Recent research reveals a master regulator protein that prevents DNA replication at the wrong time in the cell cycle, ensuring each progeny cell has the correct number of gene-bearing chromosomes. This discovery could lead to new design principles for operating autonomous devices.
Researchers discover a gene, mahogany, that regulates obesity in mice, linking it to the immune system. The protein, made inside cells, passes through membranes to detect hormones, potentially leading to new treatment options for obesity.
Computer simulations reveal a tension-activated switch mechanism that regulates fibronectin's cell-binding function, similar to untying a shoelace. The researchers' findings provide new insight into how nature may use molecular mechanics to control biological activity.
Researchers identified Munc13-1 as a novel diacylglycerol target that regulates neurotransmitter release from nerve cells. This study reveals a new mechanism for neurotransmitter release beyond the well-known role of Protein Kinase C.
Researchers identified a specialized protein that catalyzes conformational change of mitotic proteins, allowing correct exit from mitosis. This finding has significant implications for understanding and developing anti-cancer agents targeting this mechanism.