Articles tagged with Stomach Cancer
A new investigation into Napoleon's cause of death reveals that he died of a very advanced case of gastric cancer stemming from an ulcer-causing bacterial infection. The analysis suggests that gastrointestinal bleeding was the likely immediate cause of death and points to a poor prognosis for patients with such advanced cancer.
A new study of over 7,000 Japanese-American men found that those from large families were more than twice as likely to develop stomach cancer due to the bacterium Helicobacter pylori. Younger siblings in these families appeared especially vulnerable to the most common type of stomach cancer.
A study found that H. pylori infection increases the risk of noncardia gastric cancer but decreases the risk of cardia gastric cancer. This may explain changing cancer rates in Western countries over the past century.
A new study finds that hospice enrollment rates vary more by health center than individual patient characteristics. Additionally, a meta-analysis suggests that high processed meat consumption is associated with an increased risk of stomach cancer, while another study identifies a potential target for leukemia treatment and notes the pe...
Researchers at Rhode Island Hospital are awarded a $665,000 NIH grant to investigate the link between H. pylori bacteria and stomach cancer. The goal is to prevent gastric cancer by identifying a cause that can be prevented.
Despite declining overall mortality, US cancer incidence rose slightly among women in 2002 compared to the previous decade. The study also found that some cancers, like leukemia and non-Hodgkin lymphoma, experienced increased incidence.
The study reveals that hyperactive Stat3 shuts down a vital controller of stomach cell growth, leading to cancer formation. Lowering Stat3 hyperactivity suppresses stomach cancer formation without affecting other roles in the body.
Researchers studied the combination of S-1, a new drug, and cisplatin in patients with advanced gastric cancer. Overall, 65% of patients responded to the chemotherapy, showing tumors shrunk in response to the drug.
Researchers found a modest increase in colorectal cancer incidence in families without MMR deficiency, but no increased risk for other malignancies. These findings allow clinicians to provide more accurate and lower-risk information to affected families.
A recent study published in Developmental Cell reveals a crucial molecular pathway involved in the development of precancerous stomach lesions, which could lead to improved diagnosis and prevention strategies. The research, conducted by Dana-Farber Cancer Institute scientists, identified a key player in this signaling pathway as a tran...
Researchers found that chronic gastritis can progress to gastric cancer in mice with abnormally low levels of gastrin. The study identified key genes and molecular changes involved in the development of human gastric cancer.
Researchers at Emory University Health Sciences Center have identified a new tumor suppressor gene, ATBF1, which inhibits cell proliferation. This finding suggests that ATBF1 may play a role in the development of prostate cancer and potentially other types of cancers.
The report reveals that nearly 2.9 million new cases of cancer were diagnosed in Europe in 2004, with lung cancer being the most common form. Breast cancer is also on the rise, while stomach cancer rates are falling. The study emphasizes the need for a joint European effort to combat these diseases.
A Swedish cohort study found that larger babies had a higher risk of certain adult cancers, including lymphatic and digestive cancers. Women who were large at birth were also more likely to develop breast cancer before age 50.
Researchers found that excessive build-up of succinic acid in mitochondria triggers a sequence of events leading to tumour growth. The study increases understanding of molecular basis of several types of cancer, crucial for developing new prevention, diagnosis and treatment methods.
Researchers analyzed data from Iceland's National Cancer Registry and deCODE genetics database to investigate cancer risk in families. The study found that for 16 out of 27 cancers studied, relatives of patients were at a significantly higher risk of developing the same type of cancer. Lifestyle factors like smoking and diet also contr...
Researchers found that chronic Helicobacter pylori infection leads to the death of normal stomach cells, prompting bone marrow-derived stem cells (BMDCs) to arrive and transform into cancer cells. This discovery may aid in early diagnosis and treatment targeting BMDCs.
Researchers are exploring the potential of tomato oil to reverse or delay progression of high-grade prostatic intraepithelial neoplasia (HGPIN), a precursor to prostate cancer. The study, led by Dr. Peter Gann, aims to clarify lycopene's mechanisms in the prostate and determine its chemopreventive potential.
A new study found a link between men's height and their risk level for advanced prostate cancer, with tall men experiencing a 20% increased risk. Additionally, researchers discovered that fruit and vegetable consumption, particularly vitamin C and lycopene, may reduce the risk of stomach cancer by up to 45%.
Researchers found that a specific glycoprotein, O-glycans capped with alpha 1,4-linked N-acetylglucosamine, blocks H. pylori's ability to synthesize cholesterol, leading to cell death and potential treatment for stomach ulcers and cancer. The study suggests a natural defense mechanism against H. pylori infection.
