Jifeng Liu, a professor at Dartmouth's Thayer School of Engineering, has been named an OSA fellow for his work on renewable energy and reducing energy consumption in information technology. His research focuses on advancing solar technologies that are less expensive and more efficient.
This issue of Acta Pharmaceutica Sinica B features three original research articles exploring novel mechanisms and treatments for various diseases, including cerebral ischemia-reperfusion injury, anti-atherosclerosis, and breast cancer. The articles discuss the potential benefits of IL-4 supplementation, berberine's gut-absorption-enha...
The study demonstrated a paradigm shift in treating AML, proving that genetic information matching leads to better survival rates than traditional one-size-fits-all treatment. Patients who opted for precision medicine experienced lower early death rates and superior overall survival compared to those receiving standard of care.
Researchers developed artificial soil mixtures that mimic materials found on Mars, evaluating their fertility and potential for plant growth. The study found that Martian soils may be challenging to use due to textures and nutrient availability, but also identified potential solutions using Earth-based agricultural science.
Researchers have mapped the molecular structure of a potent COVID-19 antibody, CV30, which neutralizes the virus by interfering with its surface spikes and inducing critical pieces to break off. The antibody's unique shape allows it to overlap with the virus's target site on human cells, blunting its ability to infect.
The study found that repetitive cycles of wet-dry conditions led to progressive evolution of polymer compartments, affecting molecule exchange and composition. This research sheds light on prebiotic Earth and has implications for designing electronics and drug delivery systems.
Scientists have discovered a new RNA-centric mechanism that regulates the creation of a crucial cancer microRNA. The findings reveal that environmental stimuli can activate a 'hidden' layer of regulation, enhancing the efficiency of miR-21 processing and potentially leading to disease.
Researchers at UCI and CHUV/UNIL have developed a new cancer treatment that uses ultra-high dose rate radiation therapy to eliminate brain tumors without causing significant side effects. This breakthrough technique, known as FLASH-RT, has shown promising results in mice and has the potential to be used for a range of cancer types.
Researchers discovered specific metabolites that can distinguish COVID-19 patients from healthy participants and predict disease severity. Dietary supplements targeting these metabolites may also boost biochemical pathways, leading to improved health outcomes.
Research found a significant drop in death rates among severe COVID-19 patients in English hospitals between March and June. Death rates declined by half for both high dependency unit and intensive care admissions during this period.
Scientists have solved the Casimir puzzle by accounting for energy losses of conduction electrons in metals, leading to agreement between theory and high-precision measurements. The new approach takes into account both real and virtual fluctuations, enabling reliable calculation and creation of miniature nanodevices.
A study published in PLOS Biology found that individuals with autism spectrum disorder show reduced flexible behavior due to less optimal learning. The research used a developmental approach and examined flexible behavior on a probabilistic reversal learning task in children, adolescents, and adults with ASD.
Researchers studying COVID-19's impact on US college students aim to understand how the pandemic has disrupted their personal, educational, and economic plans. The study will examine decision-making styles, values orientation, and substance use/mental health patterns.
Researchers from the University of Tsukuba developed an infrared-transmitting polymer that retains its shape after stretching and can be used to fabricate lenses with variable-focus properties. The polymer is based on low-cost, sustainable materials and was found to transmit 10% of incoming infrared light.
A new technique has found extremely high stiffness in tiny regions of aggressive breast cancer tumors, suggesting only a few areas need to stiffen for metastasis to occur. This could lead to improved cancer detection and mapping.
New research extends Florida's hurricane record thousands of years back in time, hinting at a surprise finding. The study found that the state's Gulf Coast is hit by more intense hurricanes than its East Coast, with ancient tempest deposits suggesting this pattern may extend thousands of years back.
Researchers identified genes associated with decreased placental invasion and increased chemokine production in babies born with microcephaly. This finding provides insight into why only some babies exposed to Zika virus during pregnancy develop anomalies.
