Articles tagged with Infectious Disease Transmission
A study by University College London found that human impacts increase the risk of emerging infectious disease outbreaks, particularly in areas with fragmented ecosystems and climate change. The researchers identified a clear 'anthropogenic fingerprint' on the global geography of emerging infectious diseases, with factors driving outbr...
Researchers uncover molecular mechanism by which Plasmodium falciparum increases gametocyte production in response to stress, enabling rapid transmission to mosquitoes. The study identifies key regulators, including GDV1 and AP2-HS, that trigger a regulatory feedback loop to control gametocyte production.
A multidisciplinary group of researchers examines potential interactions between urban green spaces, vector-borne diseases, and climate change to inform 21st century public health decisions. The study highlights the need for balancing benefits of urban green spaces with risks of vector-borne diseases under climate change.
Researchers discovered PECAM-dependent mechanism for immune cell traffic in the retina, identifying neutrophils as proresolving mediators. Targeting PECAM controlled white blood cell traffic, leading to improved clinical outcomes in uveitis model.
Denmark's unique approach to prenatal care, including universal syphilis screening, has led to zero congenital syphilis cases since 2016. The study found nearly 100% screening coverage and a stable trend in syphilis infections, but no increase in congenital syphilis cases, indicating a well-functioning healthcare system.
The Workshop on Public Health Policy, Risk Perception, and Infectious Disease successfully bridged the gap between epidemiological modeling and policy implementation for infectious diseases. Participants discussed practical challenges and mutual benefits of using models to support public health decision-making.
A new AI method called neural posterior estimation (NPE) uses genetic sequences to analyze the evolution of infectious diseases. This allows for real-time management of epidemics and epizootics, with the ability to add new data at any time.
A new study from the University of East Anglia found that people who swim in rivers and lakes are more than twice as likely to develop skin problems. Higher levels of bacteria linked to faecal pollution are also associated with an increased risk of stomach bugs. The study, which analyzed data from 2,368 volunteers, found that swimmers ...
Tuberculosis bacteria can evolve to withstand airborne transmission and generate antibiotic resistance, according to a new study. Researchers identified a DNA repair gene called Mfd that helps certain drug-resistant strains survive transmission.
A study reveals that glacier retreat and changing vegetation may increase the overlap in resource use among bee species, potentially leading to pathogen transmission. This could have significant consequences for pollinator health and ecosystem services.
A new study explains why drought can both reduce and increase waterborne diseases. The authors identified three mechanisms that determine whether a parasite will thrive or die out during drought: host-parasite concentration, desiccation traps, and changes in water quality.
Researchers have compiled ten fundamental mechanisms governing the development of pandemics, highlighting the importance of understanding biological, mathematical, and social factors. These mechanisms can help improve preparedness and response to future pandemics by identifying key drivers of outbreak dynamics.
Researchers developed a model to optimize countermeasures while considering containment costs, identifying a clear threshold for optimal control. The study found that measures become necessary only when the disease reaches a certain severity, and that vaccination campaigns can help reduce transmission rates.
Researchers in India have identified β-esterase as the primary enzyme involved in α-cypermethrin detoxification, showing increased reactivity in response to the insecticide. This finding suggests that mosquitoes can dramatically increase production of a particularly effective enzyme when exposed to a threat.
Researchers developed a mathematical model to reconstruct COVID-19 spread in Dutch schools, showing that targeted closures can reduce hospital admissions. The study highlights the value of mathematical models for informing public health decisions during outbreaks.
A new study found that invasive plant species in low-income neighborhoods boosted mosquito growth and survival, leading to larger mosquitoes capable of transmitting disease. By planting native tree species, cities can reduce mosquito infestations and protect against mosquito-borne diseases.
The University of Minnesota Medical School research team has received a $10 million NIH grant to study how animals fight infection. The team will utilize a 'cellular zoo' of living cells from over 100 animal species to understand how different species recognize and respond to viral infections.
Researchers uncover how a family of tick-borne viruses, known as orthonairoviruses, evade the immune system by manipulating cellular communication pathways. This study highlights a significant pandemic risk posed by these viruses and emphasizes the need for continued surveillance and preparedness.
A case study in eastern Ontario highlights the importance of considering tick-borne diseases as part of the infectious workup. Anaplasmosis, a growing public health concern in Canada, can cause symptoms such as fever, weakness, headache, and gastrointestinal distress.
A large dengue outbreak in Italy was analyzed to identify transmission patterns. The data show that more than half of linked transmission events involved people within 100m apart. Temperature played a role in reducing transmission, with a drop in autumn temperatures contributing to the decline.
