Articles tagged with Infectious Disease Transmission
A new UNLV-led study uses AI to detect emerging virus variants in wastewater samples, outperforming existing methods. The algorithm can identify unique signatures for different virus variants with as few as two to five samples, significantly earlier than current methods.
The BA.2.86 Omicron strain was found to have emerged with a high number of genetic mutations in its spike protein, but failed to become a dominant strain. Its sporadic global detection has raised questions about the possibility of laboratory involvement in its emergence.
A Danish study finds that HPV vaccination has reduced prevalence of high-risk HPV types among vaccinated women, suggesting population immunity. However, non-vaccine types remain common and new infections occur more frequently in vaccinated women than unvaccinated women.
Diphtheria is still being reported in Europe, with cases higher than before 2020, affecting vulnerable populations like homeless individuals, migrants, and those who use or inject drugs. ECDC recommends tailored public health response measures to protect these groups.
A recent study in the Netherlands found 15% of men who have sex with men and transgender individuals recently used doxycycline as post- or pre-exposure prophylaxis (PrEP), highlighting an increase in informal use. The high intention to use PrEP among the population raises concerns about potential antimicrobial resistance (AMR) and chan...
Scientists at the Stowers Institute and University of Georgia discover how Cryptococcus neoformans thrives, identifying over 300 potential targets for novel antifungal drugs. The study provides an atlas for developing new therapies to combat this lethal fungus.
A new study published in Biological Conservation shows that protocols such as quarantining, masking, and more can help prevent outbreaks like the one at Ngogo. Researchers observed a clear decrease in viral shedding and fewer instances of persistent coughs after stricter protocols were implemented.
Researchers at UMass Amherst have identified a naturally occurring compound secreted by donkeys that effectively repels adult Ixodes scapularis ticks, the primary tick species responsible for spreading Lyme disease. The compound, (E)-2-octenal, shows promise as a natural alternative to DEET-based repellents.
A new study finds that bats are a reservoir for morbilliviruses, including the human measles virus, and can transmit them to other mammalian species, such as monkeys. The research suggests that these viruses have crossed species boundaries multiple times, posing a significant threat to human health and livestock.
Researchers found that an inexpensive HIV drug can improve vision in patients with diabetic macular edema (DME) more effectively and at a lower cost than existing treatments. The drug, lamivudine, is taken orally and may represent a game-changing option for millions of patients worldwide.
Researchers mapped the evolution of Borrelia recurrentis, a type of bacteria causing relapsing fever, by analyzing ancient DNA. The study found that the species likely diverged from its tick-borne cousin around 6,000 years ago and gained new genes over time, allowing it to spread through human lice.
A Johns Hopkins Medicine study finds that SARS-CoV-2 corrupts white blood cells, specifically neutrophils, to impair the production of immune cells critical for fighting COVID-19. This reprogramming may lead to severe COVID cases by weakening the immune response against the virus.
A new study by University of California San Diego researchers found that the SARS-CoV-2 virus emerged in humans via wildlife trade, not a lab leak. The viruses most closely related to SARS-CoV-1 and SARS-CoV-2 were found in palm civets and raccoon dogs in southern China.
A new study uses foot traffic data to enhance neighborhood-level COVID-19 forecasts in New York City. The research reveals how routine activities like dining out and shopping became major transmission pathways, enabling the development of a behavior-driven model that outperforms traditional forecasting methods.
Researchers discovered how urban rat migration spreads leptospirosis, a deadly disease, and developed a novel technique for testing rat kidneys. The study used advanced molecular techniques to analyze DNA from 328 rat kidney samples collected from 17 sites in Boston, finding that 59 rats were positive for Leptospira bacteria.
A new study found that many home washing machines are insufficient for decontaminating healthcare worker uniforms, allowing antibiotic-resistant bacteria to survive. The researchers propose revising laundering guidelines or using on-site industrial machines to improve patient safety.
Mathematical modeling research from University of Utah Health suggests that treating moderate cases with antibiotics could limit the spread of cholera and reduce the likelihood of antibiotic resistance. In areas where cholera spreads slowly, aggressive antibiotic use may even stop outbreaks entirely.
A new study reveals emerging cases of babesiosis in the Mid-Atlantic region, documenting human cases and detecting Babesia microti in local tick populations. The research highlights the growing public health threat posed by this tick-borne disease, emphasizing the need for increased surveillance, public awareness, and preventive measures.
The European Centre for Disease Prevention and Control (ECDC) emphasizes the need for high immunization coverage to protect European populations from diseases like measles and polio. Vaccination remains a crucial tool in public health, with recent data showing a tenfold surge in reported measles cases in the EU/EEA.
