Articles tagged with Human Physiology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent MSU study has discovered that many preclinical models of human breast cancer can replicate several key characteristics, particularly at the gene level. The researchers analyzed 1,172 mouse mammary tumor samples from 26 different models and found that most human breast cancers can be represented by one specific strain of mice.
Associate Professor David Newman is a world leader in aviation medicine, receiving the 2014 John Paul Stapp Award for his work in aerospace biomechanics. He has made significant contributions to the field of aviation safety, focusing on pilot fitness and aviation-related health issues.
Researchers discovered a protein responsible for gas exchanges in zebrafish gills, which may mimic human kidney function. NHE3 protein controls sodium and hydrogen ions, aiding in energy-saving balance and waste removal.
Joan Chiao's research investigates how cultural factors influence basic psychological and neural processes underlying social behavior and emotion processing. The study focuses on the physiological and cultural foundations of traits such as empathy and altruism, shedding light on their role in shaping human social interactions.
Researchers have identified a specific protein involved in mediating the skin's response to UVR and found that the signal transduction cascade resembles a light-activated pathway in the eye. This new insight into the molecular pathway underlying UVR detection could lead to improved sun protection methods.
The Wyss Institute will use its Organs-on-Chips technology to test human physiological responses to radiation and evaluate drugs designed to counter those effects. The project aims to improve the national ability to respond to nuclear radiation incidents and reduce animal testing.
A team of biomechanics experts at SMU are investigating the forces involved in typical basketball collisions and their relationship to balance and body control. The research aims to estimate 'flopping' forces from video data and potentially enhance video reviews of alleged flopping.
Physiology's enduring relevancy is highlighted through Dr. Joyner's research on complex bodily functions like blood pressure and blood flow during exercise. The redundancy in human systems complicates genetic explanations for diseases, leading to a comeback of multi-directional thinking in physiology
The collaboration aims to accelerate the translation of Organs-on-Chips from benchtop to marketplace, providing more predictive and useful measures of drug efficacy and safety in humans. The Wyss Institute has developed over ten Organs-on-Chips, including lung, heart, liver, kidney, bone marrow, and gut-on-a-chip technologies.
Researchers found that high school athletes experienced compromised focus and task-switching abilities for up to two months after brain concussions. The study's findings suggest that athletes may need longer recovery periods than current practices dictate to minimize the risk of subsequent concussions.
The Wuzhishan miniature pig genome sequence has provided valuable knowledge for medical engineering and drug design. Despite high levels of polymorphism, the genome is mostly homozygous, with 84% homology between humans and pigs.
Researchers found that motor unit firing patterns varied significantly across the menstrual cycle, with a significant increase in the late luteal phase, potentially affecting joint stability and injury risk. The study suggests that hormone fluctuations may play a role in knee injuries among female athletes.
A recent study on rhodopsin in Xenopus rod photoreceptor cells reveals that the geometry of micro-compartments formed by incisures affects its signaling. The researchers found that boundary geometry, rather than heterogeneity in diffusion or bound fraction, explains differences in rhodopsin distribution
A study published in the American Journal of Physical Anthropology found that singing gibbons use the same vocal techniques as professional soprano singers. The research reveals a physiological similarity between gibbon and human voices, suggesting that complex vocal abilities evolved in humans were not due to unique modifications.
The Wyss Institute is developing an automated instrument that integrates 10 human organs-on-chips to study complex human physiology outside the body. This will accelerate assessment of drug safety and efficacy, informing regulatory decision-making.
Research reveals that king penguins in areas with daily human disturbance show less stress from noise and approaching humans, but experience increased heart rate after capture. The study emphasizes the importance of considering human presence effects on ecological studies and conservation measures.
A new study funded by the California Raisin Marketing Board found that eating raisins as an after-school snack prevents excessive calorie intake and increases feelings of fullness. The three-month study among normal-weight children ages 8-11 showed significant benefits from snacking on raisins.
Researchers at Harvard's Wyss Institute have created a living human gut-on-a-chip that mimics the structure, physiology, and mechanics of the human intestine. The device supports the growth of living microbes and could help understand intestinal disorders such as Crohn's disease.
University of Missouri nutrition experts recommend eating balanced meals and farm-fresh produce to promote healthy eating choices. Families can implement healthy eating ideas by trying seasonal fruits and vegetables, such as those available at local farmers markets or grocery stores.
Research by Berthelot and Len found that athlete performance follows an exponential growth curve to a peak before declining irreversibly between the ages of 20 and 30. This pattern is also observed in other physiological parameters such as lung function and cognitive skills, suggesting a universal law governing human capability evolution.
