Articles tagged with Psychiatric Disorders
A new study found that women at high risk for breast cancer who are also anxious and lack self-control are less likely to get a mammogram. Researchers suggest problem-solving training may help address this issue among the most distressed women.
A new study suggests that hope plays a vital role in maintaining the health of HIV-positive men who have lost a loved one to AIDS. The researchers found that optimistic expectations and feelings of control over the disease are associated with a slower rate of progression of HIV-related illness.
A team of scientists has found a critical interaction between two brain proteins that could help explain the death of nerve cells in Alzheimer's disease. The discovery reveals that normal APP provides a protective function against cell death, while mutant forms do not.
Researchers found elevated TGase activity in postmortem brain tissue of HD patients, linking it to htt aggregation and nuclear inclusion formation. This novel finding appears to counter previous findings on amyloid protein deposits and the 'protein zipper' hypothesis.
Researchers describe the first case of sporadic fatal insomnia (SFI), a neurologic disorder matching Shakespeare's witches' curse, caused by protein misfolding rather than a mutant gene. The condition's symptoms and neuropathology are identical to those of fatal familial insomnia.
Researchers have discovered naturally occurring enzymes that can detoxify porphyrins, building blocks of haemoglobin, in a potential breakthrough for treating variegate porphyria. This rare disorder was passed down through the royal family, including Queen Elizabeth II's first cousin Prince William of Gloucester.
A UCSF study reports that melanoma patients with cancer spread to their sentinel lymph nodes have a greater chance of experiencing disease recurrence and mortality. The study found that patients with negative SLN biopsies had lower rates of disease recurrence and mortality.
A recent clinical trial found that fetal dopamine cell implants improved movement control in younger Parkinson's patients, but had no significant impact on older patients or daily activities. PET brain scans revealed increased dopamine activity in those who received the implants, but also showed more severe adverse experiences.
The new book Psychiatry and the Cinema explores how movie portrayals of psychiatrists have shaped public perceptions of mental health. By analyzing film representations of psychiatric treatment, the authors shed light on the intersection of entertainment and medicine.
Researchers found that changes in the brain characteristic of Alzheimer's disease begin years before clinical symptoms like memory loss. The study used brain tissue from over 60 subjects, including healthy individuals and those with dementia, to identify amyloid plaques and neurofibrillary tangles.
A German study suggests that people complaining of health problems related to dental amalgam fillings may be using it as a scapegoat for underlying psychological issues. The researchers found low levels of mercury in the saliva, blood, and urine of participants, contradicting concerns about the alloy's safety.
Research shows that caregivers with Alzheimer's disease are more likely to develop a high metabolic syndrome level, which increases the risk of heart attack and other health complications. Interventions such as exercise, psychological uplifts, and improved diet may help reduce stress and mitigate this risk.
A study of 206 patients with Alzheimer's disease found that those with the lowest genetic risk had fathers who were significantly older at birth. This suggests a possible link between paternal age and increased susceptibility to the disease, which could be influenced by environmental factors affecting the father's DNA.
A study by Johns Hopkins School of Public Health found that one APOE variant can predict the age of onset for Alzheimer's disease in those predisposed. The research suggests that lifestyle choices may be protective against the disease.
Researchers have discovered a new gene mutation associated with late-onset Alzheimer's disease, which interacts with other Alzheimer's genes and proteins. The A2M protein plays a crucial role in breaking down toxic amyloid plaques, suggesting a potential target for drug development to prevent or treat the disease.
Researchers found that identical twins are twice as likely to share nightmare frequency as nonidentical twins, with a 45% chance of one twin experiencing frequent nightmares if the other does.
A new study from Penn State found that families with patients in the early stages of Alzheimer's disease are more likely to accept available treatment, whereas those with advanced-stage patients may choose to withhold care. The study also highlighted the need for family involvement in making treatment decisions.
A new study found that social disruption in monkeys infected with simian AIDS virus accelerates disease progression. Monkeys separated from familiar companions experienced faster development of AIDS, highlighting the impact of psychosocial factors on immunodeficiency disease.
A new Alzheimer's disease treatment, metrifonate, has been shown to improve behavioral disturbances and mental performance in patients with mild-to-moderate dementia. The study found that metrifonate slowed the mental decline associated with Alzheimer's disease over a six-month period.
Researchers have discovered an imaging agent called Altropane that visualizes nerve loss in Parkinson's patients, providing a faster and cheaper alternative to existing methods. The study suggests that Altropane can help identify presymptomatic patients for experimental treatments and track disease progression.
