Articles tagged with Infectious Disease Transmission
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A new study reveals that blowflies in southern Japan are carrying the bird flu virus, which could lead to transmission through contaminated surfaces, food sources, and water. This finding highlights the need for effective countermeasures to prevent and control the disease in poultry farms.
Researchers at WashU Medicine developed a nasal COVID-19 vaccine that halted transmission in hamsters, showing promise for controlling respiratory infections. The vaccine targeted the virus's entry points in the nose and mouth, reducing viral replication and preventing spread.
Researchers engineered human skin bacteria to produce less lactic acid, attracting fewer mosquitoes to mice. The engineered microbes reduced mosquito attraction by up to 64.4% and also prevented bites.
Researchers find significant association between illicit fentanyl use and HCV transmission, highlighting need for point-of-care testing and treatment access. The study suggests that fentanyl's short half-life may lead to increased risk of HCV transmission through frequent dosing and sharing.
Researchers detected SARS-CoV-2 in six common backyard species, including deer mice, Virginia opossums, and raccoons, with unique viral mutations found in some animals. The study highlights the need for broad surveillance and suggests that areas with high human activity may serve as points of contact for cross-species transmission.
The COVID-19 pandemic highlighted the importance of proper ventilation in buildings to prevent airborne infection transmission. Experts recommend developing interdisciplinary knowledge, investing in mechanical ventilation systems, and implementing equivalent ventilation methods for existing buildings.
A new study found that the incidence of hepatitis C virus (HCV) reinfection among men with HIV is 10-fold higher than primary infection rates in New York City. The researchers identified receiving semen in the rectum as the only risk factor for reinfection, contradicting previous assumptions about transmission routes.
Researchers found that most Powassan-positive bites cause nonspecific presentations without symptoms, and estimated 3,000-5,000 people in the US are exposed to ticks carrying the virus each year. The study used a new testing approach to detect the virus in ticks and linked it to human disease outcomes.
A Cornell University study reveals efficient and sustained mammalian-to-mammalian transmission of highly pathogenic avian influenza H5N1 between cows and from cows to cats and a raccoon. The virus shows high tropism for the mammary gland and infectious viral loads in milk.
Researchers at Stowers Institute for Medical Research have identified the dengue virus genome's use of less efficient codons in its host's machinery to replicate and spread. This discovery has implications for developing novel antiviral treatments and vaccines, as well as understanding the relationship between viruses and their hosts.
A team of researchers from Penn State College of Medicine identified KDR, a tyrosine kinase, as a potential drug target for treating diseases caused by human T-cell leukemia virus type 1 (HTLV-1). By blocking KDR, the viral protein Tax is degraded, leading to cell death and disruption of cancer-causing signaling pathways.
Researchers in Brazil identified two new serovars of Leptospira bacteria causing the disease, with one linked to cat ownership and increasing age. The study found that improving sanitary conditions and understanding animal contributions to transmission are key to preventing leptospirosis.
A recent study by the University of Exeter warns that intensive livestock farming may raise the risk of emerging infectious diseases (EIDs). The researchers highlight the need to consider social and economic factors in traditional assessments.
The University of Montana has received a $3 million federal grant to investigate three North American bat species' adaptations to white-nose syndrome and climate change. Researchers will use computational models, bioinformatics, and ecological data to forecast bat movement across landscapes and understand population resilience.
Researchers found that bovine HPAI H5N1 viruses induced severe disease in mice and ferrets after intranasal inoculation, with high virus levels detected in respiratory and non-respiratory organs. However, the virus did not transmit efficiently via respiratory droplets among ferrets.
A novel diagnostic test combining LAMP molecular amplification with a 3D printer-based DNA extraction system shows comparable sensitivity to PCR, offering a simple and rapid solution for detecting T. cruzi infection in newborns. Early detection is crucial for effective treatment, which was successfully applied in the study.
A study published in Clinical Infectious Diseases found that regular booster doses of bivalent vaccines can maintain a person's ability to neutralize multiple SARS-CoV-2 strains, including XBB.1.5. This is especially important for immunocompromised groups, such as solid organ transplant recipients.
Researchers at Ohio State University discovered the hepatitis E virus is associated with sperm in pigs, suggesting a possible link to male infertility and sexual transmission. The virus was found to circulate in blood and shed in feces, with viral particles present on the head of sperm cells that can infect human liver cells.
Studies found that wood reduces viral infectivity on its surface, with pine and spruce showing the fastest onset of antiviral activity. The researchers concluded that wood's chemical composition is responsible for its antiviral functionality.