Researchers have developed a simple, environmentally friendly process to produce well-defined linear and star-shaped polymers with ultrahigh molecular weights from nonconjugated monomers. The photoenzymatic RAFT polymerization method offers outstanding control over composition, molecular weight, and architecture.
A new study found that coronaviruses use mimicry to trick human immune proteins, including those controlling blood coagulation and complement activation, which may drive pathology in infected patients. The researchers discovered over 150 protein mimics used by coronaviruses, including many involved in severe COVID-19 disease.
Scientists at Scripps Research Institute have uncovered a potential new strategy for treating eye diseases, including age-related macular degeneration and diabetic retinopathy. A fragment of the protein CITED2 has been shown to reduce neovascularization while preserving healthy blood vessels in mouse models.
A recent study published in JAMA Surgery found that low muscle mass and quality are linked to greater post-operative complications, hospitalization, and mortality in patients with colon cancer following colon resection surgery. The researchers followed 1,630 patients and used preoperative CT scans to analyze body composition.
A study found that consuming omega-3 fatty acids from both animal and vegetable sources strengthens the heart's membranes, improving prognosis in patients after a heart attack. High levels of these fats at admission were associated with lower risks of complications and mortality.
A study led by UC Riverside found that 55% of respondents with advanced MS experienced some form of mistreatment, including emotional abuse, financial exploitation, neglect, battering, and sexual assault. The researchers identified risk factors such as primary caregiving responsibilities and lower levels of social support.
Researchers from Sweden and Germany have found that female influence butterfly color diversity by mating with colorful males. The study suggests that Darwin's model of sexual selection explains the patterns better than Wallace's model, resolving a long-standing argument.
Research on three endangered tree species in Guam reveals that their decomposition releases nitrogen and carbon into the soil, improving forest ecosystem health. The findings highlight the importance of biodiversity and symbiotic relationships between plants and microorganisms in nutrient cycling.
Langerhans cells play a crucial role in preventing acute graft-versus-host disease by inducing the death of immune cells. Researchers at University of Tsukuba found that enhancing B7 protein expression on Langerhans cells could prevent aGVHD development, leading to improved treatments and patient quality of life.
The causal agent of cucurbit downy mildew, Pseudoperonospora cubensis, has two genetically distinct host-adapted clades, with Clade 1 infecting squash, pumpkin, and watermelon, and Clade 2 impacting cucumber and cantaloupe. Wild cucurbits serve as reservoirs for the pathogen.
The study found that titanate nanotubes (TNTs) composites exhibit superior photocatalytic performance in generating hydrogen from formic acid, outperforming titanium dioxide (TiO2). The high surface area of TNTs enables improved adsorption and interaction with platinum, leading to enhanced selectivity and efficiency.
A research team from the University of Córdoba has developed a method to calculate tree water consumption, allowing for optimized irrigation systems. This innovation enables farmers to determine if their trees are consuming water at optimal levels or experiencing stress, enabling targeted watering and maximizing production.
Scientists have discovered that ionization energy is more crucial than electron affinity in determining the efficiency of organic solar cells. This finding allows for precise design rules to be derived, aiming to maximize solar cell efficiency and potentially leading to transparent solar cells with high efficiency.
A proof-of-concept study shows cerebrospinal fluid as a liquid biopsy for precise characterization and real-time tracking of medulloblastoma. Circulating tumor DNA analysis provides genomic insights into disease evolution, enabling more effective treatment strategies.
A new 'fast' MRI test has been shown to detect breast cancers that 3-D mammograms may miss in women with dense breasts. The test, which is an abbreviated version of traditional breast MRI, detected 27 cancers per 1,000 women screened.
A recent study by The Endocrine Society found that over 80% of COVID-19 patients had vitamin D deficiency, with men having lower levels than women. Patients with low vitamin D levels also showed increased inflammatory markers.
