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A growth factor reverses nerve damage in diabetic animals

A recent study reveals that long-term nerve damage in diabetic rats can be reversed by treatment with an insulin-like protein. The protein may prevent or alleviate certain nerve complications associated with diabetes, such as irregular blood pressure control and digestive issues. Researchers are hopeful about the potential therapeutic ...

SourceWashU Medicine·JournalAmerican Journal Of Pathology·DateOct 31, 1999

UCSF Scientists Report On A Transcription Factor That Could Stimulate Heart Cells To Repair Damage Caused By Heart Attacks Or Birth Defects

Researchers at UCSF have identified a transcription factor, human Cdc5 (hCdc5), that regulates the cell cycle and may help stimulate heart muscle cell repair after damage. The discovery could lead to new treatments for children with heart abnormalities and potentially benefit 900,000 American adults affected by heart attacks each year.

Rewiring The Brain

A protein called osteogenic protein-1 (OP-1) may speed the recovery of stroke patients by rewiring damaged brain cells. The experiment used rats and showed that OP-1 helped them recover lost movement in their limbs quickly, outperforming those in a control group.

SourceNew Scientist·JournalThe New Scientist·DateJun 17, 1998

New Discovery May Offer Protection Against Stroke

A new study suggests that inhibiting poly(ADP-ribose) polymerase (PARP) enzyme may protect nerve cells from energy loss and prevent irreversible damage after a stroke. The research, published in Nature Medicine, found that genetically modified mice without the PARP gene experienced reduced brain damage compared to unaltered mice.

SourceJohns Hopkins Medicine·JournalNature Medicine·DateSep 29, 1997