Articles tagged with Fatty Acids
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The University of Basel researchers have solved the mystery of how the ACC enzyme assembles into distinct filaments, revealing its impact on enzymatic activity and fatty acid production. This discovery opens up new possibilities for developing selective ACC inhibitors to combat diseases linked to metabolic syndrome.
A study found that increasing omega-3 fatty acids in mothers during pregnancy and lactation reduced weight gain and metabolic disruptions in infant mice fed a high-fat diet. This suggests that a balanced ratio of omega-6/omega-3 fats is critical for reducing the lifetime risk of obesity in children.
Researchers at Michigan State University have identified how MRSA absorbs human fatty acids to resist antimicrobials, providing a new target for developing more effective treatments. By inhibiting the cell membrane's ability to produce lipids, scientists may improve the efficacy of existing antibacterial agents like triclosan.
Researchers find that many invertebrates, including corals and molluscs, can produce omega-3 fatty acids through enzymes called desaturases. This breakthrough challenges the long-held principle that marine microbes are responsible for primary production of omega-3.
Recent studies in the Journal of Lipid Research reveal that dietary lipids can either treat or exacerbate diseases, depending on their type. The ketogenic diet has shown mixed results as a cancer therapy, while polyunsaturated fats like omega-3 and omega-6 have different effects on inflammation and brown fat formation.
Researchers found that diets high in plant-based mono-unsaturated fats were associated with a lower risk of death from heart disease and other causes. In contrast, diets rich in animal-based mono-unsaturated fats were linked to a higher risk of death from these causes.
A new study from the University of Eastern Finland found that high levels of omega-6 fatty acids in the blood are associated with a lower risk of premature death. The research also showed that this association is not limited to cardiovascular disease, but may also apply to other conditions such as diabetes.
Researchers at Nationwide Children's Hospital found clinically significant improvements in ASD symptoms in toddlers who received a daily omega fatty acid supplement. The study suggests that omega fatty acids may help reduce inflammation and improve behaviors in children with ASD symptoms.
A study suggests that consuming fish rich in omega-3 fatty acids, such as salmon and sardines, may lower the risk of multiple sclerosis. Researchers found a 45% reduced risk of MS among those with high fish intake compared to those with low or no fish consumption.
Research shows that cows fed a 100% organic grass and legume-based diet produce milk with elevated levels of omega-3 and CLA, improving the fatty acid profile. This results in a near-perfect balance of omega-6 and omega-3 fatty acids, beneficial for cardiovascular and metabolic diseases.
Researchers found a clear link between low arachidonic acid levels and retinopathy of prematurity (ROP) in extremely premature babies. Providing the children with arachidonic acid may help reduce the risk of ROP and minimize blindness.
A University of Guelph study found that omega-3s from fish are eight times more effective at inhibiting tumour development and growth compared to plant-based options. The research suggests that marine-derived omega-3s can significantly reduce breast cancer risk, particularly in aggressive forms.
Researchers discovered that a shift from fatty acid to carbohydrate-based energy sources can lead to congestive heart failure. The study identified Notch-1 receptor as key player controlling transport of fatty acids into cardiac muscle tissue.
Researchers discover active life in a frozen Quebec lake, with tiny red zooplankton buzzing in the dark water. The bright red coloration serves as protection against oxidative stress and helps the copepods accumulate essential fatty acids.
High levels of polyunsaturated fatty acids, particularly omega-3 and arachidonic acid, are associated with a reduced risk of asthma and rhinitis in children. The study found that children with higher blood levels of these fatty acids at age 8 were less likely to develop the diseases by age 16.
Researchers at Columbia University developed a new microscopy technique to track fatty acids in living cells, revealing that saturated fats cause hardened membrane patches that can lead to cellular damage. In contrast, unsaturated fats can 'melt' these patches, suggesting potential therapeutic strategies for lipid disorders.
A new study from the University of Eastern Finland supports earlier findings that omega-6 fatty acids do not increase inflammatory responses. The research found that a high serum linoleic acid level is associated with lower CRP levels, suggesting that linoleic acid may actually alleviate inflammation.
A study found that increasing omega-6 to omega-3 ratios in the diet were associated with SLE disease activity. Intake of omega-3 fatty acids was also linked to better sleep quality and trended toward significant decreases in depressive symptoms.
A recent study published in Molecular and Cellular Biochemistry found that brain cells contain less polyunsaturated fatty acids compared to other major organs. This discovery, made by Dr. Junhwan Kim, PhD, has significant implications for understanding brain health and conditions like oxygen deprivation.
Researchers at LSU Health Sciences Center have discovered a new class of molecules called elovanoids that synchronize cell-to-cell communication and reduce inflammation in the brain. These novel molecules, made from omega-3 fatty acids, protect neuronal cells and promote their survival.