A large observational study found that regular consumption of omega-3s EPA and ALA can decrease the risk of death three years after a STEMI, with both types providing unique protective qualities. Walnuts were also shown to have significant benefits due to their high content of alpha-linolenic acid.
Researchers stress the need for standardised methods to assess COVID-19 vaccine efficacy, highlighting challenges in determining severe disease protection and the importance of long-term follow-up. Controlled human infection studies may offer rapid assessment but predictability for older adults remains unclear.
Researchers from ETH Zurich and colleagues reconstructed the Paleocene and Eocene climates using siderite minerals, finding high humidity and heat transport. This suggests today's global warming is linked to increased moisture and heat transport in the atmosphere.
Researchers at ORNL used neutron scattering to create a three-dimensional map of the SARS-CoV-2 enzyme molecule critical to virus reproduction. The study reveals the location of every atom in the protease enzyme, enabling the design of more specific and effective drug inhibitors.
A new study from Cornell University confirms that most birds synchronize their migrations with seasonal vegetation changes, but carnivores and insect-eaters show weaker ties. Climate change threatens these patterns as vegetation cues become less reliable.
Researchers found that females can clear asymptomatic malaria infections at a faster rate than males, which could inform epidemiologists and public health strategies. The study, published in eLife, suggests biological sex-based differences play a crucial role in the human response to malaria parasites.
Scientists have identified a subgroup of stem cells that retains regenerative capacity well beyond geriatric age, suggesting new avenues for improving muscle health in elderly individuals. The discovery provides insight into the FoxO signalling pathway and its role in maintaining youthful gene expression.
Researchers have designed a cloud-based autonomous system framework utilizing the standard messaging protocol for IoT. This framework maximizes network coverage area and increases speed of communication between unmanned sensors. The team plans to add computer vision and machine learning capabilities in future developments.
A new study explores long-term if-then-scenarios to quantify the effects of Arctic summer sea-ice melting on global warming. The research reveals that complete Arctic sea-ice melt could lead to an additional 0.2°C of warming, threatening climate goals.
Acute liver failure is a rapidly progressing disease with an 80% mortality rate. Researchers identified three new subsets of liver cells that contribute to the condition's development, as well as signals from the gut microbiome. Selectively blocking these signals and depleting the microbiome led to marked improvement in liver function ...
Researchers analyzed 1,330 disease-associated genes and identified 18 features associated with pathogenic variants and 14 with benign variants. The study provides a molecular atlas of pathogenic mutations and aims to accelerate personalized drug discovery and precision medicine.
A new research effort led by the University of Tennessee Institute of Agriculture seeks to enhance communication between healthcare providers and rural patients, enabling them to discuss costs and treatment options. The project aims to improve health outcomes for those living in poverty or with limited financial resources.
A recent study published in Meteoritics & Planetary Science reveals that the 'Fireball' meteorite, recovered quickly from a frozen lake in Michigan, contains pristine extraterrestrial organic compounds. This discovery provides valuable insights into the origins of life on Earth.
Researchers found that in fights resolved by judges' decisions, winners tended to fight more vigorously than losers. Conversely, fighting skills were essential for winning in fights determined by knockout or technical knockout. The study suggests that the rate of attack is a dominant factor in determining success in combat sports.
A new study from Baylor College of Medicine found that starting genetic analysis with RNA sequencing can increase diagnostic yield by up to 17% in rare genetic diseases. This approach allows for a more comprehensive understanding of the effects of noncoding changes and enhances confidence in diagnoses.
A new report from sports cardiologists at Massachusetts General Hospital and Emory University School of Medicine offers guidance for athletes' return to play after COVID-19. For asymptomatic or mildly symptomatic athletes, detailed cardiac screening is not recommended, but those with moderate to severe symptoms should be screened for h...
A RAND Corporation study finds that health systems need better mechanisms for creating and disseminating best practices to leverage technology effectively. The study suggests that payment reform may not be sufficient to drive change and that significant investments in hardware and software are needed.
