Articles tagged with Carcinogens
Recent research found that D-serine accelerates gastric cancer growth by suppressing cytotoxic T-cell activity and promoting immunosuppressive macrophages. High serum D-serine concentrations were linked to ICI therapy resistance in patients, suggesting its potential as a biomarker for disease progression.
Researchers detected chlorinated organophosphorus esters in solid waste, linked to toxic effects on the endocrine and reproductive systems. The substances, used as flame retardants, can cause cancer and harm human health if not managed properly.
Airborne levels of formaldehyde regularly exceed EU limits in 70% of NHS pathology departments, with poor monitoring and control contributing to the risk. The researchers call for national regulatory intervention to protect NHS employees' health, citing increased risks of respiratory and reproductive problems, as well as cancers.
A new study found that switching to a nicotine e-cigarette reduces toxicant exposure and improves quitting rates, with the nicotine group having a higher chance of quitting entirely. The study's results suggest that nicotine e-cigarettes could serve as an effective off-ramp for smokers seeking to reduce their tobacco use.
A study by Silent Spring Institute identified dozens of hazardous chemicals in hair extensions, including products made from human hair. The analysis revealed chemicals linked to cancer, hormone disruption, and developmental problems, prompting calls for stronger oversight and policy change.
A study published in Science of The Total Environment found that e-cigarette exposure alters gut microbiota composition and affects neurobehavior in zebrafish. The researchers observed disruptions in the gut microbiome, with reduced microbial network stability and altered community composition, suggesting potential health risks.
Researchers found that indoor tanning users in their 30s and 40s have more skin mutations than people twice their age, particularly in areas exposed to tanning beds. This can lead to an increased risk of skin cancer, including melanoma.
Researchers at the Federal University of São Carlos developed a sensor that can identify sodium nitrite in beverages. The device uses cork, laser-induced graphene, and electrochemical oxidation to detect the substance, which has potential carcinogenic effects. The sensor performed excellently with high sensitivity and good stability.
A study by SeoulTech researchers found high levels of polycyclic aromatic hydrocarbons (PAHs) in common food items, including cooking oils and meats. The QuEChERS-GC-MS method revealed carcinogenic compounds with limits of detection ranging from 0.006 to 0.035 µg/kg.
Researchers discovered a specific cell that responds to environmental toxins found in cigarettes, leading to aggressive tumor growth in mice with pancreatic cancer. The study also identified a type of immune cell that fuels this response while stopping the immune system from fighting tumor growth.
Research at University of Arizona Health Sciences found PFAS exposure affects gene activity, tied to cancers, neurological disorders, and autoimmune conditions. Changes in miRNA activity indicate potential health risks, suggesting a link between environmental exposures and disease.
A new study reveals that over half of Black and Latina women reported using personal care products with formaldehyde-releasing preservatives, highlighting critical safety gaps in product regulation. The study found that these chemicals are present in a wide range of products, including shampoo, lotions, and eyelash glue.
A new study links climate change to higher concentrations of inorganic arsenic in paddy rice, potentially raising lifetime health risks for populations in Asia by 2050. The research suggests a higher incidence of lung, bladder, and skin cancer, as well as cardiovascular disease and diabetes.
Researchers found significant cell changes in workers exposed to hexavalent chromium at levels below Sweden's current limit. The study suggests the need for stricter safety regulations and lower limits for this carcinogenic substance.
The Asia-Pacific region's H. pylori treatment practices show a growing consensus on primary and secondary prevention, but differences in antimicrobial resistance and medical resources persist. Establishing uniform standards for gastric cancer prevention will be crucial to addressing these disparities.
Researchers argue that the current paradigm of cancer as a genetic disease is unproductive due to inconsistencies in sequencing data. Alternative paradigms considering non-genetic processes, such as disruptions in gene regulatory networks and tissue organization, are proposed to guide future experiments.
Sylvester's Firefighter Cancer Initiative reduces cancer risk among firefighters and community members by addressing electric vehicle fires. A new gene-editing study aims to treat mitochondrial diseases, while a program connects patients with pathologists to improve understanding of complex results.
Researchers re-analyzed data for 111 products and found significant associations between production process, ingredient composition, and benzene levels. The study suggests opportunities to improve formulation, production, and distribution of benzoyl peroxide containing products to reduce the likelihood of them degrading into benzene.
A new study by Silent Spring Institute reveals how California's Proposition 65 law has driven companies to reformulate products, reducing the use of toxic chemicals and promoting safer consumer goods. The research found that companies prioritize eliminating Prop 65 chemicals altogether to avoid warnings and litigation.
