A team of researchers from Martin-Luther-University Halle-Wittenberg has discovered a transport pathway for manganese in plants and the role that BICAT3 plays in this process. The protein is responsible for transporting manganese to where it needs to go in plant cells, leading to improved crop growth.
A novel HNF1A gene variant has been found to cause monogenic diabetes, affecting almost seven percent of all cases in Greenland. This discovery may pave the way for precision treatment using tablet therapy with sulphonylurea, offering a simpler and cheaper alternative to insulin.
A study in Japan reveals that universal screening methods for biliary atresia, a rare and severe lung condition in infants, are cost-effective. The research found that stool color card screening and direct bilirubin testing gained significant clinical benefits and saved lives.
A survey of over 1,000 cancer patients and 150 oncologists found that nearly two-thirds of patients want to know about complementary therapies before starting conventional treatment. Integrative oncology can help manage side effects and improve overall well-being, with 50% of patients and 60% of oncologists strongly agreeing.
The DGIST research team successfully developed a rotation-based triboelectric neuro-stimulator capable of real-time modulation of stimulus parameters. This innovation overcomes the limitations of existing neurostimulators by enabling controlled frequency, pulse width, and amplitude adjustments during rotation.
Global immunization efforts have made polio a rare disease, but healthcare workers still need to be vigilant for acute flaccid paralysis. Dr. Marina Salvadori emphasizes the importance of alerting healthcare workers to this diagnosis as elimination is within reach.
Researchers at University of Michigan discovered how cerium flow batteries lose voltage due to complex molecular interactions. This understanding will help design more efficient cerium-based batteries with reduced voltage loss.
A new study found that small molecules in breast milk, specifically miR-375, can reduce the likelihood of infants developing allergic conditions like atopic dermatitis and food allergies. Infants who consumed more miR-375 had lower rates of these conditions, suggesting a potential protective effect of breast milk against allergies.
Researchers have discovered that leprosy parasites can reprogram liver cells to increase organ size without scarring or tumors. This natural process may be adapted to renew ageing livers and improve healthspan in humans.
A team at the University of Manchester has received funding to develop a novel hydrogen separation technique, which could make clean energy production cheaper and more sustainable. The project aims to overcome cost barriers for commercial hydrogen extraction from unrecyclable wastes, supporting ambitious clean energy targets.
A recent study by Washington State University found that rural public schools are less likely to provide mental health services compared to urban schools, with only 38.3% offering treatment. Rural schools also reported lower funding and lack of access to qualified professionals as barriers to providing these services.
Researchers at the University of Oldenburg have developed a new statistical model that accurately describes wind turbulence and generates fully three-dimensional wind fields using limited measurement points. This breakthrough enables precise wind turbine load estimation and improves wind farm planning, with applications in various fiel...
Researchers discover individual gold atoms can target specific C-H bonds in organic molecules, enabling a low-energy reaction at room temperature. This breakthrough addresses two significant challenges and paves the way for the synthesis of novel organic and metal-organic nanomaterials.
The proposal aims to provide a central repository for battery test information, enabling researchers to use advanced data science methods to accelerate battery technology development. The availability of open-source information on batteries is limited, but the Battery Data Genome could help address this challenge.
A study found widespread occurrence of microplastics in Monterey Bay water and in the digestive tracts of anchovies and common murres. The researchers discovered that almost a quarter of the examined murres had particles exhibiting estrogenic activity, potentially disrupting hormone functions.
Researchers at Saitama University reveal how and why the sensitive plant Mimosa pudica moves its leaves rapidly through calcium-mediated signaling molecules. The study found that bursts of fluorescence travel rapidly throughout the leaves, triggering leaf movements.
Researchers at Lehigh University have secured $13.2 million in funding to improve hydrogen generation and carbon capture/sequestration technologies through a partnership with Georgia Tech's UNCAGE-ME Center. The goal is to develop catalysts that can mitigate the degradation of these technologies in real-world conditions.
A new study found that exposure to outdoor artificial light at night is associated with impaired blood glucose control and an increased risk of diabetes. Chronic exposure to residential outdoor LAN was positively associated with blood glucose levels, insulin resistance and diabetes prevalence.
A three-year research project led by Aston University aims to prevent epileptic seizures in children. The team will explore how epilepsy becomes established in the brain and test new drugs using living tissue samples.
Opaganib, an oral small molecule pill, shows potential as a nuclear radiation injury therapeutic for homeland security medical countermeasures and antitumor radiotherapy. The compound protects normal tissue from radiation damage and improves antitumor activity and response to chemoradiation.