A randomized clinical trial found that electroacupuncture significantly reduced pain severity among adults with chronic low back pain. The study compared the effects of electroacupuncture to a placebo treatment, with results indicating a notable decrease in pain severity.
Researchers at the University of Virginia have discovered that cancer alters the three-dimensional structure of chromosomes to create a comfortable home for itself inside cells. This remodeling is linked to changes in gene expression and can be targeted with specific drugs, offering new approaches to cancer treatment.
The rate of fatal police shootings of unarmed Black people in the US is significantly higher than among White people. Researchers found that the total numbers of Black, Indigenous and People of Colour (BIPOC) killed in police shootings have not budged over the past 5 years.
Biologists developed fluorescent mice to visualize protein kinase A (PKA) activation in the retina. They found that light stimulation activates PKA for nearly 15 minutes in rod cells, which are essential for night vision.
Researchers found that vampire bats with illness associate less with others, spend less time near groupmates, and are less connected to healthy bats. This sickness-induced social distancing reduces transmission rates without requiring cooperation from others.
Researchers found that fluorine-18-labeled fluciclovine PET/MRI accurately identified prostate cancer lesions, suspicious lymph nodes, and detected nodal metastases not visible on conventional imaging. The technology also showed promise in evaluating response to androgen deprivation therapy.
A new study published in The Lancet Healthy Longevity suggests that older adults living in care homes have a higher risk of COVID-19 mortality compared to those living in single houses or apartment buildings. The researchers found that living arrangements, such as the type of home and neighborhood characteristics, were important factor...
A recent study provides genetic insights into Bifidobacterium infantis strains, revealing that strain EVC001 has a unique mechanism of action to optimize human milk metabolism and maximize health benefits in infants. The findings suggest that strain selection is crucial for maximizing impact on short- and long-term health outcomes.
Climate change is expected to increase cooling demand and decrease heating demand globally, while also affecting energy infrastructure efficiency and reliability. Regional differences in climate change impacts are observed, with South Asia and Latin America being the most vulnerable regions.
Researchers found that vampire bats with activated immune systems and feeling sick interacted with fewer bats, spent less time near others, and were less well-connected to the social network. This behavior helps reduce the spread of disease in highly social animals like vampire bats.
A new study from Queen Mary University of London discovers that certain small molecules in patients' blood can predict response to disease-modifying anti-rheumatic drugs (DMARDs). Up to 50% of RA patients are unresponsive to treatment, and the research provides potential solutions for predicting patient responsiveness.
Researchers determined the crystal structures of SARS-CoV-2 papain-like protease, revealing novel packing and solvent content. The findings provide valuable insight into inhibition mechanisms and may aid optimization of promising inhibitors for therapeutic development.
The sequencing of the cauliflower coral genome provides a resource for studying genetic adaptation to different environmental conditions. The analysis revealed approximately 27,500 genes, with a higher percentage of repetitive elements than closely related corals.
Research identifies commonalities in COVID-19 patients' brain activity, highlighting potential long-term effects on older males. Abnormal EEG readings suggest permanent brain damage, prompting the need for comprehensive care including brain imaging.
Researchers at TalTech have created a mechanochemical synthesis method that produces chemicals faster and with fewer environmental impacts. The technique replaces solvent-based processes, reducing toxic waste and speeding up production time.
Researchers identified VEXAS, a severe inflammatory disease caused by UBA1 gene mutations, revealing devastating consequences. The genome-first approach helped uncover the link between disparate diagnoses in patients with undiagnosed inflammatory conditions.
A new model predicts the photovoltaic industry can meet Paris Agreement targets with 70-80 terawatts of cumulative capacity from solar cells by 2055. The industry needs to increase production rate by a factor of 30 within 10 years, driven by productivity improvements and material sustainability.
Researchers found a significant disparity in fatal police shootings between Black and white individuals, with Black victims experiencing lethal encounters at a rate three times higher than their white counterparts. The study highlights the disproportionate impact of police violence on marginalized communities.
