Articles tagged with Carcinogens
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The WSU researcher will investigate genetic markers in UGT enzymes that indicate an increased risk of lung and head and neck cancers from tobacco smoke exposure. The study aims to develop personalized approaches to medicine and cancer treatment by understanding the detoxification pathway.
A recent meta-analysis found increased bladder cancer risk in certain occupations, with workers exposed to aromatic amines and polycystic aromatic hydrocarbons facing the highest risks. The study's findings suggest that efforts to reduce the impact of occupational bladder cancer should be targeted towards these high-risk occupations.
Research conducted by Lynda Dunn reveals that diathermy smoke contains nine hazardous compounds, four of which are carcinogenic, posing a risk to surgical personnel. The use of extraction devices is recommended to minimize exposure and improve workplace conditions.
Researchers have developed a method to track the movement of polycyclic aromatic hydrocarbons (PAHs) through the human body, shedding light on their role as carcinogens. The technology uses accelerator mass spectrometry to detect tiny amounts of PAHs in blood and explore how they are processed by humans.
The HHS has added four new substances to its 13th Report on Carcinogens, including ortho-toluidine, 1-bromopropane, cumene, and pentachlorophenol. Ortho-toluidine is a known human carcinogen, while the other three are reasonably anticipated to be human carcinogens based on studies in humans and animals.
A UCI-led study found high levels of carcinogens and other gases downwind of major refineries and chemical manufacturers in Alberta, Canada. The researchers detected elevated rates of cancers linked to these chemicals in nearby communities.
A Canadian case-control study found that women in jobs with high exposures to carcinogens and endocrine disrupters had an elevated breast cancer risk. The study highlights the importance of occupational studies in identifying environmental risk factors.
A new study found that compounds in the arcea nut can directly cause DNA damage and increase the risk of oral cancer in betel quid users. The substances, present in amounts sufficient to cause harm, were discovered through research published in Chemical Research in Toxicology.
Researchers have developed a method to apply beneficial mold K49 as a frontline defense against aflatoxin contamination in corn. By packaging K49 in bioplastic granules, the technology improves storage life and viability of the mold, reducing aflatoxin levels by 65-97%.
Scientists have identified (S)-NNN as a strong oral carcinogen in smokeless tobacco, found to induce large numbers of oral and esophageal tumors in laboratory rats. The US government is urged to regulate or ban the substance to protect the health of the 9 million US users of chewing tobacco and snuff products.
Researchers found that rats given daily multivitamin and mineral supplements showed an 84% reduction in pre-cancerous lesions and did not develop tumors when exposed to carcinogens. The study suggests that regular supplement use could help protect against colon cancer, giving cancer patients valuable guidance.
A recent study published in Food and Chemical Toxicology found that chlorophyll can protect against cancer when exposed to moderate levels of carcinogens, reducing liver and stomach tumors by 29-64% and 24-45%, respectively. However, high doses of chlorophyll increased tumor growth, questioning traditional lab research methods.
A recent study found that fetal exposure to carcinogens can lead to different types of cancer later in life, with the type of cancer depending on the stage of pregnancy when the fetus is exposed. The research also showed that mice who received multiple doses of a carcinogen had a higher rate of ovarian and lung cancer.
The National Toxicology Program has added eight substances to the HHS Report on Carcinogens, identifying chemicals that may increase cancer risk. These include formaldehyde, a known human carcinogen linked to nasal and other cancers, and captafol, a fungicide with limited evidence of lung cancer.
A new report from the American Cancer Society and other health groups identifies gaps in research for 20 suspected carcinogens, including lead, diesel exhaust, and styrene. The report aims to prioritize agents for further study and funding to address existing knowledge gaps.
A recent study found that chlorophyll and chlorophyllin can reverse the effects of aflatoxin poisoning by limiting its bioavailability. The research, led by DOE/Lawrence Livermore National Laboratory scientists, suggests that consuming greens may be a way to prevent long-term exposure to carcinogenic mycotoxins.
Researchers identify a potential molecular mechanism by which NNK promotes lung tumor formation and development through DNMT1 accumulation. Accumulation of DNMT1 in lung adenomas from NNK-treated mice and tumors from lung cancer patients correlated with poor prognosis, suggesting an important link between tobacco smoking and lung cancer.
A new study has found that chlorophyll and its derivative chlorophyllin are effective in limiting the absorption of aflatoxin in humans. The Phase 0 approach allows for the measurement of minute amounts of aflatoxin, revealing rapid absorption that is significantly limited after treatment with chlorophyll and chlorophyllin.
A new study from the University of Georgia suggests that outdoor smoking areas may be creating a new health hazard due to high levels of secondhand smoke. The research found cotinine levels up to 162% greater in non-smokers exposed to outdoor smoke, posing potential public health risks.
