Articles tagged with In Vitro Fertilization
A study by Brigham and Women's Hospital researchers found no correlation between anxiety and depression in men on fertility treatment, nor was there a negative impact from antidepressant medication. Despite stress concerns, the study suggests men with anxiety should continue their treatment without fear of harming IVF outcomes.
The special issue explores achievements and challenges in reproductive endocrinology and infertility medicine, presenting strategies to bridge the gap between societal obligations and practice. Access to care remains a challenge for varying populations within societies and underserved regions.
Scientists analyzed nearly 1,000 IVF embryos to understand why some fail to develop, finding that genetic errors in cell division are more common than thought. The study reveals potential ways to improve IVF outcomes by changing the fertility treatment process and understanding the earliest stages of pregnancy.
A new AI tool can identify sperm in severely infertile men in seconds, compared to the hours it takes scientists. The algorithm improves antiquated approaches and increases the chance of a couple conceiving their own biological children while reducing stress on sperm and increasing efficiency.
Researchers developed a noninvasive diagnostic test to identify intact sperm in infertile men with nonobstructive azoospermia. The test uses protein biomarkers AKAP4 and ASPX to visualize well-developed sperm, potentially increasing success rates for surgical sperm extraction. This breakthrough may lead to new male birth control drugs ...
Researchers at São Paulo State University developed a new technique for analyzing male fertility potential using flow cytometry, which can detect and analyze chemical and physical characteristics of human sperm simultaneously. This technique has the potential to enhance the accuracy of fertility prediction and treatment.
A new IVF method using time-lapse monitoring has been found not to improve pregnancy rates or shorten the time it takes to get pregnant. The study, which evaluated 1731 patients over a year, also found that this approach does not lead to extra costs or benefits.
A new study led by OHSU researchers reveals that gene editing technology in human embryos can lead to unintended changes in the genome and may not accurately reflect gene edits. The study highlights the need for caution when using genetically edited embryos to establish pregnancies.
A survey found that a substantial portion of Americans are willing to use polygenic embryo screening and gene editing to increase the chances of having a baby admitted to a top-100 ranked college. The study suggests growing interest in using genetic technologies to influence offspring traits, including educational attainment.
Research from Texas A&M University reveals that male alcohol use has a significant negative influence on in vitro fertilization (IVF) success rates. The study highlights the importance of expanding fertility and prepregnancy messaging to emphasize the reproductive dangers of alcohol use by both parents.
A large-scale study found IVF-conceived children perform similarly to spontaneously conceived peers in terms of development and education. The research, involving over 400,000 Australian kids, suggests no significant differences in school outcomes between the two groups.
A new AI algorithm, STORK-A, can predict IVF embryo viability with 70% accuracy, reducing the need for invasive genetic testing. The algorithm analyzes microscope images of embryos and incorporates information about maternal age and IVF clinic scoring to detect aneuploidy.
Scientists have successfully created primordial germ cell-like cells (PGCLSs) from induced pluripotent stem cells of the northern white rhino Nabire, paving the way to produce artificial gametes. This breakthrough aims to prevent the extinction of the northern white rhinoceros and increase genetic diversity.
A University of Queensland-led research group has created the world's first successful donkey embryo using in-vitro fertilisation (IVF), which could save dozens of endangered donkey species. The team used a specialist IVF process known as intracytoplasmic sperm injection (ICSI) to create the viable embryo.
A new method of conventional IVF has been successfully developed by Katrin Hinrichs and colleagues, resulting in three healthy foals born to recipient mares. The technique offers a simplified alternative to existing methods like ICSI, which require expensive equipment and training.
Research found a 74% higher risk of hypertensive disorders in pregnancy among women who received frozen embryo transfers compared to those with fresh embryo transfers or natural conception. The study suggests that IVF treatment factors may be involved, but more research is needed to identify the specific risks.
Scientists developed a same-day test to identify abnormal fetal chromosomes using prenatal tests and tissue from miscarriage or biopsies. The STORK test shows promise in diagnosing genetic causes of miscarriage and streamlining IVF, potentially saving time and cost.
