Researchers developed an AI algorithm that can identify patients at high risk of intentional self-harm using unstructured clinical notes. The model achieved an accuracy of 98.5% in identifying current at-risk patients, but struggled with predicting future self-harm due to the presence of irrelevant information.
Researchers identified genetic markers outside of FLT3-ITD mutations that affect midostaurin response in leukemia patients. These findings suggest therapeutic benefits of midostaurin in patients with specific expression profiles, and may lead to more effective combination therapies.
A study published in PLOS ONE found that about 1/3 of young women in 43 LMIC have lost at least one sibling before the age of 25. Sibling loss was relatively more common in countries affected by conflict and war, while bereaved respondents in many studied countries still had a comparable number of remaining living siblings.
Researchers at Massachusetts General Hospital have developed a non-invasive liquid biopsy test that can detect genetic mutations in brain tumor patients. The test, which improved detection sensitivity by tenfold, has the potential to revolutionize glioma diagnosis and monitoring.
Researchers sequenced and analyzed coral genomes, discovering genes that may help corals adapt to ocean warming. The study found that Acropora corals diversified when the world's oceans were warmer, suggesting they could handle temperature changes.
A five-year study aims to explain the microbial, clinical, and antimicrobial resistance factors of three major multidrug-resistant pathogens. The research will utilize state-of-the-art analysis of genomes and microbiome analyses using stool samples and blood samples.
Researchers from Pohang University of Science & Technology (POSTECH) used artificial intelligence to create novel materials for memory devices. By controlling atomic structures, they discovered a unique ferroelectricity pattern, leading to the synthesis of a new material with unprecedented properties.
Researchers discovered a new protein called cryptochrome that repairs DNA damage caused by ultraviolet radiation, a function previously attributed to photolysis in cells. This breakthrough highlights how proteins can evolve and acquire new functions over time.
Researchers found that chronic jet lag alters the microenvironment surrounding tumor cells, making it favorable for tumor growth, while hindering the body's natural immune defenses. This study adds to the growing scientific field of circadian disruption on health and wellbeing.
Researchers from Tokyo University of Science design a new quantum circuit that calculates the fast Fourier transform, a key algorithm in engineering. The QFFT circuit exploits superposition of states to greatly increase computational speed and is more versatile than traditional QFT.
The Cardiff model, a data-sharing approach between hospitals and police, is lowering violent injury rates worldwide. Cities adopting this model are seeing significant drops in violence, with the World Health Organization endorsing its impact.
Scientists use a custom robot to survey how mutations in regulatory regions of the genome affect animal development, revealing that most mutations alter gene expression in some way. The study finds that regulatory regions encode valuable information densely and that single mutations can have several different effects.
A new study by the University of Sussex Business School reveals that countries signing up to the Extractive Industries Transparency Initiative (EITI) have seen significant reductions in carbon emissions, with an average decrease of 13% between 2000 and 2014. In contrast, the world average carbon footprint per capita grew by 23% over th...
A new study confirms that plastic pollution is a significant threat to seabirds in the South Pacific Ocean, with globally distributed impacts. The research found that seabirds ingest plastics from distant areas, highlighting the need for urgent solutions to this global problem.
Researchers at MIT have developed a more practical and efficient solar-powered system that can extract drinkable water from dry air, doubling its output compared to an earlier version. The new system uses a readily available adsorbent material, increasing scalability and feasibility for remote regions with limited access to water.
Researchers at University of South Florida have discovered a key molecule involved in regulating flexibility in animal stress responses. The study provides a novel perspective on how vertebrates cope with environmental stressors and highlights the importance of understanding stress response flexibility for both human and animal health.
Researchers at TUM have developed human intestinal organoids as a model for studying nutrient and drug transport in the intestines. These miniature intestines can accurately reflect physiological processes inside humans, paving the way for medical and pharmaceutical applications such as drug screening.
Scientists have identified the crucial role of RAD51 protein in recruiting TERRA molecules to telomeres, which helps prevent accidental loss or shortening of DNA. This mechanism is essential for maintaining healthy telomeres and preventing premature aging and age-related diseases.
A new study by researchers at the University of Eastern Finland provides novel insight into the previously unknown effects of factors regulating blood vessel formation. Bone morphogenetic factor 6, BMP6, is shown to regulate blood vessel formation via vascular endothelial growth factor receptor 2 (VEGFR2) and Hippo signalling pathway.
A study by Valeria Ramírez-Castañeda found that over 90% of articles published by Colombian researchers are in English, creating financial burdens. Many respondents reported being unable to attend scientific conferences or publish due to language barriers, disproportionately affecting those from poor backgrounds.
Researchers developed biocompatible tissue grafts that repaired both bone and cartilage in the temporomandibular joint (TMJ) of pigs. The study showed promising results with intact grafts after 6 months, outperforming existing designs.
