Articles tagged with Medical Facilities
Scientists at the University of Nebraska-Lincoln have successfully produced a drug compound featuring the 5P12-Rantes molecule, which could prevent HIV from attaching to human cells. The facility has delivered its first batch of the compound to Mintaka Foundation for formulation as a vaginal cream for clinical trials in South America.
Researchers at the Children's Medical Center Research Institute have identified a biomarker to accurately characterize mesenchymal stem cells (MSCs) in the body. This breakthrough finding could improve the success of clinical trials using MSCs for conditions such as bone fractures and osteoarthritis.
Researchers at UT Southwestern Medical Center have discovered that type I interferons can block the development of T helper 2 cells, which drive asthma and allergies. This finding offers new hope for treating allergic asthma patients by targeting this pathway.
Researchers at UT Southwestern Medical Center found that older adults prescribed thiazide diuretics are at a greater risk for developing metabolic-related adverse events. The study, published in the Journal of the American Geriatrics Society, suggests that these risks are common and warrant closer monitoring.
Researchers found that dialysis facilities in the Southeast have lower rates of kidney transplantation due to factors such as higher poverty levels and fewer staff. In contrast, Northeastern facilities had higher rates of transplantation, suggesting regional variations in access to care.
A study published in Cell Metabolism reveals that variations in the FTO gene indirectly affect the function of the primary cilium, a hair-like appendage on brain and other cells. This abnormality increases body weight by affecting leptin receptors, leading to increased food intake and obesity.
A research team at UT Southwestern Medical Center has identified the triggering mechanism of an atypical metabolic pathway that allows certain cancerous tumors to thrive. The discovery could provide a future target for drugs that would attack tumors relying on this reverse pathway for sustenance and growth.
A newly discovered gene called Samd4 plays a critical role in regulating metabolism, with abnormal distribution of fat and diminished insulin responses observed in the lean 'Supermodel' mouse. The study provides new potential avenues for research into diseases such as diabetes and obesity.
The National Institutes of Health has awarded $600,000 to the University of California, Riverside to expand its data storage capacity. This grant will enable researchers to process vast amounts of high-throughput data generated in various fields, including genome biology and biomedical sciences.
A Honolulu-based study reveals that shorter men tend to live longer, thanks to a protective form of the longevity gene FOXO3. This gene is linked to smaller body size during early development and lower blood insulin levels, resulting in a longer lifespan. The study, which followed over 8,000 Japanese-American men for nearly 50 years, p...
A study by Columbia University Medical Center researchers found that miniature neurotransmission regulates synapse development and contributes to the growth of synapses. The findings suggest that abnormalities in this process may contribute to neurodevelopmental diseases.
A new study reveals that even light drinking increases the risk of liver fibrosis in people co-infected with HIV and hepatitis C virus (HCV) infection. Researchers found a stark difference between co-infected and uninfected groups, highlighting the importance of counseling patients to reduce alcohol consumption.
A new study found that children treated at private clinics in sub-Saharan Africa are less likely to receive life-saving oral rehydration therapy, while poorer and rural children face significant disparities in care. The research estimates that closing the gap in care could save up to 20,000 lives annually.
Researchers at Liverpool University are developing new sensors to detect and measure nuclear radiation in the environment, aiming to locate radioactive sources with greater accuracy and sensitivity. The goal is to monitor sites, prevent releases, and support safe nuclear facility operation, with a focus on improving monitoring and cont...
Researchers use optogenetics to study skin cells called Merkel cells, which play a crucial role in sensing fine details and textures. The discovery may lead to the development of new prosthetics and treatments for skin diseases.
Frail elderly people living in residential care facilities are at increased risk of severe illness or death from viral gastroenteritis. Prompt notification of outbreaks to public health units led to a shorter outbreak duration.
A systematic review of 47 studies found that surveillance screening for hepatocellular carcinoma (HCC) in cirrhosis patients led to earlier detection, curative treatment, and longer survival. The pooled 3-year survival rate among screened patients was 50.8%, compared to 27.9% among unscreened patients.
The new guidelines recommend regular screening for pulmonary hypertension in SCD adults, and intensifying SCD therapy for those with PH. Patients with symptomatic PH should be treated, while management is guided by hemodynamic numbers obtained through catheterization.
Immunologists have developed an improved mass spectrometric method for proteomic analyses, allowing for the identification and quantification of more proteins. The new technique, called ISOQuant, eliminates the need for labeling samples, enabling direct analysis of patient samples and specific immune cells.
Two common procedures to treat pelvic organ prolapse without vaginal mesh are found to be comparable in safety and efficacy. Researchers also discovered that behavioral therapy did not improve urinary incontinence or prolapse symptoms in affected women.
