Articles tagged with Hormones
Researchers at Mass General Brigham identified seven metabolites in the blood associated with excessive daytime sleepiness (EDS), a condition linked to increased risk of cardiovascular disease, obesity, and diabetes. The study also found that dietary changes or supplements may help reduce EDS risk.
A study by Steve Chang explores how oxytocin influences brain activity to shape social behavior in rhesus monkeys. The researchers found that oxytocin increased activity in the basolateral amygdala and anterior cingulate cortex when monkeys were socially motivated, maintaining beneficial decisions and social task behavior.
Researchers at Cornell University developed an implant system that can treat Type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, enabling long-term treatment for chronic diseases. The system could also potentially provide treatment for other autoimmune diseases.
A new analysis published in The Journal of Clinical Investigation reveals how leptin affects the brain and its potential use in future therapeutics for type 1 diabetes. Leptin helps regulate appetite and body weight, and insufficient levels lead the brain to activate circuits that mobilize energy sources, including glucose and ketones.
Dr. David Rubinow's research reveals that susceptible women respond differently to normal hormonal fluctuations, leading to breakthrough treatment approaches and FDA-approved medication for postpartum depression. His work validates the experiences of millions of women whose hormone-related mood symptoms were previously misunderstood.
Despite supply shortages and insurance coverage obstacles, patients taking GLP-1 medications achieve clinically significant weight loss when paired with intensive lifestyle interventions. The study found that consistent medication courses combined with lifestyle changes and support remain the most effective weight-loss program option.
A new study found that anti-obesity medications can normalize testosterone levels in men with obesity or type 2 diabetes. This positive effect on reproductive health was observed after a 10% weight loss, with total and free testosterone levels increasing by 24%.
A study presented at the Endocrine Society's annual meeting found that socially isolated older adults are 34% more likely to have diabetes and 75% more likely to have poor blood sugar control. Social isolation is being recognized as a critical social determinant of health, highlighting its importance in caring for older patients.
An animal study found that early-life exposure to endocrine-disrupting chemicals can alter the brain's pathways controlling reward preference and eating behavior. Male rats showed a temporary preference for sugary solutions, while female rats gained weight after preferring high-fat food.
A study found that consuming aspartame, sucralose, glycyrrhizin and added sugars may increase the risk of early puberty in children, especially those with genetic traits. This association was strongest for central precocious puberty, a condition linked to emotional distress and metabolic disorders.
A new study found that intermittent energy restriction significantly improved fasting blood glucose and triglycerides, while also increasing insulin sensitivity. The IER group showed the greatest advantages in reducing these markers compared to time-restricted eating and continuous energy restriction groups.
A new study presents preliminary data suggesting that grandparents' exposure to endocrine-disrupting chemicals may impact the age when girls get their first period. The research found that certain chemicals in both mothers and fathers were linked to earlier puberty, with stronger effects seen in granddaughters.
A real-world study of 120 postmenopausal women found that using tirzepatide and menopause hormone therapy simultaneously led to superior total body weight loss percentage compared to using tirzepatide alone. This combined treatment also resulted in a higher percentage of participants achieving at least 20% weight loss.
A long-term study of healthy men found that minimally elevated blood sugar levels can lead to declines in sperm movement and erectile function. The study suggests that lifestyle choices and medical interventions can help preserve or revive reproductive health in aging men.
Research suggests that thyroid hormone treatment can improve gut health in individuals with hypothyroidism, particularly those with autoimmune thyroiditis. The study found a higher prevalence of SIBO in people with hypothyroidism compared to controls, which was mitigated by thyroid medication.
A study by The Endocrine Society reveals that children with growth hormone deficiency experience improved overall health and coping mechanisms when their caregivers report reduced stress, anxiety, and depression. Conversely, caregivers' emotional stability is associated with better outcomes for the child.
Researchers found that disabling mERα signaling in osteoblast lineage cells reduced cortical bone mass and density, leading to weaker bones. This pathway is essential for maintaining bone strength and density, especially in females.
A new technique allows scientists to inject molecules into coral tissues, revealing thyroxine's positive effect on calcification. The study raises questions about the evolution of animal physiology and how corals utilize thyroxine in their natural habitat.
Researchers found that rats with shorter second digits exhibit stronger sexual behavior, including a preference for female scent and frequent ejaculations. This study reveals the impact of fetal hormone exposure on brain development and highlights the link between body and mind.