A study by the University of Eastern Finland found that online horse race bettors tend to stay away from betting for a longer time after a losing day. The study analyzed data from over 9,000 individuals in Finland and found no significant differences in behavior between men and women.
A new species of small pterosaur with a long, skinny beak like that of a Kiwi has been discovered. The fossilized piece of beak revealed an incredible network of internal canals for nerves that helped detect prey underground.
The study reveals that efavirenz alters the gene expression of important factors essential for genomic stability, particularly down-regulating S-phase and DNA replication genes. This suggests that efavirenz may be used in synergy with chemo/radiotherapy to treat lung cancer.
A severe drought in East China from August to October 2019 was exacerbated by warm central equatorial Pacific sea surface temperatures and global warming. The study suggests that while natural climate variability played a role, human-induced climate change amplified the droughts likelihood.
Researchers create an artificial C-to-U conversion system using APOBEC1, allowing for the restoration of mutated genes and potentially treating genetic disorders. The system was tested on blue fluorescent protein (BFP) RNA with a 199T>C mutation, showing high editing efficiency.
Researchers studied aortic dissections in pregnant women, finding 19% associated with pregnancy and increased risk of Type A dissections. The study highlights the importance of careful monitoring of cardiac conditions during pregnancy.
Two studies suggest individuals with blood type O may have a lower risk of COVID-19 infection and reduced likelihood of severe outcomes. In contrast, those with blood groups A and AB may be more likely to experience severe clinical outcomes and organ complications.
Researchers at Flinders University have developed a novel protocol to detect lipid production in microalgae, enabling the mass production of omega-3 fatty acids and other healthy compounds. The technique improves on traditional fluorescent probes, allowing for easy and rapid evaluation of lipid conditions within microalgae.
Only 7% of US school districts in poorer, ethnic minority populations intend to reopen fully this academic year. The study highlights the disproportionate impact of the pandemic on people of color and their increased likelihood of being frontline workers, leading to a lack of trust in government responses.
An international group of scientists raises concerns about a recent publication evaluating an AI system for breast cancer screening, citing restrictive data access and lack of transparency. The authors argue that protecting patient privacy should not hinder the broader research community from contributing to methodology and correcting ...
A new US study found that hospital-based waterbirths have no higher risk of NICU admission compared to control group births. Waterbirth was also associated with reduced perineal lacerations and improved patient satisfaction.
A resiliency program for brain injury survivors and their caregivers has shown clinically significant improvement in emotional distress. The program, Recovering Together, achieved measurable reductions in depression, anxiety, and post-traumatic stress among individuals with acute neurologic illness and their caregivers.
A new study found that 40% of tenant households in Australia struggled to afford essentials like bills, clothing, and food after paying rent, due to reduced incomes during the pandemic. Many renters also reported negative effects on their mental health, with around half indicating they were affected.
Researchers found that DNA enhancers contain more information than previously thought, leading to changes in gene expression patterns. This discovery provides insights into how evolution takes place and challenges previous assumptions about enhancer function.
A recent study published in the European Heart Journal - Acute Cardiovascular Care reveals that one in five high-risk patients undergoing major non-cardiac surgery will develop one or more heart complications within a year. The study found that patients are at risk for a longer period than previously thought and that measuring troponin...
A survey of New York City residents found that many are hopeful for the city's recovery from the pandemic, but concerned about a potential COVID-19 resurgence and its disproportionate impact on communities of color. The survey also revealed significant economic disparities, with food insecurity affecting nearly 40% of households.
Scientists successfully printed wearable circuits directly onto human skin using a room-temperature sintering method, enabling seamless integration with the body. The novel approach produced reliable and comparable signal quality to conventional commercial devices for health monitoring applications.
A MU researcher developed a world's first health care transition readiness assessment for adolescents with autism, identifying skills needed for transition from pediatric care to adult care. The study found that young adults with autism can benefit from better understanding medication management, insurance policies and health care fina...
The University of Texas at El Paso has received a $1.35 million NIH Science Education Partnership Award to attract high school students from economically disadvantaged communities to pursue undergraduate degrees in engineering and biomedical sciences. The project, Project ACE, will provide research-focused curriculum, mentors, and oppo...
A new study suggests that nerves responsible for sensing touch and pain may contribute to the development of autism. The exploratory study found that people with autism have differences in their sensory perception, including reduced nerve fiber density and altered responses to heat and touch.
A satellite analysis reveals over 1.8 billion trees cover 2.5 times France's surface area, making a significant contribution to biodiversity, carbon storage, and dry tropical ecosystems.