Researchers used multiple 'omics' techniques to evaluate spindle transfer, a new IVF option that avoids mitochondrial disease inheritance. The study found no significant differences in DNA copy number or RNA expression profiles between spindle transfer and control embryos.
Researchers at Columbia University Irving Medical Center discovered that most IVF embryo failures are due to spontaneous errors in DNA replication during cell division. These errors can cause chromosomal abnormalities, leading to the failure of embryos to develop, a common obstacle in fertility treatments.
A new study published in PLOS Biology found that IVF embryos often undergo genetic and metabolic changes that inhibit development. The researchers discovered that certain embryos enter a senescent-like state, but treating them with resveratrol can help overcome this arrest and promote further development.
A Rutgers study predicts a woman's risk of miscarriage based on her genome, providing valuable insights for reproductive choices and fertility treatment plans. The researchers developed an algorithm using machine learning methods to identify genetic variants associated with aneuploidy in human eggs.
A new micro-device has been developed to streamline the Intracytoplasmic Sperm Injection (ICSI) procedure, allowing more IVF clinics to offer this treatment. The device, smaller than a pinhead in size, holds up to 10 eggs and simplifies the injection process.
A study of 280 IVF patients found that COVID-19 vaccination has no effect on IVF cycle stimulation characteristics or clinical outcomes. The study, published in JAMA Network Open, suggests that vaccination is safe for patients undergoing IVF treatments.
Research found that IVF clinics offering money-back guarantees have a higher live-birth success rate and lower multiple birth risks compared to those without MBGs. The study suggests that these programs serve as signals of high-quality care in the field of IVF and other healthcare services.
Researchers have discovered molecules that could be candidates for contraceptives or fertility enhancers using human blastoid models. These models also show promise in improving the self-organization of stem cells during IVF procedures.
A study found that many IVF embryos with chromosomal abnormalities have the potential to lead to successful pregnancies. Embryos with low-grade mosaicism had similar live birth rates and miscarriage rates as euploid embryos.
Researchers at the University of Kent identified strong evidence-based benefits of preimplantation genetic testing for aneuploidy (PGT-A) in IVF. Live birth rates per embryo transferred and per treatment cycle were significantly higher with PGT-A compared to regular IVF, especially in women over 40.
A recent study suggests that infants conceived through in vitro fertilization (IVF) may be at a higher risk of developing craniosynostosis, a type of skull deformity. The four percent prevalence rate among IVF-conceived infants is considerably higher than the estimated one case per 1,800 to 2,200 births. Further studies are needed to c...
Researchers at RMIT University have discovered a Teflon-like molecule on the womb's surface that decreases at a certain point in the menstrual cycle, opening the 'golden window' for pregnancy success. This finding could lead to improved IVF success rates and potentially treat underlying causes of infertility.
A mathematical model developed by Rutgers University scientists can help explain why many pregnancies and IVF attempts fail. The study highlights the importance of understanding errors in female cell division, which increase with age and are linked to aneuploidy, a leading cause of early miscarriage and IVF failure.
A study of almost 276,000 children found a small association between IVF conception and an increased risk of childhood cancer, mostly rare tumor types. The link was limited to the first decade of life and was found in only a subset of cancers.
Women who undergo infertility treatment are more likely to experience severe pregnancy complications, such as postpartum hemorrhage and sepsis. Researchers found a 40% increased risk among women who received in vitro fertilization compared to those without treatment.
A randomized clinical trial of 824 women undergoing IVF found no significant difference in live birth rates between those receiving acupuncture and sham acupuncture. The study, published in JAMA, provides insight into the effectiveness of acupuncture in fertility treatments.
A study published in the New England Journal of Medicine found that women using IVF have similar chances of having a baby with fresh or frozen embryos. The research, involving 2,157 women, showed no significant difference in live birth rates between the two groups.
A new analysis of published studies found a 45% increased risk of congenital heart defects in IVF-conceived children compared to spontaneously conceived children. The study included 25,856 children from IVF and 287,995 from spontaneous conception, finding 1.30% and 0.68% cases of congenital heart defects respectively.
