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For yeast, a DNA break ensures sex switch for a grandchild

Researchers have identified a novel imprinting mechanism in yeast that controls sexual switching by marking genomic DNA with a simple single-strand break. This breakthrough discovery has general implications for how DNA can be marked for asymmetric inheritance affecting cell destiny.

Mitochondria findings may help beat wide range of disease

Researchers discovered mitochondria can fuse without additional proteins, revealing new insights into the aging process and potential treatments for age-related diseases. This understanding is crucial for developing new therapies for optic atrophy, Charcot-Marie-Tooth disease, and neurodegenerative disorders.

Artificial prions created

Scientists have identified amino acid sequences that allow prions to aggregate and replicate, leading to the creation of an artificial yeast prion. This breakthrough sheds light on the mechanisms behind diseases like mad cow disease and Alzheimer's, potentially paving the way for new treatments.

Tissue cells can revert to stem cells

Researchers have discovered that tissue cells in clusters of 4 and 8 can revert to a stem-cell state under specific conditions, working just as well as normal stem cells. This finding could provide a new approach for harnessing differentiated cells to enhance tissue repair, similar to animals that can regenerate lost parts.

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Stem cell death gives clue to brain cell survival

Scientists have identified a signal that triggers half of the stem cells in the developing brain to commit suicide at a certain point in development. This finding may one day help victims of devastating brain diseases such as Alzheimer's, Parkinson's, and stroke by understanding cell death and potential recovery mechanisms.

Stem cell death gives clue to brain cell survival

Researchers at UGA have identified a lipid-protein duo causing massive stem cell death during brain development, but also hinting at potential recovery mechanisms for devastating diseases like Alzheimer's and Parkinson's. The study reveals that this 'deadly couple' leads to the survival of cells destined to form neurons.

Missing protein is double-edged sword in cancer development

The E2F3 protein plays a crucial role in controlling cell division. A study found that its absence can lead to increased genetic instability and centrosome proliferation, which may contribute to cancer development. The researchers discovered that cells without E2F3 were more likely to develop into tumors, especially when combined with ...

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Gene found that controls stomatal cell growth in plants

Researchers at Ohio State University have discovered a gene that controls the growth of stomatal cells in plants, which could lead to enhanced crop plant development. The TMM gene is involved in the formation and distribution of stomatal cells on leaf surfaces, and its discovery may provide new insights into stem cell biology.

How brain cells “remember” their birth order

Researchers found that Drosophila neural precursor cells sequentially activate four different transcription factors, allowing them to maintain differences based on their time of birth. This 'memory' is crucial for normal brain development and may have implications for understanding human neural development.

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