Articles tagged with Fatty Acids
A study published in Nature Metabolism suggests that a Western high-fat diet can increase the risk of painful disorders, such as arthritis and diabetes-related neuropathic pain. By altering diet or developing drugs that block fatty acid release, chronic pain patients may find relief.
Researchers at Duke-NUS Medical School have made significant breakthroughs in understanding the transport of omega-3 fatty acids across the blood-brain barrier. The study revealed the structure and function of a protein called MFSD2A, which plays a crucial role in delivering essential fatty acids to the brain.
Researchers found that omega-3 fatty acids can reduce depressive symptoms by preventing cell death and promoting neurogenesis. The study used a combination of laboratory and patient research to identify the molecular mechanisms involved in this relationship.
Researchers at Université catholique de Louvain discovered that DHA slows the development of tumors by poisoning cancer cells through a phenomenon called ferroptosis. This mechanism is triggered when acidotic tumor cells absorb excessive amounts of unsaturated fatty acids, leading to cell death.
Researchers at Chalmers University of Technology have developed a dipping solution that significantly extends the storage time of fish side streams, increasing their value as food ingredients. The solution covers the surface with antioxidants, reducing oxidation and keeping quality high.
Research found that adolescents with higher levels of DHA, an omega-3 fatty acid, were less likely to develop psychotic disorder in early adulthood. Those with lower levels of DHA had a higher risk of developing the condition, even after accounting for other factors.
A study in the Peruvian Amazon reveals that declining fish biodiversity poses a significant risk to human nutrition, particularly for iron and essential fatty acids. The researchers predict that a tipping point will be reached when 40 of 60 food species become scarce or extinct, leading to a nosedive in nutritional value.
Brazilian researchers found that feeding cows soybean and linseed oils improves the quality of their milk by reducing saturated fatty acids and increasing unsaturated fats. The study showed an optimal omega-6/omega-3 ratio of 2.7:1, beneficial for human health.
A new study found that fatty acid supplements may protect children with high cholesterol from heart disease by increasing their blood levels of healthy omega-3 fatty acids. The researchers discovered that an EPA supplement improved the lipid profile in the blood, reducing the risk of coronary artery disease and promoting healthy aging.
Researchers found people with higher omega-3 EPA and DHA blood levels lived longer than those with lower levels. A high Omega-3 Index, around 8% or higher, was associated with a 13% lower risk of death from all causes.
Researchers have identified a new light-driven enzyme, fatty acid photodecarboxylase (FAP), that converts fatty acids into alkanes and alkenes under blue light. The enzyme's complex photocycle drives this transformation, and its structure has been elucidated using serial femtosecond crystallography.
A UBCO research team found that maternal fat intake affects infant gut microbial communities, immune development, and disease risk. The study suggests that milk fat may improve protection against intestinal infections when combined with n-3 PUFAs.
Researchers have programmed microalgae to produce fatty acids of different lengths, creating a more flexible cell factory for producing industrially relevant oils. This breakthrough could lead to the development of designer oils with various fatty acid chain lengths.
A team of scientists, including French researchers, uncovers the operating mechanisms of FAP (Fatty Acid Photodecarboxylase), an enzyme that converts fatty acids into hydrocarbons using light energy. The discovery opens up new opportunities for sustainable biofuel production and fine chemistry applications.
Researchers at the University of Gothenburg found that free fatty acids in the blood trigger insulin release even at normal blood-sugar levels, contradicting the long-held hypothesis. The study suggests that obesity and excess fat tissue contribute to increased FFAs, which may be an early sign of incipient type 2 diabetes.
Researchers found that shorter brining times for Parmigiano Reggiano resulted in cheeses with 9% lower salt content and higher free fatty acids. The study suggests a reduced brining time could make the cheese more appealing to salt-conscious consumers.
A team of researchers from Korea has optimized a bioelectrochemical system (BES) to efficiently convert carbon dioxide and carbon monoxide into useful chemicals. The BES increases efficiency by 2-6 times that of current systems, producing acetate and volatile fatty acids.
A study on microalgae from the Kaliningrad Region revealed that Chlorella vulgaris and Dunaliella salina produce high amounts of saturated fatty acids, while Arthrospira platensis contains up to 23% unsaturated fatty acids. These findings suggest microalgae as a promising source for lipid production.
Synthesized very-long-chain polyunsaturated fatty acids (VLC-PUFAs) have been shown to increase lipid levels in the retina and improve visual function in both normal and defective ELOVL4 mice. The study opens up a new area of research, raising questions about oral administration, blood transport, and selective targeting to the retina.
