Researchers have developed an innovative GIS map to help building professionals achieve successful Plus Energy Building design. The European Climate and Cultural Atlas combines knowledge from social sciences and building engineering to provide insights into energy practices.
A new study by Stanford researchers found that nearly two-thirds of California prison residents who were offered a COVID-19 vaccine accepted at least one dose. Acceptance rates varied across different racial and ethnic groups, with Hispanic and white inmates having the highest acceptance rates.
A machine learning algorithm, FARDEEP, has been developed to assess an individual patient's risk of regenerative outcomes after surgical treatments of peri-implantitis. The study found that immune cell types central to microbial control are strongly correlated with superior clinical outcomes.
Scientists have discovered dramatic differences in gut microbiomes between ancient North American peoples and modern industrialized populations. The analysis of human paleofeces from dry caves reveals novel species of microbes and higher numbers of transposases, which may help microbes adapt to changing environments.
Patients who underwent bariatric surgery ten years ago reported that their eating habits and appetite remained affected, with reduced cravings for unhealthy foods. However, they also described struggling to manage their lives, including supporting overweight children, due to ongoing guilt and self-blame.
A new theorem limits the use of quantum machine learning to learn processes like black holes, highlighting its fundamental limits. However, most physical processes are structured enough that they don't resemble random ones, making the impact less severe.
Researchers used genetic engineering tools to create a virus that can enter specific neurons and insert new genetic code, inducing modified protein production. In mice tests, the alteration was sufficient to modify brain activity, indicating potential biomarker for psychiatric disorders like schizophrenia and autism.
The RIO Journal has published over 300 research outcomes since its launch in 2016, including early ideas, grant proposals, data management plans, and project reports. These non-traditional publications have shown significant engagement and societal impact, with authors mapping their articles to the Sustainable Development Goals.
A new Northwestern Medicine study of placentas from vaccinated patients found no evidence of injury, supporting the safety of COVID-19 vaccines in pregnancy. The study adds to growing evidence that vaccination can protect fetuses without increasing harm.
Researchers at University of Queensland develop gene therapy to block scar formation by targeting SOX9 gene, promising benefits for burn patients and others with significant scarring. The study uses siRNA technology to reduce scarring in animal models, paving the way for potential human treatment.
Researchers created a tiny, wireless chip that uses ultrasound to monitor body processes, enabling the development of miniaturized implantable medical devices. The team achieved volumetric efficiency with their design, paving the way for chips that can be injected into the body and communicate wirelessly.
Degrowth scenarios, focusing on global North reduction in energy and material use while maintaining wellbeing, have clear advantages over established pathways. Combining social change with technological improvements can achieve net-zero carbon emissions more easily.
By vaporizing metals within a magnetic field, UC Riverside engineers direct the reassembly of metal atoms into consistent shapes and surfaces. The approach enables manipulation of particle assembly, producing string-like aggregates or globular clusters with tunable properties.
Researchers will investigate potential mechanisms using mouse models and systems biology approach to identify new drug targets for Alzheimer's disease. The study aims to understand how altered mitochondrial calcium transport contributes to neurodegeneration and disease progression.
Researchers created a design for an electronic hardware system that directly replicates network architectures, solving complex puzzles rapidly and with minimal power consumption. This new approach uses race logic to encode and process information as time signals, reducing the need for bit flips and thus energy expenditure.
The study found that spinal cord injury-dependent effects on bacteria and viruses were observed, with beneficial bacteria decreasing and potentially pathogenic bacteria increasing. Functional microbial genes encoding essential pathways for central nervous system function were also reduced after spinal cord injury.
Researchers at McGill University studied bacterial movement through microfluidic environments to understand their navigational 'strategies'. The findings have implications for diagnosing infectious diseases, developing devices for genomics and bio computation, and maintaining human health.
The Hong Kong Society of Rheumatology has developed consensus recommendations for COVID-19 vaccination in adult patients with autoimmune rheumatic diseases. The guidelines address concerns about vaccine efficacy and safety, as well as considerations for immunosuppressed patients.
Inkjet printing of metal nanoparticles forms layers with functional anisotropy, causing electrical conductivity to vary between horizontal and vertical directions. Researchers discover that organic chemical residues in the inks are responsible for this effect, enabling new techniques to overcome it.
Research published in BMJ Open suggests that long-term use of prescription medications for insomnia does not improve sleep quality or duration in middle-aged women. Despite this, many people still take these drugs due to chronic insomnia.
