A study of post-mortem examinations found that COVID-19 patients had diffuse alveolar damage, thrombosis in major organs, and kidney injuries. The research aims to inform clinicians on treating complications and develop new monitoring strategies.
Scientists have developed a technique that can detect and quantify viral RNA in living cells, as well as minor changes in RNA sequences. This could help identify superspreaders and understand how viruses evolve to become more infectious.
Fatty acid binding proteins (FABPs) are chaperones that coordinate fatty acid transport between cells. Research by University of Louisville immunologist Bing Li reveals their role in lipid metabolism, obesity, and disease development.
LONs have shown outstanding properties in designing membrane-anchored biosensors and synthetic membrane channels due to their information-transfer and self-assembly abilities. They also have great potential in making contributions to developing new therapies and controllable nanoreactors.
A new study published in Nutrition and Metabolism found that an eight-week very low-carbohydrate diet improved body composition, fat distribution, and metabolic health in older adults with obesity. The diet also preserved skeletal muscle mass without intentional caloric restriction.
A new modular iridium catalyst allows unprecedented control over fatty acid derivative modification, enabling the production of valuable compounds from renewable resources. This breakthrough opens up new avenues for pharmaceuticals and plastics synthesis.
Researchers at Johns Hopkins Bloomberg School of Public Health found that states with handgun purchaser licensing laws had lower firearm homicide and suicide rates. Connecticut's law, enacted in 1995, was associated with a 28% decrease in firearm homicides and a 33% decrease in firearm suicides.
A comprehensive pediatric study shows children can carry high levels of the virus and spread infection, contradicting previous assumptions. The study's findings have implications for reopening schools and daycare centers, highlighting the need for increased precautions to keep kids, teachers, and staff safe.
Researchers developed a novel thermometer based on quantum entanglement that can accurately measure ultra-cold temperatures in clouds of atoms, known as Fermi gases. The new method uses a probe atom to infer temperature by exploiting the unique properties of fermions at extremely low temperatures.
Cyclohexyl phenyl sulfide cleavage studied for degradation of sulfur-containing heavy oil. Copper compounds are found to be the most effective catalysts for heavy oil extraction, followed by cobalt and nickel.
A new vaccine candidate has been developed for HHV-6B, a virus that causes exanthem subitum in infants. The vaccine targets the gH/gL/gQ1/gQ2 complex and induces strong immunity against the virus. Animal experiments have shown that the vaccine prevents HHV-6B infection and activates dendritic cells to induce innate immunity.
A team of researchers from the University of Kansas blames a series of supernovae explosions for triggering the end-Devonian extinction event. The ionizing radiation caused internal damage in large animals and organisms, leading to mass extinctions of armored fish and trilobites.
A new kirigami-based shoe sole has been designed to reduce the risks of slips and falls by adjusting as a person steps, increasing friction with pop-up spikes as necessary. The study found that the new grip could achieve a greater friction than standard winter boots by two- to three-fold.
Three experts, Professor Maria-Luisa Brandi, Dr. Lee Joon-Kiong, and Professor Ego Seeman, have been awarded the IOF President's Award for their contributions to osteoporosis research, education, and public awareness. The award recognizes their efforts to expand the Foundation's programs and outreach in the scientific and policy spheres.
A small Italian town's transformation into a major hub for medical device production is attributed to one man's entrepreneurial spirit and vision. The study, led by Professor Simone Ferriani, highlights the 'anchor entrepreneurship' framework as a catalyst for rapid development in small communities.
Scientists at Okayama University developed a new technique to analyze dendrite formation in rechargeable batteries, improving safety. They discovered that quasimetallic Li clusters act as a buffer for dendrite formation in hard carbon electrodes, providing valuable insight into overcoming lithium dendrite formation limitations.
Researchers discovered that Klotho protein deficiency causes aging-associated hypertension through high salt intake, with supplementation preventing hypertension development. Klotho levels may serve as a predictive marker for hypertension risk.
Researchers studied 25 immature chimpanzees learning to use tools, discovering they acquire complex termite-extracting skills over time. The study provides insights into how technology evolved in human culture and highlights the sophistication of Central African chimpanzee tool-using skills.
A new study identifies two genes, TMEM106B and RBFOX1, that regulate gene expression in the aging brain and are linked to both Alzheimer's disease and Limbic-predominant Age-related TDP-43 Encephalopathy (LATE). The findings suggest a shared molecular basis for these diseases, which may lead to new treatments and prevention strategies.
Researchers examine the impact of unconventional monetary policy on bank risk-taking in the syndicated loan market, finding no additional interest rate reduction for riskier firms. This suggests that loose lending is not a concern under unconventional monetary policy measures.