Research led by a firefighter co-author sheds light on polycyclic aromatic hydrocarbons' affinity for DNA and ability to evade repair, highlighting potential health risks. The study's findings could inform public policy and accelerate the development of safer chemicals.
A new study found that benzoyl peroxide acne treatments lack stability and degrade into carcinogenic benzene when exposed to heat, UV light, or stored at room temperature. Refrigeration may be a practical solution to minimize unnecessary exposure until safer formulations are developed.
A new study reveals high levels of airborne plasticizers in Southern California, including phthalates known to cause reproductive harm and cancer. The study uses silicone wristbands to track exposure to these chemicals, finding that daily levels are both high and persistent.
Researchers have identified nearly 200 potential breast carcinogens in food contact materials, including plastics and paper, highlighting widespread exposure despite existing regulation. The findings emphasize the need for stronger preventative measures to reduce these chemicals in everyday products.
A new study reveals that at least 46,000 Australian welders are exposed to high levels of welding fume, a known carcinogen. The survey found that nearly 90% of workers were exposed to 'welding fume', with many working in confined spaces without proper ventilation.
A cross-sectional study found that e-cigarette users were less likely to undergo lung cancer screening. The research suggests that e-cigarettes contain carcinogens and may cause similar gene deregulations as combustible tobacco. This association may be particularly concerning for individuals who have quit smoking combustible cigarettes.
Researchers measured concerning levels of ethylene oxide in Louisiana's 'Cancer Alley' using mobile optical instruments. The study revealed that most locations had ethylene oxide levels above the EPA's acceptable upper limit, with some areas having potentially serious health risks for facility workers.
A new study found that cars release harmful flame retardants into the air, posing a significant public health risk. The researchers detected these chemicals in 101 cars, including suspected carcinogens like tris (1-chloro-isopropyl) phosphate, and linked warmer weather to higher concentrations.
Researchers from Osaka University found that exposure to environmental carcinogens and psychological distress decrease emotional wellbeing in Japanese people, with a 0.0064-year decrease for radon and 0.97 years for psychological distress. The study suggests that reducing exposure to these chemicals can help promote longer, happier lives.
Scientists have discovered a way to predict breast cancer risk based on specific chemical traits, identifying over 900 chemicals that could contribute to the disease. These chemicals are commonly found in consumer products, food, and workplaces, and can alter hormones or damage DNA.
A recent University of Cincinnati study found nicotine and a potent carcinogen called NNK on surfaces in children's homes, highlighting the persistence of thirdhand smoke pollutants even in homes with voluntary indoor smoking bans. The research emphasizes the importance of protecting children from tobacco exposure.
A study found polycyclic aromatic hydrocarbons (PAHs) in Southern Resident killer whales and Bigg's killer whales off the coast of B.C., with contaminants from oil spills and wildfire smoke. The presence of PAHs suggests recent exposures to toxic chemicals, emphasizing the need for improved pollution management.
Researchers from the University of California, Berkeley, and the University of Oxford found that formaldehyde inhibits DNA methylation, turning genes on or off. The study suggests that high levels of formaldehyde may suppress the body's attempts to prevent cancer.
Formaldehyde is a toxic chemical known to cause cancer but also plays an important role in human biology. New compounds developed by University of Leicester researchers allow for controlled release of formaldehyde in cells, enabling precise measurement of its effects.
A new study found that over 85% of Canadian products tested contained chlorinated paraffins, a known human carcinogen. The substances were detected in headphones, plastic toys, clothing, personal care products, and indoor paints.
Researchers at Washington State University found that CBD inhibits a key enzyme for nicotine metabolism, slowing down its effects and allowing smokers to wait before feeling the urge to smoke. The study suggests that CBD could be a useful tool in reducing harm from smoking and quitting nicotine addiction.
A new law restricts 1,4-dioxane levels in household cleaners and cosmetics, a potential human carcinogen common in everyday products. Experts recommend robust analytical methods for detection and quantification to meet regulatory requirements.
UCF researchers are developing a wearable, wireless health monitor to track physiological response to heat stress in firefighters. The device aims to identify correlations between heat stress and skin thermal activity for the first time, providing insight into the link between heat stress and serious medical issues.
A long-term International Space Station experiment measured the effect of space radiation on mouse embryonic stem cells, contributing to assessing safety and risks for human space flights. The study's findings show that actual biological effects of space radiation are in close agreement with earlier predictions.
A new study reveals that wood releases low levels of formaldehyde at room temperature due to a lignin-mediated Fenton reaction. Researchers have developed an effective, low-cost method to mitigate this release by mixing antioxidants and chelators with wood or spraying them on surfaces.
A study found that nearly 90% of areas studied had cancer-causing dioxins and PCBs in free-range eggs exceeding EU regulatory food limits. Eggs are a major pathway for human exposure to toxic chemicals, and contaminated sites include industrial waste incinerators and plastic burning sites.
