Articles tagged with Hormones
UVA researchers will use AI-assisted tools to develop a digital model showing how hormone differences impact medication effectiveness in women. The model will be tested on bacterial vaginosis and metabolic dysfunction-associated steatotic liver disease, with the goal of creating personalized predictions and more targeted drug therapies.
The European Society of Endocrinology is urging policy action to address a widening gap between care demand and workforce capacity. The endocrine workforce faces significant stress, burnout, and limited time for research, threatening timely and high-quality care.
A new preclinical study found that glucocorticoid-rhythm disruption concentrates insulin resistance in skeletal muscle while preserving key insulin responses in fat tissue and liver, leading to a different type of obesity. This allows fat tissue to continue storing lipids, while the liver remains largely protected from fat accumulation.
A new ERC-funded project at Aarhus University aims to investigate how hormones, stress, and genetic factors influence women's coronary arteries. The project will develop new models to explain why certain cardiovascular diseases affect women differently from men, and may lead to personalized rupture-risk maps and improved diagnosis and ...
The INSULIN Act would cap out-of-pocket insulin costs at $35 per month for people on private insurance, establishing a resource center and hotline for uninsured individuals. The Endocrine Society applauds the bipartisan bill, which aligns with its Insulin Access and Affordability Position Statement.
A new study suggests that estrogen hormone treatment combining estriol and progesterone may help alleviate 'brain fog' symptoms in menopausal women. The study found significant reductions in cognitive symptoms such as memory, concentration, and problem-solving after 12 months of treatment.
A telemedicine-supported home-injection model for patients with breast cancer has shown to reduce treatment burden by improving convenience and saving time. Most patients who completed home injections chose to continue this approach beyond the pilot, but barriers such as insurance denials and higher copayments may limit its broader imp...
A new book by University of Virginia Health System expert Daniel J. Cox outlines a practical alternative to medication for managing pre-diabetes and type 2 diabetes. The GEM program emphasizes smart eating, physical activity, and listening to the body to regulate blood sugar levels.
A Rutgers study reveals that high school students who engage with beauty-related content on social media use more personal care products containing hormone-disrupting chemicals. The study found a significant correlation between time spent on social media and increased product usage, with girls reporting higher median daily product use.
Researchers found that exercise-induced molecular changes contribute to neuronal health, improving movement and quality of life in PD patients. Exercise types such as aerobic exercises, resistance training, balance training, and multimodal exercise were found to be helpful in reducing falls, disabilities, and improving brain function.
Researchers discovered a strong link between environmental variation and thyroid hormone signaling in reef fish, enabling them to adapt to changing habitats. The study found that habitat impacts development by altering gene expression and metabolic profiles, giving animals more flexibility when their environments change.
Researchers found that estradiol inhibits mouse THIK-1 by approximately 40%, depending on residues in the pond region of the channel. This effect has potential physiological or pathological significance for THIK-1 variants, with implications for microglia and macrophage function.
Research investigates how bioactive molecules in human milk shape infant metabolism and informs formula development.
Combining cemiplimab, fianlimab, and paclitaxel-based neoadjuvant chemotherapy improved pathologic complete response rates in high-risk -negative breast cancer. Patients with the ImPrint immune signature showed enhanced sensitivity to the combination.
A study published in Science Advances found that prolactin activates a brain pathway that makes time with newborns feel rewarding rather than necessary. This rewiring of the brain's reward system helps explain how mothers' thoughts and feelings change during pregnancy and after birth.
Research at Oregon State University found that frequent cannabis users wake up with more cortisol in their system, indicating a possible dysregulation of the body's daily stress response. This could lead to impairments in daily stress rhythms and a cycle of more cannabis use.
Researchers have discovered a link between endometriosis and unique hormone patterns, which could lead to a simple, non-invasive diagnostic blood test. The study found that individuals with endometriosis exhibit distinct levels of androgens, including testosterone, in their blood.
A new study found that women taking hormone-containing birth control pills experienced higher rates of binge-related eating compared to those taking hormone-free pills. The research, published in JAMA Network Open, suggests that the hormones in birth control pills may contribute to increased emotional eating.
A new study found that prenatal oestrogen levels in mothers are positively related to their newborn's head circumference. The researchers also discovered that this influence is stronger for boys than girls, shedding light on the evolutionary drive for larger brains in humans.
A Drosophila study shows that macrophages detect nutritional stress caused by high-sugar diets and send a signal to the endocrine system to delay development. This delay helps buffer the impact of the diet on growth, allowing organisms to reach adulthood in better condition.
