A large-scale international study has identified epigenetic changes in DNA methylation at nearly 200 genomic loci associated with being overweight. The study found significant changes in the expression of inflammatory genes and potential epigenetic markers for type 2 diabetes risk.
Research published in Thorax found a significant association between high dietary processed meat intake and worsening asthma symptoms. Participants who consumed four or more weekly servings of cured meats experienced the greatest worsening of symptoms.
A study of Israeli adolescents found that higher BMI in late adolescence and long-term cumulative burden of BMI predict poorer cognitive function later in life. Taller stature was associated with better global cognitive function, independent of socioeconomic position.
A study found that higher body mass index (BMI) and fat mass are significant markers of risk for stress- and urgency urinary incontinence (SUI and UUI) in older women. Women who lost at least 5% of their BMI or fat mass were less likely to experience new or persistent SUI over a three-year period.
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A study published in the Journal of the American College of Surgeons has identified obesity-induced lymphedema as the cause of massive localized lymphedema. A new probability scale can help physicians identify patients at greatest risk for this condition, recommending weight loss as the preferred initial treatment.
A study of English schoolchildren found that the London 2012 Olympics inspired many to try new sports and activities, but levels of physical fitness worsened. Despite positive associations with increased activity and lower BMI among some participants, overall cardiorespiratory fitness declined significantly after the event.
Researchers found that fat-free mass index, but not body mass index, was a significant predictor of survival in patients with idiopathic pulmonary fibrosis. Lower fat-free mass index was linked to worse survival over an average follow-up of 2.3 years.
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Researchers used brain-machine interface training to investigate phantom limb pain and found that changes in cortical plasticity, rather than motor function, are key to reducing pain. This approach shows promise for treating chronic pain conditions, including phantom limb pain and residual surgery pain.
A study of over 60,000 births in South Australia found that women conceived in winter are more likely to develop gestational diabetes during pregnancy. This seasonal variation has implications for both child and mother health.
A new study published in Pediatrics found that children who skip breakfast and have irregular sleep patterns are more likely to become overweight or obese. The research, based on data from over 19,000 UK children, highlights the importance of early life factors such as smoking in pregnancy and disrupted routines in predicting weight gain.
High physical fitness increases ALS risk before age 45, while individuals with high IQs have increased risk at 56+ years. Individuals with lower BMI (25+) show reduced risk across all ages.
A new study finds that overweight and obesity rates among young children increase significantly during summer vacations, not during the school year. The study, which analyzed data from over 18,000 children, suggests that major risk factors for child obesity lie outside of schools.
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Reducing exposure to environmental synthetic chemicals by 25% could ward off over 150,000 new cases of diabetes in Europe and save €4.5 billion every year. A 40% reduction in BMI would lead to a 40% decrease in diabetes prevalence among 70-75 year olds.
A study found that mothers with higher BMI before pregnancy have shorter telomeres in their newborns, indicating a link between maternal weight and biological age. This association may increase the risk of chronic diseases in adulthood.
Professional baseball players have seen a significant increase in weight and obesity over the last quarter century. The majority of athletes were within the normal BMI range for over 100 years, but around 1991, their average BMI began to rise, with nearly 80% now falling into the overweight or obese category.
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Research reveals that even marginal increases in weight negatively impact female job prospects in service sector jobs. Workplace discrimination against those of 'normal' weight is not new, but women face greater bias, highlighting unrealistic societal expectations and practical implications for employers.
A study published in Neurology found that excess weight in women increases the risk of ischemic stroke, while decreasing the risk of hemorrhagic stroke. The research followed over 1.3 million women for 12 years, revealing a significant association between body mass index and stroke subtype.
Overweight women and underweight boys are at higher risk of asthma hospital admissions in early adulthood. The study analyzed data from over 300,000 schoolchildren and found a significant link between childhood BMI and adult asthma admissions.
A longitudinal study of extreme preemies born between 1977 and 1982 found that they are four times more likely to develop dysglycemia than normal birth weight peers. By their early 30s, 26% of ELBW babies have abnormal blood glucose levels.
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A study published in American Journal of Public Health found that using stand-biased desks in classrooms for two consecutive years reduced the BMI percentile of children by 5.24%. The study, conducted over a two-year period, involved 193 third- and fourth-grade students at three Texas elementary schools.
A randomized controlled trial in Brazil found that a school intervention costing less than 20 cents per child stopped unhealthy weight gain and increased fruit consumption. The intervention promoted physical activity, healthy eating habits, and reduced BMI in children.