Burning paraffin wax candles can release known human carcinogens into the air, posing health risks. Replacing them with soy or beeswax candles may provide a healthier alternative.
Researchers at Oregon State University have completed the largest animal study in toxicology, challenging basic concepts of carcinogen risk assessment. The findings suggest that some chemicals may be safe at levels far higher than currently believed, and traditional methods need re-evaluation.
Asbestos export continues in Canada, violating its own limitations and the WHO's recommendation to end chrysotile mining. The practice contributes significantly to the global health crisis caused by asbestos-related diseases.
Dr. Jeanne Stellman urges government policy change to control carcinogenic chemicals in the workplace, citing years of wasted time examining the problem while few have championed efforts to regulate PCBs. Many hazardous chemicals remain unmonitored and unregulated, posing a significant threat to public health.
Researchers found that freeze-dried black raspberry powder restored activity to 460 genes in animals with esophageal cancer, many associated with cell proliferation and death. The study identified 53 genes important for early cancer development, which may be targeted by chemoprevention agents.
Research suggests that passive smoking poses a significant risk to lung cancer development, with sidestream smoke potentially more carcinogenic than mainstream smoke. The study proposes using DNA-lesion footprinting and mutagenicity analysis to identify unique biological markers for assessing lung cancer risk in relation to SHS exposure.
Researchers at NC State University have developed a method to silence a gene that turns nicotine into a carcinogen, resulting in a six-fold decrease in N-nitrosonornicotine and a 50% overall reduction in TSNAs. This breakthrough could lead to tobacco products with reduced amounts of cancer-causing agents.
A recent study found that restaurant workers exposed to tobacco smoke have higher levels of NNK, a potent lung carcinogen. The researchers concluded that clean air exemptions are unjustified and policymakers should prohibit smoking in all indoor workplaces.
A new study published in AJPH confirms legal liability to employers of workplace smoke. Nonsmoking employees who breathe in tobacco smoke from customers and co-workers are exposed to a potent carcinogen called NNK, which increases with the number of hours worked.
Research suggests that smokeless oral tobacco products and medicinal nicotine products may be safer alternatives to cigarette smoking. However, studies also found that these products may not be effective in reducing smoking use and related diseases. Medicinal nicotine products appear to be a better option for smokers looking to quit.
A study found that exposure to traffic emissions at menarche (first menstrual period) and first birth was associated with increased breast cancer risk in premenopausal and postmenopausal women, respectively. The findings support the hypothesis that early-life exposures contribute to breast cancer risk.
The report lists 58 substances as 'known human carcinogens' due to evidence from human studies, including HBV, HCV, and HPV. Eleven new substances have been added to the list of 'reasonably anticipated human carcinogens', including naphthalene, MeIQx, and lead.
A study found that users of reduced exposure tobacco products experienced decreased levels of nitrosamines in their urine after switching, with medicinal nicotine groups showing greater reductions. However, the actual reduction in carcinogen exposure for OMNI cigarette users was less than advertised.
Studies show that exposure to environmental carcinogens can cause DNA damage in the womb, increasing cancer risk. The fetus is more susceptible to genetic damage than the mother, highlighting the need for preventive policies.
Research found that pollution levels from vehicle traffic vary greatly depending on traffic volume and vehicle type, with larger vehicles emitting up to 60 times more carcinogens than smaller ones. The study suggests that diesel engines power these larger vehicles, exacerbating exposure in urban communities.
Researchers are working to isolate the nicotine N-demethylase gene, which converts nicotine into nornicotine, a potent carcinogen. The goal is to reduce levels of harmful nitrosamines in Burley tobacco and explore alternate uses for the crop.
Researchers have found that a specific carcinogen in cigarette smoke causes mutations in the K-RAS gene, leading to lung cancer. The study uses a mapping technique pioneered by Dr. Tang to pinpoint the exact site of damage, providing concrete proof that smoking is a cause of lung cancer.
Researchers at Stockholm University found high levels of acrylamide in fried, oven-baked, and deep-fried potato products. Cooking at higher temperatures increases acrylamide formation, while boiling is considered the safest method.
Researchers from Mayo Clinic and University of Minnesota found that tobacco industry sponsored research misled the public about the health risks of secondhand smoke. The study analyzed over 1.5 million pages of internal documents, revealing a campaign by the industry to deny health risks and preserve profits.
The National Toxicology Program (NTP) is hosting a public meeting to review its report on carcinogens and gather feedback from interested parties. Written and oral comments can be submitted until September 15, with the goal of informing the review process for the 10th edition of the Report on Carcinogens.