Between 2017 and 2019, more than 1 million US youth aged 14 to 17 years became new daily tobacco users, with three-quarters of them vaping e-cigarettes daily. The majority of these young users were introduced to JUUL products, which had high nicotine concentrations and youth-appealing flavors.
A new study published in the Journal of the National Comprehensive Cancer Network (JNCCN) found that incorporating the Electronic Health Record-Enabled Evidence-Based Smoking Cessation Treatment (ELEVATE) program into electronic health records can significantly improve smoking cessation rates among cancer patients. The research demonst...
A new study from McGill University finds that people living near regions prone to wildfires may have a higher incidence of lung cancer and brain tumors. Exposure to carcinogenic wildfire pollutants on a chronic basis increases the risk of certain cancers, according to researchers.
A US study found that e-cigarettes were less popular as a smoking cessation aid in 2017 compared to FDA-approved pharmaceuticals. However, researchers did not see any reduction in relapse rates among those who quit using e-cigarettes.
A new study published in Environmental Research found that dust removal does not mitigate exposure to TDCIPP, a carcinogenic chemical commonly used in automobile seat foam. The researchers suggest that wearing a mask in the car may be an effective way to reduce exposure.
A recent UC San Diego study has found that e-cigarette use does not help smokers stay off cigarettes, but rather increases the risk of relapse. Former smokers who switched to e-cigarettes were more likely to relapse compared to those who remained tobacco-free.
A new study by PSE Healthy Energy reveals that over 16 billion barrels of oil and gas wastewater were disposed of in unlined pits, contaminating regional aquifers with salts and toxins. The Tulare Basin, home to four million people, is at risk due to a lack of regulatory protections for groundwater near these disposal sites.
Researchers from Massachusetts General Hospital have discovered a biological mechanism that transforms carcinogen-exposed cells into immunogenic cells, which can be harnessed therapeutically to fight treatment-resistant cancers. The mechanism involves the release of small proteins known as chemokines that recruit antitumor immune cells.
A new study by UC Riverside found that California's commuters inhale unacceptably high levels of carcinogenic chemicals like benzene and formaldehyde. Prolonged commutes over 20 minutes increase the risk of disease, including cancer and birth defects.
Scientists have identified key mechanisms within cells that disrupt breast cancer development when exposed to environmental chemicals. The study provides a roadmap for regulators to identify potential breast carcinogens and develop safer products.
Researchers found six substances with a strong link to bladder cancer in the urine of e-cigarette users, including carcinogens from combustion products and other tobacco products. The study's findings suggest that vaping may expose users to carcinogens similar to those found in cigarette smoke.
Scientists have developed a catalogue of DNA mutation 'fingerprints' caused by 41 environmental agents linked to cancer. The 'mutational signatures' can help doctors pinpoint the culprit responsible for a patient's tumour.
Researchers have created a genetically modified houseplant that can efficiently remove at least two toxins, formaldehyde and benzene, from the air. The plant's detoxifying potential was boosted by introducing a mammalian gene called CYP2E1 into its genome.
Scientists at UNIGE discovered that resveratrol, a molecule in grape skin and seeds, can prevent lung cancer in mice treated with a nasal formulation. The study showed a 45% decrease in tumor load and a higher concentration of resveratrol in the lungs after nasal administration.
A study published at the International Association for Dental Research found that e-cigarette users, especially those who also use combustible tobacco, are exposed to high levels of carcinogens similar to exclusive cigarette smokers. Non-cigarette tobacco product users are also at risk due to comparable exposure levels.
Researchers have identified dichloramine as the compound responsible for forming a potent carcinogen called N-nitrosodimethyalmine, or NDMA, in recycled water. The study found that minimizing dichloramine concentrations can reduce NDMA formation.
Researchers have developed a zeolite filter to reduce carcinogens in smoked foods, resulting in superior smoke flavor. The filtered smoke was found to contain up to 93% fewer carcinogenic compounds than unfiltered smoke.
A breakthrough discovery has been made by suppressing the aflatoxin-producing fungus in groundnut, significantly improving food safety. The research, published in Plant Biotechnology Journal, has potential to contribute to food security in under-developed countries.
Researchers measured firefighters' exposure to carcinogens and found post-fire levels of PAH metabolites in urine were 2.9-5.3 times higher than pre-fire levels. Skin decontamination may help reduce exposure, the study suggests.
A team of chemists developed a method to produce polycarbonates from limonene and CO2, replacing bisphenol-A (BPA) as a precursor. This bioplastic production approach reduces toxicity and offers a sustainable alternative for various industries.