Articles tagged with Catalytic Subunits
Researchers found that suppressing AMPKα1 but not AMPKα2 isoforms improved aging-related impairments in mice. The study revealed novel insights into the roles of AMPK signaling pathway in cognitive aging.
Researchers from Northwestern University discuss the multifaceted tumorigenic functions of EZH2, including its role in regulating translation and coactivating transcription. This new understanding may provide novel insights into advancing EZH2-targeting strategies for prostate cancer patients.
Researchers at Max Planck Institute successfully revived ancient enzymes, revealing a novel protein component that increased CO2 specificity in Rubisco. This discovery provides new insights into the evolution of modern photosynthesis and suggests adding new components may improve its efficiency.
The Max Delbrück Center researchers identified a new layer of PKA regulation through the binding of ARHGAP36 to its catalytic subunit. This interaction can inhibit PKA's kinase action, and its expression is limited to embryonic muscle cells and certain types of cancer.
Researchers at UCSD School of Medicine have solved the structure of protein kinase A, a key enzyme involved in memory formation, nerve cell communication, and cardiac function. The study reveals how PKA is inhibited and activated by cyclic AMP, shedding light on its role in cardiac disease and breast cancer.