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Fluctuating cellular energy drives microbial bioproduction

A study led by Fuzhong Zhang found that microbes respond differently to various carbon sources, with acetate inducing high ATP levels in E. coli and oleate in Pseudomonas putida. This research provides insights into microbial energy homeostasis and offers a strategy to enhance bioproduction by choosing beneficial feedstocks.

New molecular sensor tracks energy use at the subcellular level

Researchers developed a high-resolution sensor to track real-time dynamics of ATP levels in cells and within subcellular compartments. The iATPSnFR2 sensor has high sensitivity across a wide range of ATP concentrations, enabling accurate tracking of ATP levels and their dynamics.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Unwinding the world’s smallest biological rotary motor by degrees

Scientists studied F1-ATPase function in bacteria to clarify the angle of rotation during ATP hydrolysis. The study revealed three sets of short and long dwells associated with different intervals per revolution, resolving a long-term debate over the ATP-cleavage shaft angle.