Articles tagged with Tissue Damage
Researchers found that head trauma impairs brain cells' ability to detect and repair DNA damage, leading to weeks of prolonged cell death. The study suggests that the body's surveillance system breaks down after an injury, making it difficult for cells to recover.
Researchers at UCSF have identified a transcription factor, human Cdc5 (hCdc5), that regulates the cell cycle and may help stimulate heart muscle cell repair after damage. The discovery could lead to new treatments for children with heart abnormalities and potentially benefit 900,000 American adults affected by heart attacks each year.
Researchers developed a sensitive and accurate probe to measure cartilage damage, using ultrasound and load cell units. The probe can be used arthroscopically, allowing for precise assessment of cartilage thickness and mechanical strength before surgery.
Prof. Michal Schwartz's research reveals a unique relationship between the central nervous system and immune system, showing that immune cells can aid in healing damaged nerves. This discovery may lead to new treatments for nerve damage and autoimmune diseases like multiple sclerosis.
Weizmann Institute scientists develop a novel approach to heal damaged spinal cords in rats, regaining partial motor activity and movement. The treatment promotes the animal's own self-repair mechanism, paving the way for further research on human applications.
A protein called osteogenic protein-1 (OP-1) may speed the recovery of stroke patients by rewiring damaged brain cells. The experiment used rats and showed that OP-1 helped them recover lost movement in their limbs quickly, outperforming those in a control group.
Researchers create ultra-sensitive assay to detect DNA damage caused by ionizing radiation and cancer-causing chemicals, showing potential for early detection and treatment of genetic injuries. The new technique is 10,000 to 100,000 times more sensitive than existing methods.
Researchers used a novel test to measure damaging activity of free radicals in body tissues, finding high levels in atherosclerotic plaque tissue. The technique provides a real handle on oxidant processes in atherogenesis and could lead to clinical studies testing efficacy of drugs limiting free-radical damage.
A new study suggests that inhibiting poly(ADP-ribose) polymerase (PARP) enzyme may protect nerve cells from energy loss and prevent irreversible damage after a stroke. The research, published in Nature Medicine, found that genetically modified mice without the PARP gene experienced reduced brain damage compared to unaltered mice.
Researchers found that C-peptide protein repaired damaged blood vessels and nerves in diabetic rats, suggesting a new approach to preventing cardiovascular disease in both types of diabetes. The protein's unique mechanism of action may be key to understanding its effects on cell function.