Researchers discovered that promoting T cells to use fat as energy instead of glucose increases their antitumor activity and improves T cell function within tumors. This metabolic shift also enhances the efficacy of immune checkpoint blockade therapy.
Researchers identified a signaling pathway in liver cells that contributes to fatty liver disease in obesity. The study found that increased Fas content leads to liver steatosis and insulin resistance, while low BID content protects against fatty liver development.
Recent research from NTNU found that omega-3 fatty acids can dampen harmful inflammatory reactions in the body, particularly by activating autophagy and inhibiting interferon response factors. This may be beneficial for patients with conditions driven or aggravated by strong inflammatory responses.
Researchers found an enzymatic pathway that converts omega-3-derived endocannabinoids into potent anti-inflammatory molecules, which bind to receptors in the immune system. This discovery demonstrates how omega-3 fatty acids can produce medicinal qualities similar to marijuana without a psychotropic effect.
A recent study by the University of Otago found that regular brisk walks and daily longer walks significantly lower levels of fatty acids in office workers' blood. This approach may improve metabolic health outcomes and reduce the risk of cardiovascular disease and death.
A Clemson University graduate discovered that certain toxicants can disrupt the maturation of Daphnia magna by altering lipid levels, affecting development and reproductive rates. The study found that triclosan and atrazine can lead to stunted growth and altered lipid allocation in newborns.
A new study found that camelina seed yields were 54% lower at Hays than at Moccasin due to environmental conditions. However, seed protein content was significantly higher at Hays, and oil composition differed between the two test sites.
Researchers have discovered that naturally occurring fatty acids can switch off the specific genes that make listeria bacteria dangerous. Omega-3 fatty acids took about half an hour to neutralize the bacteria, according to the study published in Research in Microbiology.
Researchers found correlations between blood levels of omega-3 fatty acids and fluid intelligence in healthy elderly adults, suggesting a potential role for dietary intake of these nutrients. The studies also linked the balance of omega-3 and omega-6 fatty acids to memory preservation and brain structure.
Researchers at Carnegie Institution develop a method to visualize and measure lipids in real-time as they are metabolized by living fish. This breakthrough allows for a better understanding of cellular functions and the role of lipids in health problems such as cardiovascular disease and diabetes.
A new study published in Diabetologia found that high levels of fish-derived fatty acids, particularly DHA and DPA, were associated with a lower risk of early autoimmunity in infants at high genetic risk for type 1 diabetes. Breastfeeding was also linked to higher serum levels of protective fatty acids.
Researchers have designed a nickel catalyst that transforms unrefined hydrocarbons and CO2 into pure fatty acids at room temperature and atmospheric pressure. This sustainable process has significant implications for the environment and could alleviate economic concerns in the production of fatty acids.
Researchers found that knocking out a key enzyme improved post-heart attack healing and reduced chronic inflammation. The study suggests that a short-term dietary excess of polyunsaturated fatty acids may also play a role in promoting healing.
A new study found that supplements of DHA, an essential omega-3 fatty acid, can prevent the progression of nonalcoholic steatohepatitis (NASH) into more serious health problems like cirrhosis and liver cancer. This breakthrough discovery offers hope to millions of people worldwide who struggle with obesity and poor diet.
A study published in Scientific Reports found that a high-fat, high-carbohydrate diet rich in saturated fatty acids can weaken cartilage in joints, leading to osteoarthritis. The research suggests that diet may play a significant role in the onset of osteoarthritis, rather than wear and tear.
A new study found that areas with trans fat bans in restaurants had significantly fewer hospitalizations for heart attack and stroke compared to areas without restrictions. The decline was 6.2%, highlighting the power of public policy to impact cardiovascular health.
A new study published in PLOS One found a significant correlation between the consumption of n-6 polyunsaturated fatty acids (PUFAs) and sedentary behavior in pre-teen girls. The research also suggests a weak association between PUFA intake and diabetes risk among adult women in Europe. Researchers recommend further studies to confirm ...
A mouse experiment revealed that hydroxytyrosol, a compound found in extra-virgin olive oil, can reverse markers of insulin resistance and non-alcoholic fatty liver disease. The study showed that hydroxytyrosol exerts a protective effect in the liver by improving enzyme activity and fatty acid composition.
A new study from Ohio State University suggests that body weight plays a significant role in the effectiveness of omega-3 fatty acid supplements in children. The researchers found that the more a child weighed, the smaller the measurement was of key omega-3 fatty acids in their bloodstream.