A new study of 181 patients found that about 15% test positive for one or both newly discovered antibodies that attack the point of communication between nerves and muscle. Those who tested positive tended to be sicker when diagnosed and have a more severe disease course.
A region-wide study by Penn State researchers confirms that invasive shrubs have an advantage over native shrubs, contributing to their proliferation. The study found that invasive shrubs maintain leaves for 77 days longer than native shrubs, giving them a competitive edge in acquiring energy and creating shade.
Scientists at ESRF discover new type of critical point in liquid sulfur, allowing for better understanding of liquid-to-liquid transitions and their applications. This breakthrough could open doors to studying the complexity of other important systems like water.
A recent study by Vaishali Bhaumik and Dr Krushnamegh Kunte reveals contrasting effects of migration and dispersal on flight morphology in butterflies. Female butterfly populations that disperse over short distances have a higher egg load, but this declines rapidly as their thorax size increases, enabling stronger flight muscles.
The HEARTROID platform will assist the TTDD lab in validating device performance with pulsatile and anatomically precise 3D printed models, accelerating surgical device development. The partnership aims to create novel medical devices that enhance native biological functions.
A Rutgers study found that young gay men who experience healthcare discrimination or have providers lacking in knowledge about gay men's health issues are more likely to miss out on screenings and care. Creating safe spaces for disclosure can build trust and improve access to relevant services.
Researchers at the University of Alberta have found a way to accelerate nerve regrowth in trauma patients by three to five times, leading to better outcomes. The treatment, known as conditioning electrical stimulation (CES), involves electrically stimulating nerves before surgery, causing them to regenerate faster.
Researchers found that brain function remapping is impaired in Alzheimer's disease patients, causing spatial memory impairment. Improving brain remapping function may reverse spatial memory impairment using deep brain stimulation methods.
A new study reveals that female Emigrant butterflies selectively burden themselves with eggs during long-distance flights, whereas males travel light. This disparity stems from differences in predictability of habitat patches and larval host plants between migrating and dispersing species.
Researchers estimate that sustainable seafood production can increase by 21-44 million metric tons annually, accounting for 12-25% of global animal protein needs by 2050. Policy reforms and technological improvements can help address sustainability concerns and environmental limitations.
Researchers at Yokohama National University developed a new method to produce entangled photons compatible with quantum memories, allowing for long-distance quantum communication through optical fibers. This breakthrough could enable the creation of a quantum internet linking quantum computers.
The University of Nottingham is launching two new projects using satellite Earth Observation technology to tackle global development problems. The first project aims to develop an anti-trafficking system to support efforts in Uganda, while the second project focuses on monitoring sargassum seaweed affecting Mexico's Caribbean Coast.
A new database of 40 breast cancer cell lines will help speed the development of new gene-targeted therapies by providing genomic and proteomic information. Researchers aim to identify functional genes that drive cancer growth and develop targeted therapies based on unique gene changes in each patient's cancer.
Researchers have found that the shape and structure of muscle fibres in the heart impact its performance and risk of heart failure. The study, published in Nature, reveals how these 'trabeculae' work and develop, and their importance to human health.
Researchers at Hackensack Meridian Health identified a drug that improves survival in critically ill COVID-19 patients. The study found a statistically significant decrease in hospital-related deaths among those who received tocilizumab, a monoclonal antibody used to treat rheumatoid arthritis and cancer treatments.
Salk Institute scientists develop transplantable human insulin-producing pancreatic cell clusters that evade the immune system, providing sustained blood glucose control without immunosuppressants. The cells were created using stem cell technology and a protein called WNT4 to induce a genetic switch that makes them functional.
Researchers at Weizmann Institute of Science identify key molecule regulating biomolecular messaging in nerve cells, which plays a role in chronic pain. Targeting this molecule, importin alpha-3, could provide new options for treating chronic pain with fewer side effects.
The virtual WCO-IOF-ESCEO 2020 Congress featured over 210 live and pre-recorded sessions on new clinical research and advances in osteoporosis, osteoarthritis, and related diseases. The Congress attracted a record number of registrants and was accredited by the EACCME with 16 European CME credits.
Researchers developed a low-cost, visible-light activated coating for water filtration membranes that breaks down foulants and renders the membrane clean. The coating increases photocatalytic efficiency under sunlight by 24-fold compared to regular titanium dioxide.
Researchers at West Virginia University are developing a methane mitigator system to reduce greenhouse gas emissions from natural gas production sites. The goal is to decrease environmental impact and ensure compliance with emerging emissions restrictions, while improving overall system efficiency.
