A Canadian study finds that treatment for vulnerable people with endocarditis includes in-hospital addiction support and community care, with special attention to the needs of marginalized young women. Women who inject drugs are disproportionately affected by endocarditis and have higher long-term mortality rates than men.
A four-year study aims to understand the barriers faced by female Veterans experiencing homelessness, exploring data on demographics, housing history, and services accessed. The research will inform gender-specific interventions and guidelines for policy, practice, and care.
Researchers at Lawson Health Research Institute have made a world-first discovery using advanced technology and artificial intelligence (AI) to accurately diagnose rare diseases and prenatal exposure-related birth abnormalities. They used EpiSign technology, which measures a patient's epigenome, to identify patients affected by recurre...
A large international study of 1,042 living kidney donors found no significant differences in health indicators compared to non-donors seven years after donation. The study also provides insights into recovery time from living kidney donation, suggesting a longer recovery period than previously thought.
A recent study found that alterations in the human microbiome, including those in the gut, urinary, and salivary tracts, are linked to kidney stone formation. The research team discovered changes in these microbiomes were common among patients with kidney stones.
Lawson Health Research Institute's AI-led technology can diagnose rare genetic diseases with a blood test, taking its development global thanks to a $7.55 million grant. The technology has the potential to revolutionize healthcare by providing an accurate and non-invasive diagnostic tool for these complex diseases.
Researchers at Lawson Health Research Institute have discovered unique patterns of blood plasma proteins in patients with long COVID, which could lead to new diagnostic tests and treatment therapies. The study found prolonged inflammation associated with changes in immune cells and blood vessels, affecting organs like the brain and heart.
A phase I trial found that combining fecal transplants with immunotherapy is safe and shows promise in improving clinical responses in 65% of patients. The study used healthy donor microbiome to enhance immune system attack on cancer, offering a new paradigm shift in melanoma treatment.
A team at Lawson Health Research Institute discovered unique patterns of blood plasma proteins in critically ill COVID-19 patients, which may aid in developing targeted therapies. By analyzing over 1,000 proteins, researchers found changes in immunosuppression pathways and identified potential biomarkers for the disease.
Researchers found that vaping can increase surface tension in lung surfactant, reducing its ability to support proper lung functioning. The study suggests a link between vaping and increased susceptibility to lung injuries, including those caused by respiratory viruses like COVID-19.
A new study has found that testing for cyclin-dependent kinase inhibitor protein (p16) in biopsy tissue can help more accurately identify IPF. High expression of p16 is associated with worse outcomes and reduced survival, emphasizing the need for early treatment.
A new form of expanded dialysis has been found to improve the quality of life for patients with chronic kidney disease, including increased energy and better sleep. The treatment, which removes a broader range of toxins from the body, was tested in a clinical trial and shown to reduce inflammation and improve overall well-being.
A recent study from Lawson Health Research Institute found that frequent use of Paravertebral blocks increases health care utilization, including physician visits and other injection procedures. The study also showed no overall change in opioid dosage after the initiation of PVB treatment.
A population-based study found that children born in Sarnia, Ontario have a higher risk of developing asthma compared to neighboring cities. Air pollution exposure in the first year of life was associated with the development of asthma in children.
A simple device improved care after kidney transplantation by reducing swelling, hospital stays, and surgical site infections. Patients experienced a 31% reduction in swelling and a 60% decrease in wound infection rates.
Researchers discovered specific metabolites that can distinguish COVID-19 patients from healthy participants and predict disease severity. Dietary supplements targeting these metabolites may also boost biochemical pathways, leading to improved health outcomes.
A new study suggests that the gut microbiome plays a role in how prostate cancer patients respond to oral therapies like abiraterone acetate. The research found that bacteria in the gut metabolize the drug, leading to an increase in beneficial organisms with anti-cancer properties.
Researchers discovered unique bacterial profiles associated with each patient's medical condition, suggesting a personalized approach to care and antibiotic treatment. The study challenged long-held beliefs that the urinary tract is sterile.
Researchers have identified six molecules that can be used as biomarkers to predict how severely ill a patient with COVID-19 will become. Additionally, they discovered a new mechanism causing life-threatening blood clots in COVID-19 patients and potential ways to treat them.
A team from Lawson Health Research Institute is conducting a multi-centre clinical trial to study the use of inhaled sedatives as an alternative to intravenous sedatives for COVID-19 patients requiring ventilation. The trial aims to improve patient outcomes and address global shortages of IV sedatives.
A study has identified six molecules that could be used as therapeutic targets to treat COVID-19. The research team found that these molecules were uniquely elevated in the blood of critically ill patients, and were able to predict the presence of COVID-19 with high accuracy using artificial intelligence.
A new study found that fecal transplants can reduce intestinal permeability in patients with non-alcoholic fatty liver disease (NAFLD), a condition associated with metabolic syndrome and autoimmune diseases. The treatment shows promise for improving gut health and preventing further inflammation.
Researchers are conducting three studies to investigate important COVID-19 questions, including a trial of annexin A5 as a potential therapy for critically ill patients. A novel blood test for COVID-19 is also being developed using epitopes.