Researchers uncover the reason behind reduced oil production in genetically modified plants producing specialty fatty acids. They found that feeding these plants additional endogenous fatty acids triggers a shutdown mechanism, slowing down oil synthesis.
A Swedish study found that administering a new supplement combining various fatty acids halves the risk of severe retinopathy of prematurity, which can cause blindness. The study showed significant reductions in severe retinopathy among extremely premature babies.
A new study suggests that consuming long chain omega-3 fatty acids in childhood can reduce the risk of developing asthma, but only in children with a specific genetic make-up. The research found a significant association between higher intake of long chain omega-3 fatty acids and lower risk of asthma.
A pilot study published in Prostaglandins, Leukotrienes and Essential Fatty Acids found that patients with higher omega-3 blood levels had a lower risk of death from COVID-19. The study showed that those in the highest quartile of omega-3 index were 75% less likely to die compared to those in lower quartiles.
The liver metabolizes coconut oil with medium-chain fatty acids, which are processed by DGAT1 enzyme, whereas long-chain fatty acids are processed by DGAT2. This knowledge could help treat certain diarrheal diseases by adjusting diet.
Researchers developed a method to detect pancreatic cancer by analyzing changes in albumin's structure and function. The approach showed promise in distinguishing between benign and malignant tumours, but further testing is needed.
A new Yale University study finds that a lack of oleic acid in fat tissue can trigger an abnormal immune response in multiple sclerosis. Introducing oleic acids into fatty tissue increased regulatory T cells, which can help combat the disease.
A recent study from the Cooper Center Longitudinal Study and FARI found that fish oil supplement use in the general population does not adversely affect LDL-C. In fact, higher RBC DHA levels are associated with a small decrease in LDL-C levels.
Engineers from Aarhus University and MIT have enabled the biological synthesis of high-yield industry-relevant production of climate-neutral drop-in fuels from biowaste using an unusual light-dependent enzyme. The discovery proves that fatty acyl-CoA is the preferred reactant for the enzyme, leading to a 89% conversion rate into alkanes.
Researchers found that targeting the fas protein can prevent cancer cells from escaping immunotherapies, leading to longer-lasting positive responses and improved survival rates. By combining immunotherapies with small molecule inhibitors, bystander tumor cell killing may be potentiated to eliminate antigen-loss variants.
A recent study from FARI and The Cooper Institute found a significant relationship between omega-3 levels and heart rate recovery, with higher levels linked to faster heart rate drop. This association was more pronounced in women than men and was associated with reduced risk of sudden cardiac death.
Biologists from RUDN University identified polymorphisms in six genes that determine flaxseed oil's fatty acid composition and shelf life. The study found specific gene variations that extend the shelf life of flaxseed oil, improving genetic selection for new flax breeds.
A daily dose of omega-3 fatty acids failed to reduce cardiac events, including secondary heart attacks and strokes, among elderly people who survived a recent heart attack. The OMEMI Trial found no significant difference in the rate of cardiac events between the two groups after 2 years of follow-up.
A recent study published in the American Heart Association's Scientific Sessions found that fish oil and vitamin D supplements did not increase or decrease the risk of developing atrial fibrillation. The trial involved 25,119 adults aged 50 and older and followed them for five years. No significant differences were found between those ...
A team of international chemists identified valuable fatty acids in seeds of two popular medicinal plants. The study found that these plant oils contain unsaturated conjugated fatty acids with anti-tumor properties and help combat obesity and inflammation.
A randomized clinical trial found that vitamin D, omega-3 fatty acid supplements, and strength-training exercise program improved blood pressure and cognitive function in older adults. The study also investigated the combination of these interventions, which showed even greater benefits.
A new equation for estimating glomerular filtration rate (GFR) shows improved accuracy and precision compared to commonly used equations. The European Kidney Function Consortium's (EKFC) equation addresses limitations of existing methods and is suitable for a wide age range.
Researchers will investigate the role of Cyp2b genes, human CYP2B6 gene, and environmental toxicants like PFOS in obesity and fatty liver disease. The study aims to understand complex interactions between diet, fat stores, and genetic factors.
Research found that warmer lakes support higher biomass of algal and cyprinid fish communities, while clear-water lakes have decreased quality of primary producers. Despite changes in prey item quality, fish biomass increased in murky lakes due to a shift towards roach-dominated communities.
A study found that consuming omega-3 fatty acids from both animal and vegetable sources strengthens the heart's membranes, improving prognosis in patients after a heart attack. High levels of these fats at admission were associated with lower risks of complications and mortality.