A new technology makes it possible to analyze all the tissue removed from a tumor in 3D without cutting, significantly increasing the reliability of diagnosis. This revolutionizes pathology and provides new insights into cancer development, potentially leading to improved treatment options.
Fossils found in Antarctica reveal the largest individuals of an extinct group of seabirds, which lived for up to 60 million years, dwarfing today's largest bird. The discovery sheds light on bird evolution and highlights the diversity of Antarctic birds during a warmer climate 50 million years ago.
A recent NIH study found that approximately 1 in 4 women experience high levels of depressive symptoms at some point in the three years post-childbirth. Women with underlying conditions like mood disorders and gestational diabetes are more likely to have persistent symptoms.
Researchers at Stockholm University found that Baltic Sea blue mussels are getting smaller due to changes in phytoplankton availability, which is linked to climate change. The study also discovered an increase in tiny mussels, which may compensate for the reduction in size but could lead to reduced water filtration rates.
A survey of nearly 400 cancer survivors found that 87% experienced sexual side effects, but most were not formally asked by their oncologist. Female patients were particularly unlikely to be discussed with. Researchers recommend using a standard questionnaire to initiate conversations and improve patient experience.
Researchers at USTC have designed a simple method to synthesize single crystalline wurtzite CZIS and CZGS nanobelts with exposed (0001) facets, showing excellent photocatalytic performances under visible-light irradiation. This work demonstrates the significance of surface engineering in quaternary sulfide photocatalysts.
A joint research group has developed a way to simulate the quantum physical properties of complex solid state systems using real systems of atoms. The team's approach uses mathematical and numerical methods to investigate which quantum systems are suitable for simulations, paving the way for progress in robust quantum computing.
A recent study published in Cell reveals that microglia, a type of immune cell, promote breast cancer metastasis to the brain by suppressing T-cells. The activation of VISTA checkpoint suppresses immune response, allowing cancer cells to spread and form secondary tumors.
For the first time, astronomers have surveyed over 250 million stars in the Milky Way's bulge, measuring their chemical composition and gaining new insights into the galaxy's formation. The data will help scientists understand how the Milky Way formed its central bulge and gain a better understanding of other galaxies.
A study published in STEM CELLS revealed that fibulin 5 plays a crucial role in the development of Schwann cells, which produce the myelin sheath surrounding neuronal axons. The research suggests that fibulin 5 may be used to treat Charcot-Marie-Tooth disease and other demyelinating disorders.
Researchers developed feasible approaches for durable perovskite photovoltaics by addressing internal instability, chemical degradation, and environmental factors. Compositional engineering and bonding passivation are promising methods to improve device durability.
A team led by Dr. Katherine L. Nathanson has been awarded $5.4 million to continue researching the genetic risk factors of testicular cancer, which affects men aged 15-45 in the US and Europe. The study aims to identify novel susceptibility genes and provide data for surveillance of high-risk individuals.
A randomized trial will evaluate a telehealth-delivered collaborative care model to motivate primary care patients with opioid dependence and depression to increase engagement in evidence-based treatments. The study aims to improve depression symptoms and provide pragmatic clinical approaches to address this unmet challenge.
Researchers identified a critical glycosylation step and a control protein that regulate flagellum assembly. The discovery sheds light on bacterial motility and provides insights into protein synthesis and cytoskeleton formation.
A lack of coordination among stakeholders hinders biodiversity monitoring, but integrating contributors can improve data collection. This is crucial for identifying factors leading to declines in biodiversity and creating sustainable conservation strategies.
Researchers at Washington State University have discovered mavacamten, a molecule that suppresses excessive force generated by hyper-contractile muscle cells in the human heart. The drug reduces maximal force of contraction by nearly 20-30% compared to controls, suggesting its potential as a treatment for hypertrophic cardiomyopathy.
