Articles tagged with Vitamin E
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Researchers discovered vitamin E can alleviate symptoms of nonalcoholic steatohepatitis (NASH) in mice, a common complication of obesity. The study suggests that supplementation with vitamin E may have significant public health benefits.
A specific form of vitamin E supplement can accelerate heart health benefits after quitting smoking. Smokers who took the gamma-tocopherol form showed a 19% greater drop in cardiovascular disease risk and improved vascular function.
Despite concerns over high vitamin E intake, a new review concludes that the body can eliminate excess levels of the vitamin, making it impossible to take a harmful amount. Vitamin E is essential for proper organ function and has antioxidant properties.
Researchers at Ohio State University identified a unique mechanism by which vitamin E inhibits the activation of an enzyme called Akt, leading to tumor cell death in prostate cancer cells. The gamma form of tocopherol was found to be the most potent anti-cancer form of vitamin E.
A recent study published in the Journal of the National Cancer Institute found that high vitamin E intake from diet or supplements is associated with lower liver cancer risk. The analysis included 132,837 individuals and showed a clear inverse dose-response relation between vitamin E intake and liver cancer risk.
A large cohort study found that high vitamin E intake from diet or supplements is associated with a lower risk of liver cancer. The study included over 132,000 individuals and analyzed data from two population-based cohort studies conducted in China.
Researchers found that gamma and delta-tocopherols in vegetable oils prevent cancer formation and growth in animal models. Alpha-tocopherol supplements, however, showed no such benefit in preventing these types of cancer.
Vitamin E helps repair tears in plasma membranes that protect cells from outside forces. Daily consumption of vitamin E is crucial to maintain healthy muscles and prevent conditions like muscular dystrophy and diabetes.
A study of over 35,000 men found that daily vitamin E supplementation was associated with a significantly increased risk of developing prostate cancer. The researchers observed a 17% higher rate of prostate cancer detection in the vitamin E group compared to the placebo group.
A large national study has found that men taking a daily vitamin E supplement face an increased risk of prostate cancer. The Selenium and Vitamin E Cancer Prevention Trial (SELECT) tracked over 35,000 men and found a 17 percent higher incidence of prostate cancer in those taking the supplement.
A new NIH-funded study shows that taking high doses of vitamin E daily increases the risk of developing prostate cancer. Compared to a placebo group, men who took vitamin E supplements had 11 more cases of prostate cancer per 1,000 men over a seven-year period.
Researchers found that alpha-tocotrienol triggers production of a protein in the brain that clears toxins from nerve cells after a stroke. The study also identified two other mechanisms: blocking an enzyme's release of toxic fatty acids and inhibiting neuron death gene activity.
A new study published in JAMA found that neither vitamin E nor the diabetes drug metformin successfully reduced liver enzymes in children and teens with nonalcoholic fatty liver disease. However, a biopsy of the liver showed improvement in injury pattern with vitamin E therapy in patients with severe fatty liver disease. The study high...
A study funded by NIH found that vitamin E improved the most severe form of fatty liver disease in children, reversing NASH in at least half. The treatment showed significant reductions in liver cell death and improvements in liver enzyme levels.
A randomized controlled trial found that vitamin E and metformin did not demonstrate significant efficacy in reducing liver disease severity or improving insulin resistance in children. The study suggests that lifestyle modification is crucial, while further research into non-invasive markers is warranted.
A study by Dr. Harri Hemila and Professor Jaakko Kaprio found that vitamin E supplementation had varying effects on pneumonia risk depending on smoking habits and exercise levels. Among nonsmokers who exercised regularly, vitamin E decreased pneumonia risk by 69%. However, in smokers and non-exercisers, it increased risk by 79%.
A study by the University of Helsinki found that vitamin E supplementation reduces mortality by 24% in participants aged 71 or older. However, it had no effect on life expectancy for those between 65 and 70 years old with high dietary vitamin C intake.
A study of over 11,500 male physicians found that long-term use of vitamins E and C had no significant impact on the development or extraction of age-related cataracts. The researchers concluded that high-dose supplementation with these vitamins has little effect on rates of cataract diagnosis and extraction.
Children with third-degree burns lose almost half of their stored vitamin E in just three weeks, despite receiving high-calorie diets. This rapid depletion may lead to health complications, including peripheral neuropathy.
Research finds pentoxifylline improves NASH, reducing fat and inflammation; vitamin E also shows promise in improving liver histology independently of insulin resistance. Studies suggest new treatment options for overweight individuals with liver disease.