A hospital-based outbreak detection system has been shown to prevent infections, save lives and cut costs. The Enhanced Detection System for Healthcare-Associated Transmission (EDS-HAT) uses genomic sequencing to analyze infectious disease samples from patients, identifying near-identical strains that flag potential outbreaks.
A comprehensive analysis published in The Lancet Regional Health—Americas highlights the growing concern of H5N1 avian influenza. Key findings include the virus's ability to infect both animals and humans, with nearly 1000 dairy cow herds affected and over 70 human cases reported.
The CDC has awarded a $3 million grant to the Texas A&M School of Public Health to investigate avian flu among dairy farm workers in Texas. The team, led by Dr. David Douphrate, aims to identify the scope of exposure and workplace factors involved in transmission.
A landmark study found that a single oral dose of baloxavir marboxil significantly reduces influenza transmission within households. Conducted across 15 countries, the CENTERSTONE trial provides robust evidence for an antiviral treatment's potential to curb the spread of influenza.
The EU/EEA is struggling to reach 2030 SDG targets for HIV, TB, viral hepatitis B and C, and STIs, with many countries not on track. Despite progress in some areas, significant data gaps hinder a complete assessment.
A mathematical modeling study suggests that sustained HIV remission or eradication could consistently reduce new HIV infections among men who have sex with men (MSM) in the Netherlands. However, transient remission with a risk of rebound may increase new infections if not closely monitored.
A new study models cholera transmission after interventions in the Democratic Republic of the Congo, highlighting the importance of environmental reservoirs in maintaining endemic diseases. The research suggests that vaccination may have a smaller impact on preventing transmission compared to water, sanitation, and hygiene improvements.
Researchers found Oropouche virus is massively under-diagnosed in Latin America, with over 1 in 10 people experiencing a prior infection. Climatic conditions, including rain and temperature, significantly influence the virus's spread, posing risks to unborn babies.
A University of Ottawa-led team examines the punishing costs of TB care, finding that patients face 'catastrophic' expenses despite free treatment being available in many countries. The review identifies areas for intervention to reduce patient costs and improve sustainable TB mitigation strategies.
A new study led by researchers at UC Santa Barbara found that the black rat is likely responsible for transmitting deadly hantaviruses in rural Madagascar. The virus was exclusively found in rats, with larger, adult rats more likely to be infected.
A new study found that Clostridium difficile infection spreads more than three times more than previously thought within intensive care units, with bacteria moving between patients and hospital surfaces. The researchers tracked bacterial movement using whole genome DNA sequencing and discovered cases of potential transmission that woul...
Researchers developed an antiviral chewing gum containing a natural protein that neutralizes viral loads of influenza A strains and two herpes simplex viruses. The gum, made from lablab beans, was found to be safe and effective in reducing viral loads by over 95%.
A project aims to understand how temperature, light pollution, and bird abundance affect West Nile virus transmission in mosquitoes. The goal is to advise health departments on the best time to kill bugs and limit transmission.
Researchers have identified a new class of antibiotic that targets Neisseria gonorrhoeae, the bacterium causing gonorrhoea. The novel substance uses a unique mechanism to activate a self-destruction program in gonococci, killing the bacteria without harming other microorganisms or human cells.
Researchers at the University of Surrey warn that mpox's sustained human-to-human transmission poses a significant risk to global health. The virus can cause a painful rash, fever, and swollen glands, and has the potential to spread among children, who are at greater risk of serious illness.
A new study found that reported tuberculosis diagnoses among incarcerated people in Europe and the Americas plummeted by up to 100% during the pandemic, despite consistent incarceration rates. This reduction was distinct from general population trends, highlighting the need for improved healthcare systems within prisons.
Researchers have identified nitisinone as a medication that can suppress mosquito populations by making human blood toxic to them. The drug, used to treat rare genetic diseases, has been shown to be more effective than ivermectin in killing mosquitoes and has the potential to control malaria spread.
A new study finds that Canada is the slowest country to report genetic information about bird flu, with an average time of 618 days. However, the same researchers note that Canada was able to improve its response to COVID-19, highlighting the need for similar urgency in addressing this public health threat.
A new rapid diagnostic test can accurately identify pregnant women with high levels of the hepatitis B virus, allowing for early detection and intervention. This breakthrough test could have a significant impact on hepatitis B management in low- and middle-income countries, reducing the spread of the infection.
Childhood tuberculosis cases in the EU/EEA have increased by 26% over the past three years, with young children under 15 accounting for 4.3% of all TB cases. The rise in pediatric TB has raised concerns about incomplete treatment, drug-resistant TB, and further transmission.
A collaborative research effort has provided new insights into the likelihood of mpox spreading by airborne respiratory particles, comparing it to SARS-CoV-2 and smallpox. The study suggests that future viral evolution could alter this dynamic, underscoring the need for continued surveillance.
