Articles tagged with Neurology
A study published in Neurology found that eating more ultra processed foods may speed up early signs of Parkinson's disease. Participants who consumed over 11 servings of ultra-processed food per day had a higher likelihood of developing three or more early symptoms of the disease.
A study published in JAMA Neurology found no evidence supporting a diagnosis of the New Brunswick neurological syndrome of unknown cause, highlighting the need for independent clinical evaluations. The data revealed presence of several neurodegenerative and non-neurodegenerative conditions instead
The Psychedelics journal has expanded its focus to include all psychoactive drugs, challenging traditional classifications and embracing a broader understanding of consciousness-altering substances. This move aims to reveal novel therapeutic applications and deepen human knowledge of the mind.
Researchers from the University of Texas at San Antonio discovered a significant link between REM sleep disturbances and increased PTSD severity. The study suggests that targeting REM sleep could be a promising approach for improving PTSD treatment outcomes.
Researchers develop specialized enzymes to selectively increase or decrease specific mutation loads in mitochondria, allowing precise study of disease manifestation. This technology holds promise for treating patients with mitochondrial diseases by reducing mutant mtDNA load.
Researchers at UCSF found clinically significant improvements in mood, cognition, and motor function after psilocybin therapy for patients with mild to moderate Parkinson's disease. The study suggests that psilocybin could provide relief from multiple symptoms of the disease by reducing inflammation and promoting neuroplasticity.
Researchers at Amsterdam UMC have developed a new diagnostic test that measures CRP protein in cerebrospinal fluid to quickly diagnose bacterial meningitis. The test has been shown to be very reliable and can start treatment within half an hour of diagnosis.
A new brain-inspired algorithm developed at BU can help hearing aids tune out interference and isolate single talkers in a crowd of voices. In testing, researchers found it could improve word recognition accuracy by 40 percentage points relative to current hearing aid algorithms.
Research finds that 40Hz sensory stimulation promotes broad-based restorative neurological health response in mice with Down syndrome. The study shows improved cognition, increased neural activity, and enhanced neurogenesis, suggesting potential therapeutic benefits.
Researchers at the University of Calgary investigate the effectiveness of transcranial magnetic stimulation combined with intensive speech therapy for treating poststroke aphasia. The study found significant improvements in speech, confidence, and mood among participants, offering new hope for those affected by stroke.
A significant proportion of patients who suffer a stroke due to carotid artery narrowing can be treated with medication only. Researchers found that up to 75% of patients may not need surgery, eliminating the risk of another stroke and saving healthcare costs.
Severe RSV disease among children is more likely those aged 2 or older with pulmonary or neurologic conditions. Younger children under 6 months and prematurity are high-risk factors for severe RSV in younger kids.
A new analysis finds a significant increase in people dying at home due to ischemic stroke, reversing a 10-year decline, with rural communities and Black Americans more likely to die in less specialized care environments. The study also reveals rising death rates from stroke, despite improvements in access to palliative care.
Researchers found that mouse brains process active and passive touch through different pathways, with one region responding to surprise at touch. This distinction may help mice navigate their environments more effectively.
Research reveals that GLP-1RAs and SGLT2i medications significantly reduce the risk of Alzheimer's disease and related dementias in people with type 2 diabetes. No significant difference was found between these two treatments.
Researchers at Temple University have discovered a new way to block the enzyme DLK, which plays a key role in neurodegenerative diseases. The breakthrough approach protects damaged neurons while preserving healthy neuron function.
A global study led by UCalgary researchers found that one in five people who experience a minor stroke or TIA will have another stroke within 10 years. The study analyzed data from over 171,000 patients across four continents and shows a persistently high risk of future strokes for at least a decade.
Cognitive neuroscientists are using VR to develop innovative ways to assess cognitive decline, particularly in identifying age-related differences in spatial memory navigation. The study found significant impacts on memory performance due to the build-up of Alzheimer's proteins in the brain.
The study used AI analysis on over 4,200 clinical reports to identify key factors in autism diagnosis. Criteria related to repetitive movements and special interests were strongly linked to an autism diagnosis, while socialization criteria were not highly specific.
A new review article identifies major themes in AI application to neurosciences, including a 5-fold increase in AI-related publications. The study also notes a surge of over 13-fold in clinical neurology AI-related publications in the past decade.
A recent study by the University of Eastern Finland found that elderly neurological patients are willing to accept remote monitoring in their homes. The study identified factors such as family caregiver presence and educational level as determinants of RM acceptance.