Researchers at Queensland University of Technology have identified a specific vitamin E constituent that can inhibit the growth of prostate tumors. The treatment, tocotrienol (T3), has shown promise in animal trials, with complete inhibition of tumor formation in over 70% of mice implanted with prostate cancer cells.
A study published by the American Thoracic Society found that long-term vitamin E supplementation may decrease the risk of chronic obstructive pulmonary disease (COPD) by about 10% in both smokers and non-smokers. Vitamin E may protect lung tissue from damage caused by free radicals, according to researchers.
A new study published in the New England Journal of Medicine found that vitamin E improved features of nonalcoholic steatohepatitis (NASH), an obesity-related chronic liver disease. After 96 weeks of treatment, 43% of those treated with vitamin E met the primary endpoint compared to 19% of those who received a placebo.
A daily dose of specific vitamin E significantly improved NASH features in adults, while Actos showed promise but was associated with weight gain. Researchers acknowledge the need for long-term treatment and monitoring to assess benefits and risks.
Researchers have developed contact lenses loaded with vitamin E that can deliver more medication for glaucoma and other diseases to the eye, increasing treatment duration by about 100 times. Vitamin E's ant-oxidant properties also provide UV protection.
Researchers at Ohio State University found that tocotrienol form of natural vitamin E can prevent nerve cells from dying after a stroke by blocking the release of fatty acids. The study suggests that this form of vitamin E has distinct functions and offers a potential therapeutic target for preventing and treating strokes.
Researchers found that a three-year combination therapy of vitamin E, selenium, and soy did not prevent the progression from HGPIN to prostate cancer. The study results show that 26.4% of participants developed invasive prostate cancer, regardless of baseline characteristics.
A six-year vitamin E supplementation study found that high dietary vitamin C intake significantly influenced the effect of vitamin E on mortality in male smokers. Vitamin E decreased mortality by 41% in elderly smokers with high vitamin C intake, while increasing mortality by 19% in middle-aged smokers with similar intake levels.
A major study of over 14,000 male physicians found that long-term vitamin E and C supplementation had no significant impact on prostate cancer or total cancer risk. The study suggests that these supplements may not be effective in preventing cancer in middle-aged and older men.
A large cancer prevention trial found no association between supplementation with vitamin E or selenium and a reduced risk of prostate cancer. The study included 35,533 men and followed them for up to 7 years, concluding that these supplements were ineffective in preventing prostate cancer.
Research suggests Vitamin E's antioxidant properties may reduce pro-inflammatory cytokine expression in skeletal and cardiac muscle. The study found significant reductions in oxidized proteins and two cytokines with Vitamin E treatment compared to placebo, potentially correlating with increased muscle strength.
A large-scale clinical trial found no significant protection against cancer from long-term vitamin E or C supplements. Researchers followed over 14,000 physicians for up to 10 years without detecting a link between these supplements and reduced cancer rates.
A large, long-term study found that vitamins E and C supplements did not reduce the risk of major cardiovascular events in male physicians. Despite previous observational studies suggesting a role for these antioxidants in reducing coronary heart disease risk, the study found no significant effect on cardiovascular mortality or morbidity.
A case-series study found that rectal doses of d-alpha tocopherol reduced disease severity and promoted clinical remission in patients with active ulcerative colitis. The treatment's antioxidant and anti-inflammatory effects were likely responsible for the observed benefits.
Research suggests a shared metabolic pathway between vitamins E and K may cause interaction, diminishing vitamin K levels as vitamin E increases. The Women's Health Study found 24% fewer deaths from heart disease in women taking 600 IU vitamin E supplements.
A study found that people with Alzheimer's disease who took vitamin E lived 26% less likely to die than those who didn't take vitamin E. Vitamin E may be more beneficial when taken with a cholinesterase inhibitor.
A study published by the American Thoracic Society found that certain vitamin supplements, including multivitits, vitamin C, and folate, did not protect against lung cancer and may even increase the risk. The risk was highest among current smokers, with a seven percent rise in risk for every 100mg/day of supplemental vitamin E.
A six-year vitamin E supplementation increased TB risk by 72% in male smokers with high dietary vitamin C intake. Vitamin E had no effect on those with low dietary vitamin C intake.
Researchers at Yale School of Medicine discovered a significant association between low vitamin E levels and physical decline in older adults. The three-year study found that individuals with lower vitamin E levels experienced a 62% greater risk of declining in physical function.
A study found that low vitamin E levels are associated with a decline in physical function among older adults. The researchers suggest that oxidative stress and muscle damage may play a role in the relationship between vitamin E and physical decline.
