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Science News for October 19, 2022


Two drugs reverse key pancreatic cancer step in the lab

Scientists at the University of Florida have identified two small molecules that inhibit precancerous cell progression and reverse a key process involved in pancreatic cancer progression. This discovery could lead to earlier treatments and improved survival rates for patients with pancreatic cancer.

SourceUniversity of Florida·JournalCell Death Discovery·TypeExperimental study·DateOct 19, 2022

DGIST research team led by Professor Sangaraju Shanmugam developed an eco-friendly ammonia catalyst

A new eco-friendly catalyst has been developed to convert nitric oxide into ammonia with high efficiency and stability. The core-shell nickel nanoparticle coated with nitrogen-doped carbon nanostructured electrocatalysts offers a Faradaic efficiency of 72.3% at low overpotential, making it suitable for large-scale industrial applications.

Engineers record neurons to pinpoint synaptic links

Researchers created a 3D electrode array that maps the locations and activity of up to 1 million potential synaptic links in living brains. The system uses recordings of millisecond-scale evolution of electrical pulses in tens of thousands of neurons, allowing for dense and accurate mapping of brain circuits.

SourceRice University·JournalNature Biomedical Engineering·TypeExperimental study·DateOct 19, 2022

New window into brain’s computational function

The study found that human neocortical pyramidal neurons have a more elaborate structure than other mammals, with larger and more complex dendritic trees. This enhancement may contribute to the brain's increased processing power. The research has implications for understanding how the brain is affected in diseases such as epilepsy.

SourceUniversity of Queensland·JournalCell Reports·TypeExperimental study·DateOct 19, 2022

A 10,000-year-old infant burial provides insights into the use of baby carriers and family heirlooms in prehistory

Researchers found evidence of a 10,000-year-old infant carrier at the Arma Veirana site in Liguria, Italy. The carrier was buried with the infant, nicknamed Neve, who wore over 70 pierced shell beads and pendants that were likely handed down as heirlooms.

SourceUniversity of Colorado Denver·JournalJournal of Archaeological Method and Theory·TypeObservational study·DateOct 19, 2022

Clear as mud

A team of researchers used clear mud to study turbulence in water flows, discovering that low clay concentrations alter the structure of turbulent dynamics. This finding has implications for understanding sediment transport and predicting flow behavior in natural environments.

Does topic consistency matter in movie reviews? A study of critic and user reviews and their impact on movie demand

Researchers found that content overlap between critic and user reviews increases movie demand, particularly for movies with mediocre review ratings. The study suggests that producers and marketers can leverage this by engaging with both professional critics and general consumers to find commonalities in their reviews.

SourceAmerican Marketing Association·JournalJournal of Marketing·DateOct 19, 2022

Trapping polaritons in an engineered quantum box

Australian researchers have engineered a quantum box for polaritons in a two-dimensional material, achieving large polariton densities and a partially 'coherent' quantum state. The novel technique allows researchers to access striking collective quantum phenomena and enable ultra-energy-efficient technologies.

SourceARC Centre of Excellence in Future Low-Energy Electronics Technologies·JournalPhysical Review Letters·TypeExperimental study·DateOct 19, 2022

Patients believe in psychotherapy more when practitioners demonstrate warmth and competence

Research found that therapists with high warmth and competence can shape patients' expectations by inspiring more positive beliefs about the effectiveness of therapy. This study suggests that practitioners' characteristics, such as warmth and competence, can influence clinical outcomes.

SourceAssociation for Psychological Science·JournalClinical Psychological Science·TypeExperimental study·DateOct 19, 2022

Researchers develop system to test brain ultrasound treatments in mice

A new system has been developed to deliver ultrasound stimulation to the brain in awake, naturally behaving mice, allowing researchers to evaluate its effects on sleep and working memory. This advance will help scientists test different ultrasound treatment protocols in mouse models of diverse neurological conditions.

SourceWiley·JournalAdvanced Science·DateOct 19, 2022

Shopping vouchers help women to stop smoking during pregnancy

A UK trial found that offering up to £400 in shopping vouchers to pregnant women can more than double the proportion who remain smoke-free by late pregnancy. However, most women relapsed after giving birth. The study suggests that financial incentives can be an effective tool to reduce smoking during pregnancy and improve health outcomes.