A review article reveals CD2AP's crucial role in amyloid metabolism, tau pathology, synaptic function, and neuroinflammation in Alzheimer's disease. CD2AP deficiency accelerates plaque formation, while its loss in neurons leads to reduced spine density and impaired synaptic plasticity.
The Open Brain Institute launches a groundbreaking platform to simulate and study digital brains, empowering researchers to explore brain complexity and diseases. With its virtual neuroscience laboratories, the OBI enables global collaboration and access to cutting-edge virtual labs.
A University of Illinois Chicago study reveals that intranasal herpes infection can cause severe neurobehavioral symptoms, including anxiety and cognitive issues. The research suggests that the virus exploits a cellular enzyme to produce behavioral symptoms, emphasizing the need for prevention and treatment.
Researchers at UC San Francisco have enabled a paralyzed man to control a robotic arm through a device that relays signals from his brain to a computer. The device, known as a brain-computer interface (BCI), worked for a record 7 months without needing to be adjusted.
Researchers discovered that females' dormant X chromosome reactivates in late life, expressing genes related to brain development and cognitive health. This phenomenon may explain why women outlive men and retain their cognitive abilities longer.
Dr. Guy Rouleau, a renowned geneticist and neurologist, has founded the world's first academic institution committed to open science principles. The Neuro institute aims to transform how brain disease research is conducted worldwide by promoting data sharing and collaboration.
Studies have consistently shown that 40Hz gamma stimulation can improve cognitive function and reduce Alzheimer's pathology in mice. In human clinical trials, participants exposed to 40Hz light and sound experienced significant slowing of brain atrophy and improvements on some cognitive measures compared to untreated controls.
Researchers identified pathogenic thresholds for the CAG repeat units (RU) of the CACNA1A gene that causes SCA6. They found that over 90% of cases with 21 or more RU fell within a predicted age range. The study has important implications for SCA6 diagnosis and genetic counseling.
A new study finds that dexamethasone, a commonly prescribed anti-swelling drug, can significantly reduce the body's immune response to brain cancer for weeks after its last dose. This effect is stronger with higher dosages and may impact immunotherapy treatments.
A study found that 10% of South Asian immigrants aged 45 and older in Canada had hypothyroidism. Higher dietary intake of fat, lower consumption of fruits and vegetables, and increasing age were associated with a higher risk of the condition. Early recognition and treatment are crucial to minimize preventable health impacts.
Research reveals misplaced neurons in the brain are overactive due to mutations in gene DCHS1, causing periventricular heterotopia. These neurons have altered synaptic connections and complex morphology, leading to hyperactivity that can be reversed with antiepileptic drug Lamotrigine.
A recent MSU study highlights the challenges of diagnosing episodic disabilities like epilepsy, where symptoms fluctuate and can be unpredictable. The research found that 52% of participants experienced delayed diagnoses, while others faced quick confirmations within days of their first seizure.
A new study published in Annals of Neurology found that lower concentrations of vitamin B12 in healthy, older adults led to signs of neurological and cognitive deficiency. These individuals showed slower processing speeds, brain lesions, and delayed responses to visual stimuli compared to those with higher B12 levels.
A recent study explored the neurologic impact of flu in children and found that serious neurologic events are almost 50 times more common in those with underlying neurologic conditions. The study highlights the need for improved vaccination and treatment efforts targeted towards vulnerable children.
A study of 153 people between the ages of 60 and 89 suggests a modification to the well-established clinical test for assessing balance in the elderly to make it more efficient, accessible, and predictive. The assessment can predict the risk of falling over a six-month period with accuracy.
Researchers examine how stroke patients develop post-stroke sensory reweighting (PSR) to improve walking and balance. PSR is a critical factor in determining patient outcomes, with those who develop it experiencing better balance and reduced risk of falls.
UCalgary researchers confirm that endovascular thrombectomy (EVT) is not effective for patients with blockages in medium-sized blood vessels. The ESCAPE-MeVO clinical trial found no improvement in outcomes for these patients compared to standard care. EVT was previously shown to improve patient outcomes after large-vessel strokes.
A cohort study reveals a robust association between headache diagnoses and suicidal behavior, highlighting the importance of behavioral health evaluation and treatment for these patients. The findings suggest that patients with headache diagnoses should be screened for suicidal ideation and provided with appropriate support.
A preliminary study presents a link between stroke and mental health challenges in children, highlighting the need for early intervention and screening. The analysis found that kids who have a stroke are at higher risk of developing anxiety, depression, and related physical symptoms.
