Researchers at DZNE's Dresden site develop i3D-Markers, a cutting-edge technology platform that uses high-density microelectrode arrays and 3-dimensional neuronal networks to predict the reaction of neurons to compounds. This platform aims to optimize drug candidate selection and accelerate brain disease development.
EarthLab aims to simulate physical climate, environmental, and ecological systems for better predicting natural disasters and understanding Earth's spheres. The facility will enable researchers to predict Earth systems on a vast time and spatial scale.
A research team led by ECU's Natasha Bell has received a $1.2 million grant to overcome barriers to growth in North Carolina's aquaculture industry and strengthen wastewater infrastructure. The project aims to develop new ecological engineering treatment technologies, including hybrid constructed wetlands and novel 3D-printed materials.
A study published in Economic Inquiry examined data from 133 countries from 1950-2014, finding that reduced fiscal space in high-income countries after the 2007-2009 global financial crisis led to procyclical policy actions. This resulted in prolonged economic downturns and aggravated business cycle fluctuations.
A new study reveals that tropical rainfall clusters in the western Pacific contribute to East Antarctic summer cooling. The Madden-Julian Oscillation (MJO) plays a key role in this phenomenon, with MJO-related rainfall and pressure changes favoring cooling of East Antarctica.
A new study from Stanford University School of Medicine found that hospitalizations to treat pediatric gun injuries are expensive, with a total of about $109 million spent each year. The cost of hospitalizations rose over time, with more than half paid by Medicaid and uninsured patients accounting for 11% of all hospitalizations.
Researchers from Bentley University analyzed reader comments on two partisan news sites after a challenging news event, revealing obstacles to sense-making and breakdowns in deliberation. The study adds to the understanding of political discourse and polarization, highlighting the need for solutions to combat misinformation.
Researchers used functional MRI to understand how the brain's reward areas react to e-cigarette aerosols with and without flavor. For smokers, unflavored e-cigarettes may mimic the typical smoking experience more than flavored e-cigarettes.
A 29-year-old woman was hospitalized with sepsis 14 months after a dermal filler injection, revealing rare bacterial causes and increasing awareness of the need for cosmetic patients and healthcare professionals.
A new University of Kentucky study will examine the effects of flavored tobacco product restrictions on health disparities among communities of color, low-income populations, and youth. The research aims to inform community leaders about how policies can help eliminate health inequities.
A new AI model can quantify individual deviations from typical aging trajectories in patients with mild cognitive impairment, indicating potential for earlier diagnosis and treatment. The study found that the model's predicted age difference was significantly associated with cognitive decline and progression to Alzheimer's disease.
Researchers found that early British Antarctic expeditions fed their dogs inadequate amounts of Spratt's dog cakes, leading to desperation and hunger among the canine team members. The study suggests that the dogs required significantly more energy-rich food to sustain their high-energy activities.
Researchers discovered that SARS-CoV-2 produces microRNAs affecting individuals' respiratory systems and immune responses. Understanding these impacts may provide new insights into COVID-19 pathogenesis and treatment.
West Virginia University is part of a team awarded $17 million from the National Science Foundation to renew the NANOGrav Physics Frontiers Center. The center aims to detect gravitational waves using pulsar timing arrays and will advance research in fundamental physics.
A study examined changes in physician work hours and patterns during the COVID-19 pandemic, finding significant shifts in work activities. The researchers discovered that physicians reduced their work hours, with a notable increase in work-from-home activities.
A new study published in the Journal of the Association for Consumer Research posits that increased accessibility to anthropomorphized luck can lead consumers to pursue higher-risk financial behavior. The authors suggest that preferences for riskier options are driven by shared risk perceptions that may engender feelings of security.
A new recycling robot will use AI and computer vision to sort recyclable waste, separating soft plastics from other materials. The system aims to drastically increase soft plastic recycling in Australia, diverting millions of tonnes of waste from landfills.
Researchers discovered that pancreatic cancer cells use a backup protein complex to survive when KRAS is blocked, allowing them to continue growing and dividing. This finding highlights the need for drugs that can target multiple molecules in cancer cells to improve treatment outcomes.
Researchers analyzed over 900 patents to identify key technological trends in the New Space economy. The study found that data is the most valuable asset in this ecosystem, with 62% of patents related to data products and services. Emerging topics include active constellation management and new satellite systems design.
The Prevent COVID U study has expanded to enroll young adults ages 18-29, including those who choose not to receive a vaccine. The trial aims to test the effectiveness of the Moderna COVID-19 Vaccine in preventing infection and transmission of SARS-CoV-2.
