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Dreams drain energy: the REM sleep paradox

Researchers at Tohoku University discovered a paradox in REM sleep where the brain's energy molecule decreases despite an increase in fuel supply. This finding suggests that the brain dynamically adjusts its energy economy to support complex internal processing, revealing new insights into biological computation and sleep function.

SourceTohoku University·JournalCommunications Biology·DateJul 27, 2026
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Fluctuating cellular energy drives microbial bioproduction

A study led by Fuzhong Zhang found that microbes respond differently to various carbon sources, with acetate inducing high ATP levels in E. coli and oleate in Pseudomonas putida. This research provides insights into microbial energy homeostasis and offers a strategy to enhance bioproduction by choosing beneficial feedstocks.

SourceWashington University in St. Louis·JournalNature Communications·DateJul 1, 2024

New molecular sensor tracks energy use at the subcellular level

Researchers developed a high-resolution sensor to track real-time dynamics of ATP levels in cells and within subcellular compartments. The iATPSnFR2 sensor has high sensitivity across a wide range of ATP concentrations, enabling accurate tracking of ATP levels and their dynamics.

SourceWeill Cornell Medicine·JournalProceedings of the National Academy of Sciences·DateMay 16, 2024
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Unwinding the world’s smallest biological rotary motor by degrees

Scientists studied F1-ATPase function in bacteria to clarify the angle of rotation during ATP hydrolysis. The study revealed three sets of short and long dwells associated with different intervals per revolution, resolving a long-term debate over the ATP-cleavage shaft angle.

SourceTokyo University of Science·JournalBiophysical Journal·TypeExperimental study·DateMar 9, 2023