A recent study published in the Journal of Biological Chemistry suggests that vitamin A plays a more direct role than previously believed in various physiological functions. The study found that vitamin A itself is active in activating nuclear receptor TR4, which plays roles in sperm cell production, lipid regulation, and central nervo...
Physiologist E. Paul Zehr uses Batman as a framework to discuss exercise and physical training, illustrating how the body responds to physical discipline. His approach connects science to popular culture, helping students understand physiology better.
Researchers found that heat acclimation provided significant benefits for athletes competing in cool weather, including improved aerobic performance. The study's findings suggest that heat acclimation could be a practical and effective approach to improve athletic performance in cooler conditions.
A Spanish research team has created a system that measures human physiological parameters and uses them to control virtual character behavior in real-time. The goal is to create a more immersive experience by tapping into the unconscious mind.
A recent study led by the University of Colorado at Boulder found that upgrading a wastewater treatment plant in Colorado has mitigated the problem of male fish becoming feminized due to chemical contaminants. The team observed no effects on male sex characteristics after 28 days of exposure to effluent water, contradicting previous fi...
The study provides strong evidence that the NBD dimer does not fully dissociate in each gating cycle, proposing a new gating model for CFTR with two distinct cycles. This advancement sheds light on the chloride channel's behavior and may lead to improved treatments for cystic fibrosis patients.
A new study published in the Journal of Applied Physiology suggests that human running speeds can exceed 28 mph due to limitations imposed by muscle fiber contractile speed. Researchers found that elite sprinters' foot-ground contact times are brief, implying a biological limit on how quickly muscles can generate forces.
A meta-analysis of 134 studies involving over 3,400 participants found that men's brain and body responses were more aligned during sexual arousal. In contrast, women's mind-body responses were less consistent. The study suggests significant gender differences in how people experience and respond to sexual stimuli.
A meta-analysis of 134 studies involving over 3,400 participants found that men's subjective and physiological measures of sexual arousal were more closely matched than women's. The researchers identified two methodological differences - the type of stimuli and timing of assessment - that may contribute to this gender difference.
Researchers charted microbial communities across the human body, finding unique and diverse populations in different regions. The study suggests that personalized microbial communities vary widely from person to person and could hold key insights into human health.
Heat waves pose a significant threat to older adults and individuals with chronic diseases, who are more susceptible to heat-related illnesses due to impaired thermoregulation. Air conditioning and working fans can reduce the risk of mortality by up to 80% and 30%, respectively.
A new study from the University of Missouri suggests that high-impact activities like running can have a greater positive effect on bone mineral density (BMD) than resistance training. The research found that runners had greater spine BMD than cyclists, and that high-impact activity may override the benefits of lean body mass on BMD.
Researchers at Caltech have created images of the heart's muscular layer showing a connection between muscle configuration and contraction. The findings provide evidence that the helical shape is crucial to the heart's effective beating, settling a 50-year debate.
Researchers investigated physiological methods used by well-trained runners to control exercise intensity and avoid exhaustion. They found that heart rate response scales with race distance, indicating athletes actively manage their body's increasing strain.
Researchers have discovered that Tabebuia extract can delay dietary fat absorption in animal models, reducing triglyceride levels. The extract's potential use in treating obesity and associated diseases like type 2 diabetes and coronary heart disease is being explored.
A human clinical study by Montana Center for Work Physiology and Exercise Metabolism found that wildland firefighters who consumed a yeast-based antioxidant supplement, Wellmune WGP¹, had significantly fewer upper respiratory tract infections compared to a placebo group. The study showed a strong statistical trend of 23% fewer infectio...
Researchers at University College London used a virtual human simulation to predict the effectiveness of an HIV drug against resistant mutations. The study could lead to tailored treatment approaches for patients developing resistance to their drugs.
Mice fed human diet exhibit distinct liver gene expression profiles compared to those on a chimpanzee diet, suggesting dietary influences on physiological differences between humans and other apes. This study replicates previous findings in mice fed different diets.
Researchers explore how genes, neurotransmitters, and brain function impact athletic performance and endurance. Studies reveal that certain genetic variations and mental state can significantly enhance physical abilities.
A new study finds that daylight saving time (DST) significantly disrupts the human circadian clock's seasonal adjustment. Researchers analyzed sleep patterns of over 55,000 people in Central Europe and found that DST timing fails to adapt, leading to significant disruptions in daily rhythms.