The Honesty Project will investigate the science of honesty, examining what predicts honesty in various situations and how it affects relationships and institutions. Researchers aim to develop ways to foster honesty in daily life, despite the consequences of dishonesty being often met with resignation.
Researchers at KIST developed a low-cost membrane material and catalyst to decompose ammonia into hydrogen and nitrogen, producing high-purity hydrogen. The new technology enables continuous production of pure hydrogen with reduced energy consumption and cost.
A single dose of targeted radiotherapy during surgery is comparable to conventional radiotherapy in efficacy for most women with early breast cancer. This reduces the need for extra hospital visits and minimizes side effects. The long-term results show no significant difference in survival or likelihood of cancer recurrence.
Researchers analyzed genetic studies and found no causal link between sleep patterns and Alzheimer's disease. However, they discovered a small association between certain sleep characteristics and increased or decreased risk of developing Alzheimer's, including being a 'morning person' and having lower insomnia risk.
A new study published in The American Journal of Medicine estimates that one out of every 100 American children will die from firearms if current death rates continue, while one out of every 70 will die from drug overdoses. The study aims to educate the public and policymakers about the impact of firearm and overdose deaths.
Research using UK Biobank data found that people who experienced childhood maltreatment were five times more likely to have four or more long-term health conditions. The study also linked childhood maltreatment to increased social isolation and poor self-rated health in adulthood.
A comprehensive study of four salmon species in Alaska found that they are returning to rivers smaller and younger than in the past. This decline affects both commercial and subsistence fisheries, as well as the nutrient delivery to inland areas, fertilizing forests and freshwater ecosystems.
The study found that Laotians rely heavily on wildlife for food and income, driving the illegal trade of terrestrial vertebrates. Approximately 90% of respondents confirmed using wildlife products, highlighting the need for conservation measures to protect native species.
Researchers found that COVID-19 patients with hypoxia responded positively to icatibant treatment, with improved oxygen levels and reduced need for supplemental oxygen. A follow-up study is underway to explore the effectiveness of a new drug, lanadelumab, which may offer longer-lasting benefits.
UT Arlington faculty members Stephanie Rasmussen and Ericka Robinson-Freeman received the UT System Board of Regents Outstanding Teaching Award for their dedication to student success. The two professors were recognized for innovative course development, classroom expertise, and student learning outcomes.
Researchers have discovered that pumice rafts are delivering a surge of new coral and reef-building organisms to the Great Barrier Reef, boosting its health. The rafts, formed when frothy magma cools rapidly, carry a diverse array of marine life across thousands of kilometers.
A new study has identified a better treatment option for arteriovenous fistulas used in hemodialysis, reducing the need for repeated hospital visits and procedures. The drug-coated balloon angioplasty treatment has shown promising results, with patients being 25% more likely to have a functioning access point after 6 months.
A new study by University of Copenhagen researchers found that childhood adversity increases the risk of premature death in early adulthood. The most vulnerable children experienced a mortality rate 4.5 times higher due to increased risks of suicide, accidents, and cancer.
Researchers at the University of Bonn discovered a protein that influences cell communication in vascular cells. The study found that an RNA-binding protein acts as a gatekeeper, controlling the release of microRNAs that promote regeneration. This breakthrough offers new hope for treating diseases like arteriosclerosis.
The NASA JPL team is using deep learning to develop software for future Mars rovers, which will enable them to travel farther and explore more of the planet. The team has been training machine learning models on the Maverick2 supercomputer and developing novel capabilities such as Drive-By Science and Energy-Optimal Autonomous Navigation.
A new study suggests that following an alternate Mediterranean or Alternative Healthy Eating Index diet pattern may be linked to fewer non-motor symptoms such as constipation, daytime sleepiness and depression. The researchers found a strong relationship between healthy diet adherence and reduced risk of these preceding symptoms.
Adding corticosteroids to standard intravenous immunoglobulin treatment for high-risk Kawasaki disease patients can boost initial response and prevent complications. The combination approach reduced the need for a second course of therapy by 35% and the risk of coronary artery abnormalities by 47%.
PIM kinases promote metastatic growth by regulating actin fibre formation in the cytoskeleton, supporting PIM-targeted therapies to prevent metastasis. The study provides critical information on factors regulating cancer cell motility, essential for preventing cancer spread.
Physicists at the University of Warwick demonstrate that applying a noble metal to a crystal's surface can excite its structure, enabling new electrical effects such as converting movement and heat into electricity. This technique has great potential for use in sensors, energy conversion, and mobile technologies.
A study found that climate change is causing a phenological mismatch between bees and flowers, with bees emerging later than flowers reach their peak flowering time. This disruption has the potential to reduce abundance of pollinators and plants, leading to reduced fitness losses for mutualist species.