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Vitamin E may lower liver cancer risk

A recent study published in the Journal of the National Cancer Institute found that high vitamin E intake from diet or supplements is associated with lower liver cancer risk. The analysis included 132,837 individuals and showed a clear inverse dose-response relation between vitamin E intake and liver cancer risk.

SourceVanderbilt University Medical Center·JournalJNCI Journal of the National Cancer Institute·DateJul 17, 2012

Vitamin E may decrease and increase mortality of male smokers with high dietary vitamin C intake

A six-year vitamin E supplementation study found that high dietary vitamin C intake significantly influenced the effect of vitamin E on mortality in male smokers. Vitamin E decreased mortality by 41% in elderly smokers with high vitamin C intake, while increasing mortality by 19% in middle-aged smokers with similar intake levels.

SourceUniversity of Helsinki·JournalAmerican Journal of Epidemiology·DateFeb 14, 2009

Certain vitamin supplements may increase lung cancer risk, especially in smokers

A study published by the American Thoracic Society found that certain vitamin supplements, including multivitits, vitamin C, and folate, did not protect against lung cancer and may even increase the risk. The risk was highest among current smokers, with a seven percent rise in risk for every 100mg/day of supplemental vitamin E.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateFeb 29, 2008

Vitamin E trials 'fatally flawed'

The levels of vitamin E necessary to reduce oxidative stress are far higher than those commonly used in clinical trials, according to new research. Vitamin E supplements at these levels may help prevent or treat cardiovascular disease by reducing oxidative stress and inflammation.

SourceOregon State University·JournalFree Radical Biology and Medicine·DateSep 21, 2007

Nutritional friend or foe? Vitamin E sends mixed messages

Researchers found that gamma-tocopherol, commonly consumed through corn and soybean oil, destroys animal cells by preventing proper protein folding. In contrast, alpha-tocopherol does not have this effect. The study suggests a possible evolutionary explanation for the body's preference for alpha-tocopherol.

SourceOhio State University·JournalProceedings of the National Academy of Sciences·DateMar 2, 2006

Antioxidant supplementation not associated with decreased risk of prostate cancer

Research suggests that antioxidant supplementation with vitamin E, vitamin C, and beta-carotene is not associated with a decreased risk of prostate cancer. However, specific subgroups, such as current or recent smokers, may benefit from high-dose vitamin E supplementation to reduce advanced prostate cancer risk.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateFeb 14, 2006

Rethinking anti-oxidants

Researchers have discovered a novel probucol-analog that effectively protects against atherosclerosis without the same side effects as its predecessor. This breakthrough compound induces an anti-oxidative and anti-inflammatory pathway in blood vessel walls, offering new hope for treating people with or at risk of heart disease.