A new study found that higher levels of glyphosate and a related compound were associated with changes in hormones supporting pregnancy and fetal growth. Glyphosate is widely used herbicide linked to hormone disruption as one possible pathway.
A study of 165,832 women found that later menarche is associated with an increased risk of tobacco use disorder and various conditions, including digestive issues, heart problems, and brain disorders. The researchers suggest a shift in perspective to recognize childhood influences as the primary cause of adult health problems.
A retrospective cohort study found that menopausal hormone therapy significantly reduces the risk of low bone mineral density by 69% compared to non-users. This suggests that hormone therapy could be an effective way to prevent bone loss and lower fracture risks in women after menopause.
A study presented at ENDO 2026 found semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared to other anti-obesity medications. The results suggest that semaglutide may have beneficial effects on bone health in people with type 2 diabetes.
A study found that nearly 4 in 10 patients stopped GLP-1 medication within the first year and nearly two-thirds restarted therapy within two years. The researchers also identified sociodemographic, clinical, and provider-level predictors of discontinuation, including Medicaid or Medicare status, Black patients, and side effects.
The study found a significant increase in type 1 diabetes cases among Hispanic/Latino adolescents in Puerto Rico, from 10.1 per 100,000 in 2009 to 24.1 in 2021, with an average annual increase of 4.1%. This trend has important implications for patient care and public health.
A study presented at the Endocrine Society's annual meeting found that exposure to the plasticizer DEHP in early development can lead to increased anxiety-like behavior in adult male rats. The research suggests that humans exposed to endocrine disruptors before and shortly after birth may experience long-lasting behavioral changes.
A new AI model analyzed 30 years of EHR data to identify patients with primary aldosteronism, a common cause of high blood pressure. The model correctly flagged over 90% of cases while missing fewer than 10%, suggesting it could improve screening for this condition.
A study of 336 mother-infant pairs found that breast milk and infant urine contained over 50 different chemicals, including BPA and phthalates, which can interfere with hormones during baby's development. These chemicals were detected in breast milk and urine up to 6 months after birth.
Researchers at Sanford Burnham Prebys Medical Discovery Institute found that enhancing protein-folding processes can help prevent harm to insulin-producing cells. The study revealed the importance of a chaperone protein called binding immunoglobulin protein and its cochaperone protein p58 IPK in maintaining proper proinsulin folding.
A study led by Raül Andero at the Universitat Autònoma de Barcelona found that the ratio of progesterone to estradiol hormones in saliva can predict memory performance, including fear extinction in both mice and humans. This hormonal balance may help identify optimal times for learning and memory tasks.
Prediagnostic statin use showed no association with higher survival rates, but postdiagnostic use was linked to lower all-cause and breast cancer-specific mortality among hormone receptor-positive subtypes. Statin therapy may improve survival of these patient groups.
A new study by UNIGE and SCAHT reveals that cannabis use is associated with an increase in testosterone levels, particularly in the testes. However, this increase does not appear to have a direct link to fertility, and further research is needed to determine potential long-term effects.
Researchers found that the gut responds to protein deficiency by activating a fast neural circuit and a slower hormonal signal, which selectively changes dietary priorities. The study reveals a previously unknown gut-brain signaling system that rapidly alters feeding behavior in animals.
The Endocrine Society and Keystone Symposia will host their first joint conference in October to explore discovery in cancer, diabetes, and cardiometabolic disease. The conference series aims to strengthen the exchange of scientific knowledge through coordinated programming, facilitating discovery and collaboration among researchers.
Polyendocrine Ovarian Syndrome (PMOS) impacts 13% of women, causing hormonal imbalance, insulin resistance, and chronic pain. Lifestyle interventions, particularly diet and exercise, show benefits for physical and mental health outcomes.
The 28th European Congress of Endocrinology (ECE) 2026 brought together over 4,500 delegates from 111 countries to experience the latest endocrine research and developments. The Congress celebrated the Society's 20th Anniversary and featured groundbreaking studies on hormone disruption, bone development, insulin resistance, and polycys...
Research finds estrogen plays a powerful role in regulating liver health, inflammation control, and energy processing, which become disrupted when levels decline. Restoring estrogen reverses many effects, suggesting targeting inflammatory pathways may prevent heart disease in women after menopause.
Research found that girls born to mothers with higher insulin resistance during pregnancy are more likely to have more abdominal fat at age 7. Maternal insulin resistance was not associated with body fat in boys, suggesting girls may be more susceptible to the mother's insulin resistance during late pregnancy.