A global study involving 10.6 million people contradicts a previous finding that being overweight increases longevity, stating that it is instead linked to a higher risk of premature death from coronary heart disease, stroke and respiratory disease. The study's findings have important clinical and public health implications.
A Kaiser Permanente study found an increased risk of becoming overweight or obese among normal-weight 18-year-olds living in neighborhoods with lower education or income levels. Over four years, 25% of these young adults became overweight or obese.
A clinical trial found metformin to be effective in reducing weight gain associated with atypical antipsychotics in children and adolescents with autism spectrum disorder. The study, published in JAMA Psychiatry, suggests that metformin may offer a potential treatment option to mitigate the risks of diabetes linked to weight gain.
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A study published in the American Journal of Public Health found that stand-biased desks can lower BMI in elementary school children, with a three percent drop on average. The intervention was shown to be effective across demographic groups, regardless of age, gender, or race.
A UCLA study found that a healthy diet, regular physical activity, and normal body mass index can lower plaque and tangle levels in the brain. Lifestyle factors such as a Mediterranean diet were shown to directly influence abnormal proteins in people with subtle memory loss.
A new study reveals that China is facing a significant increase in cardiovascular disease cases due to factors such as high blood pressure, obesity, and an increasingly sedentary lifestyle. The study found that these risk factors are associated with a substantial burden of heart attacks and strokes in the Chinese population.
A study of monozygotic Swedish twins found that higher BMI was associated with increased risk of diabetes, but not heart attack or death. The results suggest that interventions promoting weight loss may be more effective in reducing diabetes risk than cardiovascular disease and mortality.
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A study found an association between lower body mass index and greater deposits of Alzheimer's-associated protein beta-amyloid in the brains of older individuals, particularly those carrying the APOE4 gene variant. This may indicate that being underweight late in life increases the risk of developing Alzheimer's disease.
A study of Swedish twins found no association between higher BMI and increased heart attack risk, but a greater risk of developing type 2 diabetes. The results suggest that interventions targeting weight loss may be more effective in reducing diabetes risk than cardiovascular disease risk.
A study of 4,046 genetically identical twin pairs found that higher Body Mass Index (BMI) is associated with an increased risk of type 2 diabetes but not heart attack or mortality. The research, published in JAMA Internal Medicine, suggests lifestyle changes may be less effective against cardiovascular risks than previously thought.
The study found that genetic signatures predict education, height, BMI, and heart disease more strongly today than in the past. The role of genes decreased for education but increased for BMI and heart disease due to environmental factors.
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A recent study identified a genetic variant associated with higher BMI levels and increased efficiency of fat storage among Samoans. This 'thrifty' variant, found on chromosome 5, is linked to the islands' high obesity rates and may have evolved as an adaptation to food scarcity in ancient times.
A large study of nearly 21,000 people in Jilin Province found that being overweight or obese was associated with regular meat consumption, having ever been married, and getting less than 7 hours of sleep per night. The prevalence of obesity and overweight was higher among older adults, particularly those aged 55-64 and 65-79.
A new study from Duke University found that infants born to obese mothers were 8% larger during the first two years of life compared to those born to healthy-weight mothers. The study also showed a link between maternal weight gain during pregnancy and infant size.
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A study of 3,302 women transitioning through menopause found associations between VMS patterns and demographic, reproductive hormone, and psychosocial factors. Women with early onset VMS were more likely to have elevated depressive symptoms and poorer health.
A large international study found that being overweight or obese significantly increases the risk of dying prematurely, with a BMI of 40.0-<60.0 kg/m2 associated with nearly three-fold risk.
A study of 3.9 million adults found that obesity is associated with an increased risk of premature death, with the greatest effect in men. The risks of coronary heart disease, stroke, respiratory disease, and cancer are all increased, resulting in a three-fold greater excess risk of premature death among men compared to women.
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A new study from Tufts University researchers shows that the average weight of offensive linemen in Division III college football conferences has increased nearly 38 percent since 1956. The study highlights the need for post-football lifestyle changes to prevent long-term health complications and emphasizes the importance of helping at...
Researchers discovered that inadequately hydrated obese individuals tend to have a higher BMI, suggesting water intake plays a crucial role in weight management. The study also highlights the importance of staying hydrated for overall health regardless of body mass index.