A new analysis found an approximate 80% increased risk of spontaneous preterm birth when women conceive through in vitro fertilization. This risk is significant enough to warrant ultrasound cervical screening to apply preventive strategies.
Researchers at Baylor College of Medicine discovered that follistatin promotes decidualization and supports embryo implantation. In a mouse model, female mice lacking follistatin produced fewer pups and failed to attach embryos to the uterine wall.
A recent study published in JAMA Network found that women with insurance coverage for IVF were more likely to attempt the procedure again and had a higher probability of live birth compared to those who self-paid. The research, conducted at Washington University in St. Louis, included 1,572 women and observed them through four cycles.
A $440,000 NIH grant is supporting a 3-year study examining the impact of cigarette smoke and genetic factors on female fertility. The researchers will assess ovarian reserve, in vitro fertilization success rates, and NAT2 genotype to better understand the relationship between smoking, genetics, and infertility.
A study of 1,508 infertile women with PCOS found that frozen embryo transfers had lower rates of ovarian hyperstimulation syndrome and pregnancy complications compared to fresh embryo transfers. Women with PCOS who received frozen embryos also had higher rates of live births and better birth weights.
A study of 19,158 women who underwent IVF treatment and 5,950 women starting other fertility treatments found no association between IVF and increased breast cancer risk. Women with 7 or more IVF cycles had a significantly decreased risk compared to those treated with 1-2 cycles.
A new study confirms BPA's detrimental impact on IVF success, with embryo death rates increasing linearly as BPA exposure grows. The findings support decades of research suggesting BPA's role in reproductive toxicity, emphasizing the need for regulation and control of this chemical.
A new microscopy method developed by Tel Aviv University researchers can identify strong sperm candidates without staining, improving the success rates of assisted reproductive technology treatments. The device uses phase imaging methods to assess sperm viability and is cost-effective enough to be used in any doctor's office.
The number of donor eggs used in IVF has increased significantly in the US, from 10,801 in 2000 to 18,306 in 2010. Good perinatal outcomes also improved, with a rise from 18.5% to 24.4%, while average donor age remained stable at 28 years and recipient age was not associated with outcomes.
A Swedish study of over 2.5 million children found a small, statistically significant increased risk of mental retardation after in vitro fertilization (IVF), but no association with autistic disorder. The study suggests that further research is needed to understand the long-term implications of IVF.
New research suggests that in vitro fertilization (IVF) is associated with a higher risk of birth defects, including those of the eye, heart, reproductive organs, and urinary systems. The study found that IVF infants were 1.25 times more likely to experience birth defects compared to naturally conceived infants.
A recent study by Hiroki Kurihara's team at the University of Tokyo discovered that Sirt3 helps safeguard mouse embryos against oxidative stress induced by in vitro fertilization and culture. The findings suggest that the negative effects of Sirt3 inactivation can be mitigated by using antioxidants or low-oxygen conditions during IVF.
Extending universal health coverage to IVF could decrease multiple births, their associated complications, and mortality rates. Quebec's legislation shows promise, with a decrease in multiple births after Finland's single-embryo transfer policy.
A Swedish study suggests that test-tube babies can be a profitable investment for states due to increased population and tax revenue. In the long term, the state benefits from subsidizing IVF treatment for involuntarily childless couples, which could potentially help boost population growth.
Scientists have identified a key molecular defect underlying sterility in some men with repeated failed ICSI procedures. The absence of the PLC zeta-1 protein in sperm prevents them from inducing egg activation and initiating embryo development.
Researchers at Mayo Clinic found that frozen sperm are just as effective as fresh sperm in in vitro fertilization. The cumulative live birth rate was higher for frozen sperm, with a success rate of 53.1 percent compared to 51.6 percent for fresh sperm.
A study in Egypt found cultural differences between Shi'ite and Sunni Muslims on IVF, with strict rules on third-party donation. Middle Eastern societies prioritize biological children due to prohibition of adoption and gamete donation.
A study of 199 women planning in vitro fertilization found that a 50% pregnancy rate was significantly higher for those who had people praying for them compared to the non-prayer group. The researchers acknowledge the results are incredible and hope to provoke discussion on potential biological or other factors at play.