A new mathematical model developed by Arizona State University researchers estimates how much of the calories people absorb from food, considering the role of gut microbes. The model, DAMM, suggests that short-chain fatty acids produced by gut microbes contribute to an average of about 140 calories per day.
A study by Harvard T.H. Chan School of Public Health found that gut microbiome alterations persist even after adenoma removal, increasing the risk of colorectal cancer. The researchers discovered that diet and physical activity were closely tied to CRC-associated gut microbes, suggesting lifestyle habits may contribute to sustained risk.
A large study of nearly 40,000 women found that plant-based diets with lower insulinemic potential can help women manage their weight and reduce the risk of obesity during menopause. Women who followed a diet rich in whole grains, nuts, legumes, and vegetables had a significantly lower risk of developing obesity.
Researchers at NIH have discovered key intracellular signaling processes involved in the weight-loss effects of semaglutide, a GLP-1 drug. The findings may help extend treatment duration and reduce plateaus experienced by patients.
A University of Waterloo study uses mathematical modelling to explore how Vitamin C affects digestion-related cancer risk. The research suggests that consuming Vitamin C-rich foods like leafy greens may decrease cancer risk, while taking supplements after meals could have a moderate positive effect.
A recent study found that consuming common preservative food additives increases the risk of high blood pressure and cardiovascular disease. Non-antioxidant preservatives, in particular, were linked to a higher risk of hypertension.
A low-calorie diet and behavioral support program significantly reduced weight in older patients with overweight and persistent atrial fibrillation at 8 months. The study found no safety concerns or impact on atrial fibrillation symptoms, cardiac remodeling, or need for further rhythm control interventions.
Polyendocrine Ovarian Syndrome (PMOS) impacts 13% of women, causing hormonal imbalance, insulin resistance, and chronic pain. Lifestyle interventions, particularly diet and exercise, show benefits for physical and mental health outcomes.
For at least 1,000 years, early herders in eastern Africa continued to fish, hunt, and gather alongside livestock, revealing a diverse diet that varied greatly from person to person. This strategy likely helped them adapt to a changing environment and ensured survival.
Weight loss followed by weight regain, known as 'yo-yo dieting,' is not supported by strong scientific evidence. The authors found that benefits of losing weight outweigh the theoretical risks of weight cycling in most cases. Repeated attempts at weight loss can provide meaningful periods of improved metabolic health and quality of life.
Two scientists, Dr. Anna Elizabeth Thalacker-Mercer and Dr. Rachel Whooten, receive awards for their groundbreaking research on micronutrients and muscle health in relation to aging and disease, as well as innovative approaches to childhood obesity care.
A study published in Aging Cell found that reducing dietary fat or animal-based protein can reduce 'biological age' in older adults. After just four weeks, participants showed significant reductions in biomarker profiles indicative of improved health and aging outcomes.
A review from Florida Atlantic University links obesity to Alzheimer's disease through disruptions in metabolism, highlighting the importance of mitochondrial function and gut-brain axis balance. Early detection and whole-body prevention may become possible through monitoring metabolic health.
A study published in the Journal of Nutrition found that moderate egg consumption is associated with a lower risk of Alzheimer's disease. Researchers discovered that eating one egg per day for at least five days a week reduces the risk of Alzheimer's by up to 27%.
A new study suggests that fitspiration content on social media can lead to negative self-esteem, unhealthy dieting, and exercise habits among young adults. Researchers analyzed 26 studies involving 6,111 individuals across seven countries, finding that even brief exposure to idealized images can trigger harmful comparisons.
A new randomized clinical trial shows that a low-fat vegan diet reduces greenhouse gas emissions by nearly three times more than a Mediterranean diet. The study also found significant improvements in key cardiometabolic outcomes, with the majority of environmental gains driven by eliminating meat, dairy, and eggs.
A new study published in Current Developments in Nutrition shows that adopting a low-fat vegan diet can rapidly reduce environmental impact while improving metabolic health. The 12-week randomized clinical trial found dramatic reductions in greenhouse gas emissions and cumulative energy demand.
A year-long study of NYC's East River used environmental DNA to reveal insights into urban wildlife activity, human food consumption and ecosystem health. The findings suggest that urban waterways can become continuous biosensors tracking biodiversity and habitat restoration outcomes.
A study by University of Pittsburgh researchers found that eating creates a temporary metabolic state that influences T cell function, leading to improved responses to infection. The findings have particular relevance for cancer immunotherapy and may inform when immune cells are collected or activated.
A study published in Nutrition, Metabolism and Cardiovascular Diseases found that plant-based dietary patterns were associated with significantly lower C-reactive protein levels compared to omnivorous diets. This reduction may indicate less background inflammation and lower cardiovascular risk.