A randomized clinical trial found that testosterone treatment significantly improved sexual activity, sexual desire, and quality of life scores in men after prostate cancer surgery. The treatment also improved body composition and aerobic performance without increasing the risk of biochemical recurrence.
Research suggests that exposure to environmental pollutants in early life can negatively affect bone development. A study of 88 healthy infants found associations between certain endocrine-disrupting chemicals and lower bone mineral density, emphasizing the importance of protecting vulnerable windows during pregnancy and after birth.
Research in male sheep fetuses finds that excessive prenatal progesterone exposure alters the SRD5A1 gene, crucial for processing sex hormones in brain development. The study highlights the importance of hormones in fetal development and potential links to adult disease.
A large-scale Nordic study found a link between PCOS and heart disease, with women at increased risk even in normal weight. The study also highlighted the importance of regular medical screenings for women with PCOS.
The ECE 2026 brings together researchers and clinicians to share the latest endocrine research and developments. Key sessions include Plenaries, Symposia, Awards, Meet the Experts, Debates, and Oral Communications.
A new study has found that individuals with insulin-requiring type 1 and type 2 diabetes have a significantly higher risk of developing dementia compared to those without diabetes. The study, which examined over 1.3 million adults in South Korea, suggests that dementia risk is not the same for all types of diabetes.
Researchers developed an AI-driven wearable skin sensor patch to track reproductive hormones and detect hidden endocrine dysfunction, which can improve conception. The study found that men with normal testosterone levels may still have disrupted hormone rhythms associated with reproductive dysfunction.
A NIH-funded study discovered that testosterone may play a key role in limiting brain tumor growth in men by suppressing inflammation and stress hormone production. Analysis of over 1,300 men with glioblastoma found that supplemental testosterone was significantly associated with improved survival rates.
Italian researchers Anna Pilatone and Gabriella Milan won the Endocrine Society's 2026 Endocrine Images Art Competition with their image of a pre-adipocyte cell, highlighting the complexity of adipose tissue in obesity. The winning entry will be displayed at ENDO 2026 and featured in Endocrine News magazine.
A review from Florida Atlantic University links obesity to Alzheimer's disease through disruptions in metabolism, highlighting the importance of mitochondrial function and gut-brain axis balance. Early detection and whole-body prevention may become possible through monitoring metabolic health.
A study published in Cells suggests that declining estrogen levels alter epigenetics, which may explain the rise in heart disease risk after menopause. The researchers identify a potential link between estrogen loss and changes in cardiovascular health.
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
An international analysis found that intrauterine administration of human chorionic gonadotropin (hCG) before embryo transfer does not increase pregnancy or live birth rates. The study urges patients and clinicians to rethink the commonly offered IVF add-on, citing concerns about unreliable trial data.
A massive genetic study has uncovered six new genes linked to pregnancy sickness, hyperemesis gravidarum (HG), in over 10,000 women. The findings point to biological mechanisms behind HG and potential new treatment pathways, with several medications identified as potential targets.
A hormone called FGF21 reverses obesity in mice by signaling to the hindbrain, a region targeted by GLP-1 drugs. This finding provides insight into the naturally occurring hormone's benefits for weight loss and MASH treatment.
A new study reveals that biochar nanoparticles directly enter plant tissues and enhance flowering by reshaping carbon allocation and regulating key genes. This discovery provides a new explanation for how biochar improves crop performance beyond its effects on soil fertility.
A new study led by Krista Varady found that intermittent fasting reduces testosterone levels and improves female hormone levels in women with PCOS. The study tested time-restricted eating and calorie counting methods, showing that intermittent fasting had additional benefits over calorie counting.
A study by Florida Atlantic University researchers has uncovered the impact of stress on wild songbirds, finding that even mild challenges can alter the gut microbiome, leading to changes in health indicators such as beak color and stress hormone levels.
A study published in Science reveals that microglia and the protein RANK are involved in regulating the hypothalamic-pituitary-gonadal axis, which controls fertility. The research found that suppressing RANK expression led to distorted reproductive function, including reduced sex hormones and hypogonadism.
A study published in American Journal of Physiology-Endocrinology and Metabolism found that low testosterone and high fructose intake synergistically contribute to liver damage in mice. The researchers discovered that changes in gut microbiota led to increased levels of pyruvate, which promotes fat accumulation in the liver.
Pituitary neuroendocrine tumors (PitNETs) are associated with cognitive decline, which may be linked to hormonal dysregulation and gut microbiota alterations. Surgical intervention improves cognitive function, suggesting a potential endocrine mechanism underlying cognitive dysfunction and recovery.