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Australian GenesisCare doctors co-author world-first international consensus statement on Cardio-Oncology

The international consensus statement provides critical recommendations for the cardiovascular management and follow-up of patients undergoing radiation therapy. The paper highlights the need to identify and address cardiovascular risk factors to prevent cardiotoxicity, emphasizing the importance of regular screening and treatment for ...

SourceGenesisCare·JournalJournal of the American College of Cardiology·TypeLiterature review·DateDec 13, 2021

American College of Cardiology, American Heart Association issue coronary artery revascularization guideline

The new guideline recommends a patient-centric approach to managing patients with coronary artery disease, incorporating clinical indications and multidisciplinary team decision-making. The guideline aims to improve quality of care and reduce disparities in treatment, particularly among women and underrepresented racial or ethnic groups.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateDec 9, 2021

1 in 10 cardiology trainee doctors in UK say they have been bullied

A survey of UK cardiology trainees reveals that bullying is a pervasive problem, with 1 in 10 reporting being subjected to abusive behavior. Women and those who qualified outside the UK are disproportionately affected, highlighting a need for targeted measures to address workplace bullying in medicine.

SourceBMJ Group·JournalHeart·TypeObservational study·DateDec 6, 2021

The diabetes medication that could revolutionise heart failure treatment

A new meta-analysis published in the European Journal of Preventive Cardiology suggests that Sodium-glucose co-transporter-2 (SGLT2) inhibitors can improve outcomes for heart failure patients with preserved ejection fraction. The medication has been shown to reduce the risk of death from heart-related causes and hospitalization by 22%.

SourceUniversity of East Anglia·JournalEuropean Journal of Preventive Cardiology·TypeMeta-analysis·DateNov 30, 2021

Mount Sinai cardiologist develops new risk score to help predict possible contrast-associated kidney injury after percutaneous coronary intervention

A new risk score developed by Mount Sinai researchers can help predict possible contrast-associated acute kidney injury among patients undergoing PCI. The 'Mehran-2 CA-AKI Risk Score' enhances management of high-risk patients before, during, and after the procedure.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalThe Lancet·TypeObservational study·DateNov 15, 2021

Researchers find benefits and drawbacks to two-step surgical approach for “leaky heart valves”

A NIH-funded study found that patients with a two-step surgical approach for 'leaky heart valves' had better short-term outcomes, but were more likely to need a pacemaker. The procedure involved repairing the tricuspid valve at the time of mitral valve surgery, and results showed reduced risk of death, reoperation, or severe regurgitat...

SourceNIH/National Heart, Lung and Blood Institute·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateNov 13, 2021

Study: Recommended approach for preventing blood clots after stent placement may not be as beneficial as once thought

A new study suggests that the recommended approach for preventing blood clots after stent placement may not be as beneficial as previously thought. The researchers found that the risks of dual antiplatelet therapy (DAPT) may now outweigh its benefits for most patients, due to improvements in stent technology and changes in patient demo...

SourceBeth Israel Deaconess Medical Center·JournalCirculation·DateNov 10, 2021

Study finds that PCI guided by FFR did not meet noninferiority for one-year outcomes compared to bypass surgery

A new study published in The New England Journal of Medicine found that percutaneous coronary intervention (PCI) guided by fractional flow reserve (FFR) did not meet noninferiority for one-year outcomes compared to bypass surgery. However, FFR-guided PCI performed favorably in patients with low SYNTAX scores and less complex disease.

SourceCardiovascular Research Foundation·JournalNew England Journal of Medicine·DateNov 8, 2021

Calculating a dangerous heartbeat

A team of researchers from Flinders University has developed a single mathematical equation that can accurately model and predict the behavior of ventricular fibrillation, a life-threatening heart rhythm. The equation uses principles from renewal theory to predict the population dynamics of 'rotors' found in the heart during VF.

SourceFlinders University·JournalHeart Rhythm·TypeObservational study·DateNov 7, 2021

UCSF-led study confirms some cancer immunotherapies may lead to myocarditis and other potentially serious arrhythmias

A new clinical syndrome of ICI-myocarditis has been identified, characterized by highly arrhythmogenic features. The study establishes specific electrocardiographic features to diagnose and prognosticate the syndrome, highlighting the need for further research on prediction and monitoring strategies.