A new analysis of state health department data reveals that more than 6,400 Illinois residents were diagnosed with tickborne diseases from 2004-2022. Lyme disease is the most common tickborne malady in humans in the state, accounting for 4,297 infections.
JMIR Publications invites submissions on the 2026 Ebola disease public health emergency of international concern, focusing on response strategies, risk communication, and surveillance. The World Health Organization has declared a public health emergency due to population mobility and ongoing uncertainty in the Democratic Republic of th...
Researchers at the German Center for Infection Research have developed a promising single-dose malaria treatment called SPAP, which targets the malaria parasite through multiple mechanisms. The four-drug combination therapy has shown significant promise in improving malaria treatment and could be a major advancement in sub-Saharan Africa.
A study analyzing all known Ebola disease cases outside Africa since 1976 found a low overall risk of exportation. Local, community-based case management and infection prevention at the outbreak source are considered key strategies to mitigate transmission risk.
Aberystwyth University experts Dr Kate Parsons and Dr Simon Payne will lead sessions on boosting vaccine uptake at the upcoming international meeting in Colombia. The workshop aims to bridge the gap between laboratory research and real-world impact by applying behavioural science principles to improve vaccine acceptance and delivery.
Research at Ohio State University found that just 10 viral particles can cause H5N1 avian flu infection in cows. The study also suggests that the virus has an affinity for cow mammary glands rather than airways.
Scientists at La Jolla Institute for Immunology have discovered that 'cross-reactive' T cells can recognize multiple species of paramyxovirus, including measles and Nipah viruses. This broad protection is essential in combating emerging diseases with unknown viral strains.
Chlamydia notifications decreased in seven European countries, with significant declines among young people. The decline was mainly seen in Sweden, Denmark, England, Finland, Ireland, Norway and the Netherlands, with case numbers dropping by up to 32% in some countries.
Researchers found that yellow fever mosquitoes can learn to associate the smell of DEET with food, leading to a significant reduction in their repellent effect. The study suggests that the timing and concentration of DEET application may be more crucial than previously thought.
Europe's bacterial STI cases reached record highs in 2024, driven by gonorrhoea and syphilis, with men who have sex with men disproportionately affected. The near doubling of congenital syphilis cases highlights the need for improved antenatal screening protocols to prevent transmission to newborns.
Researchers at La Jolla Institute for Immunology have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine. This approach may protect against life-threatening infections from Lassa virus, Junin virus, and many other arenaviruses.
Researchers used wastewater surveillance to detect drug-resistant Candida auris strains up to five months before patients showed symptoms, opening a new frontier for hospitals. The study found higher detection rates and concentrations of the pathogen in hospital wastewater compared to community-scale treatment plants.
A study found that airborne viruses can spread between separated indoor spaces through shared bathroom ventilation systems. The study, conducted in a high-rise building in Spain, confirmed COVID-19 transmission through vertical ventilation shafts, highlighting the risk of disease transmission in older buildings.
The CCRE survey provides the most comprehensive genomic picture to date of carbapenem- and/or colistin-resistant Enterobacterales across European hospitals. The results reveal heterogeneous yet increasingly concerning epidemiological patterns, suggesting a high risk that carbapenem-resistant E. coli could become endemic in Europe.
Researchers identified how Mycobacterium abscessus evades treatment and proposed a strategy to overcome resistance, offering a pathway towards more effective treatments. A combination therapy targeting both smooth and rough variants proved more effective than single-phage treatment.
A new study projects that climate change will drive rodent-borne arenaviruses into new regions of South America, posing a future threat to millions of people. The researchers built an interactive platform to understand the complex relationships between climate, land use, and human exposure.
A new analysis found that prescriptions for curable hepatitis C drugs have declined sharply in recent years, leaving millions without treatment. The researchers urge swift actions to deliver the drugs to those who need them, including increased screening and system-level changes.
Keratinocytes play a more active role in rabies infection than previously thought, supporting viral replication and transmitting the virus to neurons. This discovery provides new insights into the risk of infection from superficial scratches or minor bites.
Researchers have found that COVID vaccines can train immune cells to remember the SARS-CoV-2 virus and protect against severe infection for years afterward. However, the continued spread of disease has scientists taking a closer look at how the immune system builds up immune memory over time.
Researchers developed an innovative multi-host epidemiological model to study African swine fever (ASF) transmission between domestic pigs and wild boars. The model found that inter-farm transmission was the primary driver sustaining outbreaks, while nearby infected wild boar populations played a significant role in ASF spread.