A new study published in the British Journal of Obstetrics and Gynaecology found that a combined drug treatment for missed miscarriage is more effective and cheaper than current standard medication. The treatment, combining mifepristone and misoprostol, was on average £182 cheaper per successfully managed miscarriage.
A recent study published in Molecular Biology and Evolution reveals that the DNA replication machinery of Mimivirus, a giant virus, is ancient and evolved over time. The research suggests that Mimiviral genes related to DNA replication are subject to purifying selection, indicating their essential role in the organism's survival.
A new study found that Massospondylus carinatus, a medium-sized southern African dinosaur, had growth variations from year to year. The dinosaur's growth directly responded to environmental conditions, with significant increases in good years and minimal growth in bad years.
Researchers from Peter the Great St.Petersburg Polytechnic University developed a methodology for assessing cyber risks in Smart City infrastructure. The new approach analyzes asset types, threats, and risk values using a quantitative approach, demonstrating superiority over existing methods.
A new study reveals that many UK farmers are not prioritizing adapting to the effects of climate change due to uncertainty and focus on short-term profitability. However, innovative practices such as improving soil health and adopting risk-spreading strategies can help build resilience within farming businesses.
Researchers at Huntsman Cancer Institute discovered that nicotinamide phosphoribosyltransferase (NAMPT) plays a key role in how immune cells fight melanoma tumors. The study found that disrupting the NAMPT pathway impairs antitumor function, and novel therapies targeting this pathway may lead to improved outcomes for patients.
A new paper found that cleaning local lakes and waterbodies can slow climate change and save trillions of dollars by reducing methane emissions. The study estimated the costs of global climate change due to eutrophication from 2015 to 2050 to be as much as $81 trillion.
A Trinity College study found people homeless in their 20s-40s experience high levels of physical and mobility problems, with only one-third able to climb hospital stairs. The study suggests that targeted health and accommodation services are necessary for this vulnerable group.
Researchers developed a global GNSS seismic monitoring system that can rapidly assess earthquake magnitude and fault slip distribution within seconds. This system can provide early warnings for large earthquakes and tsunamis, buying more time for evacuations and infrastructure shutdowns.
A new study found that zoo YouTube videos focus disproportionately on mammals, with only 3% of content dedicated to conservation. However, the study also notes an increase in conservation-focused videos in recent years, highlighting the potential for social media to support global conservation education.
The review explores recent strategies in surface functionalization, their specific biomedical applications, and comparative toxicities with non-functionalized metallic nanoparticles. It discusses the challenges for metallic NPs to undergo human clinical trials due to their aggregation and toxic nature.
Researchers propose novel sulfur cycle model incorporating volatile organosulfur compounds to explain global occurrence of superheavy pyrite. The Cryogenian interglacial interval saw sulfidic oceans with pervasive VOSC generation, leading to vertical isotopic gradients and superheavy pyrite precipitation.
Researchers at Gladstone Institutes have adapted CRISPR-Cas9 technology to edit human monocytes, a type of white blood cell that plays key roles in the immune system. The study shows the potential utility of gene editing for understanding how the human immune system fights viruses and microbes.
A low-cost box fan air cleaner can greatly decrease airborne virus particles in public school classrooms by drawing in contaminated air and filtering out clean air. Placing the air cleaner near an HUV or other ventilation unit is most effective in reducing aerosol spread.
A study from the University of Surrey found that 67% of UK adults are overweight or obese, with time-restricted feeding showing potential to combat obesity. More than 400 participants believed they could reduce their 'feeding window' by three hours if associated health benefits were clear.
A team of researchers aims to increase microorganism's ability to convert CO2 into methane for efficient production of sustainable fuel. The ReMeSh project will examine bio-electrochemical systems and accelerate electron transfer to microbes.
A new study published in The Lancet Diabetes & Endocrinology found that BMI cut-offs used by the World Health Organization and UK's National Institute for Health and Care Excellence are not suitable for adults from Black Asian and Minority Ethnic backgrounds. The research, which included over 1.5 million people, shows that these groups...
Researchers at Sandia National Laboratories used advanced computer simulations to study the spread of COVID-19 through droplets in the air. Their findings show that protective measures like masks and social distancing are crucial in reducing transmission. The studies also revealed that even with face coverings, smaller particles can pe...
Researchers found that participants overestimated minority groups and looked more often at these groups, even in quick visual scans. This bias occurs regardless of social context and is driven by a fundamental feature of human perception
Patients who attended shared medical appointments lost more weight over 24 months compared to those receiving usual care. Additionally, they showed better outcomes in managing chronic conditions such as high blood sugar, cholesterol and blood pressure.