Researchers at Flinders University have developed a novel protocol to detect lipid production in microalgae, enabling the mass production of omega-3 fatty acids and other healthy compounds. The technique improves on traditional fluorescent probes, allowing for easy and rapid evaluation of lipid conditions within microalgae.
Lymphoma cells can resist therapy by evading apoptosis due to the presence of the Livin protein. Targeting Livin using inhibitors may be effective in refractory cases. Researchers have identified a promising immunotherapeutic strategy by combining CD40-mediated Fas expression with specific targeting of Livin.
Researchers developed a superior method to produce high-quality dietary Omega-3 health supplements using vortex fluidic device processing. The process enriches Omega-3 fatty acid content without changing sensory values, improving shelf life and purity.
Researchers at Kumamoto University found that activation of PPARα, a fatty acid receptor, causes masculinization of Japanese rice fish. The discovery may lead to improved fish farming techniques by controlling sex differentiation.
Fatty acid binding proteins (FABPs) are chaperones that coordinate fatty acid transport between cells. Research by University of Louisville immunologist Bing Li reveals their role in lipid metabolism, obesity, and disease development.
A new modular iridium catalyst allows unprecedented control over fatty acid derivative modification, enabling the production of valuable compounds from renewable resources. This breakthrough opens up new avenues for pharmaceuticals and plastics synthesis.
A high fructose diet in pregnant women can alter the metabolism of their offspring, researchers found. The study, published in Frontiers in Endocrinology, showed that fructose intake before and during pregnancy led to significant changes in maternal metabolic function and milk composition.
Research reveals the resolution of injury-induced inflammation is under dietary control, requiring a balance of hormonal and genetic factors. The diet can enhance or inhibit each step of the process, affecting healing outcomes.
Researchers studied how microbes in fermented sausages influence fatty acid production, revealing differences between microbe combinations. The study found that specific bacteria alter the composition of fatty acids, contributing to desirable traits like antifungal activity and flavor profiles.
KAUST researchers used high-speed imaging to observe collisions between air bubbles and water surfaces, finding that the air-water interface is more mobile than expected. The team also developed a method using thin films of fatty acids to immobilize free water surfaces, drastically reducing bouncing.
A new study found that older women who eat more fish may counteract the negative effects of air pollution on their brains. The research discovered a link between higher levels of omega-3 fatty acids and greater brain volumes, particularly in white matter and the hippocampus.
Researchers discovered that human milk contains a mix of saturated and polyunsaturated fatty acids, differing from bovids and primates. The study suggests that breast milk composition is evolving to meet the growing brain's needs, with increased polyunsaturated fatty acid content in human milk.
A new study by scientists from Martin Luther University Halle-Wittenberg found that microalgae farming has a similar environmental impact to fish production, but produces more omega-3 fatty acids per unit area. This could lead to a more sustainable source of essential nutrients for humans and reduce pressure on the world's oceans.
Researchers at TUM have developed a new method to quantify the key substances in chanterelles responsible for their distinctive kokumi effect. These natural fatty acid derivatives can be used as quality control markers and potentially improve flavor profiles in mushroom dishes and other savory foods.
The ApoE4 variant prevents the recycling of sortilin, a receptor that supplies neurons with essential fatty acids. This disruption leads to reduced lipid uptake and increased inflammation in brain cells, making them susceptible to cell death.
Researchers have identified Angiopoietin-2 as a hormone that enables the proper transport of fatty acids into blood vessels, preventing insulin resistance and promoting healthier weight distribution. By targeting this mechanism, scientists hope to develop novel therapeutic strategies for treating obesity-induced metabolic disorders.
Researchers found that moon jellyfish contain essential fatty acids like arachidonic acid and eicosapentaenoic acid, vital for predator growth and reproduction. This suggests that despite low caloric value, jellyfish can be an attractive prey item for predators through sheer quantity.
Researchers at the University of Illinois have developed a high-throughput screening tool to rapidly profile medium-chain fatty acids produced in yeast. They identified seven new genetically engineered mutants that produce higher levels of those fatty acids, which are crucial components of biodiesel and other industrial chemicals.
The study by UC San Diego researchers develops a scalable method to produce microalgae-based polyols from waste oils, creating valuable monomers for sustainable bio-plastics. The team also converts co-products into food flavoring and fragrance molecules, with economic value.
A study of 922 oocytes from obese and overweight women found lower concentrations of omega-3 fatty acids. The findings suggest that poor lipid composition in the ova may contribute to childhood and adult obesity.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that short-term cold exposure increased energy expenditure and improved fatty acid profiles in individuals with active brown fat. People with brown fat burned 15% more calories than those without, highlighting the organ's potential as a ta...