SourceUniversity of California San Francisco Medical Center·JournalCirculation·TypeMeta-analysis·DateNov 5, 2021

Lifetime excess weight linked to subclinical heart injury

A study of 9,739 adults found that those with stable overweight and obesity had elevated cardiac troponin I levels, a marker of subclinical heart injury. Long-standing obesity is associated with injurious effects on cardiac health before symptoms occur.

SourceWiley·JournalJournal of Internal Medicine·DateOct 20, 2021

Scientists show how AI may spot unseen signs of heart failure

A new AI-based computer algorithm created by Mount Sinai researchers can identify subtle changes in electrocardiograms to predict heart failure. The algorithm was 94% accurate at predicting healthy ejection fractions and 87% accurate at detecting weakened hearts, offering a promising alternative to traditional diagnosis methods.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJACC Cardiovascular Imaging·TypeComputational simulation/modeling·DateOct 18, 2021

Flu and heart disease: The surprising connection that should convince you to schedule your shot

A recent review published in the Journal of the American Heart Association found that flu vaccination can significantly reduce the risk of heart attack and stroke in individuals with heart disease. Despite higher mortality rates from influenza, many Americans under 65 with heart disease have low vaccination rates.

SourceHouston Methodist·JournalJournal of the American Heart Association·TypeSystematic review·DateOct 15, 2021

Estimated pulse wave velocity predicts severe Covid

Researchers have discovered that estimated pulse wave velocity is an effective tool to refine risk stratification of hospitalized patients with Covid-19. The study found that the addition of ePWV to clinical predictive markers improved prognostic value for in-hospital mortality.

SourceNewcastle University·JournalScientific Reports·TypeRandomized controlled/clinical trial·DateOct 13, 2021

New research from Children’s Hospital Colorado shows dual therapy upon diagnosis of MIS-C improves cardiac outcomes

A recent study found that pediatric patients with Multisystem Inflammatory Syndrome (MIS-C) who received initial IVIG plus Infliximab had improved cardiac outcomes, reduced need for additional therapies, and faster resolution of inflammation. The updated care pathway recommends this intensified therapy for all MIS-C patients.

SourceChildren's Hospital Colorado·JournalPEDIATRICS·TypeObservational study·DateSep 30, 2021

Decision Science Digest: Highlights of peer-reviewed research published in INFORMS journals

Recent INFORMS journal research highlights the use of predictive modeling to forecast wildfire risks and optimize firefighting equipment placement. Additionally, studies investigate strategies to reduce cardiac stenting overuse and improve electric mobility service costs through optimized fleet rebalancing.

SourceInstitute for Operations Research and the Management Sciences·JournalINFORMS Journal on Applied Analytics·DateSep 28, 2021

Shrinking waveforms on electrocardiograms predict worsening health and death of hospitalized COVID-19 and influenza patients

Researchers found that shrinking waveforms on electrocardiograms can help identify high-risk patients with COVID-19 or influenza, allowing for more aggressive monitoring and treatment. The study also showed that this technique may be particularly useful in overwhelmed systems where timely intervention is crucial.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalThe American Journal of Cardiology·TypeData/statistical analysis·DateSep 24, 2021

Texas Heart Institute, University of Texas Medical Branch (UTMB) and 7 Hills Pharma pioneer significant vaccine research

Researchers have identified the potential of 7HP349 as an oral medication to strengthen the effectiveness of vaccines, particularly for populations that struggle with immunosuppression. The study suggests adding 7HP349 to standard vaccination can improve vaccine efficacy without reformulating the vaccine.

SourceTexas Heart Institute·Journalnpj Vaccines·TypeExperimental study·DateSep 14, 2021

Study shows decreased mortality for patients with complex aortic aneurysms treated by fenestrated-branched endovascular aortic repair

A recent study found that fenestrated-branched endovascular aortic repair significantly reduced mortality rates for patients with complex aortic aneurysms, with a 1% risk of mortality at 30 days compared to 21% in open surgical repair. The procedure also showed better outcomes regarding major adverse events, including spinal cord injury.