A study published in Nature Microbiology reveals that a protein complex called SMC5/6 initiates a process that silences HIV DNA proviruses, leading to latent infections. The researchers propose a molecule that inhibits this action as a potential therapeutic strategy to reactivate latent HIV-1 and help clear the body of infectious virus.
Researchers found that patients with more genetic material on chromosome 9 in their cancer cells survive longer after receiving immunotherapy. The discovery suggests a genetically defined axis that determines which HNSC patients will respond well or poorly to checkpoint inhibitors.
A research team developed a vaccine targeting synthetic opioid fentanyl to block its entry into the brain, preventing fatal effects. The breakthrough could have major implications for treating Opioid Use Disorder, with potential relapse prevention capabilities.
A team of researchers solved a century-long debate on why early land plants developed complex vascular systems, which enabled them to survive in drier environments. By analyzing fossil specimens and living plants, the team discovered that small changes in the vascular system led to improvements in drought tolerance.
A new study found that ER visits involving suicidal ideation among youth aged 5-19 increased by 59% from 2016-2017 to 2019-2021. The study also revealed a correlation between severe mental illness, substance use, and hospitalizations during the same period.
Researchers created an information engine using a glass bead suspended in water, exploiting thermal noise to convert it into work. The system uses Bayesian estimates to filter out measurement errors and performs significantly better than typical engines when noise is high.
A team of researchers used AI pattern recognition to re-analyze footprints from the Dinosaur Stampede National Monument and concluded that they were made by an ornithopod dinosaur, a herbivorous species. The results contradicted the long-held assumption of a vicious dinosaur predator.
Researchers developed an AI tool that analyzes plaque features on coronary CT scans to predict reduced blood flow, potentially reducing invasive tests. The tool could help doctors determine the next step in treatment plans and risk-stratify patients correctly.
The Vilcek-Gold Award honors immigrant healthcare professionals in the US who demonstrate an outstanding commitment to humanistic and community-centered care. The award includes a $10,000 cash prize, commemorative trophy, and presentation at the Association of American Medical Colleges' annual meeting.
The study reveals two neuron subgroups in NAc: NAc BLA and NAc PVT. These neurons regulate reward-seeking behavior and aversion, respectively. The findings provide insight into the brain's reward and aversion processing.
A new study finds that working-age people who survive serious traumatic injuries face a lasting financial burden, with higher rates of medical debt in collections and bankruptcy. The study suggests that restructuring health insurance plans to reduce or cap cost-sharing for highly necessary trauma care could help alleviate this issue.
Researchers at University of Würzburg discovered a novel phosphatase inhibitor that selectively blocks the proliferation of tumor cells. This breakthrough targets increased energy demands in diseases like cancer and autoimmune disorders, offering potential new therapies for treatment.
Researchers analyzed NGC 7469 with the JWST's mid-infrared detection instruments, revealing detailed dynamics of an active galactic nucleus and its impact on surrounding star-forming regions. The study sheds light on the effects of supermassive black hole winds on galaxy evolution.
A study found that ER visits for suicidal thoughts among youth aged 5-19 increased by 59% from 2016-2017 to 2019-2021, with hospitalizations rising by 57%. The research highlights the need for improved mental wellness support and training for healthcare providers.
Neutrophils can generate LTB4 through cooperative transcellular biosynthesis, rescuing defective swarming behavior in genetically deficient cells. This breakthrough enables therapeutic control of infection response and potentially auto-inflammatory processes.
A study found a possible link between COVID-19 mRNA vaccine-induced fever and antibody levels in younger, allergy-prone individuals. After the third dose, those with fever had higher antibody counts at 1 week post-vaccination, but not 1 month later.
Researchers found that a new drug inhibiting GRP78 effectively reduces SARS-CoV-2 replication in human lung cells. The drug also shows potential in treating certain types of cancer by suppressing mutant KRAS proteins.
Researchers have developed a new technology that can swiftly put brakes on an overheated Li-ion battery, shutting it down and preventing fires. The material, which uses thermally-responsive shape memory polymer, maintains high conductivity at normal temperatures.
A distinct population of oceanic manta rays was identified off the coast of Ecuador, with an estimated total population of over 22,000 individuals, making it more than 10 times larger than any other known subpopulation. The population is large and potentially healthy due to favorable conditions in the region.
Researchers developed a technique to measure long-term effects of antibiotic combinations, finding some combinations may reduce treatment effectiveness. Specific combinations were found to prevent resistance development and protect patients from aggressive bacteria.