A new study finds that Hispanic Black individuals have the worst COVID-19 outcomes, including higher hospitalization and death rates, compared to Hispanic multiracial and white individuals. The study highlights the need for more accurate demographic data collection to address these disparities.
A study aims to identify geographic and racial disparities in mammography screening rates among Black and Hispanic women. The research will inform targeted interventions to improve access to screening and reduce mortality from breast cancer.
Researchers identified a new prognostic laboratory sign for imminent postoperative thrombosis, which appears on the first postoperative day. Early detection using this sign can help prevent life-threatening thrombotic complications and improve patient outcomes.
Researchers from Binghamton University and Intel Corp. developed a tool called FakeCatcher to detect 'deepfakes,' which boast an accuracy rate above 90%. The tool analyzes the subtle differences in skin color caused by the human heartbeat, using photoplethysmography (PPG) signals.
Researchers found that aerosol microdroplets, the tiny particles lingering in the air, contain less virus than larger droplets produced during coughing or sneezing. This reduces the risk of infection in well-ventilated spaces.
Researchers from SUTD analyzed strategies employed by countries during the COVID-19 pandemic, highlighting the need for controlled movement, containment through border controls, and efficient testing to prevent transmission. The study emphasizes the importance of a collective global strategy to contain outbreaks effectively.
Research reveals basal ganglia neurons primarily use firing rate changes to control voluntary movements, with synchronized activity having a minor role in healthy conditions. Parkinson's disease symptoms may be improved by targeting abnormally increased correlated activity in the basal ganglia.
A study by researchers at UC Santa Cruz reveals the molecular mechanisms behind the 'night owl' sleep disorder, which affects one in 75 people of European descent. The genetic mutation identified alters a key component of the biological clock, causing people to stay up late and sleep in late.
A Swiss study reveals that a certain fatalistic attitude can protect individuals from negative feelings during the Covid-19 pandemic. The researchers found that in Switzerland, fatalistic attitudes were associated with less fear and fewer negative emotions compared to Israel.
A team of West Virginia University researchers are developing a protective jacket for tank cars that haul hazardous materials to prevent spills and leaks caused by accidents. The new composite material, made up of glass and polymer, improves fatigue, puncture, and fire resistance qualities.
A study revealed that individual differences can be detected in same-shaped pottery vessels, with greater variation during the formation process than in the finished form. Researchers used video footage and hand movement analysis to identify unique patterns, shedding light on how individuals adapt traditional skills.
A multidisciplinary team of specialists at Hospital for Special Surgery successfully performed microsurgery to repair damaged nerves and restore muscle strength and movement to patients with Parsonage-Turner Syndrome. The surgery allowed 11 out of 24 patients to regain function of their arm.
A group of doctors is calling on the government to divert hundreds of millions spent on failing COVID-19 national test and trace service to local primary care, NHS labs, and public health services. This would restore and rebuild needed service capacity, avoiding fragmentation created by private companies.
A recent study from UC Davis found that people's views on empathy are complicated and depend on who is receiving it. Empathizers are liked and respected only when the character they're empathizing with is also well-liked, but not when the character is disliked. This challenges the notion that empathy is always a virtue.
A new study suggests that renewable energy targets can actually exacerbate sustainability issues, such as rolling blackouts in California. The researchers argue for a more nuanced approach, considering trade-offs between different policy instruments and long-term objectives.
The FDA has awarded a grant to Critical Path Institute (C-Path) to develop real-world evidence for treatments in neonates using real-world data. This project will create a platform to standardize and integrate data from NICUs worldwide, enabling the creation of actionable reference ranges and natural history models.
Researchers studied slope failure after wildfires in Southern California's San Gabriel Mountains, finding a shift from debris flows to shallow landslides over time. The study suggests that land managers prioritize post-wildfire mitigation and planning, with debris flows being the primary concern during the next year.
Researchers have improved consistency assessment in meta-analysis by considering statistical power. This new measure can alter the interpretation of meta-analyses. Studies with high statistical power should have stronger effects on results.
