Researchers propose new cross-view consistency losses to enhance self-supervision signal, achieving superior results in monocular depth estimation. The method leverages temporal coherence in depth feature space and 3D voxel space to mitigate the side effects of challenging cases.
A new machine-learning model using serum fusion-gene levels predicts HCC with an accuracy of 83-91%, significantly improving upon current biomarkers like serum alpha-fetal protein. This breakthrough tool may help identify patients at risk and monitor cancer recurrence, leading to improved survival rates.
Researchers at the University of Tsukuba found that using VR avatars with muscular bodies reduces pain perception by ~16%. The study also showed that matching the avatar's gender with the user's can further lower pain scores.
A study of over 1,200 children found a strong association between childhood sleep disorders and the development of attention deficit disorder (ADHD) symptoms. The research suggests that detecting sleep disorders at an early stage could help prevent or mitigate future ADHD symptoms.
Researchers have developed a new method in spectromicroscopy to investigate chemical species adsorbed on MXene surfaces and intercalated within the material. This technique, Scanning X-ray microscopy (SXM), enables high chemical sensitivity and has provided detailed insights into the chemical composition and structure of MXenes.
Researchers at Chapman University's Schmid College of Science and Technology discovered the 'internal concertina' strategy, used by hagfish to create u-shaped burrows. This burrowing behavior has significant ecological implications for sediment turnover and redox chemistry in marine habitats.
Astronomers found the earliest pair of quasars, revealing a bridge of gas between merging galaxies at 900 million years after the Big Bang. This discovery clarifies the role of galaxy mergers and black hole activity in the Universe's evolution.
A study of almost 400,000 live births found that paternal use of metformin monotherapy was not significantly associated with major congenital malformations. However, researchers noted that fathers prescribed metformin had higher rates of cardiovascular and metabolic conditions, which could affect reproductive health.
A decade-long study has discovered a vast untapped genetic potential in modern wheat varieties, revealing that at least 60% of the genetic diversity found in a historic collection is unused. This discovery provides an unprecedented opportunity to improve modern wheat and sustainably feed a growing global population. The study used a cr...
A team of scientists at Argonne National Laboratory has discovered that a lithium nickel manganese cobalt (NMC) oxide degrades rapidly with charge-discharge cycling due to changes in its lattice structure. This finding could lead to the development of lower-cost electric vehicles with longer driving ranges.
Researchers at Osaka University have developed systematically designed molecules that absorb near-infrared light but not visible light, paving the way for new applications in electronics. The new compounds show promise in areas such as solar cells, transistors, chemotherapy, and photodetectors.
A new study found that Americans are eating better, but disparities in diet quality persist among marginalized communities. The proportion of adults with poor dietary quality decreased from 48.8% to 36.7% between 1999 and 2020, while those with intermediate diet quality increased.
Researchers developed an emotion analysis model that can identify affective states with high accuracy using convolutional neural networks. The study shows that AI algorithms may be better at recognizing negative emotions than humans, but raises ethical concerns about data privacy and misuse.
A 246 million-year-old nothosaur vertebra was discovered on New Zealand's South Island, shedding new light on early sea reptiles from the Southern Hemisphere. The find reveals that these marine reptiles originated near the equator and rapidly spread to other regions, challenging long-standing hypotheses about their migration patterns.
A new AI-powered smartphone tool can detect stroke in seconds, improving diagnosis time and reducing permanent brain damage. The tool uses facial expression recognition to identify patients who need prompt treatment.
Researchers create special language Phenoscript to describe traits in a way that both humans and computers can understand. This allows for large-scale studies of organismal traits, boosting the emerging field of phenomics. The new language is being tested and aims to integrate semantic species descriptions with nanopublications.
A new study reveals specialized proteins can dramatically delay ice crystal formation in extreme cold, paving the way for impossible organ transplants. Cryogenic damage compromises cellular structures, leading to irreversible damage and organ failure.
Human papillomavirus (HPV) is a major cause of several cancers, with cervical cancer being the most prominent. Persistent infection with high-risk HPV types can lead to malignant transformation. Vaccination and screening programs are crucial in preventing HPV-related cancers.
Researchers at Johns Hopkins Medicine identified a potentially new biological target involving Aplp1, which drives the spread of Parkinson's disease-causing alpha-synuclein. The findings suggest targeting this interaction with drugs could slow Parkinson's disease progression and other neurodegenerative diseases.
A new method in neuroimaging analysis allows researchers to predict cognition and behavioral variables using smaller datasets, contrary to the long-held belief that thousands of participants are needed. The technique involves examining MRI data to find associations with behaviors and then applying predictions to an independent sample.
