Articles tagged with Cell Development
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new Rutgers study suggests that food companies use the terms "cell-based" or "cell-cultured" when labeling seafood products made from fish cells. The study found that both terms meet FDA regulations and help consumers understand the production process, while also recognizing potential allergens.
A recent study published in eNeuro found that male-derived brain cells exhibit a stronger synaptogenic response to thrombospondin-2 compared to female-derived cells. This difference is driven by how neurons respond to the protein, resulting in varying synaptic formation mechanisms between sexes.
Researchers from Max Planck Institute of Molecular Physiology have developed a cell-based assay that identifies highly potent IDO1 inhibitors with different mechanisms of action, which could lead to promising immunotherapies for cancer treatment. The new approach overcomes limitations of existing cell-free assays and holds promise for ...
Researchers developed scVelo to estimate RNA velocity with an AI-based model, allowing them to study dynamic populations and understand cellular development and gene activity. This enables better understanding of disease progression and cell signaling, paving the way for personalized treatments.
A study published in Developmental Cell reveals the CMG2 protein interacts with collagen VI, regulating its concentration inside cells. In Hyaline Fibromatosis Syndrome, a mutation prevents CMG2 protein function, leading to collagen VI accumulation.
Researchers developed a computational method to measure intercellular forces without disturbing cell activity. The approach combines biophysical modeling with data-driven modeling using microscopy images.
A faulty signalling pathway is linked to left ventricular non-compaction (LVNC), a congenital heart condition where muscular projections fail to transform into compact heart muscle. The study provides new insights into the molecular mechanisms underlying LVNC and may lead to potential therapies.
Researchers have identified seven types of germ cell tumors, which are caused by failure of mechanisms that prevent spontaneous embryonal development. The new classification is valuable for future research, epidemiology, and clinical care, as it enables more reliable mapping of treatment sensitivity and resistances.
A new study created the first comprehensive genomic map of fat cells, revealing unique features that appear to 'hard-wire' different types of fat. The findings may guide future research into the drivers of harm arising from fat build-up in different parts of the body.
Research suggests that exposure to chemical mixtures present in household dust may contribute to increased growth in children relative to their age and promote the development of fat cells. The study found that very low concentrations of dust extracts were able to promote precursor fat cell proliferation and fat cell development.
Researchers at the University of Edinburgh have identified a crucial mechanism linking R-loops and Polycomb proteins to gene regulation in human cells. This finding has significant implications for understanding diseases associated with faulty Polycomb proteins or R-loop overproduction, including neurodegenerative disorders like ALS.
A new study found that GM12371, a specific long non-coding RNA, controls expression of multiple genes involved in nervous system development and functioning. It affects the developing neurons' shape and ability to signal, highlighting the importance of long noncoding RNAs in brain cell growth and signaling.
Harry Noller receives 2019 BPS Ignacio Tinoco Award for his pioneering studies on the structure, dynamics, and function of the ribosome. He is recognized for promoting an inclusive and collaborative research environment that positively impacts his community.
Researchers have developed LECs that emit bright light with a high brightness of 2,000 cd/m2 and an electron-to-photon efficiency of 27.5 percent, surpassing existing technologies like fluorescent tubes and LEDs. This breakthrough enables efficient and practical operation of LEC components in various fields.
The ASPM protein collaborates with katanin to regulate cell division and specialization into nerve cells, crucial for healthy brain development. A study published in Nature Cell Biology provides new insights into the molecular mechanisms underlying microcephaly.
Research by Osaka University identifies cohesin as key regulator of chromosome structure controlling nerve cell network formation and gene regulation. Mice with reduced cohesin expression exhibited neuronal defects, increased anxiety and behavioral problems.
The study reveals that CD38 is essential for postnatal glial cell development, particularly astrocytes. The gene's absence leads to retardation of glial cell development and aberrant interactions among cells, resulting in developmental disorders.
Researchers developed a method to generate primordial germ cell 'lookalike' cells, enabling the study of early stages of specification and regulation of developmental timings. This breakthrough opens up new avenues for understanding transgenerational epigenetic inheritance in humans.
Researchers found that genetic alterations causing congenital heart defects involve interactions between heart-forming tissues and the rest of the body. The study suggests that heart defects occur when the heart does not grow quickly enough to meet the demands of the developing body.
A new study reveals that genes within and outside the heart play a crucial role in determining the risk of congenital heart defects. The research found that Nipbl gene mutations can cause atrial septal defects, but only when combined with other genetic factors or environmental influences.