Women with higher dietary intakes of lutein, zeaxanthin, and vitamin E have a lower risk of developing cataracts. These antioxidants may protect against cataract formation by filtering harmful blue light and damaging lens proteins.
Researchers found that despite strong contradictory evidence, favorable citations for vitamin E persisted in medical literature until 2005. For beta-carotene and estrogen, similar findings were observed, with a majority of citing articles remaining favorable even after contradicting evidence was published.
The levels of vitamin E necessary to reduce oxidative stress are far higher than those commonly used in clinical trials, according to new research. Vitamin E supplements at these levels may help prevent or treat cardiovascular disease by reducing oxidative stress and inflammation.
Researchers found that vitamin E's antioxidant effect is only significant at high doses, exceeding previously used amounts in clinical trials. The optimal dose was determined to be around 1600 IU/day for maximum suppression of oxidative stress.
A synthetic vitamin E derivative, á-TEA, has been shown to inhibit the spread of aggressive mammary cancer in mice when mixed into their food. The study found a 4.8-fold reduction in tumors that spread to the lungs, suggesting potential use as a dietary supplement for treating human metastatic breast cancer.
Research suggests that children whose mothers had low vitamin E intake during pregnancy are more likely to develop wheezing and asthma by age five. Vitamin E exposure was found to have a dual effect on lung function and airway inflammation, with effects differing between early and later pregnancy.
Researchers at Ohio State University found that moderate doses of tocotrienol, a natural form of vitamin E, reach concentrations in human blood plasma sufficient to protect against neurological damage following stroke. The supplement also exhibits non-antioxidant protection against neurodegeneration.
A new compound created from vitamin E has been shown to be a potent cancer killer by blocking the Bcl-xL protein and causing programmed cell death in cancer cells. The substance kills cancer cells without damaging healthy cells, offering new hope for cancer prevention and treatment.
Research found that beta carotene slows the decline in lung power, a critical indicator of lung function, associated with aging. The study showed that higher levels of beta carotene and vitamin E in the blood reduced the rate of decline in lung function, particularly in smokers.
A University of Toronto study found that increasing vitamin E levels during pregnancy may alter the onset of cancer in adult life. While it reduced in utero deaths, it also accelerated cancer development, suggesting a potential link between antioxidant intake and cancer risk.
Researchers found that gamma-tocopherol, commonly consumed through corn and soybean oil, destroys animal cells by preventing proper protein folding. In contrast, alpha-tocopherol does not have this effect. The study suggests a possible evolutionary explanation for the body's preference for alpha-tocopherol.
The study shows that vitamin C supplements can protect against the loss of vitamin E in smokers, reducing cancer risk. Smokers who took supplements had about the same level of antioxidant protection as non-smokers.
Research suggests that antioxidant supplementation with vitamin E, vitamin C, and beta-carotene is not associated with a decreased risk of prostate cancer. However, specific subgroups, such as current or recent smokers, may benefit from high-dose vitamin E supplementation to reduce advanced prostate cancer risk.
Researchers found that high-dose vitamin E supplementation improved rat lifespan, cognitive function, and neuromuscular performance. The results show a significant correlation between vitamin E levels and mitochondrial function, supporting the free radical theory of aging.
Scientists have developed techniques to analyze the chemical composition of brain cells, enabling them to map the distribution of biologically important molecules like vitamin E. This breakthrough may lead to a better understanding of brain function in healthy and diseased brains.
Researchers explored commercially important ingredients and delivery technologies in a symposium on cosmetic nanotechnology. Novel formulations, such as synthetic nanocarriers that encapsulate Vitamin E, were presented to improve skin and hair care products.
Researchers have discovered a novel probucol-analog that effectively protects against atherosclerosis without the same side effects as its predecessor. This breakthrough compound induces an anti-oxidative and anti-inflammatory pathway in blood vessel walls, offering new hope for treating people with or at risk of heart disease.
A large randomized clinical trial found that vitamin E supplementation did not reduce the risk of major cardiovascular events or cancer in healthy women. The study followed 39,876 women aged at least 45 years for an average of 10.1 years and found a 24% reduction in cardiovascular death, but no significant effect on other outcomes.
A large study of 39,876 healthy women found no effect of vitamin E on total cancer or cardiovascular disease. However, vitamin E supplementation was associated with a reduced risk of cardiovascular deaths among all women and a decrease in heart attacks and cardiovascular deaths among women aged 65 years and older.
A meta-analysis of eight studies suggests that moderate dietary vitamin E intake reduces the risk of developing Parkinson's disease. However, no protective effects were found for vitamin C or beta-carotene.