Researchers at Arizona State University found that human cumulative culture began to rapidly accumulate technological knowledge around 600,000 years ago. This allowed human populations to build on and recombine the solutions of prior generations, leading to complex solutions and organized institutions.
Researchers found that early forecast information sets the stage for how people react to subsequent warning messages, and authoritative sources can better engage at-risk community members. The study identified the most effective types of images in conveying hurricane risks, with the 'cone of uncertainty' being the most retweeted graphic.
A recent study by Mass General Brigham researchers found that adults with a family history of Alzheimer's disease on their mother's side had higher amyloid levels in their brains. This suggests that maternal inheritance may play a role in identifying individuals at heightened risk for developing the disease.
The introduction of Nile perch to Lake Victoria led to severe population loss and genetic bottlenecks in local cichlid species. The study reveals that four species experienced a 'bottleneck event' resulting in reduced genetic diversity, highlighting the devastating impact of exotic species invasion.
A group of scientists has released a first-of-its-kind list of bird species that haven't been seen in over a decade, using public media databases. The study found 144 species, mostly threatened with extinction, with most concentrated in Asia, Africa, and Oceania.
A new Australian study reveals widespread cyberbullying and sexual harassment in the esports industry, particularly affecting cis-gendered and trans-gendered women players. The study found that professional gamers are exposed to hostile behavior, which affects their mental health.
Leading academics recommend extending Sustainable Development Goals to 2050, addressing climate and biodiversity targets, and incorporating AI impact, community input, and inclusive consultations. They also suggest reforming global finance architecture and framing goals as missions with clear targets.
Finnish researchers found that blocking the DUSP6 protein can significantly improve treatment outcomes in experimental models by preventing dormant breast cancer cells from waking up. This discovery provides new insights into breast cancer recurrence and offers a potential basis for effective combination therapy.
Dorothee Dormann and Edward Lemke propose a new concept to measure the individual risk of getting age-related diseases by analyzing protein clumps in cells. This 'protein aggregation clock' could help diagnose age-related diseases at early stages or identify people at higher risk.
A new study reveals that US sexual health curricula are leaving LGBTQ+ students without essential information, leading them to seek advice from unreliable sources. Experts argue that addressing this negligence could be life-saving and urge policymakers to include LGBTQ+ content in curricula.
Researchers at Carnegie Mellon University have successfully integrated focused ultrasound stimulation into noninvasive BCIs, significantly boosting signal quality and enabling bidirectional brain-computer interfaces. The technology allows individuals to control a cursor or robotic arm using only their thoughts.
Researchers from University of Illinois and National Research Foundation are developing precision fermentation technology to convert sugars and inedible crop parts into nutritious food molecules. The project aims to improve food supply chain resilience, reduce environmental impacts, and address global micronutrient deficiencies.
A massive earthquake 2,500 years ago caused the Ganges River to change its course abruptly, affecting densely populated Bangladesh. The study suggests that a similar event could occur again in the future, with potentially devastating consequences.
A new model suggests that strong policies can backfire in polarized societies if people perceive low risk, leading to a rebound in fossil fuel use. In highly polarized situations, social interactions reinforce dominant norms, making it harder for subsequent transitions to occur.
Researchers found that toddlers with profound autism had larger embryonic brain cortical organoids (BCOs) compared to neurotypical controls. The BCO size was positively correlated with the child's later social symptoms, indicating that a larger brain may be the first sign of autism.
Researchers developed tricks to slow down the receptor's closure and speed up freezing process, capturing critical images of kainate receptor in open configurations. These images provide information for drug developers to design more precise medicines for patients.
Researchers in Brazil have developed bread with probiotic yeast that may help combat asthma by reducing airway inflammation and hyperresponsiveness. The bread's probiotic properties were shown to attenuate asthma symptoms in mice, suggesting potential for a new treatment approach.
The prevalence of chronic hypertension in pregnancy in the US more than doubled from 1.8% to 3.7% between 2007 and 2021, despite only 60% of those with the condition being treated with antihypertensive medications. This increase is linked to rising maternal age, obesity rates, and other factors.
A new atlas provides a detailed map of how cells and tissues age in roundworms, shedding light on the aging process and potential treatments. The study reveals unique aging features of different tissues and identifies key mechanisms underlying cellular aging.
Researchers developed a simple method to measure nano/microplastic concentrations in soil using spectroscopy, eliminating the need for separation processes. The method uses a wavelength combination of 220–260 nm and 280–340 nm to accurately quantify N/MPs in different soil types.