Girls living in single-parent households before age two are at higher risk of starting puberty earlier than their peers. The study, published in BMC Pediatrics, found that infant attachment insecurity and socioeconomic status may contribute to this association.
Low-cost airlines proved more resilient during the pandemic due to their lower exposure to international long-haul traffic. They operated in regional markets and benefited from consolidation since 2001, increasing their market share from 5.3% to 37.3%.
Scientists developed BiteNet, a machine learning algorithm using computer vision to analyze protein structures and detect binding sites. The approach expands the array of possible pharmacological targets and improves speed and accuracy.
Researchers have discovered a general property for understanding how immune cell receptors sense and respond to microbial signals. The result led to a more effective cancer immunotherapy in mice, which could lead to more effective vaccines for existing and novel viruses.
This study identifies potential anti-COVID-19 pharmacological components of TCM's Lianhuaqingwen capsule based on human exposure and ACE2 biochromatography screening. The research demonstrates the utility of this approach for identifying pharmaceutically active components in Chinese herb medicines.
A new study examines clinical trials involving radiation therapy from 1996 to 2019 and finds that Black and Asian American patients are underrepresented, with 12% and 3% of trial participants respectively. The findings highlight the need for better inclusion of racial minorities in research studies.
A study found that antibiotic use patterns and patient transfers drive the emergence of drug-resistant microbes, highlighting the need for individualized approaches to preventing resistance. The study suggests using alternative antibiotics like piperacillin-tazobactam instead of carbapenems may be necessary.
A team of international coastal scientists disagrees with a paper predicting half the world's beaches will disappear by 2100 due to sea-level rise. They argue that beaches can migrate landward and retain their shape as long as they have space to move, but those backed by cliffs or seawalls are unlikely to survive.
Researchers from the University of Bonn and around the world propose a strategy to use soils to bind large quantities of carbon, reducing greenhouse gas emissions by a third. By increasing plant growth and crop yields through simple measures like mulching and fertilizing, farmers can effectively sequester carbon in the soil.
A study by University of Kansas researchers found that individuals with disabilities overwhelmingly believe access to healthcare is a vital human right. However, they also reported feeling marginalized and stigmatized, with many facing barriers to employment and healthcare due to restrictive policies.
The study reveals that KDM5A and PHF2 positively control the expression of pro-metastatic genes in Ewing sarcoma. These genes include L1CAM, which promotes migratory and invasive properties. The researchers identified KDM5A and PHF2 as novel disease-promoting factors and potential new targets for metastasis inhibition.
Society for Neuroscience recognizes Courtney Miller for her career-long practice of mentoring women scientists, including founding Professional Women's Nexus to provide support and connections. Miller has also achieved significant scientific success, developing treatments for drug addiction and post-traumatic stress disorder.
Researchers at Penn State have developed new methods to enhance light emission and increase signal strength in 2D materials. By altering the atomic makeup and physical shape of these materials, they created new types of materials that can attract different molecules and induce superconductivity. These advancements have significant impl...
The number of radiation therapy facilities in the US has grown by 17% over 15 years, with a disproportionate increase in urban areas. Despite this growth, 4.5% of the population lives more than 50 miles from a treatment center, highlighting access disparities.
A Yale study shows that epigenetic mechanisms play a crucial role in shaping the evolution of gene networks in yeast. The research suggests that epigenetic factors can be passed on to offspring, contributing to stable and heritable gene expression states.
Researchers discovered a two-component system in the Butters prophage that blocks entry of some phages, but not others, from attacking a strain of mycobacteria. The study advances phage therapy development and may lead to engineering phage-resistant bacteria.
A new mapping tool for analyzing tissue damage seen on MRI brain scans accurately detects early signs of cognitive decline, correlating with worsening dementia and other brain-damaging conditions. The tool offers a standardized method for calculating the volume and location of white matter lesions in the brain.