Researchers at The University of Osaka discovered a key neuroendocrine pathway underlying the seasonal shift in insect reproduction. The brain peptide corazonin plays a suppressive role in reproduction under short-day conditions, allowing insects to prepare for winter.
A recent study utilizes AI to optimize catalyst design and synthesis, predicting structure-property relationships and minimizing resource-intensive calculations. The research also explores the integration of automated synthesis, characterization, and optimization in closed-loop systems.
The LIGO-Virgo-KAGRA Collaboration detected the merger of two massive black holes, producing a final black hole over 225 times the mass of our Sun. The signal challenges current astrophysical models and requires the use of theoretical models to interpret its complex dynamics.
The journal is seeking submissions on brain-computer interface technology, which can assist diagnosis and treatment of neurological diseases, promote mental illness research, and enhance rehabilitation treatment. The deadline for manuscript submissions is December 30, 2025.
The 4th LabMed Discovery Youth Scholars Forum will provide a platform for young researchers to share cutting-edge scientific advancements. The event will focus on advances in colorectal cancer treatment and cardiovascular research.
Researchers from Tsinghua University Press have discovered three novel bianthrones with significant cytotoxic activity against tumor cell lines. The compounds were isolated using HSQC-based DeepSAT technology, and their mechanisms of action were investigated through network pharmacology and molecular docking.
The guideline suggests screening women of reproductive age with diabetes for intent to conceive at every reproductive, diabetes, and primary care visit to ensure they receive appropriate preconception care. Women with diabetes who become pregnant are at risk for adverse pregnancy outcomes, such as miscarriages or birth defects, which c...
Researchers at The University of Osaka develop an AI-powered framework to measure micro-scale occupancy in open-plan offices, providing detailed data for evidence-based design decisions. The system uses computer vision and 3D pose estimation to analyze video footage and track individuals within predefined zones.
An animal study found that early-life exposure to endocrine-disrupting chemicals can alter the brain's pathways controlling reward preference and eating behavior. Male rats showed a temporary preference for sugary solutions, while female rats gained weight after preferring high-fat food.
Researchers developed a π-electron delocalization-based strategy to optimize aqueous zinc-ion battery performance. A hydrophilic–hydrophobic interfacial layer (HHIL) on the Zn anode surface enhanced stability and electrochemical reversibility, regulating Zn deposition and suppressing parasitic reactions.
Researchers designed model cracking catalysts with controlled interfacial channel connectivity, enabling exploration of structure-diffusion-reaction relationships. Advanced characterization techniques revealed a pronounced 'funnel effect' from mesopores, accelerating interfacial diffusion and enhancing catalytic efficiency.
Researchers have discovered a new treatment approach for two leading causes of blindness worldwide, using a Singapore-developed cancer drug. The study found that intravenous delivery showed an 86% greater reduction in abnormal blood vessel leakage compared to traditional eye injections.
A new study found that intermittent energy restriction significantly improved fasting blood glucose and triglycerides, while also increasing insulin sensitivity. The IER group showed the greatest advantages in reducing these markers compared to time-restricted eating and continuous energy restriction groups.
A KAIST team engineered a microbial strain capable of producing lutein at industrially relevant levels. They developed an electron channeling system to overcome previous limitations, achieving record-breaking 1.78 g/L of lutein production in fed-batch fermentation.
Researchers at The Hebrew University of Jerusalem have found that mesenchymal stem cell secretions can help protect mammary cells from stress while increasing milk fat production. This breakthrough could lead to healthier cows and richer, creamier milk without the need for additives or heavy processing.
A study presented at the Endocrine Society's annual meeting found that socially isolated older adults are 34% more likely to have diabetes and 75% more likely to have poor blood sugar control. Social isolation is being recognized as a critical social determinant of health, highlighting its importance in caring for older patients.
A rare ichthyosaur fossil from the Late Triassic period was discovered in western Japan, providing significant insights into ichthyosaur evolution. The fossil's unique characteristics suggest a high swimming ability, offering valuable clues for understanding this marine-adapted reptile.
Scientists at University of South Australia developed a long-acting injectable formulation that delivers levodopa and carbidopa over a week, reducing the need for multiple daily tablets. The biodegradable formulation improves treatment outcomes and patient compliance, offering a potential game-changer for Parkinson's care.
A study found that consuming aspartame, sucralose, glycyrrhizin and added sugars may increase the risk of early puberty in children, especially those with genetic traits. This association was strongest for central precocious puberty, a condition linked to emotional distress and metabolic disorders.
A randomized, placebo-controlled study shows that acupuncture can safely reduce methadone requirements and counteract opioid-induced immune and gut disturbances. Acupuncture was found to lower methadone doses by 20% in 84% of patients, while boosting antiviral gene activity and restoring bile acid balance.
Cancer deaths linked to obesity have increased sharply in the US, especially among women and older adults, with sharp regional disparities. The study highlights the need for targeted public health strategies to address this growing public health crisis.
The LIGO-Virgo-KAGRA Collaboration has detected the merger of two massive black holes, producing a final black hole approximately 225 times the mass of our Sun. The signal presents a challenge to current astrophysical models and requires advanced theoretical tools to interpret.
This study reveals the critical roles of Rho GTPases Cdc42 and RacA in Aspergillus flavus growth, development, and metabolism. The proteins regulate aflatoxin synthesis, pathogenicity, and oxidative balance by controlling morphogenesis, energy metabolism, and fatty acid β-oxidation.
A new study presents preliminary data suggesting that grandparents' exposure to endocrine-disrupting chemicals may impact the age when girls get their first period. The research found that certain chemicals in both mothers and fathers were linked to earlier puberty, with stronger effects seen in granddaughters.
Researchers found that floor video projection with simple and interactive pacer methods improved running patterns and performance in students with neurodevelopmental disorders. The study suggests personalized support based on individual cognitive traits is crucial for enjoyable and safe physical activities.
Researchers developed a highly efficient and stable chainmail catalyst for acidic hydrogen evolution, utilizing cobalt-nickel nano-alloy encapsulated in graphene. The confinement of asymmetric π electronic states on the graphene surface enhances catalytic activity and durability.
Researchers at Kyoto University have characterized quantum advantage by proving an equivalence between its existence and the security of certain cryptographic primitives. This breakthrough implies that when quantum advantage does not exist, many conventional cryptographic primitives are broken, including post-quantum ones.
The study introduces aspartame as an electrolyte additive to improve zinc anode performance, resulting in enhanced corrosion resistance and cycling stability. The self-healing ZnO-based SEI film enables long-cycling and wide-temperature operation of aqueous zinc-ion batteries.
A novel AI-powered application has been developed to diagnose endocrine cancers with speed and accuracy, leveraging advanced deep learning architectures. The tool analyzes diverse medical data, including imaging scans and histopathology images, and demonstrated exceptional diagnostic accuracy in certain validation datasets.
A study of over 7,600 Brazilian women found that early menarche increases risk for metabolic and heart problems, while late menarche may protect against obesity but increase certain heart issues. Understanding age at first period can help doctors identify high-risk patients and guide personalized screening and prevention efforts.