Research suggests that omega-3 fatty acids can diminish inflammatory processes contributing to type 1 diabetes. Increasing omega-3 FA consumption improved glucose metabolism and reduced diabetes occurrence in a mouse model.
A team at Chalmers University of Technology has developed a novel method to modify the fatty acid synthase enzyme, producing medium chain fatty acids and methyl ketones for transportation fuels. The breakthrough enables the production of sustainable biofuels in yeast cell factories.
A study published in Journal of Clinical Investigation--Insight found that omega-3 fatty acid products can reduce IgE production, a common allergen responsible for asthma symptoms. However, patients with severe asthma who rely on high-dose oral steroids may not benefit from fish oil supplementation.
Researchers found that S6K1 phosphorylation mediates the transport of fatty acids, contributing to adiposity and aging. Mice with deficient EPRS showed similar physical characteristics to those with deficient S6K1, suggesting a dual role for S6K1 in obesity.
Researchers found olfactory receptors in human heart muscle that react to fatty acids, reducing heart rate and contraction force. A blocker for the receptor has been developed to mitigate negative effects on diabetic patients and those with increased heart rates.
Researchers at the University of Jena discovered that naturally occurring fatty acids have a predictable number of structural formulas based on their chain length, following the Fibonacci sequence. This discovery enables accurate analytical processes in lipidomics, the study of all fats in cells and organisms.
A study by the Centre for Addiction and Mental Health estimates that nearly 10% of women drink alcohol during pregnancy worldwide, leading to an estimated 119,000 cases of Fetal Alcohol Syndrome annually. The study also found that nearly 15 people per 10,000 have FAS globally.
A large study published in The BMJ found that high intake of major saturated fatty acids increases the risk of coronary heart disease. Replacing these fats with polyunsaturated, monounsaturated, or plant-based sources can reduce this risk by 6-8%.
A new study led by Harvard T.H. Chan School of Public Health researchers found that consuming high amounts of four major saturated fatty acids increases the risk of coronary heart disease. Replacing these fats with healthier alternatives, such as whole grains and plant proteins, may reduce this risk.
Researchers at UAB found that a Mediterranean-style diet can reduce heart inflammation and failure in aged mice, as opposed to a Western-style diet high in omega-6 fatty acids. The study identifies key lipid signaling pathways involved in the disease process.
Researchers found a positive correlation between omega-3 fatty acid levels and lower systolic and diastolic blood pressures. Eating diets rich in omega-3 foods could be a strategy to prevent high blood pressure.
A study by Washington University School of Medicine researchers found that blocking the production of fat inside immune cells may prevent chronic inflammation in people with diabetes. This could have a profound impact on health and potentially lead to new treatments for cancer and other conditions.
Including canola oil in a healthy diet may reduce visceral fat in just four weeks. Monounsaturated fats in canola oil specifically target abdominal fat, reducing the risk of cardiovascular disease and metabolic syndrome.
Research suggests that omega-3 polyunsaturated fatty acids can enhance the glymphatic system, facilitating clearance of waste from the brain, including amyloid-β peptides. This improvement may provide benefits for neurological diseases such as Alzheimer's, traumatic brain injury, and sleep impairment.
The BMJ Group recommends restoring the correct dietary balance of omega 6 and omega 3 fatty acids to combat soaring obesity rates. The current ratio is 16:1, whereas human evolution suggests a healthier balance of 1:2/1. This imbalance promotes inflammation, white fat tissue, and chronic diseases linked to obesity.
Researchers investigate how exposure to chemicals inhibits metabolism of fatty and high-sugar foods, contributing to obesity. The team aims to understand how toxicants affect cytochrome P450 enzymes, potentially identifying new targets for pharmaceutical companies.
Researchers found that omega-3 fatty acids reduced brain damage in mice with hypoxic-ischemic brain injury. The study suggests that injecting DHA after a stroke-like event can protect brain mitochondria against free radical damage.
A large population-based study from Uppsala University found a strong correlation between linoleic acid in adipose tissue and lower mortality among older men. The study suggests that consuming more polyunsaturated fats may reduce the risk of premature death.
A large-scale study found that consuming at least 500mg of dietary omega-3 fatty acids daily was associated with a 48% reduced risk of developing sight-threatening diabetic retinopathy. The study, published in JAMA Ophthalmology, involved over 3,500 adults with type 2 diabetes and followed them for six years.
A new study has discovered that fatty acids on water droplets react with sunlight to form organic molecules, challenging conventional wisdom. This process could significantly impact local ozone and particle formation, affecting climate, air quality, and health.
A team from Washington University in St. Louis has developed a new method to produce biofuels in E. coli bacteria, boosting BCFA manufacture to 80 percent of all fuel products, and opening up potential applications for pharmaceuticals and other useful products.