Researchers have mapped the structure and mechanics of a critical cellular machine that malfunctions in people with rare genetic disorders. The discovery could lead to new treatments and faster diagnoses for children with conditions like infantile encephalopathy, corpus callosum hypoplasia, and Kenny-Caffey syndrome.
SourceUniversity of California - Davis·JournalScience Advances·TypeExperimental study·DateMay 8, 2026
Researchers redesigned a key component of lipid nanoparticles to steer particles toward lymph nodes, reducing off-target delivery. This advancement could make mRNA vaccines more efficient, potentially achieving strong immune protection at lower doses.
SourceUniversity of Pennsylvania School of Engineering and Applied Science·JournalJournal of the American Chemical Society·TypeExperimental study·DateMar 24, 2026
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
For the first time, researchers have directly visualized how newly formed cellular organelles leave the endoplasmic reticulum and transition onto microtubule tracks inside living cells. The study reveals that the ER plays an active role in steering intracellular traffic.
SourceInstitute for Basic Science·JournalACS Nano·TypeExperimental study·DateJan 28, 2026
Researchers have discovered the ExHOS nanomachine, which controls constitutive exocytosis by delivering spherical molecular packages to the cell surface. This process is essential for preserving cell fitness and vital functions such as communication and growth.
SourceUniversitat Pompeu Fabra - Barcelona·JournalCell·TypeExperimental study·DateJan 16, 2026
Scientists at the University of Tsukuba have identified a system to transport excess reactive sulfur species out of cells, maintaining redox homeostasis and preventing oxidative stress. This discovery opens new avenues for research into sulfur stress and related diseases.
SourceUniversity of Tsukuba·JournalRedox Biology·DateOct 31, 2022
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers developed a new method to study membrane proteins in their native environment, the cell, using electron spin resonance spectroscopy. This technique allows for precise determination of protein properties and could lead to better understanding and targeting of membrane proteins involved in anti-cancer drug resistance.
SourceUniversité de Genève·JournalScience Advances·TypeNews article·DateOct 24, 2022
The study reveals a specialized transport hub at the base of cilia, where trains assemble and load cargo for transport. This discovery provides new insights into molecular basis for various diseases, including cystic kidneys and blindness.
Researchers have gained insight into the electronic structure of hydrated proton complexes, revealing that three inner water molecules are drastically modified by the proton. The first hydration shell senses the electric field of the proton through Coulomb interactions.
SourceMax Born Institute for Nonlinear Optics and Short Pulse Spectroscopy (MBI)·JournalAngewandte Chemie International Edition·TypeExperimental study·DateSep 19, 2022
Researchers have developed a new labeling technique to analyze exosomes from specific cell types, providing insights into their role in both health and disease. The technique allows for the identification of protein cargo and RNA in exosomes, enabling the study of cellular communication and potential monitoring of response to treatment.
SourceMedical College of Georgia at Augusta University·JournalJournal of Extracellular Vesicles·DateAug 30, 2022
Researchers at Washington University in St. Louis found that cancer cells metabolize glucose in their mitochondria, following conventional biochemical patterns. The study suggests that limiting glucose uptake may not be an effective strategy to target cancer cells, and glucose metabolism may need to be reevaluated as a therapeutic target.
SourceWashington University in St. Louis·JournalMolecular Cell·TypeExperimental study·DateAug 15, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Scientists have developed a smart contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions, which hold promise for cancer diagnostics. The lens was designed to bind to antibodies capturing exosomes found in tears, offering a potential platform for non-invasive cancer screening.
SourceTerasaki Institute for Biomedical Innovation·JournalAdvanced Functional Materials·TypeExperimental study·DateAug 11, 2022
The study found that plants have a transport route for calcium ions into their mitochondria, which is essential for signal transmission. The researchers also discovered a link between calcium ion transport and the regulation of the plant hormone jasmonic acid, which controls defense against herbivores and senescence.
SourceUniversity of Münster·JournalThe Plant Cell·DateAug 10, 2022
The Gerlich Group at IMBA found that histone acetylation establishes a sharp surface boundary on chromosomes, resisting microtubule perforation. Chromatin phase separation and DNA looping by condensin cooperates to build mitotic chromosomes with unique physical properties.
SourceIMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences·JournalNature·TypeExperimental study·DateAug 3, 2022
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers developed artificial microtubules to transport microscopic cargo along magnetic stepping stones, overcoming fluid flow obstacles. The technology could facilitate targeted drug delivery and treat blocked vessels or cancerous tumors.
SourceUniversity of Pennsylvania·JournalNature Machine Intelligence·TypeExperimental study·DateJul 21, 2022
Researchers at Tokyo Institute of Technology have successfully synthesized a synthetic mechanosensitive potassium channel, exhibiting stimuli responsiveness and selective ion transport. The new ion channel could lead to breakthroughs in therapeutic treatments for ion-channel related diseases.