Researchers at UNC-Chapel Hill developed a universal vaccine that protects against multiple coronaviruses, including COVID-19 and SARS. The hybrid vaccine effectively generated neutralizing antibodies against various spike proteins, preventing infection and lung damage in mice.
Researchers at SUTD use nanoscale 3D printing to create ultra-realistic 3D images with a maximum pixel resolution of 25,400 dpi. The high-resolution light field prints display autostereoscopic images that change appearance when viewed from varying angles.
Researchers at Duke University developed acoustoelectronic nanotweezers that control nanoparticles using sound-induced electric fields. This label-free, dynamically controllable method can be applied to various technologies, including biomedicine and condensed matter physics.
A new study found that political partisanship was the strongest predictor of whether someone would wear a mask or practice social distancing. Those who identified as liberal or moderate were more likely to wear masks and socially distanced, even when they believed their risk was minimal.
Researchers discover specially adapted microorganisms that can use methane as an energy source in the hot seafloor sediments of Guaymas Basin. These microbes play a crucial role in carbon cycling and support a diverse food web, with implications for the deep-sea ecosystem.
A new study reveals that a hormone in fat cells inside bone marrow helps regulate bone and fat production. The findings suggest potential new approaches to treating conditions like osteoporosis.
A new device at the University of Exeter allows for more precise sorting and analysis of individual human cells based on their response to stimuli. This innovation has the potential to improve personalized medicine by detecting which drugs are likely to work for specific patients, reducing unnecessary side effects.
Scientists at the University of Cincinnati have developed a blueprint for the protein anti-Müllerian hormone (AMH), which plays a crucial role in reproductive organ development. Understanding how AMH interacts with its signaling receptor may lead to novel treatments for infertility, polycystic ovary syndrome (PCOS), and even feral cat ...
A new study reveals that common OTC drugs for sore throat are more harm than good, causing inflammation and damage to upper respiratory cells. Biovanta, a naturally derived drug, has been shown to reduce inflammation and treat respiratory inflammation effectively.
Researchers clarify the role of SMN complexes in splicing and Cajal body formation, which is crucial for protein translation. The study reveals kinases play a key role in regulating these processes, potentially leading to new therapies for spinal muscular atrophy.
A new study predicts severe drying of the Amazon forest, threatening its viability and biodiversity. The eastern part of the Amazon is expected to face extreme drought by the end of the century, with reduced rainfall comparable to major droughts in 2005 and 2010.
The study found ADCs made with cleavable linkers can decrease small-cell lung cancer tumor size in PDX mouse models, showing promise for improved efficacy. The 'bystander effect' kills nearby nontargeted cancer cells often found near malignant tumors.
Researchers found that fortified tea with folate and vitamin B12 can increase serum levels of these essential nutrients in Indian women. The study showed significant average increases in serum folate and vitamin B12 levels, as well as improved haemoglobin levels, after 2 months of daily consumption.
Researchers found no association in SARS-CoV-2 positivity rates between healthcare workers wearing respirator masks and those wearing medical masks. The study suggests that mask utilization is not a significant factor in preventing SARS-CoV-2 transmission among healthcare workers.
A new study from Aarhus University found that over 80% of participants have more than three genetic variants affecting medicinal product metabolism, increasing the risk of reduced effect or side effects. Genetic tests can provide personalized treatment plans by analyzing multiple genes and variants.
Researchers at the University of Waterloo discovered that nanoscale electrocatalysts degrade and lose effectiveness over time due to atomic rearrangement. The study identifies two key reasons for this degradation: surface attachment of small molecules and electromigration.
Researchers found over 30 species of plants along the banks of Tikal's reservoirs, including trees like ramón and cabbage bark. The study suggests that the Maya protected these areas as sacred groves to provide medicinal or edible plants and fruits.
A new study by King's College London suggests that anxiety experienced by mothers during pregnancy is not passed on to their children. However, exposure to an anxious parent after birth may have a modest impact on the development of emotional problems in children.
A University of California, Riverside study found Salton Sea aerosol triggers nonallergic inflammation genes and promotes lung inflammation in mice. The researchers also observed a distinct inflammatory response in the lungs compared to exposure to aerosolized fungal allergen.
Researchers at Oregon State University have identified a new genus and species of fungal parasite in an ancient ant fossil, shedding light on the origins of this complex relationship. The discovery, published in Fungal Biology, reveals that the fungus can manipulate its host ant's behavior to facilitate its own reproduction.