Researchers discovered that inhibiting tick salivation prevents infection by targeting the tick's nervous system and salivary glands. The study found two distinct signalling pathways controlling saliva secretion, with acetylcholine playing a key role in stimulating salivation.
Researchers have discovered how a disease-causing bacterium uses a single protein to interfere with the body's defenses in multiple ways, offering a clearer picture of how infections take hold at the cellular level. This discovery highlights the importance of targeting specific interactions between bacterial proteins and human cells in...
A new study suggests that ultra-sensitive food safety tests may drive food waste and unavailability without significant public health benefits. The researchers propose using more flexible risk-based approaches to align food safety policies with sustainability goals.
A study by Frontiers in Science argues that ultra-sensitive food safety tests may drive food waste and unavailability, but not always translate to health risk. The researchers propose a more balanced approach that considers trade-offs between food safety, sustainability, and nutritional health.
Researchers at Penn State found that Ebola outbreaks are influenced by environmental and human factors, including weather patterns, vegetation health, and human movement. A strong positive correlation was found between the total length of roads and rivers in outbreak locations and the number of Ebola cases reported early in each outbreak.
A new index maps state-level flu risk, highlighting regional disparities and socioeconomic factors contributing to vulnerability. Policymakers can use this tool to develop targeted strategies, strengthen epidemic preparedness, and address disparities in flu risk across the US.
Researchers found that tick infection prevalence in Ohio has increased to 47.6%, comparable to endemic US regions like Connecticut. The study suggests that Ohio's forested areas have the same risk of Lyme disease as Connecticut.
A sweeping new study has identified tuberculosis as the predominant cause of deadly sepsis among people with HIV in Africa. Immediate treatment for TB significantly increased survival rates, especially when treatment was started before diagnosis.
The new platform developed by UVA Health scientists can produce vaccines much faster, cheaper, and more easily than traditional approaches. The platform's proof-of-concept demonstrates its ability to produce highly immunogenic vaccines that can be manufactured at extremely low cost.
Researchers at NUS Medicine discovered that genetic vectors can efficiently spread antibiotic resistance within the gut, enabling even highly virulent bacteria to acquire drug resistance. This finding sheds light on the emergence of 'superbugs' in healthcare settings.
Researchers at the University of Arizona have developed a copper-based compound that can kill MRSA bacteria by disguising itself as iron. The compound, BMDC, works by delivering a toxic dose of copper to bacterial colonies, making it an effective treatment against drug-resistant infections.
Researchers at UC Santa Barbara found that human activity in the Amazon basin is driving an uptick in yellow fever cases. The proximity of urban areas to forests increases the risk of disease transmission, as does the growing border between forested and urban areas.
A new study found that airborne transmission of the flu is a major factor in its spread, but ventilation and air movement can reduce transmission. The study used a controlled environment to investigate how the flu spreads through the air between infected and uninfected people.
Researchers discovered that GBS interacts with C. albicans, increasing the risk of severe and fatal infections in newborns and making standard treatments less effective. The co-infection can also reduce the effectiveness of existing GBS treatments.
Researchers used computer modeling to reconstruct the spatial transmission of the 2009 H1N1 flu and COVID-19 pandemics in the US, highlighting challenges of early outbreak containment and identifying key transmission hubs. The study suggests expanding wastewater surveillance coverage could slow initial spread of future pandemics.
Researchers describe first reported mpox transmission of clade Ib in a healthcare setting outside Africa, with Ireland's nosocomial outbreak linked to local cases. In the Democratic Republic of Congo, community transmission shifted from sexual to non-sexual routes, driven by factors like overcrowding and child malnutrition.
The emergence of A(H3N2) subclade K viruses in Australia and New Zealand extended their influenza seasons, with Australia experiencing a record-breaking season. The viruses were likely imported from the US and accounted for half of Australian viruses and over two-thirds of New Zealand viruses.
A new study found that adults hospitalized with RSV often struggle with breathlessness, reduced ability to perform everyday activities, and lower quality of life six to 12 months after their hospitalization. The study also showed that younger adults can experience serious RSV infections requiring hospitalization, similar to older adults.
The new guideline recommends full-time infection prevention staff, comprehensive training, and support for all staff, as well as partnerships with hospitals and public health agencies. This guidance aims to reduce the risk of infections in nursing homes, saving lives and money.
The APIC and SHEA have established the Healthcare Infection Prevention Advisory Group (HIPAG) to fill gaps in coordinated infection prevention efforts. The group aims to provide timely, evidence-informed advisory expertise to support organizational needs and promote alignment among healthcare stakeholders.