A recent study by USDA Forest Service researchers found that thinning and prescribed fire can significantly reduce tree mortality and increase tree growth. The study compared two thinning methods and found both were effective in reducing tree deaths and promoting healthy forests.
Researchers identified 28 new genes associated with developmental disorders, including 500 families, using the largest genetic resource available. The study estimates that another 1,000 genes linked to these conditions remain undiscovered.
Physicists from UNLV and University of Rochester make breakthrough in quest for room temperature superconductor, enabling infinite and perfect electrical flow with no loss of power. The discovery has implications for energy storage and transmission, and could revolutionize devices, transportation, and society.
If SARS-CoV-2 becomes endemic, its pattern of transmission will depend on factors like vaccine availability and social factors. Greater monitoring of interactions with other respiratory viruses is needed to mitigate potential outbreaks.
Researchers have discovered evidence of Byzantine and Early Islamic resource management practices through micro-geoarchaeological investigations of trash mounds in the Negev region of Israel. The findings provide insights into agricultural shifts during the Roman Imperial Period and Late Antiquity.
Scientists from around the world collaborated to develop digital tools to track, understand and predict COVID-19 effects. The Digital Sprint produced innovative solutions for Air Quality, Recovery, Ecosystem Services and Visualising Risk.
The study found that only four protected areas in Côte d'Ivoire still host forest elephants, with low density. Human population size, habitat degradation, and cocoa plantation conversion significantly impact elephant presence.
A new digital intervention developed by pharmacists has significantly reduced hazardous prescribing rates in general practice, with a 43% reduction reported after 12 months. The SMASH intervention uses real-time data to identify patients at risk and provides near-constant feedback to prescribers.
The study found that modern humans settled along the Mediterranean coast before expanding into the Sinai desert and eastern Jordanian Rift Valley. Favorable environmental conditions, including a freshwater lake known as Lake Lisan, enabled human settlement and spread throughout the region.
A recent study found that the COVID-19 pandemic led to a significant decrease in global carbon dioxide emissions, with a total drop of 1551 million tonnes. The pandemic resulted in a 16.9% decline in emissions in April, largely due to lockdown measures and reduced transportation sector activity.
The COMBINE (OCT-FFR) trial found that the presence of TCFA is a strong predictor of future MACE, despite lack of ischemia. Combining FFR and OCT can improve accuracy of high-risk lesion identification in patients with diabetes.
The project aims to employ people formerly injected drugs and provide a robust recovery ecosystem by aiding recovery and physical health, with state-certified peer navigator/recovery coaches at the forefront. The goal is to create a comprehensive and sustainable approach to support those in recovery.
Research by University of Bergen scientists has found that patients with critical COVID-19 often have antibodies blocking interferons, a crucial part of the body's defense system. This finding may explain gender differences in severe COVID-19 cases and offer potential treatment options.
A NYU health economist expects a Biden administration to restore the US Affordable Care Act's original functionality and implement a more effective pandemic response. A Public Health Job Corps could be established to conduct contact tracing and improve global preparedness against future pandemics.
The study found that transportation emissions decreased by 19.2% and aviation pollution plummeted by 37.4% due to reduced human mobility. The largest decline was seen in the US, with a 13% drop in CO2 emissions.
Researchers at University of Helsinki identified mechanism behind bone marrow failure in Fanconi anaemia by finding MYC gene overexpression. This led to stem cell detachment from the bone marrow and development of bone marrow failure.
The four-year study aims to determine how environmental changes modify nutrient pollution in the Tar-Pamlico River Basin, examining local policies' influence on water quality. The research team will collect soil samples to measure the effect of increasing saltwater concentrations on microbial processing of nitrogen.
Researchers have found that a virus-mimicking drug can make certain stealthy melanoma tumors visible to the immune system, allowing for better targeting by immunotherapy. The findings open up new possibilities for personalized therapies in hard-to-treat cancers.
Researchers found that human activities since 1940 have increased the risk of acidification in the Murray estuary during droughts. The study uses historical data and geological records to understand the estuary's formation and evolution. Improved management of the Murray-Darling system is crucial for water resource sustainability.
Climate scientists extend Atlantic sea-surface temperature record to 2900 years, finding the past decade as the warmest interval. The study uses ancient lake sediments to reconstruct temperatures and atmospheric pressure over time.
A review of 39 randomized clinical trials found that combining therapy with medication is more effective in preventing illness recurrence in people with bipolar disorder. Psychoeducation and group therapy were particularly helpful in reducing symptoms and improving outcomes.
A study found that people who support immigration are ready to adopt empathy and perspective taking, while those opposed feel more competition. The research suggests that explicit instructions for empathy may not work on people of different political opinions.
Rapid population growth in rural gateway communities poses significant planning challenges due to increased housing costs, traffic congestion, and environmental degradation. The GNAR Initiative aims to help local officials prepare for these pressures through a webinar series on amenity migration.