SourceBMJ Group·JournalThe BMJ·TypeRandomized controlled/clinical trial·DateOct 19, 2022

After more than 300 years of study, researchers developed a new way to understand bacteria

A Princeton team invented a way to observe bacteria in 3D environments, finding that colonies consistently form intricate, branching shapes resembling broccoli. They discovered two factors causing these shapes: nutrient and oxygen availability, and the colony's internal structure.

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 19, 2022

Durable, inexpensive catalyst reduces carbon footprint of ammonia production

Researchers develop stable catalyst that can produce ammonia at rates similar to conventional metal nitride catalysts, reducing the need for fossil fuels and lowering CO2 emissions. The new catalyst is chemically stable in the presence of moisture, enabling more efficient production under milder conditions.

SourceTokyo Institute of Technology·JournalAngewandte Chemie International Edition·TypeExperimental study·DateOct 19, 2022

Landscape of molecular contacts: How the coronavirus SARS-CoV-2 communicates with human cells

A team of scientists has identified over 200 direct protein-protein contacts between the SARS-CoV-2 virus and human cells, shedding light on the mechanisms underlying severe COVID-19. The study reveals chains of connections between viral proteins and infection-relevant human genes, with implications for disease severity and treatment.

UCLA engineers design AI material that learns behaviors and adapts to changing conditions

Researchers develop mechanical neural networks (MNNs) with tunable beams that can learn behaviors and adapt to external forces. The MNNs, composed of a triangular lattice pattern, exhibit smart properties through machine learning algorithms. Early prototypes overcame lag issues and achieved accurate performance in various applications.

SourceUniversity of California - Los Angeles·JournalScience Robotics·TypeExperimental study·DateOct 19, 2022

Switching tracks: Changing the trafficking of the glucagon receptor in the liver regulates its metabolic signaling

Helmholtz Munich researchers identified a novel strategy to alter glucagon receptor signaling by changing its intracellular localization. This approach offers therapeutic potential for treating type 2 diabetes by uncoupling glucose and lipid metabolism-related effects.

Ludwig Lausanne researchers develop strategy to noninvasively monitor key immune cells in tumors

The study, led by Johanna Joyce, develops a strategy to noninvasively monitor key immune cells known as macrophages within brain and breast tumors. The researchers use nanoparticles labeled with fluorine isotopes that emit distinctive signals detectable by MRI, allowing for the direct imaging of TAMs across tumor geography.

SourceLudwig Institute for Cancer Research·JournalScience Translational Medicine·DateOct 19, 2022

‘Farmer-researchers’ join front line in testing crops

A recent study from the Alliance of Bioversity International and CIAT shows that tricot, a citizen science approach for on-farm experimentation, generates agricultural data via local organizations in Central America. The approach enables farmers to contribute their time and land, reducing trial costs and increasing applicability.

Deeper understanding of the icy depths

Researchers at Hokkaido University have discovered the importance of Frazil ice in producing dense cold water, which is a key component of global ocean circulation. This finding has significant implications for understanding the impact of global warming on this process.

SourceHokkaido University·JournalScience Advances·TypeObservational study·DateOct 19, 2022

Study: Live chat boosts college women’s class participation

A recent UNLV-led study discovered that women enthusiastically embraced live chat during pandemic Zoom classes, with ratings showing significantly higher engagement than men. The researchers hope this data can help colleges incorporate technology into hybrid and in-person courses to increase underrepresented groups' access to STEM fields.

SourceUniversity of Nevada, Las Vegas·JournalPLOS ONE·TypeData/statistical analysis·DateOct 19, 2022

Yellow pigment keeps social amoebae together

Researchers at Leibniz-HKI discovered a yellow natural substance that regulates the multicellular stage of the amoeba <em>D. discoideum</em>. The polyketide, dictyoden, prevents premature hatching from spores, maintaining the development cycle. The study provides insights into the complex transition from single- to multicellularity.

SourceLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute -·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 19, 2022

Type 1 diabetes: New findings on the development of the autoimmune disease in children

A long-term study on infants and young children with increased genetic risk of type 1 diabetes found that metabolic changes occur much earlier than previously assumed. Blood sugar levels were found to be higher in children who developed autoimmunity, suggesting a potential indicator for islet cell dysfunction.

