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Wood formation can now be followed in real-time -- and possibly serve the climate of tomorrow

Researchers have developed a genetic engineering method to observe woody cell wall formation in plants, allowing them to better understand the mechanisms behind complex biological processes. This breakthrough could lead to the development of stronger construction materials with a smaller carbon footprint.

SourceUniversity of Copenhagen - Faculty of Science·JournalNature Communications·DateJan 28, 2021

Battling harmful algae blooms

A team of scientists, including Kathryn Coyne from the University of Delaware, have developed protocols for studying the genetic underpinnings of marine algae. By analyzing the genetics of a specific species of algae that produces harmful blooms, they were able to create genetically modified strains and identify genes involved in toxin...

SourceUniversity of Delaware·JournalNature Methods·DateJul 23, 2020

Cell wall research reveals possibility of simple and sustainable method to protect crops

Scientists have found that cell wall extracts from immune-active plants can trigger plant immunity and disease resistance, providing a new approach to protecting crops against pathogens and pests. This breakthrough discovery could lead to the development of simple, sustainable, and effective treatments to reduce crop losses.

SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·DateJun 15, 2020

Supercomputing improves biomass fuel conversion

Researchers used supercomputing and nano-imaging to reveal how a 'lignin-first' approach can facilitate the efficient breakdown of plant biomass. The study found that pretreating plant biomass with specific co-solvents, such as tetrahydrofuran and water, can help break down lignin and increase enzyme access to cellulose.

SourceUniversity of California - Riverside·JournalJournal of the American Chemical Society·DateAug 1, 2019

New chemical probes advance search for new antibiotics

Researchers at Indiana University have developed a new tool to observe living cells in real time under a microscope, advancing knowledge on how bacteria build their cell walls. This technology has significant value in addressing antibiotic resistance, which affects at least 2 million people in the US each year.

SourceIndiana University·JournalNature Chemistry·DateMar 1, 2019

Plant defense mechanisms

Researchers have identified multiple enzymes and channel proteins involved in plant defense mechanisms, including a reserve system that acts as backup for immune responses. The findings have practical utility for agriculture, such as cultivating crops that can resist different stresses more effectively.

Survival strategy: How one enzyme helps bacteria recover from exposure to antibiotics

Researchers at the University of Notre Dame discovered that lytic transglycosylase Slt helps gram-negative bacteria Pseudomonas aeruginosa recover from antibiotic damage by repairing its cell wall. The enzyme rapidly attempts to rebuild the organism's structural entity, allowing it to survive and continue causing infection.

SourceUniversity of Notre Dame·JournalProceedings of the National Academy of Sciences·DateApr 9, 2018

Less chewing the cud, more greening the fuel

A team of researchers has identified a gene involved in the stiffening of cell walls whose suppression increases the release of sugars by up to 60%. This breakthrough could lead to improved feed for ruminants and better biomass for biofuels, with potential global implications.

SourceRothamsted Research·JournalNew Phytologist·DateJan 7, 2018

Why plants form sprouts in the dark

Researchers identified a cell wall signal that initiates darkness programme in seedling development, enhancing survival. The signal is linked to metabolic breakdown products of pectin, allowing plant cells to communicate with each other about light conditions.

SourceRuhr-University Bochum·JournalCurrent Biology·DateNov 7, 2017

Revealed new target for development of antibiotics aimed at highly resistant bacteria

Researchers from Brazil and France identify a new target for developing antibiotics against highly resistant bacteria, inhibiting the interaction of two key proteins involved in cell wall elongation. The discovery paves the way for the development of antibiotics with a different action mechanism, offering hope in combating drug-resista...

Steering the immune defense against fungal pathogens

Researchers have developed bifunctional molecules that bind both chitin in fungal cell walls and human antibodies, redirecting the immune system to eliminate fungal pathogens. The new approach has shown synergistic effects with antifungal agents, holding promise for fighting echinocandin-resistant fungi.

SourceWiley·JournalAngewandte Chemie International Edition·DateSep 20, 2017

New approach to unlock the genetic potential of plant cell wall

The study provides detailed information about the genetics of crop plants, enabling breeders to identify key genes responsible for cell wall properties. By linking this data to specific changes in genetic information, researchers can make targeted improvements to support agricultural industries and biofuel production.

SourceUniversity of York·JournalProceedings of the National Academy of Sciences·DateJun 16, 2017

Modelling water uptake in wood opens up new design framework

A team of researchers from Germany and France has developed an equation of state for wood, which can predict water uptake in treated wood with a simple analytical model. This breakthrough could lead to the development of more environmentally friendly preservation treatments and bio-inspired smart actuators.

SourceIOP Publishing·JournalNew Journal of Physics·DateAug 23, 2016

New family of bacterial cell wall builders

Harvard Medical School scientists have identified a new family of proteins that virtually all bacteria use to build and maintain their cell walls. The discovery of this new family, called SEDS proteins, reveals potential targets for much-needed therapies that target the cell wall as a way to kill harmful bacteria.

SourceHarvard Medical School·JournalNature·DateAug 15, 2016