Researchers have developed a blood test that can rapidly distinguish between brain bleeds and clot-caused strokes, even before patients arrive at the hospital. This test uses glial fibrillary acidic protein (GFAP) levels to differentiate between hemorrhagic and ischemic strokes, which can lead to opposite treatments.
Researchers developed a novel cortical biomarker signature to predict individual pain sensitivity, showcasing high accuracy and reproducibility. The study suggests this biomarker has substantial potential for clinical translation in predicting chronic pain transitions.
Researchers found that patients undergoing mechanical thrombectomies at smaller hospitals did not have less favorable outcomes than those at large healthcare systems. In fact, larger hospitals with higher volumes of procedures saw more adverse outcomes in stroke patients.
A brain-computer interface has enabled a person with tetraplegia to control a virtual quadcopter by thinking about moving their unresponsive fingers. This technology provides unprecedented control, allowing the user to maneuver through a virtual obstacle course and potentially enabling remote work and social interactions.
A new study published in Neurology found that eating greater quantities of red meat, especially in processed forms, increases the risk of dementia. Replacing processed red meat with protein sources like nuts and legumes or fish may decrease dementia risk by approximately 20 percent.
Researchers studied rats navigating an L-shape track with a food-guarding robot. The rats created neurological maps of places to avoid after experiencing negative events and thought about these locations even after leaving the area. This finding provides insight into the neuroscience of common psychological conditions like anxiety.
Researchers developed a predictive tool using the Florey Dementia Index to forecast onset ages of mild cognitive impairment and Alzheimer's. The validated tool may help prioritize patients for disease-modifying treatments.
A new study finds that women with gestational hypertension and preeclampsia are at increased risk of developing new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue after giving birth. Follow-up care is recommended for these high-risk patients to monitor for neurological symptoms.
The National Institute of Neurological Disorders and Stroke has awarded researchers at the University of Tennessee Health Science Center $2.18 million to investigate a new small molecule that activates SERCA2, aiming to correct calcium imbalances caused by diabetes after a stroke.
A clinical trial showed that an antibody blocking Nogo-A protein improves motor function in patients with incomplete spinal cord injuries. The treatment led to significant improvements in voluntary muscle activation and everyday life functional independence. Further studies are needed to confirm the findings.
A USC study reveals that forming social ties relies on learning from positive outcomes, such as rewards, and tracking relational value. The findings help explain why we are drawn to certain people and how we navigate relationships, with implications for mental health and social behavior.
A study published in JAMA Network Open found that hospital-acquired pressure ulcers are associated with poorer neurological outcomes and reduced motor function in patients with acute cervical spinal cord injury. The findings suggest that preventing pressure ulcers can help protect these patients and lead to improved medical care.
A new study published in the Journal of the American Heart Association found that Mexican American women are more likely to miss prescribed doses of stroke prevention medications. The study highlights sex-associated disparities in stroke care, particularly among racial and ethnic minorities.
A team of researchers from Mass General Brigham has identified changes in immune cells that can predict patient recovery after cardiac arrest. The study suggests that a particular population of cells may provide protection against brain injury and a drug that can activate these cells, improving neurological outcomes in preclinical stud...
A Phase 2 trial evaluated L-arginine's efficacy and safety in patients with spinocerebellar ataxia type 6, showing a mild improvement in ataxia symptoms. However, the treatment effect was not statistically significant, requiring further investigation to confirm its effectiveness.
A new study will evaluate the benefits and risks of endovascular thrombectomy for patients presenting beyond 24 hours. The trial aims to provide deterministic evidence of clinical benefit due to addition of endovascular thrombectomy to standard medical care.
A cohort study found that long-term exposure to wildfire and fine particulate matter was associated with dementia diagnoses. The study suggests that reducing wildfire PM2.5 exposure could decrease dementia diagnoses and address health disparities.
A new approach profiles gene activity in the living brain, providing insights into neurological conditions like epilepsy. The study enhances understanding of seizure networks, potentially improving surgical interventions.
New research highlights additional therapies being tested for hypoxic-ischemic encephalopathy (HIE) in newborns, including agents blocking glutamate receptor activation and antioxidant drugs. While therapeutic hypothermia is effective in high-income countries, its efficacy is uncertain in low- and middle-income nations.
Researchers aim to shed light on how hearing impairment affects auditory perception, particularly in complex environments. They will use animal models to examine neural mechanisms contributing to difficulties in sound localization.