A new study by Anglia Ruskin University found that both traditional and biodegradable glitters can harm freshwater habitats. The presence of glitter reduced root length and chlorophyll levels in water, indicating a negative impact on phytoplankton and aquatic ecosystems.
UC Santa Barbara researchers modeled the spread of SARS-CoV-2 in different temperatures and relative humidities. They found that respiratory droplets can travel longer distances than recommended social distancing guidelines, especially in cooler environments. The study suggests aerosol transmission may be more significant in summer, re...
A new study by the University of California - Davis Health found that the COVID-19 pandemic led to an estimated 110,000 firearm purchases in California and increased individuals' worries about violence. Respondents who bought firearms mainly did so for self-protection, citing concerns over lawlessness and government actions.
Researchers discovered a blood profile that predicts patients at greatest risk of life-threatening immune system overreaction in COVID-19. Combining this cytokine test with clinical assessment could help doctors identify and treat those most at risk.
An international study found that England, Wales and Scotland had among the highest rate of deaths from all causes, including COVID-19. The research estimated a total death toll of 206,000 more people in these countries than expected between mid-February and end of May.
The Hittite cuneiform scripts will be made available online, providing access to 30,000 clay tablets and fragments written in the Hittite language. This digital platform aims to boost Hittitology research worldwide.
A study found that people with severe apathy are 80% more likely to develop dementia than those with low apathy. Greater apathy was also associated with worse cognitive scores, highlighting its potential as an early sign of the disease.
A retrospective study of 52 COVID-19 patients found that asymptomatic individuals had higher levels of lymphocytes, cleared viral particles faster, and had lower risks of long-term complications. The study suggests an important role for lymphocytes in controlling virus shedding.
Researchers used leaf reflectance spectra to illuminate the evolution of seed plants over 350 million years, revealing phylogenetic diversity and constraints on spectral variation. The study's findings have significant implications for monitoring plant biodiversity and ecosystem function.
Studies have revealed that the journey of a nascent protein to become a mature cell surface receptor involves multiple steps and complex interactions with proteins such as C1orf27, HCR1, and GGA3. Understanding these mechanisms is crucial for optimizing hormone and drug use targeting GPCRs.
A recent study on the 2011 Norwegian terrorist attacks found that family members experienced three distinct grief trajectories: moderate, chronic, and those with little to no recovery. High levels of grief were common among participants, with intrusive thoughts contributing to delayed recovery.
A recent study aims to elucidate the link between B-type natriuretic peptide (BNP) and severe sepsis. Researchers found that BNP is increased in heart cells under stress, leading to lower cardiac output and promoting hypotension in septic patients.
A nearly 1.5-kilometer-long trackway of early-human footprints has been discovered at White Sands National Park, showing a woman or adolescent male carrying a toddler in their arms. The tracks, dating back over 11,500 years, suggest a perilous journey through mud and animal habitats.
Researchers found that AI techniques are being used to process information about brain structure and connectivity, assess surgical candidacy, and predict disease trajectory. However, they emphasize the need for explainable algorithms to ensure trust in algorithmic prescriptions or diagnoses.
A new study by Mount Sinai researchers found that a person's risk of uncontrolled chronic disease increases after moving to a place where the condition is more common. The study analyzed millions of adults who moved to new neighborhoods, counties, and states, tracing how their health changed after the move.
Researchers have discovered a new way to observe color through the scattering process, which combines with optical interference to create bright colors. The findings, published in Advanced Optical Materials, could have practical applications in sensing technology and security devices.
Sarah-Maria Fendt and Markus Ralser receive the EMBO Gold Medal for their pioneering work in understanding metabolic changes during cancer proliferation and metastasis formation. Their discoveries have the potential to develop more effective cancer therapies.
A new study from UNC-Chapel Hill reveals that the swine acute diarrhea syndrome coronavirus (SADS-CoV) strain has the potential to spread to humans. The virus efficiently replicates in human airway and intestinal cells, raising concerns about its threat to public health.
A study by UNLV social media expert Natalie Pennington and Iowa State professor Kelly Winfrey examines what motivates people to engage in politics online. The research suggests that interpersonal relationships outweigh political motivations for some individuals, but high-influence goals drive others to share their views.
The 'nap' protein complex, essential for M. pneumoniae's attachment, movement, and transformation, has been clarified at the atomic level. The study reveals that P40/P90 proteins bind to sialic acid substance on cell surfaces, contrary to popular belief.
The study found that lipid-rich plaques detected by NIRS imaging are associated with adverse outcomes and can be used as a prognostic index for vulnerable plaques. High-risk plaques were identified in patients with recent myocardial infarction, and their presence was linked to increased risk of future cardiac events.
