A new study from the University of Oxford reveals that a molecule called glycosyrin, produced by the bacterium Pseudomonas syringae, mimics galactose to suppress plant immune responses. This finding has potential medicinal applications and highlights the complex strategies used by bacteria to manipulate host plants.
Researchers explore structural and functional characteristics of Russula vinosa Lindblad polysaccharides, finding potential applications in pharmaceuticals and functional foods. The study reveals that structural differences between polysaccharides influence immunomodulatory activities.
SourceJournal of Bioresources and Bioproducts·JournalJournal of Bioresources and Bioproducts·TypeExperimental study·DateJan 29, 2025
A new study has identified three genes, MANBA, TNFRSF13B, and EEF1A1, as crucial in the regulation of IgG galactosylation, a trait associated with ageing. The research used GWAS to analyze IgG glycosylation phenotypes in a large sample size, increasing the understanding of this complex posttranslational modification.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJan 3, 2024
Researchers discovered a gut bacteria that helps reduce insulin resistance and protect against diabetes. The study found that a specific bacteria, Alistipes indistinctus, consumed excess monosaccharides in the gut, lowering blood sugar levels and reducing insulin resistance.
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Researchers at PLOS discovered that a diet change from glucose to galactose can slow down aging in yeast, similar to the benefits of caloric restriction. The study found that this dietary shift maintains a youthful profile in ageing yeast cells.
Researchers at Gladstone Institutes have made a groundbreaking discovery about how neurons consume and metabolize glucose, a process crucial for maintaining normal energy levels. The study found that neurons rely on glycolysis to break down glucose, and its disruption can lead to severe learning and memory problems in mice.
SourceGladstone Institutes·JournalCell Reports·DateApr 20, 2023
Researchers at USC Viterbi's Mork Family Department of Chemical Engineering and Materials Science have discovered a fatal vulnerability in many cancer cells: their inability to adapt to alternative sugars like galactose. The discovery could lead to new metabolic treatments for cancer, targeting cells with specific genetic mutations.
SourceUniversity of Southern California·JournalJournal of Cell Science·DateJun 16, 2020
Professor Nagendra Shah received the prestigious International Dairy Foods Association Research Award in Dairy Foods Processing for his groundbreaking work on GABA-producing lactic acid bacteria. His team's discovery has great commercial significance in developing dairy foods with anti-hypertensive activity.
University of Illinois scientists develop a new strain of yeast that converts seaweed into biofuel more efficiently, cutting production time in half. This breakthrough improves the economic feasibility of marine biofuels and offers a healthier product.
SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalApplied and Environmental Microbiology·DateAug 29, 2011
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A University of Illinois research team has developed a strain of yeast that can efficiently ferment galactose, a key component of seaweed, making it a viable option for biofuel production. The discovery improves the economic viability of marine biofuels by increasing fermentation rates and reducing production costs.
SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalBiotechnology and Bioengineering·DateDec 15, 2010
Scientists have developed flies with genetic changes similar to those found in patients with galactosemia, allowing researchers to study the disease and develop potential treatments. These models can help understand how sugar metabolism leads to disease and open the door to novel drug discovery.
SourceThe Company of Biologists·JournalDisease Models & Mechanisms·DateJun 1, 2010
Scientists have discovered a new type of genetic variation that suggests natural selection can act on gene networks, maintaining alternative states within a single species. This finding may be crucial for understanding how pathogens adapt to new stresses and could provide significant advantages in the battle against diseases.
Researchers discovered that E. coli has a protein that recognizes the rarer furanose form of galactose, allowing it to exploit this additional nutrient source. This adaptation enables E. coli to grow faster and persist in the gut at the expense of other species.
SourceUniversity of York·JournalJournal of Biological Chemistry·DateNov 12, 2009
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UC San Diego bioengineers identified a previously unknown mechanism allowing yeast to shut down galactose metabolism when glucose is present. This discovery provides new insights into gene regulation and could lead to understanding of human metabolic diseases like diabetes.
SourceUniversity of California - San Diego·JournalNature·DateJul 30, 2008
A team of researchers at UCSD has quantified more noise in gene expression, discovering significant fluctuations within individual cells and variations between identical cells. This study provides a mathematical description of 'extrinsic noise,' a larger component of variation in gene expression.
SourceUniversity of California - San Diego·JournalNature·DateDec 21, 2005
Researchers at Cold Spring Harbor Laboratory have discovered that Spot 42, a small RNA, differentially regulates gene expression in the E. coli galactose operon through an antisense mechanism. The study provides mechanistic insight into the process and answers long-standing biological questions.
SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateJun 30, 2002
Researchers at Penn State College of Medicine have discovered that a protein previously thought to be in the nucleus resides in the cytoplasm, correcting a scientific theory since 1992. This finding offers new parameters for understanding gene switches and their role in human diseases.
SourcePenn State·JournalProceedings of the National Academy of Sciences·DateJun 24, 2002
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