Chang'E-5 mission returned samples shed new light on our moon's surface makeup and geologic history

The Chang'E-5 mission returned samples that revealed a previously unknown iron-rich and high-calcium surface of basalts, challenging previous assumptions about the lunar geology community. The samples were primarily composed of pyroxene, contradicting earlier studies that indicated a high abundance of olivine.

SourceChinese Academy of Sciences Headquarters·JournalNature Communications·DateOct 19, 2022

Drones show potential to improve salmon nest counts

A Washington State University study showed that drone photography can effectively estimate the number of rocky hollows in the Wenatchee River where salmon create their eggs. The researchers found roughly double the number of redds using drones compared to ground-level observations, but with high variability. This technology has potenti...

SourceWashington State University·JournalRiver Research and Applications·DateOct 19, 2022

A drop in the sea of electrons

Scientists at Swinburne University of Technology and FLEET collaborators observe and explain signatures of Fermi polaron interactions in atomically-thin WS2 using ultrafast spectroscopy. Repulsive forces arise from phase-space filling, while attractive forces lead to cooperatively bound exciton-exciton-electron states.

SourceARC Centre of Excellence in Future Low-Energy Electronics Technologies·JournalNature Communications·TypeExperimental study·DateOct 19, 2022

Novel PET imaging agent detects earliest signs of Alzheimer’s disease

A new radiotracer, 18F-SMBT-1, detects overexpressed monoamine oxidase-B in cognitively unimpaired individuals with high beta amyloid levels, a key early sign of Alzheimer's disease. The agent shows increased binding to reactive astrocytes, suggesting its potential as a surrogate marker for detecting Alzheimer's disease.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateOct 19, 2022

Ecological imbalance: How plant diversity in Germany has changed in the past century

A study by Martin-Luther-Universität Halle-Wittenberg and the German Centre for Integrative Biodiversity Research found that 41% more plant species in Germany have decreased in abundance over the past 100 years, while only 19% have increased. This uneven distribution of gains and losses indicates a significant loss of biodiversity.

SourceMartin-Luther-Universität Halle-Wittenberg·JournalNature·TypeMeta-analysis·DateOct 19, 2022

AGS releases framework for understanding the intersection of structural racism and ageism in healthcare

The American Geriatrics Society has released a framework for understanding the intersection of structural racism and ageism in healthcare. The framework highlights three fundamental changes: reflecting the population served, changing training and support for health professionals, and examining healthcare from an intersectional perspect...

SourceAmerican Geriatrics Society·JournalJournal of the American Geriatrics Society·DateOct 19, 2022

Acidic layer in single-walled carbon nanotubes facilitates confinement of anion impurities

Researchers at Okayama University found that an acidic adsorption layer in carbon nanotubes facilitates efficient adsorption of negatively charged nitrate anions, making the aqueous solution alkaline. This study provides a novel model for designing carbon nanotubes suitable for ion adsorption and purification.

SourceOkayama University·JournalJournal of Colloid and Interface Science·TypeExperimental study·DateOct 19, 2022

Development of new technology for wastewater treatment for semiconductor production

A new photocatalysis-based technology has been developed to completely decompose low concentrations of alcohol in semiconductor wastewater. This breakthrough could significantly reduce the cost and water resources required for wastewater treatment, making it a more sustainable solution for the industry.

SourceNational Research Council of Science & Technology·JournalChemical Engineering Journal·DateOct 19, 2022

OCD on TV

A new study published in GigaScience has made available an enormous amount of behavioral data from an animal model of obsessive-compulsive disorder (OCD), comprising over 2 years of continuous recording. The data set, which is the culmination of a 15-year study, provides insights into the mechanisms of OCD and potential treatments.

SourceGigaScience·JournalGigaScience·TypeData/statistical analysis·DateOct 19, 2022

A difficult key factor

Researchers used excess mortality data to calculate a significantly lower R0 value of 1.34 for SARS-CoV-2 infections in March 2020, contrary to earlier estimates which ranged from 1.95 to 6.49.

SourceUniversity of Würzburg·JournalNature Communications·TypeData/statistical analysis·DateOct 19, 2022

Climate change could make High Arctic fertile ground for emerging pandemics: uOttawa study

A novel genetic analysis by University of Ottawa researchers reveals that climate change could lead to an increased risk of viral spillover in the High Arctic. This increased risk may result in new viruses infecting previously uninfected hosts, potentially leading to emerging pandemics.

