Articles tagged with Neutrophils
Researchers found that phagocytes reduce IL-23 production after ingesting apoptotic neutrophils, leading to decreased inflammatory response. Abnormal neutrophils with impaired migration resulted in elevated IL-23 and IL-17 levels.
A Stanford study found that infusing bone marrow cells from a donor mouse into laboratory mice before chemotherapy can significantly improve their ability to fight infections and survive. This new approach boosts neutrophil production, reducing the risk of neutropenia-related complications.
Neutrophils can produce NETs, a net-like structure that binds, disarms, and kills bacteria. This novel defense mechanism was discovered by researchers at the Max Planck Institute for Infection Biology.
Researchers at the NIH/NIAID have discovered that streptococcal infections trigger altered gene expression in neutrophil white blood cells, exposing potential targets for new treatments. The findings provide insight into how these common bacteria evade immune defenses.
Researchers at Scripps Research Institute have found that the human body produces ozone as part of a mechanism to protect itself from bacteria and fungi. The discovery suggests a new role for neutrophils and antibodies in the immune system, potentially leading to new treatments for inflammatory diseases.
Researchers uncover the role of parasympathetic innervation in fat distribution, revealing functional implications for obesity. Additionally, studies explore the molecular mechanisms behind long QT-3 syndrome, immunodeficiencies, and intestinal lymphocyte recruitment, shedding light on novel therapeutic targets.
Scientists have identified a mechanism by which neutrophils can neutralize disease-causing bacteria like Shigella and Salmonella. Elastase, an enzyme produced by neutrophils, destroys virulent proteins in bacteria, allowing for the mobilization of other defenses that can destroy the bacteria.
Myeloperoxidase (MPO) produces nitrotyrosine in the subendothelial space, indicating oxidative damage to endothelial cells. This finding suggests MPO may contribute to vascular dysfunction and cardiovascular disease.
A diet rich in seafood, particularly eicosapentaenoic acid, has been shown to reduce the production of leukotriene B4, a molecule that promotes inflammation in rheumatoid arthritis patients. This reduction leads to less inflammatory effects and a decrease in neutrophil migration and release of damaging molecules.