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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Mounting a multi-layered attack on fungal infections

Researchers have identified a three-pronged mechanism of the human immune system attacking fungal yeast cells, including recognition of specific cell wall components and glucan targets. Understanding these interactions could lead to effective immunotherapy and new treatments for patients with weakened immunity.

Advance in understanding cellulose synthesis

A study published in Nature Cell Biology has shed light on the protein network that provides scaffolding for cell-wall structure and delivers growth-promoting molecules. The research discovered a novel mechanism by which microtubules guide cellulose synthase complexes to their place of action.

Deceiving cell walls

Researchers have developed a new approach for treating pneumococci by emulating the choline architecture of their cell walls. This method traps critical pneumococcal proteins, preventing bacterial growth and toxin release. The resulting CBP inhibitor has a suitable dosage range for pharmaceuticals.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

New paper sheds light on bacterial cell wall recycling

Researchers at the University of Notre Dame have made significant discoveries about bacterial cell wall recycling. The study reveals that a specific enzyme, M1tB, plays a crucial role in breaking down the cell wall, leading to pro-inflammatory events associated with bacterial infections.

Researchers analyze how new anti-MRSA abtibiotics function

Researchers have discovered two new β-Lactam antibiotics that target MRSA, a major global health threat responsible for approximately 20,000 US deaths annually. The novel compounds interact with the MRSA cell wall enzyme PBP 2a, inhibiting its function and leading to bacterial cell death.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Scientists learning to create nanomaterials based on micro-algae patterns

Researchers are studying how unicellular micro-algae, known as diatoms, create complex cell walls and aim to learn from their intricate micro-architectures. Genetic engineering of diatoms using microparticle bombardment enables the insertion of mutated or foreign genes into the genome, potentially leading to novel silica nanostructures.

Tearing down the fungal cell wall

Scientists identify AbNPS2 gene crucial to fungal spore cell wall integrity, impacting viability and host plant damage. Disruption of the gene leads to structural changes, decreased germination rates, and reduced survival under adverse conditions.

Cell wall of pneumonia bacteria can cause brain and heart damage

Researchers at St. Jude Children's Research Hospital found that pieces of cell walls from Streptococcus pneumoniae bacteria hijack a protein on blood vessel lining and enter the brain and heart. Antibiotic therapy contributes to this damage by shedding more cell wall pieces.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Protein transformation gives new twist to medical research

A new protein, Lyz, has been discovered to transform into a different structure, enabling medical researchers to design drugs that can turn proteins on or off at the cellular level. This discovery could lead to treatment for difficult-to-cure diseases such as cancer and HIV.

More useful plants may sprout from gene role discovery

Purdue University researchers found a new twist in a plant formation biochemical pathway, decreasing two acids in plant cell walls to enhance digestibility. This could lead to more nutritious livestock feed and improved crop yields.

Simple sugars make cell walls like steel

Purdue University scientists discovered that simple sugars, particularly galactose, are essential for maintaining plant cell wall strength. The study found that enzymes break down xyloglucan polymers during growth, allowing microfibrils to separate and new fibers to be integrated, preventing the cell wall from becoming too thick.

Cloned gene may help crops and livestock meet future needs

Scientists at Purdue University have cloned a gene that improves the digestibility of food for livestock and enhances the stress tolerance of plants. The study's findings have potential applications in breeding more productive and resilient crop varieties.

Purdue scientists lead $5.9 million plant study to improve products

Researchers will use infrared spectroscopy to identify mutant genes affecting plant cell wall architecture in Arabidopsis and maize. The goal is to determine the function of all genes involved in plant cell walls, potentially leading to improvements in food-derived health benefits and product durability.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Scientists document water molecule movement across cell walls

Researchers at the University of Illinois have successfully simulated the movement of water molecules through aquaporins, ensuring only water passes between cells. The study reveals that water molecules pass single-file and reverse orientation midstream, preventing ion conduction and maintaining cell metabolism.

Complex carbohydrate found to regulate plant growth

Scientists have discovered that a complex carbohydrate, RG-II, plays a crucial role in regulating plant growth by forming a network in the cell wall matrix through boron cross-links. The ability of RG-II to cross-link with boron enables normal plant expansion and prevents dwarfing in mutants without sufficient boron or fucose.

Researchers identify novel penicillin-resistance gene in pneumonia bacteria

Researchers at Rockefeller University have identified two genes responsible for producing branched muropeptides, essential for pneumococcus survival in the presence of penicillin. Inactivating these genes restores penicillin's potency, opening the door to new drugs that target this newly discovered mechanism.

Plants Can Substitute Cell Wall Sugar

A team of researchers from the University of Georgia has discovered that plant cells can substitute one sugar for another in their cell walls, a process previously thought to be essential for survival. This finding suggests that oligosaccharins play a role in regulating cell wall growth and development.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.