SourceUniversity of Ottawa·JournalProceedings of the Royal Society B Biological Sciences·TypeComputational simulation/modeling·DateOct 19, 2022

UCLA researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme

Researchers at UCLA Jonsson Comprehensive Cancer Center and Semel Institute identified the gene P300 as a potential therapeutic target for treatment-resistant brain cancer glioblastoma multiforme. By blocking P300, tumor cells can be prevented from recovering and growing under the hostile conditions created by radiation therapy.

SourceUniversity of California - Los Angeles Health Sciences·JournalNature Communications·TypeExperimental study·DateOct 19, 2022

In medieval Norway, high-class people had stronger bones

A study published in PLOS ONE found that high-status individuals in medieval Norway had higher bone mineral density and were taller than those from lower socio-economic backgrounds. This suggests that socioeconomic status may have played a role in shaping health outcomes over time.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateOct 19, 2022

NIH-supported study finds racial disparities in advanced heart failure treatment

A recent NIH-supported study found that Black adults treated at advanced heart failure centers received potentially life-changing therapies, such as transplants and heart pumps, about half as often as white adults due to racial bias. The researchers also suggest that unconscious bias and overt racism may be driving these disparities.

SourceNIH/National Heart, Lung and Blood Institute·JournalCirculation Heart Failure·DateOct 19, 2022

A smoky solution — for plants

Researchers have made a surprising discovery that liquid smoke can enhance plant defense against pests and diseases, leading to new farming practices. The study found that sunflowers grown in soil treated with liquid smoke had larger, thicker, and greener leaves and appeared less prone to pests and disease.

SourceUniversity of Missouri-Columbia·JournalInternational Journal of Molecular Sciences·DateOct 19, 2022

How groups best work together

Researchers Dr. Fabian Pels and Prof. Jens Kleinert developed an integrative group flow theory that explains the conditions for optimal group performance. The IGFT highlights the importance of interpersonal coordination, positive relationship quality, and continuous maintenance of primary and secondary fits to achieve group flow.

SourceGerman Sport University·JournalGroup Dynamics Theory Research and Practice·TypeSystematic review·DateOct 19, 2022

Study: new model for the transmission of cultural knowledge

A new study by Helena Miton and Simon DeDeo presents a model for the transmission of tacit knowledge, which is passed down with limited specification. The model captures how learners overcome constraints to succeed in complex practices, predicting stability over time with minimal information.

SourceSanta Fe Institute·JournalJournal of The Royal Society Interface·TypeComputational simulation/modeling·DateOct 19, 2022

Changing the face of innovation

A new MUSC initiative aims to increase the number of women entrepreneurs by offering coaching, mentoring, and training opportunities. The program will pair trainees with successful biomedical entrepreneurs, providing valuable role models and guidance. By addressing gender inequity in STEM fields, STEM-CREW seeks to advance the careers ...

Do caffeine and alcohol affect fertility treatments?

A recent study found no association between women's caffeine consumption and pregnancy or live birth rate after fertility treatments. However, moderate alcohol consumption (84g/week) was associated with decreased pregnancy and live birth rates in both men and women undergoing IVF/ICSI treatment.

SourceWiley·JournalActa Obstetricia Et Gynecologica Scandinavica·DateOct 19, 2022

Discovery of 119-million-year-old selfish genes in yeast potentially alters our understanding of how parasitic DNA impacts genome evolution

Researchers have discovered a family of selfish genes, wtf, that have survived for over 100 million years in yeast, contradicting established beliefs on their longevity. These 'killer meiotic drivers' transmit themselves to half of offspring and destroy reproductive cells without being suppressed by natural selection.

SourceStowers Institute for Medical Research·JournaleLife·TypeObservational study·DateOct 19, 2022

Method for decoding asteroid interiors could help aim asteroid-deflecting missions

Researchers have developed a method to map an asteroid's interior structure based on its spin changes during close encounters with Earth. This technique, called AIME, could help scientists plan more effective defense strategies for asteroids like Apophis, which poses a significant hazard if it were to make impact.

SourceMassachusetts Institute of Technology·JournalMonthly Notices of the Royal Astronomical Society·DateOct 19, 2022

To be less sedentary, you may need a more active friend

A mathematical model suggests that social interactions between sedentary and moderately active people can stimulate higher levels of overall physical activity in a population. The model found that interacting with moderately active individuals helped sedentary populations become more physically active over time.

SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateOct 19, 2022