Researchers at the University of Helsinki found that thawing permafrost releases volatile organic compounds, including monoterpenes and diterpenes, which can be highly reactive and contribute to cloud formation. The study's findings introduce new uncertainties to climate change modeling.
A study found that urban daycare children developed more diverse microbiomes and signs of a better-regulated immune system after playing in renovated yards with natural forest floor. The intervention improved immune regulation and health-associated commensal microbiota among 3-5 year olds.
A new machine learning model has been developed to help characterize compounds in the development of new drugs. The model uses tandem mass spectrometry and is based on a small amount of positive and negative training data, making it useful for automating characterization of compounds by chemists.
Rochester researchers have created a new type of superconducting material that can conduct electricity without resistance at room temperature. This discovery opens the door to potential applications in power grids, levitated trains, medical imaging, and electronic devices.
The Membrane Solvent Extraction (MSX) process developed by Oak Ridge National Laboratory allows for the recovery of highly pure cobalt, nickel, lithium, and manganese from spent lithium-ion batteries. This technology contributes to a circular economy by recycling end-of-life products without generating hazardous waste.
International scientists challenge their colleagues to make Artificial Intelligence (AI) research more transparent and reproducible to accelerate the impact of their findings for cancer patients. The authors offer numerous frameworks and platforms that allow safe and effective sharing of data, computer code, and predictive models.
A recent study by IMDEA Networks Institute revealed that over 150 million websites among a billion tested contain sensitive and tracked content, despite European General Data Protection Regulation (GDPR) rules. The research uses machine learning classifiers to identify sensitive URLs on the web, finding that these pages are being track...
Researchers found that adult wolves form individualized social bonds with their human handlers and display attachment-like behaviors when separated. These findings suggest that the evolution of dog-human attachment may be linked to the common ancestor's social system.
A new study found that COVID-19 lockdowns led to significant improvements in air quality, averting an estimated 24,200 premature deaths in China and 2,190 in Europe. The study suggests that strong measures can be implemented to reduce air pollution and mitigate its impact on human health.
The PROSPECT ABSORB trial found PCI safe with favorable long-term outcomes for non-flow-limiting vulnerable plaques. Follow-up lumen areas were substantially enlarged in BVS-treated lesions compared to GDMT alone.
A new study led by Emily Kroska found that people who acknowledge and address their emotions during stressful times report lower stress levels than those who avoid identifying with their emotions. By maintaining relationships and engaging in valued activities, individuals can increase their psychological flexibility and reduce distress.
Researchers developed a process to measure COVID-19 antibody levels using enzyme-linked immunosorbent assays (ELISAs), which is faster, easier and less expensive than traditional methods. The ELISA tests had an 80% or greater probability of predicting virus neutralization titers.
A new study published in Scientific Reports found that lubricin, a protein that lubricates joints, increases in dogs with ACL injuries before signs of arthritis appear. The discovery has implications for human ACL and other orthopedic injuries, suggesting increased lubricin may be a biomarker for predicting future osteoarthritis.
Researchers will analyze stem cell activation with a focus on identifying novel mechanisms for how immature eye cells become mature visual cells. The goal is to develop regenerative therapies for diseases such as cataract, retinal degeneration, and heart disease.
A new metric, stopover-to-passage ratio, helps determine when birds fly over a site or stop to refuel or rest. The study reveals critical importance of habitats around the US Gulf Coast for sustaining migratory birds, with over half stopping at these sites.
The Gerontological Society of America invites media representatives to attend its 2020 Annual Scientific Meeting Online. The event will feature hundreds of scientific sessions and live discussions with researchers. Registration is free and provides access to all scientific sessions and the virtual exhibit hall.
Researchers have developed an ultra-sensitive hybrid nanothermometer that can detect small temperature changes in ambient conditions. The device uses a nitrogen-vacancy center in diamond and a magnetic nanoparticle to measure thermal signals with a precision of 76 microkelvin per second.
Scientists have developed a simple method to comprehensively assess spectrometer performance within seconds using only incoherent excess noise. This approach enables high-quality visible light OCT imaging with improved spectral resolution uniformity, revealing new insights into the mouse photoreceptor layer.
A new model can accurately identify children at highest risk of preventable death, considering multiple risk factors. The study found that socioeconomic membership and rural areas are significant predictors of mortality risk, highlighting the need for more targeted interventions.
The WVU School of Public Health is conducting a seven-week mask observation study with the CDC to estimate correct mask-wearing rates. The study found that 85.1% of observed individuals wore masks and 84% of those who did wore them correctly, but still a quarter didn't wear masks properly.
Honey bees rely on chemical cues from shared gut microbial communities to recognize nestmates, rather than genetic relatedness. This study shows that a bee's particular cuticular hydrocarbon profile is dependent on its microbiome.