Researchers found that uncontrolled fluctuations in Retinoic acid levels can lead to disruptions in brain organization during development. Identifying the protein that interacts with RA to reduce noise may improve understanding of developmental disorders and guide future studies.
Researchers at UT Southwestern Medical Center have discovered that type I interferons can block the development of T helper 2 cells, which drive asthma and allergies. This finding offers new hope for treating allergic asthma patients by targeting this pathway.
Researchers have gained new understanding of how brain cells are formed and controlled by a key molecule miR-9, which is linked to brain development and function. This study could help explain what happens when cell production goes out of control in diseases like cancer.
Researchers discovered that sympathetic neurons communicate with pancreatic islet cells through norepinephrine, influencing their development and function. The study found deformities in the architecture of pancreatic islet cells and defects in insulin secretion and glucose metabolism in mutant mice.
Researchers at Carnegie Mellon University created an artificial cellular system with varying levels of molecular crowding to study its effects on gene expression. The findings suggest that tight quarters enhance gene expression in artificial cells.
Researchers at the Institute of Molecular Biology found that deletion of just one gene, Gadd45g, results in complete sex reversal of male mice. The study uncovers a novel signaling cascade essential for initiating male sex organ development.
A recent study confirms indoor tanning significantly increases non-melanoma skin cancer risk, especially among young people. Researchers estimate over 170,000 new cases annually in the US.
Researchers develop efficient algorithm to detect recurring patterns of interconnections in biological networks, shedding light on cellular processes and disease mechanisms. The approach has revealed novel motifs previously unrecognized, offering new insights into complex networks.
New technique allows scientists to observe development of brain cells for first time, shedding light on disease mechanism. The study could lead to new treatment options by understanding how these cells develop and function.
The 'life between the sheets' hypothesis proposes that structured compartments formed between layers of mica could have sheltered and evolved pre-life molecules. Mica's unique properties make it an ideal environment for life to emerge, with its ability to withstand wet/dry cycles and provide a stable surface for cells to develop.
Researchers at Risoe National Laboratory and Topsoe Fuel Cell will create prototypes of solid oxide fuel cells that meet market standards by 2012. The new project focuses on improving cell performance, durability, and production processes to reduce costs and emissions.
A new study by scientists at UCL reveals that the brains of newborn rats already possess a sense of direction and place, which improves with age. The research suggests that this innate ability could be independent of experience and provides insights into how our sense of space develops.
A protein called Pdx1 plays a previously unknown regulatory role in the development of immature endocrine system cells, ultimately giving rise to pancreatic islet cells. This discovery may facilitate beta-cell growth in labs and lead to new therapies for diabetes.
Researchers have identified a key molecule called Liar that leads other molecules into the nucleus of blood cells, offering a potential treatment for cancer. A cellular enzyme known as Lyn has also been found to 'turn on' blood cell development, highlighting a new target for cancer therapy.
Scientists have discovered a key to eye development - a protein called Pias3 that promotes rod cell formation and suppresses cone cell development. This breakthrough could lead to new treatment options for blinding conditions such as macular degeneration.
A protein complex regulating primary cilia formation has been identified by NYU researchers. The complex involves three proteins: CEP290, CP110, and Rab8a, which work together to promote cilia formation on mature cells. This discovery may lead to new drug targets for diseases such as polycystic kidney disease, retinal degeneration, and...
A team of researchers from the University of Illinois has made significant discoveries about germ cell development in planarians, a tiny flatworm species. They found that planarians express a key gene, nanos, which plays a critical role in germ cell formation and maintenance, similar to mammals.
Researchers at University of California, San Diego found a molecular link between chronic inflammation and cancer development. The protein p100 enables communication between inflammatory response and normal cell growth, but excessive levels may overactivate developmental pathways, leading to cancer.
A Northwestern University research team has developed a three-dimensional imaging technique that enables the study of fuel cell microstructure. This will help improve fuel cell performance and lifespan by revealing nanometer-scale features.
NIST researchers create a microfluidics technique to isolate and pattern neuronal cells on surfaces, allowing for the study of cell development and behavior. This breakthrough enables a variety of cell-geometry experiments, such as measuring the maximum gap between lines that can be bridged by neural axons and dendrites.
A scientist at the Marine Biological Laboratory has published a study showing that a combination of pollutants bromoform, chloroform, and tetrachloroethylene can alter nerve cell growth in clam embryos. The study found increased production of an enzyme involved in neural development, which may be linked to neurological disorders such a...
Researchers describe a process regulated by Hedgehog gene that induces formation of fast twitch muscles from slow twitch cells in zebrafish embryos. The findings provide insights into muscle development and potential models for muscular dystrophy.