Researchers found that moving baseline targets is a key driver of increasing budgets for federal government technology programs. However, componentizing programs into smaller work units and increasing competency in program management can result in significant cost savings.
A recent study led by NSU researcher sequenced the leopard genome, showing distinct genetic patterns between African and Asian populations. The analysis suggests that all African leopards should be considered a single subspecies due to abundant gene flow across Africa.
Menefeeceratops sealeyi, a newly described horned dinosaur, lived in New Mexico 82 million years ago and is one of the earliest known ceratopsid species. The discovery provides important insights into the evolution of ceratopsid dinosaurs and their evolutionary relationships.
A virtual weight-management support group during lockdown resulted in clinically meaningful weight loss for 27% of participants, associated with reduced risk of diabetes and other chronic conditions. Average weight loss was 7.4lbs or 3.5% of body weight.
A new four-drug combination treatment has shown promise in preventing cancer metastasis without triggering drug resistance. The treatment targets multiple pathways to suppress cancer cell spread and may help identify patients who would benefit from such therapy.
Researchers used machine learning to predict patient outcomes using routine clinical information, identifying factors that determined which patients were likely to get worse. The AI model improved oxygenation in only 44% of patients, while proning was ineffective in those with blood clots or inflammation.
Rheumatic heart disease (RHD) in Africa can be controlled through increased coverage of interventions like early detection and cardiac surgery, saving around 70,000 lives by 2030. The PEN-Plus package of integrated disease management offers a high return on investment.
Researchers developed a scanning quantum sensing microscope that maps local electric fields with a spatial resolution of ~10 nm and sensitivity close to an elementary charge. The technique allows for reversible control of single NV's charge states, enabling the purification of NV's electrostatic environment.
A study of 55 hospitals in Queensland, Australia found that implementing a minimum ratio of one nurse to four patients resulted in a 7% drop in death and readmission rates, and a 3% reduction in length of stay. The policy also generated significant cost savings, with estimated annual savings of $69 million.
Researchers at UC San Diego have developed a novel genetic sensor called CopyCatcher to detect precise CRISPR editing in cells throughout the body. The study shows promise for treating genetic disorders such as blood diseases, vision and hearing problems, and muscular dystrophy.
PIF proteins play organ-specific roles in regulating cell division in apical hooks and cotyledons, but not in hypocotyls. Cytokinesis is involved in the apical hook opening, and PIF proteins directly bind to the promoter of BUB3.1, a key regulator of microtubule reorganization during cytokinesis.
Scientists have discovered a way to control brain circuits using a protein called parapinopsin, found in lamprey. This breakthrough could lead to new treatments for mood disorders and unwanted behaviors.
A global observational study reveals that COVID-19 patients hospitalized globally exhibit a significant prevalence of neurological manifestations, often associated with higher in-hospital death rates. The findings underscore the importance of considering neurological complications in COVID-19 patients worldwide.
A study of nearly 1,100 pregnant women and 9,800 non-pregnant patients found that pregnant women with severe COVID-19 infections have significantly lower death rates than their non-pregnant counterparts. However, differences in health conditions between the two populations may affect mortality risk.
The Saker Falcon's population has recovered in Bulgaria after a 20-year conservation effort, with observations confirming at least one breeding pair. The species was reintroduced in 2015 and bred successfully, paving the way for further releases to restore the population.
A new online game and campaign using 'pre-bunking' tactics have been shown to boost people's confidence in detecting misinformation about COVID-19. The Go Viral! game, launched by the University of Cambridge, increases players' ability to perceive manipulativeness compared to genuine news.
Researchers have developed a novel nano-carrier to deliver the Chinese medicine compound gambogic acid, enhancing its anti-cancer effect and reducing off-target toxicity. The treatment shows promise in treating triple-negative breast cancer with improved efficacy and reduced damage to organs.
MIT researchers have generated the most accurate gene annotation of the SARS-CoV-2 genome, confirming six new protein-coding genes and discovering a rare gene-within-a-gene. The study also analyzed over 1,800 mutations, revealing regions that may help the virus evade the immune system.
Researchers discovered that manganese-enhanced MRI scans provide more accurate details of heart function than traditional methods, potentially increasing survival chances. The study suggests that early detection within the first few hours of a heart attack can optimize treatment regimes and regulate cardiac muscle changes.
A Columbia Engineering/UCLA team discovers phase precession in the human brain, allowing neurons to signal information through precise timing. This finding has implications for understanding brain function and creating brain-machine interfaces.