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What's your poison? Scrupulous scorpions tailor venom to target

Researchers found that scorpions adapt their stingers and venom use to minimize costs, with strategies including avoiding venom, using claws or pedipalps, and adjusting sting volume and composition. Scorpions can also tailor venom to a target through on-the-fly adjustments and over weeks of exposure.

SourceFrontiers·JournalFrontiers in Ecology and Evolution·DateJun 10, 2019

Spider venom is a dangerous cocktail

Researchers at the University of Bern studied spider venom from the Cupiennius salei species, discovering a dual prey-inactivation strategy involving neurotoxins and metabolic pathways. This complex effect mechanism attacks an organism's muscles, nervous system, and internal homeostasis, causing paralysis, pain, and inflammation.

SourceUniversity of Bern·JournalToxins·DateMay 2, 2019

UTA biologist shows new insights into chromosome evolution, venom regulation in snakes

Researchers have made significant breakthroughs in understanding snake genomes, including the evolution of venom genes, dosage compensation mechanisms, and sex determination systems. The study provides a comprehensive genomic context for these complex biological processes, offering new insights into the unique adaptations of snakes.

SourceUniversity of Texas at Arlington·JournalGenome Research·DateMar 29, 2019

Nanoparticles to treat snakebites

Researchers developed nanoparticles that bind to venom toxins, mitigating local damage and systemic distribution of toxins in mouse experiments. The treatment has the potential to be administered subcutaneously after a bite, offering a new approach to treating snakebites in rural settings.

SourcePLOS·JournalPLOS Neglected Tropical Diseases·DateOct 4, 2018

Ants surrender their venomous secrets

Researchers analyzed ant venom from a tropical species and identified over 2,800 venom peptides, including 37 full-length peptide precursors called myrmicitoxins. The peptides showed sequence similarities with those produced by other insects, suggesting they evolved from ancestral genes.

SourceAmerican Chemical Society·JournalJournal of Proteome Research·DateSep 12, 2018

When it rains, snake bites soar

A new study found that rainy years lead to a 3.9% spike in snake bites across California's 58 counties, contradicting the notion that drought increases encounters with venomous reptiles. The researchers suspect that rodents, which thrive in rainy conditions, may be the primary driver of this unexpected trend.

SourceUniversity of Colorado at Boulder·JournalClinical Toxicology·DateSep 5, 2018

Scorpion venom component can reduce severity of rheumatoid arthritis

Researchers at Baylor College of Medicine discovered that a scorpion venom component, iberiotoxin, can specifically block the potassium channel in fibroblast-like synoviocytes, reducing rheumatoid arthritis severity. Treatment with iberiotoxin reversed joint damage and inflammation in rat models without inducing side effects.

SourceBaylor College of Medicine·JournalJournal of Pharmacology and Experimental Therapeutics·DateFeb 26, 2018

How centipedes slay giant prey

A golden head centipede can subdue a caged mouse in under 30 seconds by injecting an estimated 30 μl of crude venom containing SsTx. The peptide toxin strongly inhibits KCNQ4 channels, controlling pulmonary vascular tone and arterial tension, leading to vasoconstriction and cardiovascular effects.

SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateJan 22, 2018

Why tiger snakes are on a winner

Researchers have discovered that Australian tiger snake venom is highly conserved across species, making the corresponding antivenom effective against many other snake bites. This finding has significant human medical benefits and upends a long-held theory on venom evolution.

SourceUniversity of Queensland·JournalComparative Biochemistry and Physiology·DateAug 21, 2017

Venom becomes more potent as brown snakes age

Research led by University of Queensland scientist Associate Professor Bryan Fry reveals that brown snake venom attacks the nervous system in young snakes and circulatory system in older ones. This transformation allows the venom to become more potent and deadly, causing internal bleeding and death in humans.

SourceUniversity of Queensland·JournalComparative Biochemistry and Physiology·DateMay 16, 2017

Bee alert but not alarmed

A national analysis of 13 years' data reveals that Australia's venomous creatures pose a significant public health threat. Bees and wasps are responsible for the most hospital admissions, followed by spider bites and snake bites, with anaphylactic shock being a major contributor to fatalities.

SourceUniversity of Melbourne·JournalInternal Medicine Journal·DateJan 17, 2017