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Gene variant increases risk of cardiac arrhythmia for African-Americans

A study led by Mark T. Keating found that 13.2% of African-Americans carry an altered form of the SCN5A gene, linked to prolonged contraction of heart muscle cells and arrhythmia risk. The variant can be detected through simple tests, allowing for preventive measures such as avoiding certain medications and monitoring potassium levels.

SourceHoward Hughes Medical Institute·JournalScience·DateAug 22, 2002

Molecular clues to an inherited epilepsy

Researchers identified genetic mutations associated with inherited epilepsy that perturb brain cell electrical properties. These findings support a plausible mechanism for the disorder and suggest potential targets for anticonvulsant drugs.

SourceVanderbilt University Medical Center·JournalNeuron·DateJun 12, 2002
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Medical Alchemy Could Cut Heart Failure Deaths University Of Maryland Scientists Turn Sodium Channels Into Calcium Channels

University of Maryland scientists have discovered a way to transform sodium channels into calcium channels, which could lead to the development of new treatments for heart failure and various neurological conditions. This breakthrough, reported in the journal Science, opens up novel targets for drug discovery and molecular medicine.

SourceUniversity of Maryland School of Medicine·JournalScience·DateFeb 13, 1998

Cell-Membrane Proteins Appear To Play Key Role In Squid's Swiftness

A study comparing cephalopod and gastropod nervous systems reveals that cephalopods have more rapid-acting electrical firing systems, enabling their high-speed swimming behavior. The key element of the findings involves sodium channels in motor neurons used for jet-propelled swimming.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·DateApr 3, 1997
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