Researchers have identified the spleen as a critical organ in cryptic malaria infections, where over 95% of Plasmodium vivax biomass is stored. Extracellular vesicles facilitate the parasite's adherence to spleen cells, enabling its survival and evasion of immune responses.
A study by Virginia Tech researchers found that shelter dogs paired with suitable companions exhibited reduced stress levels and were adopted more quickly. The findings suggest that matching dogs with compatible roommates could alleviate stress and improve their adoptability, leading to better outcomes for animal shelters.
A study in São Paulo state found that chikungunya virus circulated silently for years before causing major epidemics. The researchers monitored residents for four years and discovered a significant rise in seroprevalence from 0.35% to 2.3%. This finding underscores the need for strengthened disease surveillance.
A new study analyzed over 14,600 scientific publications funded by more than $4 billion in NIH grants, revealing key research topics such as clinical trials, vaccine distribution, and virology. The findings suggest that half of the funding went to five states: North Carolina, Washington, New York, California, and Massachusetts.
A review of research suggests that only around half of individuals feel comfortable disclosing their STI diagnosis to a partner before engaging in sexual activity. Comprehensive sex education is needed to prevent the spread of infections and support individuals with diagnosed STIs.
Researchers tracked mpox cases in a surveillance network of 13 emergency departments, finding three new cases among gay and bisexual men who have sex with men. The study highlights the need for vigilance and vaccination to prevent further transmission.
Experts at NYU Langone Health have warned of a growing public health threat from hard-to-treat fungal skin infections in the US. Two new reports document cases of highly contagious forms of ringworm and jock itch that can take months to clear up with treatment.
Researchers at the University of Toronto discovered a new RNA virus, Apocryptovirus odysseus, associated with severe inflammation in humans infected with Toxoplasma gondii. The virus is found in two hypervirulent strains of the parasite, exacerbating toxoplasmosis disease and triggering an immune response.
Researchers identified a novel virus in pet trade zebrafish that causes hemorrhaging in laboratory fish, revealing a risk of viral transmission. The study found that viruses circulating in healthy pet trade zebrafish can transmit to laboratory animals and cause severe disease.
A new analysis reveals that national-level data on rubella vaccination may overlook nuances at the local level, affecting vaccination efforts. Introducing a vaccine program can reduce CRS cases by thousands in the first five years.
A new study by Emory University researchers found a link between deforestation and rabies outbreaks in cattle in Costa Rica. The study suggests that decreased availability of bat-roosting sites within forested habitat may increase the preference of vampire bats to feed on cattle.
A recent laboratory study found that human body lice are more efficient at transmitting Yersinia pestis, the bacterium causing plague, than previously believed. The researchers discovered a new mechanism by which lice can spread the pathogen through bites, highlighting the potential role of body lice in past plague outbreaks.
The Planetary Child Health & Enterics Observatory (Plan-EO) is developing an online tool to identify diarrheal disease transmission hotspots and accelerate treatment deployment. The dashboard will provide up-to-date epidemiological estimates and predictions, enabling public health communities to make informed decisions and save lives.
A new NIH study using human cerebral organoids suggests a substantial species barrier preventing the transmission of chronic wasting disease from cervids to people. Researchers found no infection in healthy human cerebral organoids exposed to CWD prions for up to six months.
Scientists found that a specific strain of the H5N1 virus, which caused a 2022 mink outbreak, can transmit through the air to ferrets with limited effectiveness. The study suggests these viruses may be evolving to infect mammals and potentially pose increased risk to humans.
Boston University researchers have identified 10 drug compounds that can reduce PrP Sc levels in infected cells and prevent toxicity, five of which are already used in humans. The study has significant public health implications for prion disease treatment, particularly considering the absence of effective treatments.
The Kobe University study traced the HIV variant CRF01_AE to Thailand, where it emerged around 1977. The virus then spread through Southeast Asia and was introduced to Indonesia at least three times, with an Indonesian strain moving to Iran. Understanding these transmission trends is crucial for developing effective treatments.
Researchers in South Korea have detected the first hepatitis E virus from urban Norway rats, raising concerns about potential human transmission. The study found that 4.4% of examined rats carried the virus, which is linked to symptoms like fever, fatigue, and jaundice in humans.
A new study predicts climate change will lead to an overall decrease in areas suitable for malaria transmission from 2025 onwards. The research used several climatic and hydrological models to create a more in-depth picture of malaria-friendly conditions on the African continent.
Researchers at the University of Toronto have found a family of natural compounds that stall the unique metabolic process used by parasites to survive in the human gut. The discovery offers potential as new and more effective treatments for parasitic worm infections, which cause debilitating symptoms and developmental defects.