Elevated cortisol levels in preterm fetuses disrupt normal heart development, potentially leading to increased cardiovascular disease risk. Cortisol exposure accelerates heart development in ways that may not be beneficial, ultimately compromising heart health.
A multi-center clinical trial found that Duavee, a menopause drug, significantly reduced cell growth in breast tissue and was well-tolerated by participants. The study suggests that Duavee may offer a promising alternative for women at elevated risk of invasive breast cancer due to personal or family history.
Researchers at the University of Oklahoma discovered that FGF21 can reverse fatty liver disease in mice by sending signals to both the brain and liver. The study provides valuable insight into the mechanism of action of FGF21, a target for a new class of highly anticipated drugs.
A large-scale study published in eClinicalMedicine found that transmasculine and gender-diverse individuals who use testosterone for an average of five years do not have an increased risk of gynecological cancer. The research, which followed 1955 participants, suggests that hormone therapy may be safe for this group.
The EndoCompass project aims to guide future studies and funding programs with a research roadmap for better hormone health in Europe. Manuel Heitor will share his perspective on the future of research in Europe, emphasizing the need for greater investment and coordination.
A new study has discovered a link between delayed puberty and an increased risk of developing type 2 diabetes in boys. According to the research, adolescent boys who experience delayed puberty are 37% more likely to develop type 2 diabetes in early adulthood, regardless of their weight or socio-economic status.
Researchers developed tiny human ovary organoids using stem cells to understand gonad development and disease. The models replicate key aspects of ovarian follicles, offering a powerful platform for studying gene function in a controlled environment.
Women who experience menopause before age 50 are at higher risk of developing fatty liver disease and its related metabolic risk factors. The study found that early menopause is associated with increased risks of pre-diabetes, obesity, hypertension, and dyslipidemia.
Research reveals individuals taking oral steroids for over 3 months are 6 times more likely to be diagnosed with adrenal insufficiency than those treated with non-steroidal anti-inflammatory drugs. Long-term users of inhaled steroids also face increased risk without hospitalisations.
Research suggests that antibiotics taken during infancy, especially in the first three months, may lead to earlier onset of puberty in girls. The study, which analyzed data on over 322,000 children in South Korea, found a significant association between early antibiotic exposure and increased risk of central precocious puberty.
A meta-analysis of 21 studies involving over 178,000 women found that those with infertility history have a 14% increased risk of heart or blood vessel conditions, as well as higher risks of heart disease and stroke. Younger women and those undergoing fertility treatments are at greater risk.
Research shows that low phosphate levels in blood are associated with reduced sperm motility and poor semen quality. The findings suggest a potential link between phosphate and male fertility, highlighting the importance of understanding biological factors involved in reproductive health.
The inaugural Joint Congress brings together paediatric and adult endocrine specialists to learn from each other, collaborate, and celebrate endocrinology. Over 7,500 delegates from 100 countries attend the event to experience the latest research and developments.
Research found that early-life growth plays a significant role in determining final adult height, accounting for about 67% of the variation. Childhood growth also accounted for a substantial proportion of the difference in adult height.
Research finds high levels of phthalates in mothers' urine associated with shorter anogenital distances in 3-year-old boys and girls, a marker of reproductive health and hormone disruption. The study emphasizes the need for preventive measures to protect vulnerable groups from endocrine-disrupting chemicals.
Research found that boys born to mothers with polycystic ovary syndrome (PCOS) or higher testosterone levels during pregnancy are less physically active at age 7. Girls exposed to similar levels of testosterone had lower muscle strength, highlighting the role of maternal testosterone and PCOS in future development.
The event aims to create a positive scientific and policy legacy from the Congress in Denmark, Europe, and internationally. The conference will focus on key research presented at the Joint Congress and future priorities from the EndoCompass Research Roadmap.
Researchers discovered neuroestrogen's role in regulating food intake and hunger. Neuroestrogen enhances the brain's responsiveness to leptin, a hormone that helps regulate hunger.
The European Society of Endocrinology and the European Hormone and Metabolism Foundation launch a global campaign to raise awareness about hormone balance and its impact on chronic diseases. Small steps can make a big difference in improving hormone health.
Researchers discovered a mechanism that harnesses immune cells to produce opioids, potentially alleviating chronic pain. Estrogen and progesterone drive this process, which could lead to more effective treatments for women experiencing pain after menopause.
Hormonal contraceptives initiated immediately after childbirth may increase the risk of developing depression in new mothers. Researchers found that combined oral contraceptives were associated with a higher risk of depression when started earlier postpartum.