SourceTokyo Institute of Technology·JournalJournal of the American Chemical Society·TypeExperimental study·DateJul 15, 2022
A novel peptide has been developed for targeted transport of molecules, including active substances and dyes, into mammalian cells. The peptide interacts with an acidic partner peptide to facilitate precise delivery.
SourceUniversität Bayreuth·JournalNature Chemical Biology·TypeNews article·DateJul 14, 2022
Researchers have identified a family of proteins called PIN-FORMED as essential for auxin transport, guiding plant growth and development. The discovery provides the first structural basis of auxin transport by PIN proteins and sheds light on how herbicides can be recognized by these proteins.
SourceAarhus University·JournalNature·TypeExperimental study·DateJun 29, 2022
Scientists identify PiT2-loop7 missense mutations causing inorganic phosphate dyshomeostasis, leading to primary familial brain calcification. The study reveals how these mutations affect PiT2 phosphorylation and membrane localization, reducing Pi transport activity.
SourceChinese Academy of Sciences Headquarters·JournalNeuroscience Bulletin·DateJun 24, 2022
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers used fluorescence microscopy to study clathrin-mediated endocytosis in living cells. They found evidence of three models of curvature initiation and discovered that short-lived events favored the constant-curvature model, while longer events preferred the flat-to-curved transition pathway.
SourceUniversity of Alabama at Birmingham·JournalNature Communications·TypeExperimental study·DateJun 13, 2022
A team of researchers from Kumamoto University has developed a transformable polyrotaxane carrier that can facilitate genome editing using Cas9RNP with high efficiency. The carrier, called amino-PRX, is multi-step transformable and has low cytotoxicity, making it an enormously promising candidate for safe and efficient delivery.
SourceKumamoto University·JournalApplied Materials Today·TypeExperimental study·DateMay 11, 2022
Research reveals extracellular vesicles facilitate coordinated responses among pathogenic fungal cells, enabling them to overcome host defenses. The discovery could lead to the development of more effective therapies to combat fungal infections.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalmBio·DateMar 30, 2022
Researchers at Arizona State University have developed a hybrid device that combines living organisms with bio batteries to produce stored energy under light conditions. The technology, known as microbial electro photosynthesis, has the potential to power a wide range of products, including transportation fuels and cosmetics.
SourceArizona State University·JournalJournal of the American Chemical Society·TypeExperimental study·DateFeb 20, 2022
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers at the University of Eastern Finland used molecular modeling to investigate nano-plastic transport into cell membranes. The study found that some microplastics can passively penetrate the membrane, potentially causing adverse health effects.
SourceUniversity of Eastern Finland·JournalScientific Reports·DateFeb 17, 2022
A study led by Przemyslaw Nogly at PSI has detailed insight into the mechanism of a light-driven chloride pump in bacteria, revealing how light energy converts to kinetic energy and transports chloride ions inside cells. The pump uses two molecular gates to ensure one-way transport, with the process taking around 100 milliseconds.
SourcePaul Scherrer Institute·JournalScience·TypeExperimental study·DateFeb 3, 2022
Researchers at Simon Fraser University discovered that the number of molecular machines affects system performance, highlighting a key design principle for optimizing collective behavior.
SourceSimon Fraser University·JournalNew Journal of Physics·TypeMeta-analysis·DateJan 17, 2022
Scientists at the University of Missouri discovered that bisphenol A (BPA) exposure during pregnancy can negatively impact fetal brain development. MicroRNAs in the placenta play a key role in regulating cellular functions, including neural development. Researchers believe that microRNA packages could reach the brain through the placen...
SourceUniversity of Missouri-Columbia·JournalEpigenomics·DateJan 12, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
The study provides a comprehensive model of the yeast nuclear pore complex, shedding light on its core scaffold and functional adaptations. This discovery may help understand how viruses infect cells and alter their physiology to cause disease.
SourceBoston University School of Medicine·JournalCell·TypeComputational simulation/modeling·DateJan 3, 2022
Researchers have discovered that specific regions of HAT family proteins determine which amino acids they bind to, leading to unique functions in cell growth and diseases like cancer and neurodegenerative disorders. This knowledge will enable efforts to develop compounds targeting these proteins for therapy.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalProceedings of the National Academy of Sciences·DateNov 29, 2021
A new viral disease caused by Tomato brown rugose fruit virus (ToBRFV) has emerged, threatening global tomato production. ToBRFV overcomes the durable Tm-2² resistance gene, which had remained unbroken for over half a century.
SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·TypeExperimental study·DateNov 2, 2021
Researchers at IRB Barcelona have identified γTuRC as a centriole stabilizer, revealing its role in maintaining centriole stability and preventing microcephaly. The study's findings suggest that defects in γTuRC may contribute to various human diseases, including adolescent scoliosis and male infertility.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalNature Communications·TypeExperimental study·DateNov 1, 2021
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers discovered that living cell interiors become softer and more fluid during mitosis, a process crucial for life. The findings could help ensure precise separation of cellular structures into daughter cells.
SourceUniversity of Göttingen·JournalNature Physics·TypeImaging analysis·DateOct 21, 2021
A research team from the University of Zurich has identified a common genetic variant in the AQP1 gene that affects treatment efficacy and patient survival on peritoneal dialysis. Patients carrying this variant have a higher risk of death, but researchers found a way to circumvent the problem using colloid osmotic agents.
SourceUniversity of Zurich·JournalNew England Journal of Medicine·TypeExperimental study·DateOct 20, 2021
Jochen Zimmer, a UVA professor, has been awarded $9 million by the HHMI to pursue his research on biopolymer transport across biological membranes. His work aims to develop new biomaterials for medicines, food, and energy, potentially combating diseases, hunger, and climate change.
Researchers aim to produce enough mRNA vaccines from spinach and lettuce to rival traditional shots. They're exploring chloroplasts as a key to making plant-based mRNA vaccines that can be stored at room temperature.
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers have identified a new transport pathway for cellular waste that passes through the cell nucleus's membrane, allowing damaged proteins to be removed from the genome. This discovery has potential implications for treating cancers and neurodegenerative diseases.
SourceUniversity of Gothenburg·JournalProceedings of the National Academy of Sciences·TypeSurvey·DateSep 1, 2021
Scientists developed a new mouse line to study protein balance and quality control in the mammalian brain. The research revealed that different neurodegenerative diseases have distinct protein misfolding patterns, offering insights into potential therapeutic options.
SourceMax-Planck-Gesellschaft·JournalThe EMBO Journal·DateAug 19, 2021
Scientists at Sanford Burnham Prebys have gained insight into the process of autophagy, where cells degrade and recycle cellular components. The study reveals that a chemical modification helps direct the transport of autophagosomes to cellular recycling plants, potentially leading to new targets for age-related diseases.
SourceSanford Burnham Prebys·JournalCurrent Biology·DateJun 18, 2021
Researchers at LMU München found that diffusiophoresis can facilitate directed particle transport in cells, even without motor proteins. The mechanism sorts particles by size and has implications for understanding cellular processes and potential applications in artificial minimal cells.
SourceLudwig-Maximilians-Universität München·JournalNature Physics·DateApr 6, 2021
Researchers at NUST MISIS developed a new structure for perovskite solar cells using MXenes, increasing power conversion efficiency to over 19%. The modified cells show superior performance and improved stabilized power output compared to reference devices.
SourceNational University of Science and Technology MISIS·JournalNano Energy·DateFeb 9, 2021
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
New theories have enabled researchers to model unusual dynamics where particle motions are no longer influenced by previous events. The 'memory term' principle allows studying this effect in a broader range of situations, particularly for advanced materials that respond to their environment.
SourceSpringer·JournalThe European Physical Journal E·DateNov 19, 2020
Researchers from ICIQ and IRBBarcelona have developed a synthetic carrier that can transport amino acids, such as Proline, across cell membranes. The study shows a 30-fold increase in L-Proline transport activity, opening up new possibilities for treating diseases related to amino acid metabolism.
SourceInstitute of Chemical Research of Catalonia (ICIQ)·JournalChem·DateOct 6, 2020
Researchers at Northwestern University have developed a new cell perturbation system that can deliver DNA, RNA, and proteins into cells with high efficiency and low toxicity. The Nanofountain Probe Electroporation system has the potential to revolutionize medical treatments by enabling quicker and more customized treatment plans.
SourceNorthwestern University·JournalSmall·DateOct 2, 2020
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A research team led by Prof. Dr. Robert Grosse has found that bundled fibers of actin play a crucial role in the expansion of cell nuclei after division. This process is essential for reorganizing genetic information and processing chromatin.
SourceUniversity of Freiburg·JournalEMBO Reports·DateSep 22, 2020
Researchers at Florida State University have discovered a key role for an adaptor protein in forming the outer structure of vesicles, which are essential for transporting molecules within cells. This finding sheds new light on how cells move resources and could potentially lead to breakthroughs in drug delivery and virus entry prevention.
SourceFlorida State University·JournalScience Advances·DateJul 23, 2020
Researchers developed a tiny plastic robot that moves under the influence of light and magnetism, allowing it to attract and capture contaminant particles from the surrounding liquid or pick up and transport cells. The robot operates independently of the water composition, making it suitable for use in contaminated water.