A study found that family coordinators significantly improved asthma management in Latino and African-American families. The coordinators guided the families through four phases of self-regulation, increasing their knowledge and compliance with prescribed therapy.
Researchers at Washington University in St. Louis studied 82 healthy adults aged 64-83 over 12 years, finding that most remained stable and only 40% developed cognitive deterioration. The study's key findings suggest that subtle changes in performance can signal the onset of Alzheimer's disease, potentially leading to early intervention.
Researchers have made significant progress in understanding the effects of gender, age, hormones, and other factors on heart disease. A promising new diagnostic tool, dobutamine stress echocardiography, is being tested for its accuracy in detecting coronary artery dysfunction in women.
The article discusses psychiatric genetics research funded by Nazi Germany, raising concerns about the separation of science from the scientist. Dr. Miron Baron examines the history of this research and its implications for contemporary investigators.
Researchers found that even mild forms of Alzheimer's can be distinguished from normal aging-related memory changes. The brains of patients with even mild Alzheimer's were found to have amyloid plaques, indicating early disease onset.
Researchers at the Max Planck Institute of Neurobiology have rediscovered brain sections of Auguste D., a 51-year-old woman with early-onset Alzheimer's disease. The analysis confirmed the presence of neurofibrillary tangles and amyloid plaques, consistent with today's understanding of the disease.
Researchers found a genetic link between bleomycin hydrolase and Alzheimer's disease, with individuals having two copies of the G allele being four times more likely to develop AD. This discovery offers new opportunities for early intervention and potential therapy targeting this enzyme.
A recent study found that films featuring people with disabilities have increased in popularity, but often depict unrealistic scenarios, such as psychiatric disorders being linked to violence. Despite this, the study suggests that these portrayals can be used as a tool for promoting critical viewing skills and understanding of people w...
Researchers found that combining the Apolipoprotein E (ApoE) genetic test with clinical examinations significantly improved diagnosis accuracy for Alzheimer's disease. The study showed a 45% to 16% reduction in false positive diagnoses, emphasizing the potential of ApoE testing as a diagnostic aid.
Researchers have discovered a new genetic variation that increases the risk of developing Alzheimer's disease. The study found that changes in the APOE gene can lead to higher levels of beta-amyloid, contributing to the development of senile plaques in the brain.
Researchers found increased levels of butyrylcholinesterase (BChE) in brains with compact and insoluble beta-amyloid plaques, a hallmark of Alzheimer's disease. BChE may play a role in transforming benign amyloid protein deposits into the disease-causing plaques.
A study of 65 patients found that those with the Alzheimer's-related gene apoliprotein E-4 (APOE-4) are more susceptible to mental impairment after open heart surgery. The researchers believe this is due to the variant gene's inability to repair nerve cells efficiently.
Research data suggest limited benefits from screening programs, with significant costs incurred for low yields. The authors recommend improving the process by focusing on diseases prevalent in the country of origin, assessing disease prevalence, and providing education and counseling to migrants.
Researchers have discovered cellular and biochemical mechanisms that could lead to the development of new drugs to prevent or treat Huntington's disease. The study identifies neuronal intranuclear inclusions as aggregates of huntingtin protein, which interacts with brain cells.
A study published in The American Journal of Psychiatry found that brain activity in individuals with Down's syndrome can predict Alzheimer's-like dementia, offering new hope for early detection and intervention. Researchers used PET scans to measure brain activity while subjects were at rest or stimulated by visual stimulation.
Researchers discovered a way to disrupt the aggregation of proteins that form poisonous plaque deposits in Alzheimer's patients. By synthesizing specific inhibitor molecules, they successfully blocked the toxicity of beta amyloid proteins, potentially leading to new treatments for the devastating disease.
Researchers at Stanford University have identified two separate clusters of neurons in the hippocampus involved in encoding and retrieving memories. These findings provide insight into the neural basis of memory and could lead to better treatments for Alzheimer's disease and other neurological disorders.
A transgenic mouse model of Huntington's disease has been developed, exhibiting symptoms resembling chorea and epileptic seizures. The R-6 strain is the first known mouse model to display these characteristics, allowing researchers to study the disease's progression.
Scientists have isolated and cloned the gene responsible for Fanconi anemia (FA), a rare disorder causing severe bone marrow failure, birth defects, and leukemia. The discovery enables the development of a quick diagnostic test for 65% of FA patients and may lead to better treatments, including gene therapy.