Articles tagged with Adenosine Triphosphate
Researchers found that old mitochondria are leaky, reducing ATP production and making normal activities challenging for the elderly. This inefficiency affects muscle cells' ability to produce useable energy.
Researchers discovered that failing hearts experience an energy deficit due to a 50% reduction in ATP energy supplied by creatine kinase. This finding suggests new treatments may target the energy supply to improve heart function.
Researchers at Johns Hopkins Medicine have identified a second source of phosphate in cells, inositol pyrophosphate (IP7), which modifies proteins without ATP's help. IP7's role in regulating brain chemicals and protein synthesis suggests new potential treatments for neurodegenerative diseases.
NIST has awarded up to $80.1 million in funding for 32 new advanced technology program (ATP) projects, spanning various key technology areas including energy, medical diagnostics, electronics, and computer interfaces. The projects aim to improve productivity, facilitate trade, and enhance quality of life.
The 'shoelacing' technique allows for quick activation of emergency phone service by connecting surviving phone system links and Internet links. By the end of the ATP project in Spring 2005, TeleContinuity plans to develop an enhanced version with advanced Web-based controls.
Researchers genetically engineered mice to enhance endurance by altering muscle fiber types. These changes improved running performance, but also led to muscle damage when pushed too far. Additionally, a new technique using PPARα protein transformed slow-twitch fibers into fast-twitch fibers, increasing exercise time and distance.
Researchers discovered that excess ATP damages motor neurons, leading to paralysis. Blocking ATP's effects restored function in rats with damaged spinal cords, opening up promising new avenues for treatment.
The updated report recommends lower LDL cholesterol levels as a direct relationship with reduced risk for major coronary events. Therapeutic lifestyle changes are also emphasized for cholesterol management.
Researchers found that condensin proteins cause DNA to extend in stepwise 'clicks' like Velcro unzipping, with the process reproducing identically every time. The energy-containing molecule ATP plays a regulatory role, allowing the bound protein to recondense DNA when tension is lowered
Researchers identify torsinA, a protein defective in DYT1 dystonia, and discover its role in the nuclear envelope. The study provides new insights into potential treatments for movement disorders and secondary dystonias.
Researchers have found that deliberate damage to sensory receptor cells in the inner ear can trigger a cascade of signals through ATP release, leading to the spread of calcium ions. This mechanism is activated by loud noise levels commonly experienced in nightclubs and when using personal headphones.
The National Institute of Standards and Technology (NIST) is holding a single competition for Research and Development (R&D) projects, with approximately $30 million in funding available. Public meetings will be held across the country to provide information on the competition, project selection criteria, and eligibility requirements.
A study by University of Iowa researchers reveals that the cystic fibrosis protein CFTR can function as an adenylate kinase enzyme, controlling channel opening without consuming energy. This discovery has broad implications for understanding ABC transporters and their role in genetic diseases.
A new technique using a modified ink-jet printer and semiconductor ink has been developed to produce transistor arrays for flat-panel displays. The process reduces the cost of display manufacturing by replacing expensive photolithography techniques, enabling flexible and rigid substrate applications.
A team of researchers led by Dr. Sharyn Endow at Duke University Medical Center has discovered the power stroke that drives molecular motors, which transport nutrients around cells or herd chromosomes during cell division. This breakthrough could help understand diseases like Down's syndrome and prevent them.
Purdue University researchers have discovered how RNA molecules bind energy-bearing ATP molecule, enabling physical work and potential applications in nanotechnology. The discovery sheds light on RNA's role in creation of living things and may unlock new methods for delivering therapeutic molecules.
Gene Network Sciences will use the federal grant to learn how pharmaceuticals work against cancer cells, creating computer models to identify nontoxic drug targets. The company aims to make drug-discovery more predictable for pharmaceutical and biotech companies with its new technology.
Researchers at Cornell University have successfully demonstrated hybrid nanodevices that can administer drugs and treatments using biomolecules and tiny nickel propellers. The devices are powered by ATP and can be assembled, maintained, and repaired using life's physiology.
Scientists at Johns Hopkins Medicine solved a major mystery surrounding energy production by determining the molecular structure of adenosine triphosphate synthase (ATP synthase). The discovery explains how cells produce ATP, the common currency of energy, and offers new insights into why people get less energetic with age.
Researchers at Oregon Health & Science University found that adenosine triphosphate (ATP) stimulates pain-sensing nerves by binding to a receptor called P2X3 on nerve cell membranes. This discovery may pave the way for the design of new pain-relieving drugs.