A NYUAD study reveals that the β-actin protein plays a crucial role in activating genes essential for fat tissue formation. The discovery sheds light on the molecular basis of adipogenesis, which can help researchers develop new treatments for metabolic diseases such as diabetes and obesity.
Research shows that distracted learning significantly impairs students' attention, working memory, and learning outcomes. Educators can empower students to manage distractions by fostering an internal locus of control and promoting active learning. Strategies include removing extraneous devices, using work-reward systems, and incorpora...
The American Society for Radiation Oncology (ASTRO) will highlight groundbreaking studies and discussions on cancer treatment advances, COVID-19, and racial representation in radiation therapy clinical trials at its upcoming Annual Meeting.
A new software tool called ATLAS measures children's phonological awareness, a critical skill for literacy development. The study found that the software was effective in assessing over 1,100 children aged 3-7 with varying levels of speech and language impairment.
Topological photonics explores discrete states of light, similar to Fock states of electrons. The connection between the Maxwell and Schrodinger equations reveals new topological phases, including a Haldane model for valley Hall effect.
A new study by neuroscientists at Washington State University found that regular cannabis exposure in rats during pregnancy may cause long-term cognitive deficiencies, asocial behavior, and anxiety in their offspring. The research also revealed significant behavioral changes and cognitive deficits that persisted into adulthood.
Industry is shifting towards chemical recycling as a solution to tackle the problem of plastics, breaking down them into their building blocks. The process has environmental benefits but also raises concerns about reducing plastic consumption and increasing disposable packaging production.
A team of researchers at INRS has discovered a method to tune the spectrum of a laser to the infrared using a simple and much less expensive system: a hollow-core fiber filled with nitrogen. This approach delivers optical pulses shorter than those of the input laser and with high spatial quality.
Researchers found that dog personality has a 'stable' component, but individual dogs change at different rates, and some exhibit age-related impairments. Longitudinal studies showed that specific traits, like Problem orientation and Novelty seeking, change significantly during early life.
Extracellular vesicles (EVs) derived from endothelial cells have been shown to revive heart cells after a heart attack and keep them functioning while deprived of oxygen. The researchers demonstrated this functionality in human tissue using a heart-on-a-chip model.
A study found that vaccination with the measles-mumps-rubella (MMR) vaccine reduced the severity of COVID-19 in high-risk patients. Out of 36 cases, none required supplementary oxygen or respiratory insufficiency.
A comprehensive genomic analysis of neuroblastoma has revealed possible approaches for developing precision medicines to improve patient outcomes. The study found associations among common mutational traits that could be exploited therapeutically, including an association between a chromosomal mutation and oxidative stress.
A team of researchers has discovered the atomic-level mechanism that governs the length of heart muscle protein filaments, a critical component in maintaining healthy heart function. The study provides new insights into genetic mutations that cause devastating hereditary heart conditions.
A recent study shows that robot swarms can follow instructions to create paintings, using a system where an artist selects areas of the canvas to be painted a certain color. The resulting images are abstract and pleasing to the eye, with unique areas of color flowing into each other.
Researchers discovered that volcanic eruptions in Greenland and Iceland could have caused cooling episodes during the Eocene Epoch, solving a long-standing mystery about glendonites. This finding suggests that abrupt climate change is possible even in otherwise warmer climates.
A University of Reading mathematician is collaborating with Microsoft to study ancient mathematical problems, including Diophantine equations, to aid in the development of encryption software. The project aims to create more secure data protection against quantum computers that can solve complex mathematical problems quickly.
New UBC research reveals a need for improved training to address identity development issues in young people with psychosis. A survey of over 300 clinicians found that only half felt confident in addressing identity-related concerns, highlighting a gap in care.
Norbert regained tropical storm strength on Oct. 13, with estimated rainfall rates of up to 30mm/hour near its center. NASA's IMERG satellite product estimated rainfalls ranging from 5-15mm/hour throughout the storm.
Research shows that childhood maltreatment affects girls more than boys, leading to higher levels of low-grade inflammation. Girls who experienced abuse at a young age are at risk for significant health problems later in life.
A new display at Swansea University's Egypt Centre will showcase artefacts from Egypt, Greece, Rome, and other ancient civilizations to educate visitors about issues like identity, racism, and xenophobia. The exhibit aims to spark meaningful discussions on these topics, drawing from the rich material available in the ancient world.
Researchers at NIST have proposed a novel method to find dark matter by detecting its gravitational interaction with visible matter. A billion millimeter-sized pendulums would act as sensors, sensitive to particles ranging from 1/5,000 of a milligram to a few milligrams, covering the so-called Planck mass.