Conscientious personality traits appear to be a key risk factor for better health, with participants who were more conscientious having lower rates of obesity, high cholesterol, and hypertension. Researchers suggest that incorporating personality assessments into preventive healthcare could lead to more effective care plans.
Scientists have successfully studied protein synthesis in adult stem cells, finding that precise protein production is essential to their function. The discovery opens up new avenues of cellular biology and may lead to a better understanding of diseases associated with protein synthesis mutations.
Researchers found that delaying the onset of decisions can improve response accuracy by allowing the brain to focus on relevant information and block out distractions. This mechanism is more beneficial than prolonging the decision process, which increases reaction times.
Researchers at Georgetown University Medical Center have discovered that a small region within the amygdala in bats is responsible for producing emotional calls and sounds. This finding may lead to new treatments for malfunctions in emotional responses, such as pathological aggression.
Veterans exposed to explosions may have brain damage despite lacking symptoms of traumatic brain injury (TBI), according to researchers at Duke Medicine. The study found comparable white matter damage in both groups, with no clear link between brain injury and cognitive problems such as reaction time or decision-making.
Research shows that one-third of young adults who survive a stroke are unable to live independently or need assistance with daily activities 10 years after their stroke. The type of stroke and subsequent recurrent strokes can also impact functional outcomes, highlighting the need for effective interventions.
Two NYU faculty members, Roozbeh Kiani and Nicholas Stavropoulos, have been awarded Sloan Foundation fellowships for their innovative research in neuroscience and sleep. Their work has the potential to lead to new medical interventions for mental and cognitive disorders and improve understanding of human sleep and its regulation.
The FASEB MARC Program has announced seven travel awards totaling $12,950 to support students and scientists from underrepresented groups at the Association of Biomolecular Resource Facilities (ABRF) 2014 annual meeting. The program aims to increase diversity in biomedical research.
Gregg Semenza discovered the oxygen-sensing gene HIF-1alpha, a master regulator of cellular response to low oxygen levels. His work has led to translational studies enhancing oxygen and blood flow in conditions like cardiovascular disease and cancer.
A recent study published in the Journal of Investigative Medicine found that gastric banding patients often fail to meet daily nutrient requirements despite supplements and counseling. To maintain health after bariatric surgery, patients are advised to consume more protein-rich foods, include fatty fish, and limit processed foods.
A study at UT Southwestern Medical Center found elevated levels of DDT metabolite DDE in patients with Alzheimer's, suggesting a link between DDT exposure and the disease. The study suggests that early biomarkers could help predict Alzheimer's development due to DDT exposure.
A study by Columbia University Medical Center researchers identified matrix metalloproteinase-9 (MMP-9) as a key factor contributing to motor neuron degeneration in amyotrophic lateral sclerosis (ALS). The findings suggest that MMP-9 inhibitors may offer a new therapeutic option for treating this incurable neurodegenerative disease.
A new study found that tag plays at home plate have the highest injury rate in professional baseball, occurring 4.3 times more often than other base-running plays. The researchers suggest adopting the collegiate rule to reduce collisions and protect both catchers and baserunners.
A study of geriatric health care professionals found they experience emotional struggle while caring for their own aging relatives, but also benefits from this dual role. The researchers emphasize the need for support and tools for all caregivers to navigate difficult conversations with providers and family members.
New study finds less gray matter in dyslexic brains is a consequence of poor reading experiences, not the root cause. The research suggests that experience-induced changes in the brain may be responsible for cognitive impairment in dyslexia.
The US Army's new strategic research plan aims to improve treatment outcomes for traumatic brain injury by identifying critical research priority areas. The report highlights six main target areas, including pharmacological interventions and preclinical drug assessment.
A UT Southwestern Medical Center study found that blocking immune system molecule interferon-gamma (IFN-γ) and matching major histocompatibility complex (MHC) genotypes can improve corneal transplant acceptance rates in mice. The strategy enhances long-term graft survival, almost guaranteeing success.
Researchers used high-resolution fMRI to identify where Alzheimer's disease starts, spreads from the lateral entorhinal cortex (LEC) to other areas of the cerebral cortex. LEC dysfunction occurs when changes in tau and amyloid precursor protein (APP) co-exist, damaging neurons that then spread to adjoining regions.
Dr. Richard Bruick receives the 2014 Edith and Peter O'Donnell Award for his work on cellular responses to maintain oxygen and iron homeostasis. His research has the potential to improve treatments for anemia, renal cancers, and iron overload disorders.
The CompGen initiative brings together top faculty in genomic and computational sciences to analyze trillions of nucleotides and better understand the human genome. The facility will enable more accurate and efficient analysis of DNA, incorporating visualization components to visualize genetic data in real time.