A recent study published in Science Advances found that oral contraceptive use in women is associated with changes in steroid hormone levels, while smoking in men is linked to altered levels of nearly every steroid hormone measured. The study also discovered a link between decreased androgens and various diseases in aging men.
A recent study found that everyday physical activity does not slow bone loss during menopause, contrary to previous studies suggesting exercise can mitigate age-related bone weakening. Despite this, researchers believe more targeted exercise may help slow hormonal bone loss.
Researchers discovered Lepr neurons in the dorsomedial hypothalamus communicate using glutamate and GABA to regulate metabolism, body weight, and energy use. The study sheds light on fundamental neuronal interplay influencing metabolic adjustments.
The University of Turku researchers have developed a new method to create more accurate sensors for detecting subtle changes in the body, such as hormone fluctuations. By purifying and separating single-wall carbon nanotubes, they achieved precise control over their properties and identified their electrochemical characteristics.
Media professionals can register for ENDO 2025 to discuss groundbreaking research on obesity, diabetes, and more with world-renowned experts. The event features nearly 2,500 abstracts and over 200 sessions, offering a premier global conference in endocrinology research and clinical care.
A recent study by Murdoch University reveals that moderate-intensity exercise significantly influences appetite-related hormones and perceptions in males with obesity. The study confirms the benefits of incorporating regular exercise into daily routines for weight management and overall health improvement.
Scientists have created a new epigenetic tool that can estimate months of androgen exposure in animals, such as mice and sheep. The Androgen Clock is a linear model that uses specific DNA regions to measure androgen exposure over time.
Research revealed a single gene drives the production of a super enzyme in male ruff's blood, which rapidly breaks down testosterone. This process regulates sex hormones and influences mating behaviors in non-aggressive males.
Research led by University of Arizona researchers found that PTSD and anxiety are associated with lower levels of anti-Müllerian hormone, a marker of ovarian reserve, among women firefighters. The study suggests that mental health conditions can have a negative impact on reproductive health.
A new study from Harvard T.H. Chan School of Public Health and colleagues reveals that less than 0.1% of privately insured US adolescents receive puberty blockers or gender-affirming hormones. No TGD patients under age 12 were prescribed hormone treatment, indicating low access to care among this population.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Christopher Kassotis, a Wayne State University assistant professor of pharmacology, has been recognized for his outstanding work on endocrine disruption research. His research focuses on identifying and characterizing environmental chemicals that impact human and animal health.
A new animal study published in the Journal of the Endocrine Society found that early life exposure to polychlorinated biphenyls (PCBs) may lead to behavioral problems in rats. PCBs, which have been banned for decades, can reprogram a developing neuroendocrine system and cause developmental and hormonal changes.
The University of Cincinnati College of Medicine has launched a styrofoam recycling project to divert over 900 pounds of EPS waste from landfills each month. The program aims to reuse existing styrofoam materials, reducing the need for styrene and minimizing environmental impact.
Dr. Seymour Reichlin's centennial celebration highlights his ongoing scientific impact, with recent collaborations yielding new insights into hormone therapies for cognitive enhancement and emotional homeostasis. His work has established neuroendocrinology as a distinct field, bridging neuroscience, endocrinology, and clinical medicine.
Long-term hormone therapy in transgender individuals leads to significant changes in body composition and risk factors for cardiovascular disease. Transgender men experience increased muscle volume and abdominal fat, while women's muscle mass decreases, according to a new study published in the Journal of Internal Medicine.
Researchers identified a novel role for the locus coeruleus in facilitating transition between NREM and REM sleep states while maintaining unconscious vigilance. Stress disrupts its functions, negatively impacting sleep quality. The study provides crucial insights into sleep disorders and could lead to improved treatments.
A team of scientists has pinpointed a critical neural circuit for female sexual rejection, revealing how the brain integrates signals to shape behavior. The ventromedial hypothalamus, specifically progesterone-sensitive neurons in the anterior VMH, play a crucial role in determining whether a female accepts or rejects mating attempts.
A nationwide study found that Swedish young men with delayed puberty are more likely to use healthcare services later in life. They were also more likely to be admitted to hospital and prescribed medications, indicating potential long-term health consequences.
Dr. Philip Gold's landmark paper reveals depression's full-body impact, documenting structural brain changes and disruptions in hormone systems. His analysis highlights interconnected mechanisms underlying the disease, opening new therapeutic possibilities for innovative treatments targeting neuroendocrine dysfunction.