The article explores the debate on prioritizing racial minorities for COVID-19 vaccines, highlighting conflicts between public health recommendations and laws discouraging explicit consideration of race in policy decisions. The authors argue that strategic distribution can be done ethically and legally.
Researchers found that reusable plastic bags are the most eco-friendly option, followed by single-use plastic bags, due to their lower environmental footprint compared to single-use paper and multi-use cotton bags. Reusable plastic bags can be reused over 50 times before becoming environmentally detrimental.
A new set of assessment tools shows promise in capturing how the COVID-19 pandemic affects patterns of criminal activity. The toolkit uses resilience theory to examine the impact of exceptional events on crime patterns, with preliminary evidence linking the pandemic to increased domestic violence and declines in other forms of crime.
A new land surface model CAS-LSM was developed to assess impacts of climate change and anthropogenic disturbances on global river temperature and nitrogen transport. The model found increased river temperatures in tropical zones due to climate change, with power plants warming local rivers by up to 60% in Asia.
Researchers at Scripps Research have identified the PIEZO2 protein as a crucial part of how our body detects bladder fullness. The discovery sheds light on the mechanism underlying normal bladder function and may lead to new treatments for bladder control and urination issues, particularly among the elderly.
A systematic review of nine clinical studies involving 6,577 patients with COVID-19 found that obesity significantly increases the risk of severe illness and death. The study also highlights the importance of addressing obesity through public health policies to prevent COVID-19-related complications.
A new study in Japan found that caring for a loved one facilitates necessary end-of-life discussions, while experiencing a loved one's death does not. The experience of caregiving appears to be a key predictor of having end-of-life discussions, regardless of the caregiver's age.
The Society for Healthcare Epidemiology of America has updated its guidance for healthcare personnel living with HIV or hepatitis, citing low transmission rates and advances in treatments. The new recommendations aim to protect both patients and healthcare workers while ensuring privacy and health.
Despite expansion of NYC food assistance programs, high rates of food insecurity remain among low-income and minority communities. The latest survey found that 38% of New Yorkers worry about running out of food before they can buy more.
A meta-analysis of bivalirudin versus heparin in patients with myocardial infarction (MI) found that bivalirudin was associated with similar overall rates of 30-day mortality but lower rates of serious bleeding. In STEMI patients, bivalirudin use reduced all-cause mortality and serious bleeding.
Researchers have identified STAT3 as an important factor in emotional reactivity, establishing a link between the immune system, serotonergic transmission, and affective disorders. STAT3 deficiency reduces emotional reactivity in mice, suggesting its role as a molecular mediator in regulating emotional behavior.
Research suggests that genetic information can lead to over-diagnosis of depression, as individuals are more likely to recall their symptoms as severe when aware of their genetic predisposition. The study also found no correlation between genetic info and the actual severity of symptoms.
A randomized clinical trial found that different fitness strategies were effective for distinct subgroups of participants based on their personality and behavioral characteristics. These subgroups included extroverted and motivated individuals, less active and less social participants, and those who were less motivated and at-risk.
Research by Imperial College London finds severe morning sickness increases the risk of depression during and after pregnancy, affecting nearly half of women with hyperemesis gravidarum.
Scientists at NIST and the University of Maryland have developed a microchip technology that can generate a wide range of visible laser colors using near-infrared laser light. This approach enables precise control over wavelength, opening up new possibilities for applications in precision timekeeping and quantum information science.
A study suggests that whitebark pine's reliance on Clark's Nutcracker for seed dispersal and germination makes the partnership vulnerable to population declines. The researchers found a dramatic decline in Clark's Nutcracker within Mount Rainier National Park, where healthy whitebark pine populations have also declined.
Researchers are using artificial intelligence to integrate and analyze genetic, imaging, and clinical data from over 60,000 Alzheimer's patients. This project aims to identify precise diagnostic biomarkers and drug targets for the disease, which affects nearly 50 million people worldwide.
The University of Arizona College of Engineering professor has received a $1.82 million grant to improve the sensitivity and portability of her FLOWER technology, which detects ultra-low levels of disease particles, contaminants, and performance-enhancing drugs.
Researchers developed new AI models inspired by nature, reducing complexity and enhancing interpretability. These models can control vehicles with just a few artificial neurons, outperforming previous deep learning models in tasks such as autonomous lane keeping.
Researchers at University of California San Diego School of Medicine discovered a molecule called Girdin (GIV) that acts as a brake on macrophages. The GIV-mimic peptide can shut down immune cells' overreaction, supporting a mechanism critical for survival in mouse models of sepsis and colitis.
A new report identifies priority areas for ecosystem restoration, which could rescue land-based species and soak up vast amounts of carbon dioxide. Protecting these areas and restoring natural ecosystems can deliver significant biodiversity and climate benefits at a relatively low cost.