A recent study provides a comprehensive bibliometric analysis of the art market spanning 50 years, highlighting key trends and emerging themes. The analysis found consistent annual increase in research interest, significant shifts from hedonic art prices to topics such as artist branding and digital platforms.
Researchers at Francis Crick Institute develop a new genetic therapy that silences mutated NRAS gene in cells with congenital melanocytic naevus syndrome (CMN), potentially reversing debilitating giant moles. The treatment has shown promising results in mice and could be used to reduce cancer risk in affected children and adults.
Researchers developed a rapid genotyping test for patients with central nervous system lesions, detecting key mutations associated with brain cancers in samples taken during a lumbar puncture. The test eliminated the need for surgical brain biopsies in seven cases and significantly accelerated time to treatment, from an average of 12 d...
A study by Boston University School of Public Health found that over 1 in 10 FQHC patients experience major social risk factors such as food insecurity, housing insecurity, and financial strain. These challenges are significantly higher among FQHCs serving historically disenfranchised groups.
Researchers developed innovative reactor designs for CO2 capture using fly ash particles, achieving higher mineralization rates and efficiency. The study presents a promising approach to repurposing industrial by-products and reducing carbon emissions in coal-fired power plants.
The team gathered data that helps clarify the Crab Nebula's history, suggesting a weak iron core-collapse supernova as an alternative to electron-capture explosions. The study also mapped dust distribution within the nebula for the first time, revealing warmer dust in outer filaments and cooler grains near the center.
Researchers have developed a model to enrich sub-populations of cancer cells with high basal levels of mitophagy, promoting CSC features such as self-renewal, proliferation, and drug-resistance. This study highlights the importance of BNIP3/BNIP3L in maintaining cancer stem cell properties.
Researchers at Mass General Brigham developed a generative AI process that screens patients for clinical trial eligibility with high accuracy and reduced cost. The process, called RECTIFIER, was compared to traditional screening methods and found to be more accurate and cost-effective, with an estimated cost of $0.11 per patient.
Researchers discovered a new way to effectively treat melanoma using nutrients to reactivate suppressed metabolic pathways in cancer cells. The innovative treatment, involving tyrosine nanomicelles, showed promising results in mice and lab-derived human cells, inhibiting tumour growth and reducing glycolysis.
Researchers create a 3D printed vacuum system to trap dark matter, using ultra-cold lithium atoms to analyze the effects of domain walls. The team expects results within a year and believes this study will be an important step forward in understanding dark energy and dark matter.
Researchers discovered direct evidence of dairy product consumption and processing in the Pyrenees during the earliest stages of the Neolithic. Organic residues on ceramic vessels revealed a mixed economy with integrated agriculture and livestock farming.
Jupiter's Great Red Spot is a massive anticyclonic vortex with winds traveling at 450 km/h. The study reveals that the current GRS likely originated from a proto-GRS formed due to wind instability, which then underwent shrinkage over time.
The International Gemini Observatory and Subaru Telescope have discovered the most distant pair of merging quasars, seen only 900 million years after the Big Bang. The team used follow-up spectroscopy to confirm the nature of the quasar pair and their host galaxies.
Researchers are developing advanced electronic bandages to improve chronic wound monitoring and healing. These 'smart' dressings can sense and respond to changing conditions, providing continuous data on healing and potential complications.
Two studies by Prof. Lucía Chávez Gutiérrez's team reveal the role of gamma-secretase inhibition and amyloid plaque composition in AD. Aβ42 fragments impede gamma-secretase function, while multimodal mass spectrometry imaging reveals diverse plaque compositions.
A study comparing human hearts to those of great apes has found that the human heart is more streamlined due to higher demands for blood flow and thermal regulation. This suggests that human hearts may have evolved differently from their primate ancestors in response to unique ecological pressures.
Researchers at Virginia Tech have discovered a possible new pathway to treat colorectal cancer by targeting the NF-kB-inducing kinase (NIK) protein. The study, led by Irving Coy Allen, identifies changes in a significant signaling pathway in human patients and presents potential targets for therapeutics.
A randomized clinical trial found that both electronic cigarettes containing nicotine and varenicline were effective for 6-month smoking cessation. The study results suggest a potential new approach to smoking cessation.
A new study projects that global groundwater temperatures will rise by 2.1-3.5°C by 2100, impacting 77-588 million people's access to safe drinking water. Rising temperatures can also lead to increased concentrations of harmful substances and affect ecosystems.
Researchers found that KITLG upregulates COL4A1, leading to increased platelet activation and portal vein tumor thrombosis in hepatocellular carcinoma. The study highlights the critical role of the KITLG-COL4A1 axis in PVTT development.