A study by UC San Diego researchers found that closing the US-Mexico border during COVID-19 increased HIV transmission due to continued drug tourism. The study analyzed data from participants who crossed the border, revealing nine new cases of HIV contraction primarily during the pandemic.
A new study from Wake Forest University School of Medicine found that school-entry requirements are linked to an increase in human papillomavirus (HPV) vaccinations. The study showed that these requirements, currently only implemented in a few states, can lead to higher HPV vaccination rates among adolescents.
Researchers found that increased CO2 concentrations prolong the life of SARS-CoV-2 variants in airborne particles, increasing transmission risk. Fresh air with lower CO2 levels can inactivate viruses faster, making opening windows an effective mitigation strategy.
A global genomic surveillance system using latest technologies and a 'One Health' approach can detect novel pathogens like avian influenza and antimicrobial resistance, catching epidemics before they start. This can inform vaccination campaigns, targeted treatments, and public health responses to prevent epidemics.
A study by Osaka University researchers found that mask-wearing behavior depends on the interplay of contextual changes and social norms. The results showed no significant relationship between system justification motivation and individual mask-wearing rates before or after the relaxation of governmental recommendations in March 2023.
Climate change exacerbates antimicrobial resistance by increasing global temperatures, sea levels, and disease transmission. This threat multiplier effect poses significant risks to human health, food supply, and ecosystem integrity.
Research found that babies born to mothers infected with dengue fever during pregnancy had lower birth weights and a higher risk of extremely low birth weight. Additionally, children whose mothers were infected had a increased risk of hospitalization from birth to age three, particularly in their second year of life.
Researchers used CRISPR-Cas9 to genetically modify kissing bugs, opening a door to controlling Chagas disease. The new method, ReMOT Control, allows efficient and targeted editing of genes in eggs.
A VACCELERATE Consortium survey study found that 57% of global infectious diseases experts ranked influenza as the top pandemic risk, with Disease X and SARS-CoV-2 also among the most concerning pathogens. The study highlights the need for continued preparedness and surveillance to prevent pandemics.
Researchers identified alterations in the monkeypox virus genome that correlate with increased transmissibility, shedding light on the 2022 outbreak. The study's findings may help develop more effective prevention and treatment strategies.
A new study found that gay and bisexual men who contracted mpox during the 2022 UK outbreak experienced substantial stigma and poor-quality care when accessing services. The research highlights the importance of involving affected communities in responses to outbreaks and improving quality of care for emerging infectious diseases.
A new implementation programme highlights challenges of locating and re-engaging former prisoners and individuals living with HIV who drop out of care. The study found that retaining these patients in care is crucial to end the global HIV epidemic.
A new UK/Portuguese study suggests that pets can act as reservoirs of resistance, spreading antibiotic-resistant bacteria to their healthy owners. The study found multidrug-resistant bacteria in both pet-owning households and among the owners themselves.
A new study highlights the critical role of hospital sinks in transmitting multidrug-resistant bacteria, with a pediatric ward outbreak showing even replacing all sinks didn't stop the contamination. The research emphasizes the importance of focusing on sinks and water-related areas to combat antibiotic resistance.
A computer program has been developed to aid in diagnosing mpox through electronic medical records, identifying patients at risk and prioritizing testing. The tool showed promising results, identifying nearly all cases of diagnosed mpox during the study period.
Scientists tested flood-control waterways near unsheltered encampments in Las Vegas, finding SARS-CoV-2 RNA in over 25% of samples. The study suggests a similar level of transmission among the unsheltered community as in the general population.
A new EU study has found that over-60s are six times more likely to acquire pneumonia-causing bacteria Streptococcus pneumoniae after daily contact with young children. Pneumococcal infections mainly affect children under two and the elderly, claiming almost two million lives worldwide every year.
A recent study has identified two distinct viral variants circulating in India, one with a low number of genetic variations and another with a high number of genetic variations. The latter variant is similar to LSDV strains from an outbreak in Russia in 2015, which may have contributed to the severity of the disease.
A team of researchers is using 'pathogen prospecting' to study archived mosquitoes for clues about malaria's history. By analyzing DNA from these specimens, they aim to reconstruct the disease's evolution and distribution, informing efforts to combat its ongoing threat.
Researchers developed a vaccine that significantly reduces TB transmission in cattle by almost 90%, improving prospects for disease elimination. The study's findings suggest that vaccinating calves could reduce the burden of disease in low- and middle-income countries.
A Danish study found that PrEP use was associated with a more than twofold increase in chlamydia, gonorrhea, and syphilis diagnoses. The researchers suggest that changes in sexual risk-taking may lead people to seek PrEP rather than increased risks.