Researchers discovered that specific genetic variants of an odor receptor determine how people perceive pleasant or unpleasant odors. The study focused on two sex steroid-derived chemicals and found that different genetic variations led to varying reactions.
Researchers at EMBL have identified a molecule called n-cofilin crucial for preventing neuronal disorders. The protein helps organise cell skeleton, essential for brain development and function.
A recent study using spontaneously hypertensive rats found that testosterone supplements promote renal injury and exacerbate hypertension in aging male rats. The research suggests that natural decrease in testosterone levels with age may affect the progression of cardiovascular/renal disease in men taking testosterone replacement therapy.
A recent study conducted by University of California - San Diego researchers found that using a Taser on healthy individuals does not cause lasting harm. The study monitored the physiological effects of a single Taser activation in human subjects and discovered no clinically significant or lasting changes.
Preliminary results of Taser exposure on healthy subjects revealed no clinically significant changes in cardiovascular and blood parameters after a single 5-second exposure. The study measured systolic and diastolic blood pressures, heart rate, calcium, sodium, potassium levels and blood pH in 32 subjects.
Researchers at Massachusetts General Hospital found that patients and therapists share similar physiologic responses during moments of high positive emotion, leading to higher ratings of therapist empathy. The study suggests a biological basis for empathic connection during psychotherapy, with implications for improving therapeutic tec...
A genetic variant of BARD1 has been found to be associated with an increased risk of breast cancer, particularly in women who carry the BRCA2 mutation. The study suggests that inheriting this allele may increase a woman's breast cancer risk, but for most women, the risk is only slight.
Physiologist Dr. Pawelczyk highlights the human body's challenges in space life medicine and physiology, including radiation effects and heavy metal ion bombardment. He emphasizes the importance of current and future research to address these issues and prevent health problems such as osteoporosis and cancer risk.
The grant unifies labs, extending technologies and adding computation and visualization resources. Researchers will analyze large volumes of data from non-invasive imaging technologies to study brain function, detect cognitive impairment, and improve biometrics-based security.
A new study by Leah D. Whigham and colleagues found that the human adenovirus Ad-37 causes obesity in chickens, while other viruses like Ad-36 and Ad-5 have been linked to human obesity. More research is needed to determine if these viruses contribute to human obesity.
A new study examines the evolution of human life history, proposing a distinct phase known as 'late life,' where age-related deterioration ceases. This research suggests that late life may be characterized by a plateau in mortality rates after a certain age.
Researchers discover a novel proton-sensing G-protein coupled receptor that operates normally in acidic conditions, indicating potential new therapeutic avenues for arthritis, heart attacks, and strokes. The receptor's optimal function is at pH6.4, suggesting its role in synovial inflammation and cell proliferation.
The University of Oregon has developed a new environmental chamber to study the human body's response to everyday stresses. The chamber allows for precise simulation of extreme conditions, including altitude up to 18,000 feet and temperature control between 14 and 122 degrees Fahrenheit.
A study by Edward F. Coyle found that Lance Armstrong's long-term training increased muscular efficiency, leading to an 8% improvement in power production. Combining this with a planned weight loss, his steady-state power output improved by 18%. This increase in muscle efficiency may be due to an increase in type I muscle fibers.
The discovery suggests that strong selection for running fueled the growth of the human brain by relaxing constraints on protein and fat acquisition. Running has substantially shaped human evolution, with features like detached shoulders, springy tendons, and well-defined buttocks emerging to enable efficient long-distance running.
Researchers are creating a system that allows computers to monitor the health and emotional state of users, using thermal imaging to detect vital signs. The goal is to create a two-way exchange between humans and computers, enhancing the user experience while preventing illnesses.
This book presents six different models of the cardiovascular and pulmonary system, including a two-dimensional modeling of fluid dynamics in the heart. The models are introduced by case studies and can be studied individually, serving as an excellent introduction for researchers and graduate students.
Physiology aims to appeal to a broader audience with innovative features and artwork, showcasing the most up-to-date physiological research. The journal's design and editorial team are committed to making the content more accessible and readable.
The study, led by Shin'ya Nishida, utilized the multi-slit viewing illusion and found that pattern perception is more impaired by a mask or adaptation stimulus moving in the same direction as the pattern. Observers can see fine spatial components that are theoretically impossible to recover without motion information.
The study provides anatomical evidence of nanometer-sized particles in calcified human arterial and valvular tissue, which share characteristics with nanoparticles recovered from geological specimens. The cultured particles contain nucleic acids, suggesting ongoing synthesis and potential bacterial-like etiology of vascular calcification.