Standard BMI may underestimate global obesity levels by over 400-500 million, particularly in East Asian populations with slimmer builds. Researchers propose adjusting BMI cutoffs for basal slenderness to better estimate obesity and undernutrition rates worldwide.
A high BMI in youth increases the risk of heart failure, even after adjusting for recent weight changes. Stable weight throughout life may be the best approach to reduce this risk. Excessive weight at a young age puts individuals at a far higher risk of heart failure compared to maintaining a healthy weight.
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A recent study published in the European Heart Journal found that teenage body weight is a significant predictor of heart failure risk in adulthood. Men with a BMI of 20 or higher had a significantly increased risk of heart failure, with the risk rising steeply with increasing body weight.
Research of over 1.6 million Swedish men reveals that being overweight as a teenager significantly increases the risk of heart failure in early middle age. The study found a nearly ten-fold increased risk for those with a BMI of 35 or more, emphasizing the importance of maintaining a healthy weight from an early age.
A 40-year study of nearly 45,000 Swedish men found that being overweight in late adolescence significantly increases the risk of developing severe liver disease later in life. The study adjusted for various confounding factors and found a 64% increased risk for overweight men compared to those with low normal weight.
A study found that breastfeeding for a long duration was associated with lower rates of postweaning antibiotic courses and decreased body mass index (BMI) in later childhood. The benefits may be attributed to the development of intestinal microbiota, which is dependent on an infant's diet.
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Researchers found higher levels of saturated fatty acids and lower levels of monounsaturated fatty acids in the breasts of postmenopausal women with invasive ductal carcinoma. This may indicate a new risk factor for breast cancer.
A new study from the Cornell Food & Brand Lab found that women who recall their parents commenting on their weight are more prone to being overweight and less satisfied with their weight as adults. Commenting on a daughter's weight can have a negative impact later in life, damaging body image regardless of weight.
A recent study found a small rise in obesity prevalence among US teenagers over the last 25 years, with a notable increase in adolescent obesity between 1988-1994 and 2013-2014. Obesity rates have decreased among younger children but plateaued for older kids before rising again.
People driving over an hour a day are 2.3kg heavier and 1.5cm wider around the waist compared to those who drive less frequently. Men are more likely to experience weight gain due to prolonged car travel, according to research by Australian Catholic University.
A large European study found that higher body mass index (BMI) and waist circumference are associated with an increased risk of high-grade prostate cancer. Men with greater adiposity have a higher risk of aggressive forms of the disease, highlighting the importance of maintaining a healthy weight.
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Researchers found that women face a range of barriers to physical activity, including physical challenges and psychological concerns, which vary by weight. A new study suggests that a one-size-fits-all approach may not be effective in helping women become more physically active.
A whole-person perspective is needed to accurately assess obesity severity, considering factors like muscle mass and ethnicity. The review article suggests staging obesity treatment from stage 0 to stage 4, with intensive lifestyle modification being crucial for preventing disease progression.
Severely obese children are more likely to be ostracized and show signs of depression in first grade, according to a new study. The research found that these children were frequently teased and rejected by peers, leading to emotional health issues.
A five-week middle school obesity prevention program called Students for Nutrition and eXercise (SNaX) helped obese students lose weight over a long term, with an average reduction in body mass index (BMI) of about nine pounds. The program combined environmental changes and peer-led education to promote healthy eating and physical acti...
Researchers found simultaneous changes in response to obesity in almost all tissues studied, including the digestive system and internal organs. The study highlights the burden of overweight and obesity on these systems and may lead to personalized care.
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Researchers found that participants with the top quartile of baseline fitness experienced the least annual decline in pulmonary function. Sustained or improved fitness was also associated with the least decline in lung function over 20 years, regardless of obesity and smoking status.
A new 20-year study shows that higher levels of cardiorespiratory fitness significantly reduce the risk of developing prediabetes or diabetes. The research found an 8-11% increase in fitness level to be associated with a 0.1% lower risk, highlighting the importance of exercise programs for reducing these conditions.
A study published in JAMA found that the BMI value associated with lowest all-cause mortality has increased by 3.3 points over three decades, from 1976-1978 to 2003-2013. The risk for all-cause mortality decreased among obese individuals, with an optimal BMI of 27 or greater found in recent cohorts.
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Research reveals a decrease in excess mortality risk associated with obesity since the 1970s, with normal weight individuals now facing higher mortality rates. The study's findings suggest revising overweight categories based on updated data.