share nightmare frequency as nonidentical twins, with a 45% chance of one twin experiencing frequent nightmares if the other does.
A new study from Penn State found that families with patients in the early stages of Alzheimer's disease are more likely to accept available treatment, whereas those with advanced-stage patients may choose to withhold care. The study also highlighted the need for family involvement in making treatment decisions.
A new study found that social disruption in monkeys infected with simian AIDS virus accelerates disease progression. Monkeys separated from familiar companions experienced faster development of AIDS, highlighting the impact of psychosocial factors on immunodeficiency disease.
A new Alzheimer's disease treatment, metrifonate, has been shown to improve behavioral disturbances and mental performance in patients with mild-to-moderate dementia. The study found that metrifonate slowed the mental decline associated with Alzheimer's disease over a six-month period.
Researchers have discovered an imaging agent called Altropane that visualizes nerve loss in Parkinson's patients, providing a faster and cheaper alternative to existing methods. The study suggests that Altropane can help identify presymptomatic patients for experimental treatments and track disease progression.
A study found that family coordinators significantly improved asthma management in Latino and African-American families. The coordinators guided the families through four phases of self-regulation, increasing their knowledge and compliance with prescribed therapy.
Researchers at Washington University in St. Louis studied 82 healthy adults aged 64-83 over 12 years, finding that most remained stable and only 40% developed cognitive deterioration. The study's key findings suggest that subtle changes in performance can signal the onset of Alzheimer's disease, potentially leading to early intervention.
Researchers have made significant progress in understanding the effects of gender, age, hormones, and other factors on heart disease. A promising new diagnostic tool, dobutamine stress echocardiography, is being tested for its accuracy in detecting coronary artery dysfunction in women.
The article discusses psychiatric genetics research funded by Nazi Germany, raising concerns about the separation of science from the scientist. Dr. Miron Baron examines the history of this research and its implications for contemporary investigators.
Researchers found that even mild forms of Alzheimer's can be distinguished from normal aging-related memory changes. The brains of patients with even mild Alzheimer's were found to have amyloid plaques, indicating early disease onset.
Researchers at the Max Planck Institute of Neurobiology have rediscovered brain sections of Auguste D., a 51-year-old woman with early-onset Alzheimer's disease. The analysis confirmed the presence of neurofibrillary tangles and amyloid plaques, consistent with today's understanding of the disease.
Researchers found a genetic link between bleomycin hydrolase and Alzheimer's disease, with individuals having two copies of the G allele being four times more likely to develop AD. This discovery offers new opportunities for early intervention and potential therapy targeting this enzyme.
A recent study found that films featuring people with disabilities have increased in popularity, but often depict unrealistic scenarios, such as psychiatric disorders being linked to violence. Despite this, the study suggests that these portrayals can be used as a tool for promoting critical viewing skills and understanding of people w...
Researchers found that combining the Apolipoprotein E (ApoE) genetic test with clinical examinations significantly improved diagnosis accuracy for Alzheimer's disease. The study showed a 45% to 16% reduction in false positive diagnoses, emphasizing the potential of ApoE testing as a diagnostic aid.
Researchers have discovered a new genetic variation that increases the risk of developing Alzheimer's disease. The study found that changes in the APOE gene can lead to higher levels of beta-amyloid, contributing to the development of senile plaques in the brain.
Researchers found increased levels of butyrylcholinesterase (BChE) in brains with compact and insoluble beta-amyloid plaques, a hallmark of Alzheimer's disease. BChE may play a role in transforming benign amyloid protein deposits into the disease-causing plaques.
A study of 65 patients found that those with the Alzheimer's-related gene apoliprotein E-4 (APOE-4) are more susceptible to mental impairment after open heart surgery. The researchers believe this is due to the variant gene's inability to repair nerve cells efficiently.
Research data suggest limited benefits from screening programs, with significant costs incurred for low yields. The authors recommend improving the process by focusing on diseases prevalent in the country of origin, assessing disease prevalence, and providing education and counseling to migrants.
Researchers have discovered cellular and biochemical mechanisms that could lead to the development of new drugs to prevent or treat Huntington's disease. The study identifies neuronal intranuclear inclusions as aggregates of huntingtin protein, which interacts with brain cells.
A study published in The American Journal of Psychiatry found that brain activity in individuals with Down's syndrome can predict Alzheimer's-like dementia, offering new hope for early detection and intervention. Researchers used PET scans to measure brain activity while subjects were at rest or stimulated by visual stimulation.