The Edinburgh Genomics facility will focus on large-scale studies of genetic code, aiming to develop therapies tailored to patients' genes. Scientists will also explore the impact of genetics on animal wellbeing and crop disease in agriculture.
Researchers at Intermountain Medical Center Heart Institute discovered a link between high RDW levels and increased risk of depression in heart patients. Elevated RDW is associated with poor outcomes, including heart attacks and death, and may indicate anemia or other underlying conditions.
Researchers at KIST developed a biodegradable magnesium alloy that can be used in orthopedics and plastic surgery. The alloy has been approved for clinical testing and is expected to reshape the landscape in fracture treatment.
Researchers found that individuals with low mindfulness scores performed better on tasks requiring implicit learning, suggesting that mindfulness can prevent the development of automatic habits. This finding implies that mindfulness may help individuals avoid forming both positive and negative habits through unconscious processes.
A recent animal study from Georgetown University Medical Center suggests that 'cold turkey' withdrawal from morphine can trigger a decline in mental health. Researchers found that treating addicted animals with morphine both increased protective CCL5 protein and decreased pro-inflammatory cytokines, suggesting a beneficial effect.
A new study analyzes injuries to children under 7 years old born to teenage parents, revealing a significant risk of falls and ingested objects. The study emphasizes the need for injury prevention programs focusing on home safety and parental supervision skills to mitigate these risks.
Researchers correctly identified the brains of mathematician Carl Friedrich Gauss and medical scholar Conrad Heinrich Fuchs using MRI scans, revealing they were switched over 150 years ago. The discovery highlights the importance of historic collections for modern-day research.
Military veterans who struggle with managing their finances are at a higher risk of becoming homeless. A new study published in the American Journal of Public Health found that money mismanagement is a significant predictor of future homelessness among veterans, regardless of income or mental health status.
Researchers at Georgetown University Medical Center discovered a compound derived from cruciferous vegetables can protect rats and mice from lethal radiation doses. The compound, DIM, also showed potential in preventing or mitigating sickness caused by radiation exposure.
A study by BUSM found that the majority of family medicine residency program directors believe complementary and alternative medicine (CAM) is essential for resident training, but few have specific learning goals or adequate evaluation methods in place. The study also highlighted significant differences between strong and weak CAM/IM p...
A research campaign aimed at increasing organ donor registrations showed a statistically significant increase in the number of people registering to donate. The campaign, which used multiple messages and volunteers, was implemented at 20 Department of Motor Vehicles facilities in Illinois.
A study by Simon Fraser University researchers found nearly 40% of seniors who fall experience head impact, with linoleum or tile flooring being the most common cause. The team suggests designing safer environments, improving procedures for detecting brain injuries, and promoting strengthening exercises to reduce falls.
Dr. Südhof's pioneering work on synaptic transmission has led to a better understanding of brain function under normal and pathologic conditions, such as Alzheimer's disease. He was recognized for his discoveries of key information about cellular transport systems, alongside Dr. James E. Rothman and Randy W. Schekman.
A study found that using electronic health records (EHRs) for patients with diabetes resulted in a modest reduction in emergency department visits and hospitalizations. However, EHR implementation did not affect office visit rates.
A new study from Wake Forest Baptist Medical Center shows that community-supported agriculture (CSA) programs can increase fresh fruit and vegetable access in under-resourced communities. The program provided participants with a weekly box of produce and educational sessions, resulting in increased consumption and satisfaction.
A study at Columbia University Irving Medical Center identifies RbAp48 as a significant contributor to age-related memory loss, which can be reversed. The researchers found that RbAp48 plays an active role in the process and propose it as a target for therapeutic intervention.
Jeffrey M. Hausdorff, PhD, receives the GSA's Excellence in Rehabilitation of Aging Persons Award for his work on gait variability, motor-cognitive interactions and the assessment of fall risk. His research has led to the development of innovative rehabilitation programs, including a multi-modal treadmill training program that improves...
A new study found that people experiencing sudden cardiac arrest at exercise facilities have a higher chance of survival than at other indoor locations. The study looked at 849 cases in Seattle and King County, Wash., and found that traditional exercise facilities had the highest survival rates.
A recent study reveals that many people experience mental health disorders after disasters, with nearly 1 in 3 showing signs of PTSD. The study emphasizes the need for a consistent and integrated system for identifying, triaging, and treating these individuals.
A study at Columbia University Irving Medical Center identifies key molecular pathways leading to late-onset Alzheimer's disease. The research highlights several new potential drug targets, including SV2A and RFN219, which are involved in the processing and trafficking of amyloid precursor protein.