Articles tagged with Metabolic Pathways
A new study published in BMC Systems Biology uses computational method corsoFBA to model cellular metabolism and discover how organisms adapt to changing environments. The researchers, led by Amina Qutub, aim to develop new treatments for diseases such as stroke and cancer.
A study in the Journal of Clinical Investigation found that UCP2 induces fatty acid synthesis, activating inflammatory pathways in patients with sepsis. Lack of UCP2 improved survival in a mouse model of sepsis, suggesting UCP2 as a potential therapeutic target.
Researchers at JBEI have developed a technique called targeted proteomics that enables the rapid identification and quantification of specific proteins in cells or microbes. This technique can help identify bottlenecks in metabolic pathways, leading to improved efficiency and productivity in biofuel and therapeutic drug production.
Researchers have discovered that during early stages of heart failure, the heart uses too much fatty acid and not enough carbohydrate; later on, it doesn't use enough fat. This new knowledge can lead to better treatments, but the existing drugs don't remedy the inefficiency.