SourceEindhoven University of Technology·JournalProceedings of the National Academy of Sciences·DateJul 14, 2020
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A recent study by KU Leuven researchers has discovered a link between a defective ATP13A2 gene and cell death in Parkinson's disease. The study found that the gene plays a crucial role in transporting polyamines, essential molecules supporting various cellular functions.
Researchers at the University of Basel have developed biocompatible polymer vesicles that can enter the cell nucleus, allowing for targeted drug delivery. The nanocontainers can be designed to transport therapeutic agents directly to the cell's control center.
SourceUniversity of Basel·JournalProceedings of the National Academy of Sciences·DateJan 27, 2020
Researchers at the University of Basel have discovered a cellular machine called FERARI that sorts out reusable proteins for recycling, introducing a new 'kiss-and-run' mechanism. This process saves energy and time by reusing valuable cell components, potentially mitigating diseases associated with disrupted recycling processes.
SourceUniversity of Basel·JournalNature Cell Biology·DateJan 27, 2020
A study found that silencing the KPNA4 gene reduces cell proliferation, migration ability and resistance to radiation in HNSCCs. Targeting disease-specifically altered transport systems may serve as promising therapeutic strategies for cancer treatment.
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A team of researchers at LMU in Munich has found that messenger RNAs are transported between the cell body and nerve processes like sushi on an endless conveyor belt, allowing them to reach specific synapses. The discovery sheds light on how proteins are delivered to synapses, a crucial process for learning and memory.
SourceLudwig-Maximilians-Universität München·JournalNature Communications·DateJul 25, 2019
Researchers developed a novel computational approach to assign functions to unknown genes, revealing transporters play a critical role. The study highlights the importance of environmental conditions shaping minimal genomes and paves the way for focused research on essential and facilitator gene sets.
SourceUniversity of Kent·JournalNature Communications·DateJul 15, 2019
Researchers at the University of Bern have determined the structure of monocarboxylate transporter 4 (MCT4), a key protein in cancer cell metabolism. The study provides insights into the molecular mechanism of MCT4 and identifies promising binding sites for inhibitors, paving the way for new cancer treatments.
SourceUniversity of Bern·JournalNature Communications·DateJun 20, 2019
A new microfluidic organ chip model of the human blood-brain barrier has been developed, allowing for in vivo-like transport of drugs and therapeutic antibodies. The model recapitulates the physical barrier functions and transport abilities of the human BBB, offering a significant advance in drug development.
SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalNature Communications·DateJun 13, 2019
Scientists at Scripps Research have discovered how neurons manage mitochondrial transport, a process crucial for nerve cell function and energy production. The study found that cAMP signaling enhances mitochondrial transport after synapse formation, requiring significant energy to maintain communication between cells.
SourceScripps Research Institute·JournalCell Reports·DateJan 16, 2019
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers at WashU Medicine have identified a protein responsible for transporting nicotinamide mononucleotide (NMN) into cells, where it can be used to produce energy. This finding has implications for understanding the process of aging and developing therapies to boost cellular energy levels.
SourceWashU Medicine·JournalNature Metabolism·DateJan 7, 2019
A team of scientists has identified a previously unknown protein structure that enables the controlled intake of potassium ions into cells. The discovery, published in Nature Communications, reveals a complex mechanism involving two inter-subunit half-channels and challenges existing theories on potassium transport.
SourceGoethe University Frankfurt·JournalNature Communications·DateNov 26, 2018
E. coli's KdpFABC transport system uses a unique combination of pore and transporter to import potassium ions into the cell, blurring the boundaries between passive transport and active transport complexes. This discovery challenges the long-held dogma that these two systems are mutually exclusive.
SourceUniversity of Groningen·JournalNature Communications·DateNov 26, 2018
Scientists at IOCB Prague have discovered a previously unknown passive mechanism by which positively charged short peptides can penetrate cells. This process is based on membrane fusion induced by the transported peptides and shares the same mechanistic basis as known processes in neurons during nerve impulses.
SourceInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague)·JournalProceedings of the National Academy of Sciences·DateNov 8, 2018
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A new scalable means of applying an electron transport layer in perovskite cells has been developed, resulting in a 30 percent efficiency gain. This breakthrough could make perovskite solar cells more commercially viable and pave the way for record-breaking p-i-n perovskite solar cells.
SourceNYU Tandon School of Engineering·JournalNanoscale·DateJun 21, 2018
Scientists have developed a method to track protein movement using nanosensors, allowing for the observation of protein distribution and transport within cells. The technique uses genetically altered nanobodies that can fluoresce, enabling researchers to follow protein pathways in living cells.
SourceUniversity of Basel·JournalProceedings of the National Academy of Sciences·DateJun 18, 2018