A new review found that lifestyle behaviors like physical activity and diet can positively modulate the gut microbiome of cancer patients, but these effects are often influenced by non-modifiable variables. The study also highlighted the role of intrinsic patient characteristics in shaping microbial composition.
A comprehensive study reveals that high sodium intake, low fruit consumption, and lack of whole grains are the primary drivers behind 5.9 million cardiovascular deaths worldwide. Researchers emphasize the need for targeted policy interventions, such as mandatory front-of-pack labeling and food reformulation in high-population countries.
A new study found that FDA 'healthy' labels increase consumer selections of healthier snacks and command a price premium. The study, led by researchers at Oregon State University, examined consumer purchasing preferences for snack products with and without healthy labels.
A ketogenic diet has been shown to improve beta-cell function in patients with type 2 diabetes by decreasing proinsulin secretion and reducing pancreas stress. This improvement is associated with changes in the proinsulin-C-peptide ratio, a biomarker of pancreas stress.
A team of Kyoto University researchers found that exposure to high-fat diets induces persistent metabolic stress in killer T cells, but also discovered a pathway for protection through purine metabolism. By recycling xanthine, killer T cells can produce antioxidants to boost their ability to fight tumors.
A recent study found that adolescents consuming more ultra-processed foods have significantly higher odds of being overweight or obese. The study, which analyzed data from 155,000 adolescents across multiple countries, suggests that public health strategies should prioritize reducing UPF consumption among adolescents.
Researchers found a diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles. This increased intramuscular fat may increase the risk for knee osteoarthritis. The study suggests that addressing obesity and improving dietary quality are crucial to preserving muscle health.
A new study from Edith Cowan University found that higher sodium intake is associated with a faster decline in episodic memory in men. The study of over 1,200 participants suggests that diets high in salt may have broader cognitive impacts than previously understood.
Research in mice suggests artificial sweeteners can affect gut microbiome and gene expression, potentially impacting metabolic health. The study found that offspring of mice fed sucralose or stevia had altered gene expression linked to inflammation and metabolism.
A study by Princeton University researchers found that high-fat diets contribute to aggressive breast cancer growth, with tumors fed fatty acids forming hollow appendages. The team's 3D model showed that a ketogenic diet did not provide the expected benefits for this type of cancer.
A new study found that older men are more likely to reach for saltshakers than women, who's behavior is influenced by factors such as diet quality and lifestyle. The research highlights the importance of reducing salt consumption, particularly in industrialized foods.
A new study published in Aging-US found that plant-based dietary patterns are associated with slower epigenetic aging. The research analyzed data from two large cohorts and found that higher intake of plant foods was linked to decelerated biological aging.
Researchers discovered subtle changes in the blood can reveal early signs of cognitive decline caused by chemicals produced by gut bacteria. A blood test may one day transform how we detect dementia, potentially identifying people at risk years before symptoms appear.
Researchers discovered that placing fruit and vegetable sections near supermarket entrances increases purchased portions by 2,525 per week. This led to improved women's diets and potential long-term health benefits.
A new tool developed by UCL researchers can identify diet and nutrition misinformation, as well as its risk for potential harm. The tool assesses the content's risk based on factors like inaccuracy, hazardous omissions, and manipulative framing.
A new study from the University of Exeter found that children and teenagers are more open to vegetarian or vegan diets, but often struggle to keep it up. The study identified key reasons for this, including disgust at learning about animal meat sources, health concerns, and environmental issues.
Researchers found that metabolism of wheat fiber by intestinal bacteria generated bioactive anti-inflammatory metabolites, including polyphenols, which reprogrammed intestinal immune cells to suppress inflammation. The study suggests eating whole wheat foods may reduce one’s risk of developing inflammatory bowel disease (IBD).
A study of 10,978 participants found that cooking at home at least once a week is associated with a lower risk of dementia. Novice cooks with few culinary skills saw a 70% reduction in risk, while skilled cooks still benefited from regular meal prep
A systematic review of 31 studies found that diet changes and medications like thiazide diuretics, alkali therapy, and allopurinol may reduce stone recurrence in adults with calcium oxalate or calcium phosphate stones. However, evidence was generally limited, and more research is needed to confirm the effectiveness of these interventions.
Researchers found that people following a Mediterranean-style diet have higher levels of humanin and SHMOOSE, which are linked to protection against cardiovascular disease and neurodegeneration. The study suggests that specific components of the Mediterranean diet may directly influence mitochondrial biology.
