Cellular Regulation

Scientists Link Body Weight Regulation And Immune System Control

Researchers discover a gene, mahogany, that regulates obesity in mice, linking it to the immune system. The protein, made inside cells, passes through membranes to detect hormones, potentially leading to new treatment options for obesity.

Computer Simulation Reveals Nano-Switch That Activates Cell-Binding Function Of Key Protein In The Body

Computer simulations reveal a tension-activated switch mechanism that regulates fibronectin's cell-binding function, similar to untying a shoelace. The researchers' findings provide new insight into how nature may use molecular mechanics to control biological activity.

Move Over, Protein Kinase C, You've Got Company: Munc13-1 Is A Novel Diacylglycerol Target That Modulates Neurotransmitter Release

Researchers identified Munc13-1 as a novel diacylglycerol target that regulates neurotransmitter release from nerve cells. This study reveals a new mechanism for neurotransmitter release beyond the well-known role of Protein Kinase C.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Scientists Identify A Novel Mitotic Regulatory Mechanism

Researchers identified a specialized protein that catalyzes conformational change of mitotic proteins, allowing correct exit from mitosis. This finding has significant implications for understanding and developing anti-cancer agents targeting this mechanism.