A recent scientific study led by the Centre for Neurology Studies at HealthTech Connex and Simon Fraser University reports breakthroughs in brain health recovery for Captain Trevor Greene, a Canadian veteran who survived an axe attack in Afghanistan. The study used innovative neuro-technologies, including Portable Neuromodulation Stimu...
A University of Gothenburg study finds that individuals who undergo obesity (bariatric) surgery have a higher average life expectancy compared to those given conventional treatment for obesity. The study, published in The New England Journal of Medicine, shows that bariatric surgery prolongs life expectancy by 3 years, but patients sti...
Research demonstrates that a stable bacterial microbiome exists within surface-sterilized perennial ryegrass seeds, which almost disappears as the plant matures but returns in a new generation of seed. The microbiome is influenced by soil type and can be used to track the movement of bacteria from parent to seed.
A study published in Science Communication found that watching high-quality, engaging media programs on climate change can reduce political polarization among Democrats and Republicans. Participants who were most engaged with the program showed greater perceptions of climate change risk and efficacy in taking action.
New research reveals that simple DNA-peptide interactions can generate a surprising diversity of compartmentalised higher-ordered phase behaviours, suggesting these polymers' primordial interactions may have helped create modern complex biological structures. The study found that changes in environmental conditions, such as salinity or...
Researchers at the University of Nevada, Reno have developed a novel COVID-19 rapid test using a nanotube-based electrochemical biosensor that detects SARS-CoV-2 virus in nasal swabs or exhaled breath. The test is simple, inexpensive, and non-invasive, with potential applications for diagnosis of other respiratory viral diseases.
A new study found that personal and psychological characteristics significantly impact progress in workplace wellness programs. The research suggests that tailoring nudges to an individual's behavior profile can unlock full potential, leading to improved outcomes. For some groups, ongoing incentives may be necessary to sustain motivation.
Researchers developed a risk-scoring calculation that adds blood and urine measures of kidney disease to the current standard method for assessing cardiovascular disease risk. The study found that adding these measures can result in large increases in cardiovascular disease-risk estimates among patients with severe kidney disease.
Scientists have created a new class of paints that can achieve the lustrous metallic look of gold or bronze without using metal flakes. The organic dyes can be dissolved in water and are stable over time, making them suitable for commercial use in ink-jet printers and potentially in electronic systems.
In a phase I clinical trial, vorinostat in combination with sirolimus or everolimus demonstrated improved outcomes for patients with heavily pretreated relapsed/refractory Hodgkin lymphoma. The treatment combination achieved an objective response rate of 55% and median progression-free survival of 5.3 months.
The International Antiviral Society-USA has updated its guidelines for preventing and treating HIV infection in adults, emphasizing the importance of antiretroviral therapy and pre-exposure prophylaxis. The new recommendations aim to improve treatment adherence and reduce HIV transmission.
Research shows that information campaigns and free seedlings can encourage diversification in oil palm plantations, increasing tree planting and survival rates. The study emphasizes the need for policies that consider both supply-side and demand-side impacts to reduce environmental degradation.
A new blood test, the Dublin-Boston score, accurately predicts which COVID-19 patients will develop a severe form of the disease. The score uses the ratio of pro-inflammatory IL-6 to anti-inflammatory IL-10 levels and can inform doctors on best treatment options.
A multidisciplinary team has bioengineered living cartilage-bone TMJ grafts using the recipient's own cells, demonstrating effectiveness in a clinically sized swine model. The grafts integrated well with surrounding tissues and provided biological and mechanical function similar to the native joint.
A Michigan State University researcher found that counterfeit identity documents are being sold on the open web, with most buyers seeking passports from European countries. The study also revealed that vendors use specific language to appeal to their audience and often offer discounts for referrals.
Researchers identified 132 heat-tolerant sweetpotato varieties, 65.9% of which are traditional local varieties, demonstrating good heat tolerance and potential for selection as high-yield, heat-tolerant varieties.
A group of 80 researchers argue that allowing low-risk populations to develop immunity while protecting vulnerable groups will not effectively control COVID-19. They emphasize the need for multi-pronged population-level strategies to protect societies and economies.
A systematic review found that the severity of infectious diseases peaks in school-age children, with young adults facing a higher risk of severe disease. The study analyzed data on 32 different infections and suggests 'immune aging' may start as early as young adulthood.
Researchers at Oregon State University found that viral infection is involved in coral bleaching, with bleached corals having a higher abundance of eukaryotic viruses and giant viruses. These findings suggest that viral assemblages shift between coral bleaching states.
A new €639,000 EU-funded project will develop cost-effective space cooling technologies powered by green technologies. The CO-COOL RISE consortium aims to accelerate the adoption of these innovations in the marketplace.