A new study from Karolinska Institutet found that older people with a genetic risk of Alzheimer's disease who consume relatively large amounts of meat have a lower risk of cognitive decline and dementia. The study also shows that the type of meat is important, with a lower proportion of processed meat associated with a lower risk of de...
Researchers analyzed data from 2,500 US women and found that those consuming fewer ultra-processed foods had higher fertility rates. The Mediterranean diet showed a positive association with fertility, but this benefit disappeared once obesity was factored in.
Maintaining a healthy lifestyle, including a high-quality diet, moderate exercise, and low alcohol consumption, was associated with lower cardiometabolic disease risk. The study found that adhering to these healthy behaviors reduced the risk of major cardiometabolic diseases independent of medication use.
A UK study found that a 12-week ketogenic metabolic therapy program led to significant reductions in depression and anxiety scores. The program, delivered remotely, showed a 62% reduction in depression symptoms and a 46% reduction in anxiety, with 100% of participants completing the program.
A new review outlines the scientific explanations behind ketogenic diets' therapeutic benefits for epilepsy, including their ability to strengthen brain energy systems, reduce inflammation, and protect neurons. The review highlights the need for further research, particularly in adults, to develop new therapies that mirror the diet's e...
Researchers found that specific gut bacteria can sense diet and translate information into signals that tell fat cells to burn energy. A low-protein diet activated precise gut microbes that promote beige fat production, leading to improved glucose control and lower cholesterol levels.
Researchers found a high-fat diet accelerates tumor growth and invasion in triple-negative breast cancer, causing an increase in the enzyme MMP1. This dietary condition may lead to a poor prognosis and provide insight into tumor therapies.
A Pennington Biomedical researcher published an editorial on the benefits of fruit intake for vascular health, citing a study on increasing fruit intake with avocados and mangos. The findings suggest that diets rich in fruits can improve nutrient status and health outcomes, aligning with the goals of the Food Is Medicine initiative.
A new study by Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs Boston Healthcare System found that using GLP-1 receptor agonists in combination with adhering to healthy lifestyle habits significantly reduces cardiovascular risk among individuals with type 2 diabetes. The study showed that these two stra...
A ketogenic diet causes physical changes in brain cells that affect how they send information to one another, dampening the strength of signals between them. This quieter neural landscape might explain how the diet calms overactive electrical signaling characteristic of epileptic seizures.
Lifespan-extending treatments and dietary restriction have increased variance in age-at-death in vertebrates, failing to 'square the survival curve'. The findings highlight that current interventions do not equally benefit all individuals, leading to a biological lottery.
A new study by Ben-Gurion University of the Negev researchers found that repeated attempts at weight loss confer significant and sustainable health benefits over time, particularly through reduced visceral fat. Even when participants regain all the weight lost in a previous diet, their cardiometabolic health may remain improved.
A new study found that adding one avocado and a cup of mango to daily meals and snacks for eight weeks improved vascular function among adults with prediabetes, while also reducing diastolic blood pressure. The Avocado-Mango diet showed significant increases in flow-mediated dilation and nutrient-dense nutrients without changes in calo...
A study published in JAMA Neurology found that adhering to healthy dietary patterns, such as the DASH diet, is associated with lower subjective cognitive decline and better cognitive function. The findings highlight the importance of a balanced diet for maintaining long-term brain health.
A high-fiber diet has been linked to a reduced risk of coronary artery disease in night shift workers. The study, published in the European Journal of Epidemiology, found that consuming more fiber daily can lower the risk, with moderate intake recommended for those working night shifts regularly.
A new study suggests that a lack of fiber in the diet may impair emotional memory in older adults, linked to cognitive problems and inflammation. The amygdala, responsible for processing fearful experiences, is sensitive to highly processed diets, regardless of fat or sugar content.
Researchers discovered that pairing familiar plant-derived compounds can suppress inflammatory signals more effectively than using each compound independently. The study found that certain combinations increased the anti-inflammatory effect several hundred-fold compared to single ingredients alone.
Researchers identified 11 genetic regions influencing gut bacteria and roles they play, including connections to gluten intolerance, haemorrhoids, and cardiovascular diseases. The study analyzed genetic data from over 28,000 individuals, providing insights into the complex relationship between genes and gut microbiome.
A study from Lund University found that a climate-friendly diet rich in plant-based foods like wholegrains, legumes, fruit, and vegetables leads to better nutritional status compared to traditional diets. Despite lower meat consumption, most participants achieved sufficient amounts of key vitamins and minerals.
A new study found that versions of both diet patterns emphasizing healthy foods are associated with a lower risk of coronary heart disease. The study suggests that focusing on overall diet quality may offer flexibility for individuals to choose eating patterns that align with their preferences while still supporting heart health.