Researchers at WVU have discovered a way to fine-tune zinc activity to improve messaging in the brain, with potential applications for treating conditions such as autism, schizophrenia and Alzheimer's disease. The study identified new compounds that can selectively change synaptic connections by modulating zinc levels.
The European Centre for Disease Prevention and Control (ECDC) reports a rise in tuberculosis cases among children and adolescents in the EU/EEA, with a slight increase in the notification rate from 2.0 to 2.5 per 100,000 population. The highest proportion of paediatric TB was observed in children aged 1 to 4 years old.
A new article from the NYC Preparedness & Recovery Institute assesses the city's response to the pandemic, highlighting key findings on mutual aid networks and their role in emergency response. The study identifies strategies to strengthen emergency preparedness moving forward.
The Asia-Pacific region's H. pylori treatment practices show a growing consensus on primary and secondary prevention, but differences in antimicrobial resistance and medical resources persist. Establishing uniform standards for gastric cancer prevention will be crucial to addressing these disparities.
Oropouche virus has been reported in travellers from Canada and the US who visited Bolivia, Brazil, Peru, and Cuba, with symptoms including fever, chills, headache, and muscle aches. The risk of miscarriage and microcephaly is high for pregnant individuals, prompting cautionary measures.
Consuming raw milk and its products increases the risk of foodborne illness, including from Salmonella, E. coli, and Campylobacter. The Centers for Disease Control and Prevention have detected H5N1 bird flu in raw milk, posing a risk to human health.
A recent study by Oregon Health & Science University and Weill Cornell Medicine has found that CMV lacking a certain viral protein complex can still be transmitted and cause significant harm to the developing fetus. The research suggests that additional vaccine targets need to be identified and explored to provide superior protection.
The European Centre for Disease Prevention and Control reports a significant increase in measles cases across EU/EEA countries, with eight out of ten unvaccinated individuals contracting the disease. Vaccination levels fall short of the 95% target, leaving vulnerable populations susceptible to measles.
Researchers at Weill Cornell Medicine and MIT discovered a family of genes necessary for tuberculosis bacteria to survive airborne transmission. These genes help the bacteria adapt to changes in temperature, oxygen levels, and humidity, providing new targets for therapies that could treat infection and prevent spread.
Researchers developed a prototype sensor that detects H5N1 viruses in air samples, detecting the virus at levels below an infectious dose. The sensor produced results within 5 minutes and showed over 90% accuracy compared to traditional methods, offering promise for noninvasive air monitoring.
A landmark study reveals that bacterial vaginosis is a sexually transmitted infection, causing infertility and premature births. Treating both partners simultaneously achieves significantly higher cure rates than current practice.
Researchers at Aalto University and others have developed a model that shows smartwatches can accurately detect viral infections several days before symptoms appear. This early detection can lead to significant reductions in disease transmission and could potentially stop a pandemic before it starts.
Recent studies demonstrate that smartwatches can detect infections early through subtle physiological changes, prompting timely action to slow disease spread. By identifying infections sooner and reducing social contacts, wearable technology may help contain future outbreaks and prevent pandemics.
Research finds over 25% of Egyptian milk and dairy products contain E. coli, with one strain causing a Japanese school outbreak; experts hope for effective treatment and prevention methods.
A study suggests that pre-existing immunity against seasonal H1N1 flu can reduce the severity of bird flu in ferrets. In the study, ferrets with prior H1N1 immunity were protected against severe disease and death caused by H5N1 bird flu, whereas those without prior immunity had more severe illness and fatal outcomes.
NalaGenetics' nationwide genetic screening program will screen up to 16,000 leprosy patients annually for the HLA-B*13:01 biomarker. This initiative builds on a successful pilot test and marks a significant step forward in global efforts to eliminate leprosy.
Researchers will investigate the interaction of fluid dynamics and Far-UVC technology to optimize its deployment in real-world settings. The project aims to make communities healthier by analyzing airflow patterns and aerosol distributions.
A Cornell University study used a computer model to predict the transmission of bird flu to backyard poultry when migratory mallards stop to rest. The researchers found that mallard ducks are natural carriers of avian influenza and can spread the disease to backyard poultry if they stop to rest in an area with high risk for introduction.
Researchers discovered that Zika virus uses a tunneling strategy to spread in placental cells, hijacking mitochondria to augment its propagation and survival. The study found that the formation of tiny tunnels is driven exclusively by a Zika protein called NS1, which triggers tunnel formation in uninfected cells.
Researchers have identified a new variant, clade 1b, of the mpox virus that has become more infectious and is spreading rapidly across borders. The study found that this variant primarily spreads through heterosexual contact in densely populated areas, with an estimated fatality rate of 3.4%.