Articles tagged with Western Blot
Researchers found specific gene mutations in barley affect starch synthesis, forming elongated starch granules with altered properties. Mutations disrupt enzymes, altering glucose chain formation and branching.
Han Xiao aims to develop cells that can biosynthesize and utilize non-canonical amino acids as in vivo sensors for enzymes involved in posttranslational modifications. This research could lead to new strategies in treating diseases by providing real-time insights into enzyme activities.
Researchers at Case Western Reserve University have discovered a new sporadic prion protein disease, Variably protease-sensitive prionopathy (VPSPr), which shares genotype characteristics with Creutzfeldt-Jakob disease. The abnormal prion protein in VPSPr exhibits distinct characteristics different from other prion diseases.
A new diagnostic technique, conformation-dependent immunoassay (CDI), is being considered as the standard approach for brain biopsies of patients suspected of having prion disease. The study found that CDI detected prions in 100% of samples studied, while traditional tests failed to detect them in a high proportion of cases.