A University of Georgia study reveals the complex web of human conflicts hindering endangered species conservation in South Africa. The oribi's fate is entwined with private landownership, political corruption, and racial tensions.
Researchers have identified an olfactory receptor that selectively recognizes pyrazines, a type of volatile substance found in food and contributing to animal communication. This discovery could lead to the development of biobased artificial noses for monitoring sensory quality and authenticity of food.
Climate change is expected to suppress the growth of Florida's coral reefs due to their inability to migrate north. The warming seas and increasing frequency of water-cooling cold snaps will make it difficult for corals to adapt and survive, leading to further decline and potentially extinction.
Researchers at NTHU and IU developed a novel four-component coupling strategy for olefins, resulting in asymmetric radical trifluoromethylation. The reaction utilizes chiral VO species as catalysts under aerobic conditions, offering high diastereo-/enantio-controls and potential applications for biomedical compounds.
A team of researchers from the University of Queensland has discovered a venomous caterpillar that produces peptides with high potency against nematode parasites and disease-causing pathogens. The study also unlocks a source of bioactive peptides with potential uses in medicine, biotechnology, and scientific tools.
The Universidad Carlos III de Madrid has patented a multicore fibre optic monitoring system for 5G networks, optimizing energy consumption while preserving data transmission capacity. The system can monitor temperature changes, energy distribution, and communication channel state using a single optical signal.
A study of over 11,000 individuals found that actively addressing inequalities fosters social change when both disadvantaged and advantaged groups feel heard and accepted. Empowerment through active listening and acknowledgment of injustices are key factors in promoting social justice.
Vaccine developers suggest that documented side effects are a byproduct of an effective immune response. The authors argue that fatigue and headache after vaccination should be viewed positively as a necessary step towards herd immunity.
A study by Nagoya University researchers reveals that cohesin's ring needs to open for certain processes, like DNA replication and chromosome segregation. This opening facilitates the progressive replication of the DNA double helix and allows DNA looping, crucial for regulating gene expression.
Scientists have found a way to filter wastewater through the roots of willow trees, treating over 30 million litres of primary wastewater per hectare annually. The process produces renewable lignocellulosic biofuels and 'green' chemicals with antioxidant, anticancer, anti-inflammatory and anti-microbial properties.
NCRI has created an Early Career Researcher Forum to build collaborative networks, enhance skills, and support career development among early career researchers in cancer. The forum aims to accelerate cancer research by providing opportunities for peer support, mutual learning, and collaboration.
A recent study found that statin use among patients with heart failure is associated with a 16% lower risk of developing cancer and a 26% reduced risk of dying from cancer over an average of four years. The longer patients remained on statins, the greater the reduction in their cancer risk.
Researchers at Linköping University discovered that XPS can give misleading analysis results due to an erroneous assumption during calibration. This error has led to the publication of interpretations of data in conflict with basic physics, raising concerns about research credibility.
A recent study published in The Journal of Nutrition found that animal-based protein food sources elicited greater anabolic responses and increased whole-body net protein balance compared to plant-based protein food sources. This suggests that 'ounce equivalents' of protein food sources are not metabolically equivalent, and animal prot...
A study published in the Journal of Investigative Dermatology found that a Western diet rich in sugar and fat disrupts gut microorganisms, leading to psoriasis flares. Switching to a balanced diet restores gut health and suppresses skin inflammation, offering a potential solution for managing the condition.
Researchers discovered a brain mechanism that regulates whole-body glucose balance without altering body weight, indicating a promising therapeutic target for type 2 diabetes. By modulating this mechanism, it may be possible to regulate blood sugar levels in obese individuals with diabetes without requiring weight loss.
Researchers developed a synthetic tree to enhance solar steam generation, which can turn solar energy into heat to harvest drinking water. The tree overcomes the limit in capillary force by mimicking transpiration, allowing for increased efficiency and scalability.
Researchers found that listening to self-selected motivational music improved interval running capacity and 5km time-trial performances in mentally fatigued fitness enthusiasts. The positive effects may be due to altered perception of effort when listening to tunes.
A new class of drugs inhibiting the SOX 11 oncogene has been discovered by researchers at Mount Sinai, showing promising results in treating mantle cell lymphoma. The discovery could lead to new therapies for a disease resistant to existing treatments.
A study found that initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids in children with Multisystem inflammatory syndrome in children (MIS-C) was associated with a lower risk of cardiovascular dysfunction. This is compared to IVIG alone, where left ventricular dysfunction occurred in 17% of patients.