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The 'Signal Cell' relaying microbiota signals discovered

Researchers at Pohang University of Science & Technology discovered a mechanism by which microbiota signals are transmitted to the entire body, controlling hematopoiesis in the bone marrow. This process involves CX3CR1+ mononuclear cells recognizing microbiota signals and releasing cytokines that stimulate the immune system.

SourcePohang University of Science & Technology (POSTECH)·JournalBlood·DateNov 25, 2019

Autologous bone marrow-derived mononuclear cell transplants can reduce diabetic amputations

Researchers found that autologous bone marrow-derived mononuclear cell transplants can significantly induce vascular growth, reducing the number of amputations in patients with diabetes suffering from critical limb ischemia. The study showed a significant increase in neovasculogenesis and a decrease in PAD mortality.

SourceCell Transplantation Center of Excellence for Aging and Brain Repair·JournalCell Transplantation·DateApr 18, 2012
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