Researchers found a significant association between H. pylori infection and reduced risk of esophageal adenocarcinoma, but a two-fold increased risk of squamous-cell carcinoma. Gastric atrophy was not linked to disease risk, suggesting an alternative pathway from H. pylori to cancer.
A recent report shows a significant decline in stomach cancer rates across Europe, with falls seen in younger and middle-aged populations. The downward trend is attributed to improved diet, better food preservation, reduced Helicobacter pylori infection, and lower smoking rates.
Researchers found that calcium supplements reduced the risk of colorectal cancer recurrence only among individuals with baseline vitamin D levels above the median. Serum vitamin D levels were also associated with reduced adenoma recurrence among individuals taking calcium supplements.
Researchers found that Hedgehog's signal is required for cancer growth in the digestive tract. A plant-derived chemical called cyclopamine blocked this signal, killing tumors in mice without harm.
The report analyzed data from 22 countries and 42 types of cancer, showing average five-year survival rates ranging from 94% for lip cancer to less than 4% for pancreatic cancer. Regional variations were found, with some Eastern European countries having lower survival rates and western Europe performing better.
A new chemotherapy regimen combining docetaxel with cisplatin and 5-Fluorouracil has been shown to significantly improve survival rates in late-stage stomach cancer patients. The study found a nearly 80% higher chance of tumor shrinkage and a reduced risk of cancer growth.
A study has identified specific combinations of H. pylori bacterial strain and host genetic variations that increase the risk of stomach cancer in infected individuals. These findings suggest that personalized genotyping can help identify high-risk individuals, who may benefit from targeted H. pylori eradication treatment.
Researchers have discovered a key molecule involved in regulating the immune system that may contribute to stomach cancer. Mutations to this molecule, gp130, induced cellular changes reminiscent of early gastric cancer in mice, highlighting a potential new target for treatment.
In developed countries, cancer mortality is more than twice as high as in developing countries due to factors like tobacco consumption and Western nutrition. In contrast, up to 25% of malignancies in developing countries are caused by infectious agents, whereas chronic infections account for only 8% in developed nations.
Scientists from Johns Hopkins Medicine have discovered that sulforaphane, a compound found in broccoli, kills the bacterium Helicobacter pylori, which causes stomach cancers and ulcers. The findings suggest that dietary intake of vegetables containing sulforaphane could relieve infection and have significant public health implications.
A recent study published by researchers at the University of Southern California found that polyphenols in tea may be associated with a lower risk of gastric and esophageal cancer. The study followed 18,244 men aged 45-64 in Shanghai, China, and found that those who consumed more tea had a 50% lower risk of developing these cancers.
A new study by researchers at Thomas Jefferson University found that the protein GCC is present in intestinal metaplasia, a sometimes precancerous condition in the esophagus and stomach. GCC's presence was detected in five of five cases of esophageal cancer and eight of nine cases of stomach cancer.
A recent study found racial and ethnic disparities in the receipt of cancer treatments, with white patients often receiving more aggressive therapy than minority groups. The study analyzed data from 87 studies and found consistent differences in therapy, including less frequent surgery for lung and colorectal cancers among minorities.
A study published in the American Journal of Clinical Nutrition found that diets high in red meat, such as high meat or high milk diets, are associated with a higher risk of stomach and esophageal cancers. Diets rich in fruits, vegetables, and whole grains may help reduce this risk.
A large study found that animal-based nutrients are strongly associated with increased risk of stomach and esophageal cancers. Conversely, a diet rich in plant-based nutrients, such as dietary fiber and vitamin C, may help lower cancer risk.
A recent meta-analysis shows a three to sixfold increased risk of non-cardia stomach cancer in H.pylori positive individuals. This suggests that at least half of all non-cardia cancer cases can be attributable to the infection, with potentially much more.
A University of North Carolina at Chapel Hill study found that regular garlic consumption reduces stomach cancer risk by half and colorectal cancer risk by two-thirds. The researchers pooled data from 22 studies worldwide to confirm the protective effect, but note that supplements may not be as effective.
Researchers at Thomas Jefferson University have discovered a new connection between the FHIT gene and hereditary colorectal cancer. The study suggests that the FHIT gene plays a crucial role in preventing carcinogen-caused tumors, and its loss may contribute to the development of HNPCC-like disease.
Researchers at Brown University have developed a drug and radiation regimen that demonstrates substantial activity in reducing locally advanced and inoperable tumors in the pancreas and stomach.