A University of Oklahoma study aims to develop practical approaches to pinpoint hidden wireless devices, using a single smartphone and no professional equipment. The project focuses on safeguarding user privacy against unauthorized video or voice recordings from IoT devices.
Researchers have discovered a high-antioxidant ingredient in passion fruit peels that can preserve fresh fruits and cuts in an edible coating, reducing spoilage and plastic packaging. The microencapsulated powders are stable, non-hygroscopic, and suitable for industrial applications.
A new statistical method called CLIMB provides a more efficient way to analyze genomic data across multiple conditions. The method combines principles from two traditional techniques, reducing computational intensity and producing biologically interpretable results.
A new study from researchers at Tufts University's Friedman School of Nutrition Science and Policy found that coalitions working to combat childhood obesity are more effective when members form close relationships with people in different organizations, learn new information rapidly, and share that knowledge with others. This can lead ...
Scientists at Northwestern Medicine have discovered a causal link between environmental phthalates and increased uterine fibroid growth. Exposure to certain phthalates, such as DEHP, may activate a hormonal pathway that causes fibroid tumors to grow. This study explains the mechanisms behind this association.
A study in over 85,000 individuals found that morning physical activity is associated with the lowest risk of heart disease and stroke. The findings were consistent regardless of daily activity level or individual's chronotype.
Researchers found that deleting a copy of the Arid1b gene in specific brain cells decreased inhibitory signaling, leading to changes in synaptic properties and connectivity. The study suggests that this gene may be a key target for therapeutics in treating autism spectrum disorder.
Researchers at City University of Hong Kong found that tailoring cobalt concentration in high entropy alloys prevents nanoparticles from coarsening at high temperatures. This strategy opens a pathway for designing novel thermally stable chemically complex alloys for various engineering fields.
Researchers developed a simple urine test to measure cystic fibrosis severity and assess treatment effects. The test reveals the extent to which new treatments are beneficial, correlating with disease severity and lung function.
A team from California Institute of Technology has developed a brain-machine interface device that can predict internal speech in patients with tetraplegia. The device, trained on single neurons in the supramarginal gyrus, achieved accuracy up to 91% in predicting eight words.
A randomized controlled trial found that both total ankle replacement and ankle fusion improve quality of life and have similar clinical scores in patients with end-stage ankle osteoarthritis. However, TAR is associated with greater wound-healing complications and nerve injuries, while AF is linked to more blood clots and nonunion of t...
A new study finds that seafood farming's growth rate has already peaked in 1996 and is now declining, requiring rebuilding of wild fish stocks to meet future demand. Without this approach, relying solely on aquaculture could lead to a global seafood shortage by 2030.
A new study by UNSW and the University of Melbourne found that estimates of Probable Maximum Precipitation (PMP) for large dams in Australia are expected to increase by 14-38% on average over the next 80 years. This is due to climate change and outdated modelling, which has not been updated since at least 20 years ago.
A new study in mice suggests that a short-term high-fat diet can induce hyperalgesic priming and allodynia, even in the absence of injury or preexisting conditions like obesity or diabetes. Researchers found that palmitic acid, a type of saturated fatty acid, binds to nerve cells, causing inflammation and mimicking injury to neurons.
Researchers at Utah State University found that the formation of K'gari Sand Island and the Great Barrier Reef were linked to major climate feedback changes during the Middle Pleistocene Transition. The team's study suggests that sea-level rise may have initiated the landforms' beginnings around 800,000 years ago.
Researchers at Nagoya University have developed a new method to control mosquito populations by altering the frequency of sound that males listen for. By using serotonin-inhibiting compounds, they reduced the range of frequencies males respond to and their response itself.
A new study has shown that total ankle replacement and ankle fusion surgeries equally improve quality of life for patients with advanced ankle osteoarthritis. However, a fixed bearing joint replacement showed significant improvement over ankle fusion in clinical scores.
A study from University of Cambridge found that young people who feel poorer than their friends have lower self-esteem and are more likely to be bullied. Feeling economically equal among peers had the best outcomes for mental health and social behavior.
A new study documents past changes in Earth's climate system by analyzing dust composition in samples collected from different areas and depths of the same glacier. The findings suggest that a complete dust record could offer more secrets than scientists realize, hinting at potential long-term perspectives on the Central Asian dust cycle.
This survey reviews vehicular mobility models, categorizing them into distribution, traffic, and driving behavior models. The models are applied to various scenarios in Intelligent Transport Systems (ITS), assessing their practicality and potential performance.